| Tag | Content |
|---|---|
| Uniprot ID | A0A287B8R5 |
| Entrez ID | |
| Genbank protein ID | HCZ83953.1 |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSSSCP00000052472 |
| Ensembl nucleotide ID | ENSSSCG00000003539 |
| Gene name | Grainyhead like transcription factor 3 |
| Gene symbol | GRHL3 |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSNELDFRSV RLLKNDPVNF QKFPYTTEDE AWKTYLENPL TAATKAMMRV NGDDDSVAAL 60 SFLYDYYMGP KEKRILSSST GGRNDQGKRY YHGMECEMDL TPLESPTHLM KFLTENVSGT 120 PEYPDVLKKS SLMSLEGAAP AAGKAALLPP GPSKLEAGSV DSYLLPTSDV YDNGSLSSLF 180 ESIHGVPPTQ RWQPDSTFKD DPQESLLFPD ILKTSQEPPC PEDYPSPKSD FEYTLGSPKA 240 IHIKSGESPM AYLNKGQFYP VTLRTPAGGK GLALSSNKVK SVVMVVFDNE KVPLEQLRFW 300 KHWHSRQPTA KQRVIDVADC KENFNTVQHI EEVAYNALSF VWNVNEEAKV FIGVNCLSTD 360 FSSQKGVKGV PLNLQIDTYD CGSGTERLVH RAVCQIKIFC DKGAERKMRD DERKQFRRKI 420 KCPDSSNSGI KGSLLSGFRG NETTYLRPEA DLETPPVLFI PNVHFSGLQR SGGAVLSAGH 480 SSSNRLPLKR TCSPFTEEFE PLPSKQAKED DLQRVLLYVR RETEEVFDAL MLKTPDLKGL 540 RNAISEKYGF PEENIHKVYK KCKRGILVNM DNNIIQHYSN HVAFLLDMGE LDGKIQIILK 600 EL 602 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | GRHL3 | 102178225 | A0A452F7N1 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | GRHL3 | 57822 | Q8TE85 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Grhl3 | 230824 | Q5FWH3 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | GRHL3 | 456630 | H2RDV8 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | GRHL3 | A0A287B8R5 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | GRHL3 | 100356381 | G1T595 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Grhl3 | 298555 | D4A1E5 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | grhl3 | E7F6C3 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005654 | nucleoplasm |
| GO:0005634 | nucleus |
| GO:0031490 | chromatin DNA binding |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO:0003700 | DNA-binding transcription factor activity |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0043565 | sequence-specific DNA binding |
| GO:0007417 | central nervous system development |
| GO:0090103 | cochlea morphogenesis |
| GO:0007398 | ectoderm development |
| GO:0008544 | epidermis development |
| GO:0001736 | establishment of planar polarity |
| GO:0061436 | establishment of skin barrier |
| GO:0061029 | eyelid development in camera-type eye |
| GO:0007389 | pattern specification process |
| GO:0090179 | planar cell polarity pathway involved in neural tube closure |
| GO:0043547 | positive regulation of GTPase activity |
| GO:0032956 | regulation of actin cytoskeleton organization |
| GO:0006357 | regulation of transcription by RNA polymerase II |
| GO:0042060 | wound healing |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| Pfam ID | Pfam Term |
|---|---|
| PF04516 | CP2 |