| Tag | Content |
|---|---|
| Uniprot ID | F1PDM8 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_545786.5 |
| Ensembl protein ID | ENSCAFP00000019606 |
| Ensembl nucleotide ID | ENSCAFG00000013289 |
| Gene name | PBX homeobox 1 |
| Gene symbol | PBX1 |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MDEQPRLMHS HAGVGMAGHP GLSQHLQDGA GGTEGEGGRK QDIGDILQQI MTITDQSLDE 60 AQARKHALNC HRMKPALFNV LCEIKEKTVL SIRGAQEEEP TDPQLMRLDN MLLAEGVAGP 120 EKGGGSAAAA AAAAASGGAG SDNSVEHSDY RAKLSQIRQI YHTELEKYEQ ACNEFTTHVM 180 NLLREQSRTR PISPKEIERM VSIIHRKFSS IQMQLKQSTC EAVMILRSRF LDARRKRRNF 240 NKQATEILNE YFYSHLSNPY PSEEAKEELA KKCGITVSQV SNWFGNKRIR YKKNIGKFQE 300 EANIYAAKTA VTATNVSAHG SQANSPSTPN SAGSSSSFNM SNSGDLFMGV QSLNGDSYQG 360 AQVGANVQSQ VDTLRHVISQ TGGYSDGLAA SQMYSPQGIS ANGGWQDATT PSSVTSPTEG 420 PGSVHSDTSN |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PBX1 | F1PDM8 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | PBX1 | A0A452FB79 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | PBX1 | 5087 | P40424 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Pbx1 | 18514 | P41778 | CPO,CLP,CLO | E13.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | PBX1 | 457474 | A0A2I3RPY9 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Pbx1 | D3ZJI6 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0005654 | nucleoplasm |
| GO:0090575 | RNA polymerase II transcription factor complex |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0030325 | adrenal gland development |
| GO:0009952 | anterior/posterior pattern specification |
| GO:0001658 | branching involved in ureteric bud morphogenesis |
| GO:0035162 | embryonic hemopoiesis |
| GO:0030326 | embryonic limb morphogenesis |
| GO:0048706 | embryonic skeletal system development |
| GO:0045665 | negative regulation of neuron differentiation |
| GO:0008284 | positive regulation of cell population proliferation |
| GO:0010971 | positive regulation of G2/M transition of mitotic cell cycle |
| GO:0009954 | proximal/distal pattern formation |
| GO:0030278 | regulation of ossification |
| GO:0048536 | spleen development |
| GO:0048538 | thymus development |