| Tag | Content |
|---|---|
| Uniprot ID | H2Q0Z2 |
| Entrez ID | 457667 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_003308709.3 |
| Ensembl protein ID | ENSPTRP00000003178 |
| Ensembl nucleotide ID | ENSPTRG00000001897 |
| Gene name | NUAK family kinase 2 |
| Gene symbol | NUAK2 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MLCFTARPGT AVAPRPGAGP VPRASALPAQ PIDSPAALAH LLLAMESLVF TRPSGPTPSA 60 AELARPLAEG LIKSPKPLMK KQAVKRHHHK HNLRHRYEFL ETLGKGTYGK VKKARESSGR 120 LVAIKSIRKD KIKDEQDLMH IRREIEIMSS LNHPHIIAIH EVFENSSKIV IVMEYASRGD 180 LYDYISERQQ LSEREARHFF RQIVSAVHYC HQNRVVHRDL KLENILLDAN GNIKIADFGL 240 SNLYHQGKFL QTFCGSPLYA SPEIVNGKPY TGPEVDSWSL GVLLYILVHG TMPFDGHDHK 300 ILVKQISNGA YREPPKPSDA CGLIRWLLMV NPTRRATLED VASHWWVNWG YATRVGEQEA 360 PHEGGHPGSD SVRASVADWL RRSSRPLLEN GAKVCSFFKQ HAPGGGSTTP GLERQHSLKK 420 SRKENDMAQS LHSDTADDTA HRPGKSNLKL PKGILKKKVS ASAEGAQEDP PELSPIPASP 480 GQAAPLLPKK GILKKPQQRE SGYYSSPEPS ESGELLDAGD VFVSGDPKEQ KPPQASGLLL 540 HRKGILKLNG KFSQTALELA APTTFGSLDE LAPSRPLARA SRPSGAVSED SILSSESFDQ 600 LDLPERLPEP PLRGCVSVDN LMGLEEPPSE GPGSCLRRWR QDPLGDSCFS LTDCQEVTAT 660 YRQALRVCSK LT 672 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | NUAK2 | A0A452EIF1 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | NUAK2 | 81788 | Q9H093 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Nuak2 | 74137 | Q8BZN4 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | NUAK2 | 457667 | H2Q0Z2 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | NUAK2 | A0A287B415 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Nuak2 | 289419 | Q66HE5 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0016607 | nuclear speck |
| GO:0005634 | nucleus |
| GO:0005524 | ATP binding |
| GO:0004674 | protein serine/threonine kinase activity |
| GO:0035556 | intracellular signal transduction |
| GO:0006468 | protein phosphorylation |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| Pfam ID | Pfam Term |
|---|---|
| PF00069 | Pkinase |