Gene: FOXF2

Basic information

Tag Content
Uniprot ID G1TU67
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSOCUP00000020591
Ensembl nucleotide ID ENSOCUG00000013970
Gene name Forkhead box F2
Gene symbol FOXF2
Organism Oryctolagus cuniculus
NCBI taxa ID 9986
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MTTEGGPPPP PPRPPPAPLR RACSPAPGAL QAALMSAPAA AALETAATSS SSSSSSSSSS 60
SSSSSNSAGA SSAACKSSSG GGGAGAGSGG PKKASSGLRR PEKPPYSYIA LIVMAIQSSP 120
SKRLTLSEIY QFLQARFPFF RGAYQGWKNS VRHNLSLNEC FIKLPKGLGR PGKGHYWTID 180
PASEFMFEEG SFRRRPRGFR RKCQALKPMY HRVVSGLGFG ASLLPQGFDF QAPPSAPLGC 240
HGQGGYGGLD MMATGYDAGA GAPGHAHPHH HHHHHVPHMS PNPGSTYMAS CPVPAGPGAV 300
GAAGGVGGGG GSGGGGDYGP DSSSSPVPSS PAMASAIECH SPYTSPAAHW SSPGASPYLK 360
QPPALTPSGN PAGAAGLHAS MSSYSLEQSY LHQNAREDLS VGLPRYQPHS TPVCDRKDFV 420
LNFNGISSFH PSAQRVILFT TTTRACARTS SPASCETTGG PVWTSSPAFM SVWWPPHRQG 480
ADGKRSPLSS AARGGRERRG LALAVSSPKP QPECPGELGR

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologFOXF2106503520A0A452FDA0Capra hircusPredictionMore>>
1:1 orthologFOXF22295Q12947Homo sapiensPublicationMore>>
1:1 orthologFoxf214238O54743CPOE14.5Mus musculusPublicationMore>>
1:1 orthologFOXF2750558H2R7P3Pan troglodytesPredictionMore>>
1:1 orthologFOXF2A0A287BDS9Sus scrofaPredictionMore>>
1:1 orthologFOXF2G1TU67Oryctolagus cuniculusPredictionMore>>
1:1 orthologfoxf2aF1QHL6Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0005667 transcription factor complex
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding
GO:0008134 transcription factor binding
GO:0048806 genitalia development
GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:1902914 regulation of protein polyubiquitination
GO:0060021 roof of mouth development

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0238 DNA-binding
KW-0539 Nucleus
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR001766 Fork_head_dom
IPR018122 TF_fork_head_CS_1
IPR030456 TF_fork_head_CS_2
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf

PROSITE

PROSITE ID PROSITE Term
PS00657 FORK_HEAD_1
PS00658 FORK_HEAD_2
PS50039 FORK_HEAD_3

Pfam

Pfam ID Pfam Term
PF00250 Forkhead