| Tag | Content |
|---|---|
| Uniprot ID | A0A452FDA0 |
| Entrez ID | 106503520 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018039309.1 |
| Ensembl protein ID | ENSCHIP00000022344 |
| Ensembl nucleotide ID | ENSCHIG00000020355 |
| Gene name | Fork-head domain-containing protein |
| Gene symbol | FOXF2 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MTSEGGPPPP PPRPPPAPLR RARSPGPGAL QAALMSPPPA AAAALEAASS SSSSSSAASS 60 AGAAPNACKS AGGGAGAGGG GAKKASAGLR RPEKPPFSYI ALIVMAIQSS PAKRLTLSEI 120 YQFLQARFPF FRGAYQGWKN SVRHNLSLNE CFIKLPKGLG RPGKGHYWTI DPASEFMFEE 180 GSFRRRPRGF RRKCQALKPM YHRVVSGLGF GASLLPQGFD FQAPPSAPLG CHGQGGYGGL 240 DMMPAGYDAG AGAPGHAHPH HRHHHVPHMS PNPGSTYMAS CPVPAGPGAV GAAGGGGGGD 300 YGPDSSSSPV PSSPAVASAI ECHSPYTSPA AHWSSPGASP YLKQPPALTP GSTPAAPAGL 360 HSTMSSYSLE QSYLHQNARE DLPVALPRYQ HHSTPVCDRK DFVLNFNGIS SFHPSASGPY 420 YHHHHQSVCQ DIKPCVM 437 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | FOXF2 | 106503520 | A0A452FDA0 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | FOXF2 | 2295 | Q12947 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Foxf2 | 14238 | O54743 | CPO | E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | FOXF2 | 750558 | H2R7P3 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | FOXF2 | A0A287BDS9 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | FOXF2 | G1TU67 | Oryctolagus cuniculus | Prediction | More>> | |||
| 1:1 ortholog | foxf2a | F1QHL6 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0005667 | transcription factor complex |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding |
| GO:0008134 | transcription factor binding |
| GO:0048596 | embryonic camera-type eye morphogenesis |
| GO:0048566 | embryonic digestive tract development |
| GO:0042249 | establishment of planar polarity of embryonic epithelium |
| GO:0030198 | extracellular matrix organization |
| GO:0048806 | genitalia development |
| GO:0045892 | negative regulation of transcription, DNA-templated |
| GO:0032434 | regulation of proteasomal ubiquitin-dependent protein catabolic process |
| GO:1902914 | regulation of protein polyubiquitination |
| GO:0060021 | roof of mouth development |
| Pfam ID | Pfam Term |
|---|---|
| PF00250 | Forkhead |