| Tag | Content |
|---|---|
| Uniprot ID | G1T9D0 |
| Entrez ID | 100353212 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_002720783.3 |
| Ensembl protein ID | ENSOCUP00000013235 |
| Ensembl nucleotide ID | ENSOCUG00000015405 |
| Gene name | BCL2 associated athanogene 4 |
| Gene symbol | BAG4 |
| Organism | Oryctolagus cuniculus |
| NCBI taxa ID | 9986 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSALRRSGYG PSDGPSYGRY YGPGGGDVPV HPPPPLYPHL RPEPPQPPIS WRVRGGGPAE 60 TTWPGEGGGG DGYYPTGGAW SDSGRAGGSH QEQPPYPNYN SNYWNSTARH RAPYPSTYPT 120 RPELQGQSLN SYTNGAYGPP YPPGAGASTA SYSGAYYTPG YTQANYSTEV PGTYRSPGNS 180 PTPVSRWVYP QQDSQTEVPP LRGQVPGYPA SQNPGMTLPH YPYGDGNRSV PQSVPSVRPQ 240 EDAWASSGAY GMGARYPWPS AVPTAPPGNL YVTENASPWP SSGSPQPPPS PPPQQPKESS 300 YPYSQSDQGM NRHSFPCSVR HQYESSGTVN NDNSELLDSQ VQYSAEPQLY GSATHEHLSN 360 QDQSHNLPEE SLSSDESTPP SIKKIIHVLE KVQYLEQEVE EFVGKKTDKA YWLLEEMLTK 420 ELLELDSVET GGQDSIRQAR KEAVCKIQAI LEKLEKKGL 459 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | BAG4 | 516353 | F1MSS9 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | BAG4 | 607954 | E2R7V4 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | BAG4 | 102179734 | A0A452FDQ9 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | BAG4 | 100057730 | F6RTR6 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | BAG4 | 9530 | O95429 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Bag4 | 67384 | Q8CI61 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | BAG4 | H2QW14 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | BAG4 | A0A287AP23 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | BAG4 | 100353212 | G1T9D0 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Bag4 | F1M3K6 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | bag4 | 100001980 | B8JJ17 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005829 | cytosol |
| GO:0005634 | nucleus |
| GO:0005886 | plasma membrane |
| GO:0051087 | chaperone binding |
| GO:0031625 | ubiquitin protein ligase binding |
| GO:0071364 | cellular response to epidermal growth factor stimulus |
| GO:0071356 | cellular response to tumor necrosis factor |
| GO:2001145 | negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity |
| GO:1903215 | negative regulation of protein targeting to mitochondrion |
| GO:0030838 | positive regulation of actin filament polymerization |
| GO:0045785 | positive regulation of cell adhesion |
| GO:0010763 | positive regulation of fibroblast migration |
| GO:0033138 | positive regulation of peptidyl-serine phosphorylation |
| GO:0051897 | positive regulation of protein kinase B signaling |
| GO:0051496 | positive regulation of stress fiber assembly |
| GO:0072659 | protein localization to plasma membrane |
| GO:0097178 | ruffle assembly |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| PROSITE ID | PROSITE Term |
|---|---|
| PS51035 | BAG |
| Pfam ID | Pfam Term |
|---|---|
| PF02179 | BAG |