| Tag | Content |
|---|---|
| Uniprot ID | E7F6C3 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSDARP00000097661 |
| Ensembl nucleotide ID | ENSDARG00000078552 |
| Gene name | Grainyhead-like transcription factor 3 |
| Gene symbol | grhl3 |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MTKEIEALMV QQNESFSHIR TYESYVMDYW TNMDSGNLSK TKPRLASDED LATLNLLYDA 60 CKPSKEQKMT SCARESSIYK SMERTANSSS PELAPLENAH IMKFLSENMS FNPSKPSTDS 120 YTTDNYDKQV NLNNIFDSLL PQPSQKSWQS DQTFLEATPE HIGHNGFGGQ TSPVYSDSYS 180 SPGRYRNDFQ FLLGAPQASQ HKTTEIPMVY LNKGQFYPIT LQGVDSTAGV PCSKVKTVIM 240 AVFENDKSPE MQLKYWNHWH ARQPTVKQRV IDIADYKEVF SGVSNVEEVA FNALSFIWNT 300 NEEAKVHIGI NSLSTDFSSQ KGVKGLPLNL QIDTYDFSSG NNRLIHRAVC QVKIFCDKGA 360 ERKMRDEERK RSKRRTKNTA DSSNNNCKQA LVSSSVGKDS TYFKTLDDHV TQPVLFIPEM 420 HFSTMQRCGL VPPVSLEESD RSSLKRYADA NEQSSSPPCK QPRRDEQRVL LYVRRESEEV 480 FDALMLNTPN LKGLKEAISE KYGMQEDTIG KIFKKCKRGI FVNMDDNIIE HYSNHSAFLI 540 EISEVIVNHY QVTLMEL 557 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | GRHL3 | 102178225 | A0A452F7N1 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | GRHL3 | 57822 | Q8TE85 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Grhl3 | 230824 | Q5FWH3 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | GRHL3 | 456630 | H2RDV8 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | GRHL3 | A0A287B8R5 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | GRHL3 | 100356381 | G1T595 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Grhl3 | 298555 | D4A1E5 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | grhl3 | E7F6C3 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0003682 | chromatin binding |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0043565 | sequence-specific DNA binding |
| GO:0071466 | cellular response to xenobiotic stimulus |
| GO:0048703 | embryonic viscerocranium morphogenesis |
| GO:0090504 | epiboly |
| GO:0008544 | epidermis development |
| GO:0060325 | face morphogenesis |
| GO:0030917 | midbrain-hindbrain boundary development |
| GO:0001843 | neural tube closure |
| GO:0006357 | regulation of transcription by RNA polymerase II |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| InterPro ID | InterPro Term |
|---|---|
| IPR007604 | CP2 |
| Pfam ID | Pfam Term |
|---|---|
| PF04516 | CP2 |