Gene: NUAK2

Basic information

Tag Content
Uniprot ID A0A287B415
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSSSCP00000051001
Ensembl nucleotide ID ENSSSCG00000038471
Gene name NUAK family kinase 2
Gene symbol NUAK2
Organism Sus scrofa
NCBI taxa ID 9823
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MESLAFPRRL GPGPSATAAL AAELVRPLAD GLLKSPKPLM KKQAVKRHHH KHNLRHRYEF 60
LETLGKGTYG KVKKARESSG RLVAIKSIRK DRIKDEQDLM HIRREIEIMS SLNHPHIIAI 120
HEVFENSSKI VIVMEYASRG DLYDYIIERQ RLSEREARHF FRQIVSAVHY CHQNGVVHRD 180
LKLENILLDA NGNIKIADFG LSNLYHQGKF LQTFCGSPLY ASPEIVNGKP YMGPEVDSWS 240
LGVLLYILVH GSMPFDGQDH KTLVKQISNG AYRQPPKPSD ACGLIRWLLM VNPTRRATLE 300
DVASHWWVNW GYATRVGEQE ALHEGGHPSS DSGRASMADW LRRSSRPLLE NGAKVCSFFK 360
QHAPGAGSLT PGLERQHSLK KSRKENDMAQ TLQGDPAADA SPRPGRGNLK LPKGILKKKA 420
STSSEGAREG PELSPVPAGP GQAAPLLPKK GILKKSRQRE SGYYSSPEPS ESGELLDAGD 480
VFVSGDAVEH KPPEASGLLL HRKGILKHNG KFSRAALELT APAFGSLDQL ASPGPPARAS 540
RPSGAVSEDS ILSSESFDQL DLPERLPEPP LRGCVSVDNL MGLEEPSSRA REAGA 595

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologNUAK2A0A452EIF1Capra hircusPredictionMore>>
1:1 orthologNUAK281788Q9H093Homo sapiensPredictionMore>>
1:1 orthologNuak274137Q8BZN4CPOMus musculusPublicationMore>>
1:1 orthologNUAK2457667H2Q0Z2Pan troglodytesPredictionMore>>
1:1 orthologNUAK2A0A287B415Sus scrofaPredictionMore>>
1:1 orthologNuak2289419Q66HE5Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005737 cytoplasm
GO:0016607 nuclear speck
GO:0005634 nucleus
GO:0005524 ATP binding
GO:0004674 protein serine/threonine kinase activity
GO:0035556 intracellular signal transduction
GO:0006468 protein phosphorylation

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS

PROSITE

PROSITE ID PROSITE Term
PS00107 PROTEIN_KINASE_ATP
PS50011 PROTEIN_KINASE_DOM
PS00108 PROTEIN_KINASE_ST

Pfam

Pfam ID Pfam Term
PF00069 Pkinase