| Tag | Content |
|---|---|
| Uniprot ID | H2R7P3; A0A2J8MU48; |
| Entrez ID | 750558 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_001174677.4 |
| Ensembl protein ID | ENSPTRP00000050645 |
| Ensembl nucleotide ID | ENSPTRG00000017662 |
| Gene name | Forkhead box F2 |
| Gene symbol | FOXF2 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MTTEGGPPPA PLRRACSPVP GALQAALMSP PPAAAAAALE TTSSSSSSSS ASCASSSSSS 60 NSASAPSAAC KSTGGGGAGA GSGGAKKASS GLRRPEKPPY SYIALIVMAI QSSPSKRLTL 120 SEIYQFLQAR FPFFRGAYQG WKNSVRHNLS LNECFIKLPK GLGRPGKGHY WTIDPASEFM 180 FEEGSFRRRP RGFRRKCQAL KPMYHRVVSG LGFGASLLPQ GFDFQAPPSA PLGCHSQGGY 240 GGLDMMPAGY DAGAGAPSHA HPHHHHHHHV PHMSPNPGST YMASCPVPAG PGGVGAAGGG 300 GGGGGGDYGP DSSSSPVPSS PAMASAIECH SPYTSPAAHW SSPGASPYLK QPPALTPSSN 360 PAASAGLHSS MSSYSLEQSY LHQNAREDLS VGLPRYQHHS TPVCDRKDFV LNFNGISSFH 420 PSASGSYYHH HHQSVCQDIK PCVM 444 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | FOXF2 | 106503520 | A0A452FDA0 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | FOXF2 | 2295 | Q12947 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Foxf2 | 14238 | O54743 | CPO | E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | FOXF2 | 750558 | H2R7P3 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | FOXF2 | A0A287BDS9 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | FOXF2 | G1TU67 | Oryctolagus cuniculus | Prediction | More>> | |||
| 1:1 ortholog | foxf2a | F1QHL6 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0005667 | transcription factor complex |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding |
| GO:0008134 | transcription factor binding |
| GO:0048596 | embryonic camera-type eye morphogenesis |
| GO:0048566 | embryonic digestive tract development |
| GO:0042249 | establishment of planar polarity of embryonic epithelium |
| GO:0030198 | extracellular matrix organization |
| GO:0048806 | genitalia development |
| GO:0045892 | negative regulation of transcription, DNA-templated |
| GO:0032434 | regulation of proteasomal ubiquitin-dependent protein catabolic process |
| GO:1902914 | regulation of protein polyubiquitination |
| GO:0060021 | roof of mouth development |
| Pfam ID | Pfam Term |
|---|---|
| PF00250 | Forkhead |