| Tag | Content |
|---|---|
| Uniprot ID | A0A287BDS9 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSSSCP00000054278 |
| Ensembl nucleotide ID | ENSSSCG00000037195 |
| Gene name | Forkhead box F2 |
| Gene symbol | FOXF2 |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MTSEGGPPPP PPRPPPAPLR RACSPAPGAL QAALMSPPPA AAAALEAASS SASASASASC 60 ASAGAPPAAC KSAGGGGGGA GAGGGGAKKA SSGLRRPEKP PYSYIALIVM AIQSSPAKRL 120 TLSEIYQFLQ ARFPFFRGAY QGWKNSVRHN LSLNECFIKL PKGLGRPGKG HYWTIDPASE 180 FMFEEGSFRR RPRGFRRKCQ ALKPMYHRVV SGLGFGASLL PQGFDFQAPP SAPLGCHAQG 240 GYGGLDMMPA GYDAGAGAPG HAHPHHHHHH VPHMSPNPGS TYMASCPVPA GPGGVGAAGG 300 GGGGDYGPDS SSSPVPSSPA MASAIECHSP YTSPAAHWSS PGASPYLKQP PALTPGSNPA 360 ASAGLHTSMS SYSLEQSYLH QNAREDLPVG LPRYQHHPAP VCDRKDFVLN FNGISSFHPS 420 ASGAYYHHHH HQSVCQDIKP CVM 443 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | FOXF2 | 106503520 | A0A452FDA0 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | FOXF2 | 2295 | Q12947 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Foxf2 | 14238 | O54743 | CPO | E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | FOXF2 | 750558 | H2R7P3 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | FOXF2 | A0A287BDS9 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | FOXF2 | G1TU67 | Oryctolagus cuniculus | Prediction | More>> | |||
| 1:1 ortholog | foxf2a | F1QHL6 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0005667 | transcription factor complex |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding |
| GO:0008134 | transcription factor binding |
| GO:0048596 | embryonic camera-type eye morphogenesis |
| GO:0048566 | embryonic digestive tract development |
| GO:0042249 | establishment of planar polarity of embryonic epithelium |
| GO:0030198 | extracellular matrix organization |
| GO:0048806 | genitalia development |
| GO:0045892 | negative regulation of transcription, DNA-templated |
| GO:0032434 | regulation of proteasomal ubiquitin-dependent protein catabolic process |
| GO:1902914 | regulation of protein polyubiquitination |
| GO:0060021 | roof of mouth development |
| Pfam ID | Pfam Term |
|---|---|
| PF00250 | Forkhead |