| Tag | Content |
|---|---|
| Uniprot ID | A0A287AP23 |
| Entrez ID | |
| Genbank protein ID | HDB20666.1; HDC68175.1; |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSSSCP00000045648 |
| Ensembl nucleotide ID | ENSSSCG00000034468 |
| Gene name | BAG family molecular chaperone regulator 4 isoform 1 |
| Gene symbol | BAG4 |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSALRRSGYG PGDGPSYGRY YGPGGGDVPV HPPPPIYPPR PEPPQPPVSW RVRGGGQAET 60 TWPGEGGGGD GYYPSGGVWS EPGRAGGSHQ EQPPYPSYNS NYWNSPARPR APYPSTYPVR 120 PEMQGQNLNS YTNGAYGPPY PTGPGTNPAS YSGAYYTPGY AQTSYSTEVP STYRSPGNSP 180 TPVSRWMYPQ QDCQTEAPPL RGQVSGYPAS QNPGMSVPHY PYGDGNRSVP QPGPTVRPQE 240 DAWAPPGTYG VGTRYPWPAA SPSAPPGSLY VSESASSWPS SGSPQPPPSP PPPQPKDSSY 300 PYSQSDQGMS RHSFPCSVHQ YESSGTMNSD DSELLDSQVQ YSAEPQLYGH ASNEHPSNQD 360 PSNNLPDECL SSDEGTPPSI KKIIHVLEKV QYLEQEVEEF VGKKTDKAYW LLEEMLTKEL 420 LELDSVETGG QDTVRQARKE AVCKIQAILE KLEKKGL 457 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | BAG4 | 516353 | F1MSS9 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | BAG4 | 607954 | E2R7V4 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | BAG4 | 102179734 | A0A452FDQ9 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | BAG4 | 100057730 | F6RTR6 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | BAG4 | 9530 | O95429 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Bag4 | 67384 | Q8CI61 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | BAG4 | H2QW14 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | BAG4 | A0A287AP23 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | BAG4 | 100353212 | G1T9D0 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Bag4 | F1M3K6 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | bag4 | 100001980 | B8JJ17 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005829 | cytosol |
| GO:0005634 | nucleus |
| GO:0005886 | plasma membrane |
| GO:0051087 | chaperone binding |
| GO:0031625 | ubiquitin protein ligase binding |
| GO:0071364 | cellular response to epidermal growth factor stimulus |
| GO:0071356 | cellular response to tumor necrosis factor |
| GO:2001145 | negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity |
| GO:1903215 | negative regulation of protein targeting to mitochondrion |
| GO:0030838 | positive regulation of actin filament polymerization |
| GO:0045785 | positive regulation of cell adhesion |
| GO:0010763 | positive regulation of fibroblast migration |
| GO:0033138 | positive regulation of peptidyl-serine phosphorylation |
| GO:0051897 | positive regulation of protein kinase B signaling |
| GO:0051496 | positive regulation of stress fiber assembly |
| GO:0072659 | protein localization to plasma membrane |
| GO:0097178 | ruffle assembly |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| PROSITE ID | PROSITE Term |
|---|---|
| PS51035 | BAG |
| Pfam ID | Pfam Term |
|---|---|
| PF02179 | BAG |