| Tag | Content |
|---|---|
| Uniprot ID | O54743; B2RQI5; Q3V1L3; Q78DW1; |
| Entrez ID | 14238 |
| Genbank protein ID | AAI37948.1; AAI37950.1; CAA72972.1; BAE21137.1; CAA72035.1; |
| Genbank nucleotide ID | NM_010225.2 |
| Ensembl protein ID | ENSMUSP00000046789 |
| Ensembl nucleotide ID | ENSMUSG00000038402 |
| Gene name | Forkhead box protein F2 |
| Gene symbol | Foxf2 |
| Organism | Mus musculus |
| NCBI taxa ID | 10090 |
| Cleft type | CPO |
| Developmental stage | E14.5 |
| Data sources | Manually collected |
| Reference | 12812790 |
| Functional description | Probable transcription activator for a number of lung-specific genes (PubMed:9676429). Mediates up-regulation of the E3 ligase IRF2BPL and drives ubiquitination and degradation of CTNNB1 (By similarity). |
| Sequence | MSTEGGPPPP PPRPPPAPLR RACSPAPGAL QAALMSPPPA ATLESTSSSS SSSSASCASS 60 SSNSVSASAG ACKSAASSGG AGAGSGGTKK ATSGLRRPEK PPYSYIALIV MAIQSSPSKR 120 LTLSEIYQFL QARFPFFRGA YQGWKNSVRH NLSLNECFIK LPKGLGRPGK GHYWTIDPAS 180 EFMFEEGSFR RRPRGFRRKC QALKPMYHRV VSGLGFGASL LPQGFDFQAP PSAPLGCHGQ 240 GGYGGLDMMP AGYDTGAGAP GHAHPHHLHH HHVPHMSPNP GSTYMASCPV PAGPAGVGAA 300 AGGGGGGGDY GPDSSSSPVP SSPAMASAIE CHSPYTSPAA HWSSPGASPY LKQPPALTPS 360 SNPAASAGLH PSMSSYSLEQ SYLHQNARED LSVGLPRYQH HSTPVCDRKD FVLNFNGISS 420 FHPSASGSYY HHHHQSVCQD IKPCVM 446 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
