| Tag | Content |
|---|---|
| Uniprot ID | A0A2I3RUL7 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSPTRP00000068017 |
| Ensembl nucleotide ID | ENSPTRG00000019369 |
| Gene name | ATP binding cassette subfamily B member 1 |
| Gene symbol | ABCB1 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MDLEGDRNGG FRYSNWLDKL YMVVGTLAAI IHGAGLPLMM LVFGEMTDIF ANAGNLEDLM 60 SNITNRSDIN DTGFFMNLEE DMTRYAYYYS GIGAGVLVAA YIQVSFWCLA AGRQIHKIRK 120 QFFHAIMRQE IGWFDVHDVG ELNTRLTDDV SKINEGIGDK IGMFFQSMAT FFTGFIVGFT 180 RGWKLTLVIL AISPVLGLSA AVWAKILSSF TDKELLAYAK AGAVAEEVLA AIRTVIAFGG 240 QKKELERYNK NLEEAKRIGI KKAITANISI GAAFLLIYAS YALAFWYGTT LVLSGEYSIG 300 QVLTVFFSVL IGAFSVGQAS PSIEAFANAR GAAYEIFKII DNKPSIDSYS KSGHKPDNIK 360 GNLEFRNVHF SYPSRKQVKI LKGLNLKVQS GQTVALVGNS GCGKSTTVQL MQRLYDPTEG 420 MVSVDGQDIR TINVRFLREI IGVVSQEPVL FATTIAENIR YGRENVTMDE IEKAVKEANA 480 YDFIMKLPHK FDTLVGERGA QLSGGQKQRI AIARALVRNP KILLLDEATS ALDTESEAVV 540 QVALDKARKG RTTIVIAHRL STVRNADVIA GFDDGVIVEK GNHDELMKEK GIYFKLVTMQ 600 TAGNEVELEN AADESKSEID ALEMSSNDSR SSLIRKRSTR RSVRGSQAQD RKLSTKEALD 660 ESIPPVSFWR IMKLNLTEWP YFVVGVFCAI INGGLQPAFA IIFSKIIGVF TRIDDPETKR 720 QNSNLFSLLF LVLGIISFIT FFLQGFTFGK AGEILTKRLR YMVFRSMLRQ DVSWFDDPKN 780 TTGALTTRLA NDAAQVKGAI GSRLAVITQN IANLGTGIII SFIYGWQLTL LLLAIVPIIA 840 IAGVVEMKML SGQALKDKKE LEGAGKIASE AIENFRTVVS LTQEQKFEHM YAQSLQVPYR 900 NSLRKAHIFG ITFSFTQAMM YFSYAGCFRF GAYLVAHKLM SFEDVLLVFS AVVFGAMAVG 960 QVSSFAPDYA KAKISAAHII MIIEKTPLID SYSTEGLTPN TLEGNVTFGE VVFNYPTRPD 1020 IPVLQGLSLE VKKGQTLALV GSSGCGKSTV VQLLERFYDP LAGKVLLDGK EIKRLNVQWL 1080 RAHLGIVSQE PILFDCSIAE NIAYGDNSRV VSQEEIVRAA KEANIHAFIE SLPNKYSTRV 1140 GDKGTQLSGG QKQRIAIARA LVRQPHILLL DEATSALDTE SEKVVQEALD KAREGRTCIV 1200 IAHRLSTIQN ADLIVVFQNG RVKEHGTHQQ LLAQKGIYFS MVSVQAGTKR Q 1251 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ABCB1 | 403879 | Q4PLA8 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | ABCB1 | 5243 | P08183 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Abcb1a | 18671 | P21447 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | ABCB1 | A0A2I3RUL7 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | ABCB1 | 100008914 | G1T8H8 | Oryctolagus cuniculus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0005524 | ATP binding |
| GO:0016887 | ATPase activity |
| GO:0042626 | ATPase-coupled transmembrane transporter activity |