Gene: PBX1

Basic information

Tag Content
Uniprot ID A0A2I3RPY9
Entrez ID 457474
Genbank protein ID
Genbank nucleotide ID XM_009436875.2
Ensembl protein ID ENSPTRP00000066720
Ensembl nucleotide ID ENSPTRG00000001611
Gene name PBX homeobox 1
Gene symbol PBX1
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MDEQPRLMHS HAGVGMAGHP GLSQHLQDGA GGTEGEGGRK QDIGDILQQI MTITDQSLDE 60
AQARKHALNC HRMKPALFNV LCEIKEKTEL KEARSRNCPS LFFLVTRIQS SVRHRVLSSA 120
STSGNPVTPQ PTHHHPSFGW GEGKVLSIRG AQEEEPTDPQ LMRLDNMLLA EGVAGPEKGG 180
GSAAAAAAAA ASGGAGSDNS VEHSDYRAKL SQIRQIYHTE LEKYEQACNE FTTHVMNLLR 240
EQSRTRPISP KEIERMVSII HRKFSSIQMQ LKQSTCEAVM ILRSRFLDAR RKRRNFNKQA 300
TEILNEYFYS HLSNPYPSEE AKEELAKKCG ITVSQVSNWF GNKRIRYKKN IGKFQEEANI 360
YAAKTAVTAT NVSAHGSQAN SPSTPNSAGS SSSFNMSNSG DLFMSVQSLN GDSYQGAQVG 420
ANVQSQVDTL RHVISQTGGY SDGLAASQMY SPQGISEIAR TY 462

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologPBX1F1PDM8Canis lupus familiarisPredictionMore>>
1:1 orthologPBX1A0A452FB79Capra hircusPredictionMore>>
1:1 orthologPBX15087P40424Homo sapiensPredictionMore>>
1:1 orthologPbx118514P41778CPO,CLP,CLOE13.5Mus musculusPublicationMore>>
1:1 orthologPBX1457474A0A2I3RPY9Pan troglodytesPredictionMore>>
1:1 orthologPbx1D3ZJI6Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0175 Coiled coil
KW-0238 DNA-binding
KW-0371 Homeobox
KW-0539 Nucleus
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR005542 PBX

PROSITE

PROSITE ID PROSITE Term
PS00027 HOMEOBOX_1
PS50071 HOMEOBOX_2

Pfam

Pfam ID Pfam Term
PF00046 Homeodomain
PF03792 PBC