Tag | Content |
---|---|
Uniprot ID | D3ZJI6 |
Entrez ID | |
Genbank protein ID | |
Genbank nucleotide ID | |
Ensembl protein ID | ENSRNOP00000039416 |
Ensembl nucleotide ID | ENSRNOG00000004693 |
Gene name | PBX homeobox 1 |
Gene symbol | Pbx1 |
Organism | Rattus norvegicus |
NCBI taxa ID | 10116 |
Cleft type | |
Developmental stage | |
Data sources | Homology search |
Reference | |
Functional description | |
Sequence | VLSIRGAQEE EPTDPQLMRL DNMLLAEGVA GPEKGGGSAA AAAAAAASGG AGSDNSVEHS 60 DYRAKLSQIR QIYHTELEKY EQACNEFTTH VMNLLREQSR TRPISPKEIE RMVSIIHRKF 120 SSIQMQLKQS TCEAVMILRS RFLDARRKRR NFNKQATEIL NEYFYSHLSN PYPSEEAKEE 180 LAKKCGITVS QVSNWFGNKR IRYKKNIGKF QEEANIYAAK TAVTATNVSA HGSQANSPST 240 PNSAGSSSSF NMSNSGDLFM SVQSLNGDSY QGAQVGANVQ SQVDTLRHVI SQTGGYSDGL 300 AASQMYSPQG ISANGGWQDA TTPSSVTSPT EGPGSVHSDT SN 342 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
---|---|---|---|---|---|---|---|---|
1:1 ortholog | PBX1 | F1PDM8 | Canis lupus familiaris | Prediction | More>> | |||
1:1 ortholog | PBX1 | A0A452FB79 | Capra hircus | Prediction | More>> | |||
1:1 ortholog | PBX1 | 5087 | P40424 | Homo sapiens | Prediction | More>> | ||
1:1 ortholog | Pbx1 | 18514 | P41778 | CPO,CLP,CLO | E13.5 | Mus musculus | Publication | More>> |
1:1 ortholog | PBX1 | 457474 | A0A2I3RPY9 | Pan troglodytes | Prediction | More>> | ||
1:1 ortholog | Pbx1 | D3ZJI6 | Rattus norvegicus | Prediction | More>> |
GO ID | GO Term |
---|---|
GO:0005737 | cytoplasm |
GO:0005654 | nucleoplasm |
GO:0005634 | nucleus |
GO:0090575 | RNA polymerase II transcription factor complex |
GO:0005667 | transcription factor complex |
GO:0003677 | DNA binding |
GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
GO:0046982 | protein heterodimerization activity |
GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO:0043565 | sequence-specific DNA binding |
GO:0008134 | transcription factor binding |
GO:0030325 | adrenal gland development |
GO:0009887 | animal organ morphogenesis |
GO:0009952 | anterior/posterior pattern specification |
GO:0001658 | branching involved in ureteric bud morphogenesis |
GO:0035162 | embryonic hemopoiesis |
GO:0030326 | embryonic limb morphogenesis |
GO:0048568 | embryonic organ development |
GO:0048706 | embryonic skeletal system development |
GO:0043433 | negative regulation of DNA-binding transcription factor activity |
GO:0045665 | negative regulation of neuron differentiation |
GO:0008284 | positive regulation of cell population proliferation |
GO:0010971 | positive regulation of G2/M transition of mitotic cell cycle |
GO:0045944 | positive regulation of transcription by RNA polymerase II |
GO:0009954 | proximal/distal pattern formation |
GO:0042127 | regulation of cell population proliferation |
GO:0030278 | regulation of ossification |
GO:0048536 | spleen development |
GO:0048538 | thymus development |
GO:0001655 | urogenital system development |