Gene: BAG4

Basic information

Tag Content
Uniprot ID F1MSS9
Entrez ID 516353
Genbank protein ID
Genbank nucleotide ID NM_001110532.1
Ensembl protein ID ENSBTAP00000017468
Ensembl nucleotide ID ENSBTAG00000013143
Gene name BCL2 associated athanogene 4
Gene symbol BAG4
Organism Bos taurus
NCBI taxa ID 9913
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MSALRRSGYG PSDGPSYGRY YGPGGGDVPV HPPPPIYPPR PEPPQPPISW RGRGGGPAET 60
TWPGEGGGGD GYYASGGAWS EPGRAGGGHQ EQPPYPSYNS NYWNSAARPR APYPSTYPVR 120
PEMQSQSLNS YTNGGYGPPY PTGPGTNTAS YPGAYYTPGY AQTNYSTEVP STYRSPGNSP 180
TPVSRWMYPQ QDCQTEAPPL RGQVPGYPAS QNPGMSVPHY PYGDGNRSVP QPGPPVRPQE 240
DSWAPPGAYG MGTRYPWPSA APSGPPGSLY MNESTSSWPS SGSPQSPPSP PPPQPKDSSY 300
TYSQPDQGMS QHNFPCNVHQ YESSGSVNDD SSELLDPQVQ YSAEPHLYGN ASHEHPSTQD 360
QGNHLAEECL SSDEGTPPSI KKIIHVLEKV QYLEQEVEEF VGKKTDKAYW LLEEMLTKEL 420
LELDSVETGG QDSVRQARKE AVCKIQAILE KLEKKGL 457

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologBAG4516353F1MSS9Bos taurusPredictionMore>>
1:1 orthologBAG4607954E2R7V4Canis lupus familiarisPredictionMore>>
1:1 orthologBAG4102179734A0A452FDQ9Capra hircusPredictionMore>>
1:1 orthologBAG4100057730F6RTR6Equus caballusPredictionMore>>
1:1 orthologBAG49530O95429Homo sapiensPublicationMore>>
1:1 orthologBag467384Q8CI61Mus musculusPredictionMore>>
1:1 orthologBAG4H2QW14Pan troglodytesPredictionMore>>
1:1 orthologBAG4A0A287AP23Sus scrofaPredictionMore>>
1:1 orthologBAG4100353212G1T9D0Oryctolagus cuniculusPredictionMore>>
1:1 orthologBag4F1M3K6Rattus norvegicusPredictionMore>>
1:1 orthologbag4100001980B8JJ17Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005829 cytosol
GO:0005634 nucleus
GO:0005886 plasma membrane
GO:0051087 chaperone binding
GO:0031625 ubiquitin protein ligase binding
GO:0071364 cellular response to epidermal growth factor stimulus
GO:0071356 cellular response to tumor necrosis factor
GO:2001145 negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity
GO:1903215 negative regulation of protein targeting to mitochondrion
GO:0030838 positive regulation of actin filament polymerization
GO:0045785 positive regulation of cell adhesion
GO:0010763 positive regulation of fibroblast migration
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0051897 positive regulation of protein kinase B signaling
GO:0051496 positive regulation of stress fiber assembly
GO:0072659 protein localization to plasma membrane
GO:0097178 ruffle assembly

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR039773 BAG_chaperone_regulator
IPR036533 BAG_dom_sf
IPR003103 BAG_domain

PROSITE

PROSITE ID PROSITE Term
PS51035 BAG

Pfam

Pfam ID Pfam Term
PF02179 BAG