| Tag | Content |
|---|---|
| Uniprot ID | F1M3K6 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSRNOP00000061900 |
| Ensembl nucleotide ID | ENSRNOG00000042560 |
| Gene name | BCL2-associated athanogene 4 |
| Gene symbol | Bag4 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSALRRSGYG PSDGPSYGRY YGPGGGDVPV HVPPPLYHPL RPEPPQPPVS WRGRGGAPAE 60 TTWPGEGAGG DGYYPSGGAW AEPSRAGGGH QVSPVLPGFK LTYWAHVKSL AWLPNTLCLS 120 PTLQNKSLNS YANGAYGPPY PPGPATASAA SYSGAYYVPG YAQGTYSTDI PSTYRSPGNS 180 PTPVSRWMYP QQDCPTEAPP LRGQVPGYPA SQNPAMTLPH YPYGDGNRTV PQSGATGRPQ 240 DDAWASSAYG MGARYPWPSA APSAPSGNLY MTESASPWPG NSSPQPPPSP PPQQPKDSSY 300 SYSQSGQGMN RHSFPCSVRQ YESPGAVNND ESDLLDSQVQ YSAEPQLYGN TSSEHPSNQV 360 PSNNLPEECF SSDEGTPPSI KKIIHVLEKV QYLEQEVEEF GKKTDKAYWL LEEMLTKELL 420 ELDSVETGGQ DSVRQARKEA VCKIQAILEK LEKKGL 456 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | BAG4 | 516353 | F1MSS9 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | BAG4 | 607954 | E2R7V4 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | BAG4 | 102179734 | A0A452FDQ9 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | BAG4 | 100057730 | F6RTR6 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | BAG4 | 9530 | O95429 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Bag4 | 67384 | Q8CI61 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | BAG4 | H2QW14 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | BAG4 | A0A287AP23 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | BAG4 | 100353212 | G1T9D0 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Bag4 | F1M3K6 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | bag4 | 100001980 | B8JJ17 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005829 | cytosol |
| GO:0005634 | nucleus |
| GO:0005886 | plasma membrane |
| GO:0051087 | chaperone binding |
| GO:0031625 | ubiquitin protein ligase binding |
| GO:0071364 | cellular response to epidermal growth factor stimulus |
| GO:0071356 | cellular response to tumor necrosis factor |
| GO:2001145 | negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity |
| GO:1903215 | negative regulation of protein targeting to mitochondrion |
| GO:0030838 | positive regulation of actin filament polymerization |
| GO:0045785 | positive regulation of cell adhesion |
| GO:0010763 | positive regulation of fibroblast migration |
| GO:0033138 | positive regulation of peptidyl-serine phosphorylation |
| GO:0051897 | positive regulation of protein kinase B signaling |
| GO:0051496 | positive regulation of stress fiber assembly |
| GO:0072659 | protein localization to plasma membrane |
| GO:0097178 | ruffle assembly |
| PROSITE ID | PROSITE Term |
|---|---|
| PS51035 | BAG |
| Pfam ID | Pfam Term |
|---|---|
| PF02179 | BAG |