| Tag | Content |
|---|---|
| Uniprot ID | A0A452FB79 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSCHIP00000021441 |
| Ensembl nucleotide ID | ENSCHIG00000019761 |
| Gene name | Homeobox domain-containing protein |
| Gene symbol | PBX1 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MRLDNMLLAE GVAGPEKGGG SAAAAAAAAA SGGAGSDNSV EHSDYRAKLS QIRQIYHTEL 60 EKYEQACNEF TTHVMNLLRE QSRTRPISPK EIERMVSIIH RKFSSIQMQL KQSTCEAVMI 120 LRSRFLDARR KRRNFNKQAT EILNEYFYSH LSNPYPSEEA KEELAKKCGI TVSQVSNWFG 180 NKRIRYKKNI GKFQEEANIY AAKTAVTATN VSAHGSQANS PSTPNSAGSS SSFNMSNSGD 240 LFMSVQSLNG DSYQGAQVGA NVQSQVDTLR HVISQTGGYS DGLAASQMYS PQGISANGGW 300 QDATTPSSVT SPTEGPGSVH SDTSN 325 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PBX1 | F1PDM8 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | PBX1 | A0A452FB79 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | PBX1 | 5087 | P40424 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Pbx1 | 18514 | P41778 | CPO,CLP,CLO | E13.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | PBX1 | 457474 | A0A2I3RPY9 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Pbx1 | D3ZJI6 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0005654 | nucleoplasm |
| GO:0090575 | RNA polymerase II transcription factor complex |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0030325 | adrenal gland development |
| GO:0009952 | anterior/posterior pattern specification |
| GO:0001658 | branching involved in ureteric bud morphogenesis |
| GO:0035162 | embryonic hemopoiesis |
| GO:0030326 | embryonic limb morphogenesis |
| GO:0048706 | embryonic skeletal system development |
| GO:0045665 | negative regulation of neuron differentiation |
| GO:0008284 | positive regulation of cell population proliferation |
| GO:0010971 | positive regulation of G2/M transition of mitotic cell cycle |
| GO:0009954 | proximal/distal pattern formation |
| GO:0030278 | regulation of ossification |
| GO:0048536 | spleen development |
| GO:0048538 | thymus development |