Gene: NUAK2

Basic information

Tag Content
Uniprot ID A0A452EIF1
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSCHIP00000011820
Ensembl nucleotide ID ENSCHIG00000013817
Gene name Protein kinase domain-containing protein
Gene symbol NUAK2
Organism Capra hircus
NCBI taxa ID 9925
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MEPLPFPRRL GPAPSATALV RPLADGLLKS PKPLMKKQAV KRHHHKHNLR HRYEFLETLG 60
KGTYGKVKKA RESSGRLVAI KSIRKDKIKD EQDLMHIRRE IEIMSSLNHP HIIAIHEVFE 120
NSSRIVIVME YASRGDLYDY ISGRQRLSER EARHFFRQIV SAVHYCHQNG VVHRDLKLEN 180
ILLDANGNIK IADFGLSNLY HQGKFLQTFC GSPLYASPEI VNGKPYTGPE VDSWSLGVLL 240
YILVHGSMPF DGQDHKTLVK QISNGAYRQP PKPSDACGLI RWLLMVNPSR RATLEDVASH 300
WWVNWGYTTR VGEPGALNEG GHPSSDPGRT SVAQWLWRSS RPLLENGAKV CSFLKQQAPG 360
GRALAPGLER QHSLKKSRKE NAMAQTFQGA PATDASPRPG KGGLKLPKGI LKKKTSDPAE 420
GAAQGPEPGP SPANPGQAGP PLPKKGILKK AHQRESGYYS SPEPSESGEL LDAGDVFVSG 480
DTDHKPPPAS GRLPHRKGIL KHNGKFSHAA LEHTAPTTFG SLDELASPRP PARASHPSGA 540
VSEDSILSSE SFDQLDLPER LPEPPLRGSV SVDNLMGLEA PPLEGPGSRG LRRWRQDPLG 600
TSCFSLLDCP EGTEGGQQGL RVYSELS 627

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologNUAK2A0A452EIF1Capra hircusPredictionMore>>
1:1 orthologNUAK281788Q9H093Homo sapiensPredictionMore>>
1:1 orthologNuak274137Q8BZN4CPOMus musculusPublicationMore>>
1:1 orthologNUAK2457667H2Q0Z2Pan troglodytesPredictionMore>>
1:1 orthologNUAK2A0A287B415Sus scrofaPredictionMore>>
1:1 orthologNuak2289419Q66HE5Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005524 ATP binding
GO:0004672 protein kinase activity

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS

PROSITE

PROSITE ID PROSITE Term
PS00107 PROTEIN_KINASE_ATP
PS50011 PROTEIN_KINASE_DOM
PS00108 PROTEIN_KINASE_ST

Pfam

Pfam ID Pfam Term
PF00069 Pkinase