| Tag | Content |
|---|---|
| Uniprot ID | A0A452F7N1 |
| Entrez ID | 102178225 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_005676846.3 |
| Ensembl protein ID | ENSCHIP00000020278 |
| Ensembl nucleotide ID | ENSCHIG00000018972 |
| Gene name | CP2 domain-containing protein |
| Gene symbol | GRHL3 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSNELDFRSV RLLKNDPVNF QKFPYTNEDE AWKTYLENPL TAATKAMMRV NGDDDSVAAL 60 SFLYDYYMGP KEKRLLSSST GGRNDQSKRY YHGMEYEMDL TPLESPTHLM KFLTENVSGT 120 PEYPDVLKKN NLMSVEGAAP TPGKAALLPA GPSKLETGSV DSYLLPTSDV YDNGSLSSLF 180 ENIHGVPPTQ RWQPDSTFKD DPQESLLFPD ILKTSPEPPG PEDYPKSDFE YTLGSPKAIH 240 IKSGESPMAY LNKGQFYPVT LRTPAGGKGL GLSSNKVKSV VMVVFDNEKG PVEQLRFWKH 300 WHSRQPTAKQ RVIDVADCKE NFNTVQHIEE VAYNALSFMW NVHEEAKVFV GVNCLSTDFS 360 SQKGVKGVPL NLQIDTYDCG SPSERLVHRA VCQIKIFCDK GAERKMRDDE RKQFRRKVKC 420 PDSSNSGIKG SLLAGFRGNE TTYLRPEADL ETPPVLFIPN VHFSSLQRPG GAVLSAGHSS 480 SNRLSLKRTC SPFTEEFEPL PSKQAKEDDL QRVLLYVRRE TEEVFDALML KTPDLKGLRS 540 AISEKYGFPE ENIYKVYKKC KRGILVNMDN NIIRHYSNHV AFLLDMGELD GKIQIILKEL 600 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | GRHL3 | 102178225 | A0A452F7N1 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | GRHL3 | 57822 | Q8TE85 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Grhl3 | 230824 | Q5FWH3 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | GRHL3 | 456630 | H2RDV8 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | GRHL3 | A0A287B8R5 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | GRHL3 | 100356381 | G1T595 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Grhl3 | 298555 | D4A1E5 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | grhl3 | E7F6C3 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005654 | nucleoplasm |
| GO:0031490 | chromatin DNA binding |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0007417 | central nervous system development |
| GO:0090103 | cochlea morphogenesis |
| GO:0007398 | ectoderm development |
| GO:0008544 | epidermis development |
| GO:0001736 | establishment of planar polarity |
| GO:0061436 | establishment of skin barrier |
| GO:0061029 | eyelid development in camera-type eye |
| GO:0007389 | pattern specification process |
| GO:0090179 | planar cell polarity pathway involved in neural tube closure |
| GO:0043547 | positive regulation of GTPase activity |
| GO:0032956 | regulation of actin cytoskeleton organization |
| GO:0042060 | wound healing |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| Pfam ID | Pfam Term |
|---|---|
| PF04516 | CP2 |