CleftGeneDB-Search

Gene: ABCB1

Basic information

Tag	Content
Uniprot ID	P08183; A8K294; B5AK60; Q12755; Q14812;
Entrez ID	5243
Genbank protein ID	AAA88047.1; AAA59575.1; BAF82848.1; AAB69423.1; CAA41558.1; AAA59576.1; AAM49149.1; AAA88048.1; AAW82430.1; ACF94688.1;
Genbank nucleotide ID	NM_000927.4
Ensembl protein ID	ENSP00000444095; ENSP00000478255; ENSP00000265724;
Ensembl nucleotide ID	ENSG00000085563
Gene name	ATP-dependent translocase ABCB1
Gene symbol	ABCB1
Organism	Homo sapiens
NCBI taxa ID	9606
Cleft type
Developmental stage
Data sources	Manually collected
Reference	19760622; 23443032;
Functional description	Translocates drugs and phospholipids across the membrane (PubMed:8898203, PubMed:2897240, PubMed:9038218). Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins (PubMed:8898203). Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells (PubMed:2897240, PubMed:9038218).
Sequence	MDLEGDRNGG AKKKNFFKLN NKSEKDKKEK KPTVSVFSMF RYSNWLDKLY MVVGTLAAII 60 HGAGLPLMML VFGEMTDIFA NAGNLEDLMS NITNRSDIND TGFFMNLEED MTRYAYYYSG 120 IGAGVLVAAY IQVSFWCLAA GRQIHKIRKQ FFHAIMRQEI GWFDVHDVGE LNTRLTDDVS 180 KINEGIGDKI GMFFQSMATF FTGFIVGFTR GWKLTLVILA ISPVLGLSAA VWAKILSSFT 240 DKELLAYAKA GAVAEEVLAA IRTVIAFGGQ KKELERYNKN LEEAKRIGIK KAITANISIG 300 AAFLLIYASY ALAFWYGTTL VLSGEYSIGQ VLTVFFSVLI GAFSVGQASP SIEAFANARG 360 AAYEIFKIID NKPSIDSYSK SGHKPDNIKG NLEFRNVHFS YPSRKEVKIL KGLNLKVQSG 420 QTVALVGNSG CGKSTTVQLM QRLYDPTEGM VSVDGQDIRT INVRFLREII GVVSQEPVLF 480 ATTIAENIRY GRENVTMDEI EKAVKEANAY DFIMKLPHKF DTLVGERGAQ LSGGQKQRIA 540 IARALVRNPK ILLLDEATSA LDTESEAVVQ VALDKARKGR TTIVIAHRLS TVRNADVIAG 600 FDDGVIVEKG NHDELMKEKG IYFKLVTMQT AGNEVELENA ADESKSEIDA LEMSSNDSRS 660 SLIRKRSTRR SVRGSQAQDR KLSTKEALDE SIPPVSFWRI MKLNLTEWPY FVVGVFCAII 720 NGGLQPAFAI IFSKIIGVFT RIDDPETKRQ NSNLFSLLFL ALGIISFITF FLQGFTFGKA 780 GEILTKRLRY MVFRSMLRQD VSWFDDPKNT TGALTTRLAN DAAQVKGAIG SRLAVITQNI 840 ANLGTGIIIS FIYGWQLTLL LLAIVPIIAI AGVVEMKMLS GQALKDKKEL EGSGKIATEA 900 IENFRTVVSL TQEQKFEHMY AQSLQVPYRN SLRKAHIFGI TFSFTQAMMY FSYAGCFRFG 960 AYLVAHKLMS FEDVLLVFSA VVFGAMAVGQ VSSFAPDYAK AKISAAHIIM IIEKTPLIDS 1020 YSTEGLMPNT LEGNVTFGEV VFNYPTRPDI PVLQGLSLEV KKGQTLALVG SSGCGKSTVV 1080 QLLERFYDPL AGKVLLDGKE IKRLNVQWLR AHLGIVSQEP ILFDCSIAEN IAYGDNSRVV 1140 SQEEIVRAAK EANIHAFIES LPNKYSTKVG DKGTQLSGGQ KQRIAIARAL VRQPHILLLD 1200 EATSALDTES EKVVQEALDK AREGRTCIVI AHRLSTIQNA DLIVVFQNGR VKEHGTHQQL 1260 LAQKGIYFSM VSVQAGTKRQ

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Gene expression information

Gene expression in different tissues (GTEx V7)

Gene expression in different tissues (ENCODE)

Protein structural annotations

3D structure in PDB database

PDB ID
6C0V
6FN1
6FN4
6QEX

Protein disorder information

Orthologous information

Relation	Gene symbol	Entrez ID	UniProt ID	Species	Evidence	Details
1:1 ortholog	ABCB1	403879	Q4PLA8	Canis lupus familiaris	Prediction	More>>
1:1 ortholog	ABCB1	5243	P08183	Homo sapiens	Publication	More>>
1:1 ortholog	Abcb1a	18671	P21447	Mus musculus	Prediction	More>>
1:1 ortholog	ABCB1		A0A2I3RUL7	Pan troglodytes	Prediction	More>>
1:1 ortholog	ABCB1	100008914	G1T8H8	Oryctolagus cuniculus	Prediction	More>>

Identified variants/mutations related to cleft phenotype

Gene symbol	Significant Variants/SNPS	Methods	PubMed ID
ABCB1	rs1128503	PCR; TaqMan genotyping	23443032
ABCB1	rs1045642	RFLP	19760622

Other genetic variants/mutations

ID	Variant	Type	Disease	Chromosome\Coordinate	Evidence
rs1320562631	p.Asp2Asn	missense variant	-	NC_000007.14:g.87600181C>T	gnomAD
rs747238624	p.Gly5Val	missense variant	-	NC_000007.14:g.87600171C>A	ExAC,TOPMed,gnomAD
rs780204251	p.Asp6His	missense variant	-	NC_000007.14:g.87600169C>G	ExAC,gnomAD
rs780204251	p.Asp6Tyr	missense variant	-	NC_000007.14:g.87600169C>A	ExAC,gnomAD
rs1429920034	p.Arg7His	missense variant	-	NC_000007.14:g.87600165C>T	TOPMed
rs758755760	p.Arg7Cys	missense variant	-	NC_000007.14:g.87600166G>A	ExAC,TOPMed,gnomAD
rs758755760	p.Arg7Gly	missense variant	-	NC_000007.14:g.87600166G>C	ExAC,TOPMed,gnomAD
rs146259092	p.Asn8Lys	missense variant	-	NC_000007.14:g.87600161A>C	ESP,ExAC,TOPMed,gnomAD
rs1373721748	p.Asn8Thr	missense variant	-	NC_000007.14:g.87600162T>G	gnomAD
rs1457629148	p.Gly10Arg	missense variant	-	NC_000007.14:g.87600157C>T	gnomAD
rs1348388210	p.Gly10Glu	missense variant	-	NC_000007.14:g.87600156C>T	gnomAD
NCI-TCGA novel	p.Lys12Asn	missense variant	-	NC_000007.14:g.87600149C>A	NCI-TCGA
rs1430496324	p.Lys12Asn	missense variant	-	NC_000007.14:g.87600149C>G	gnomAD
rs779268249	p.Lys12Gln	missense variant	-	NC_000007.14:g.87600151T>G	ExAC,TOPMed,gnomAD
rs1390637727	p.Lys14Asn	missense variant	-	NC_000007.14:g.87600143C>A	gnomAD
NCI-TCGA novel	p.Lys14Glu	missense variant	-	NC_000007.14:g.87600145T>C	NCI-TCGA
NCI-TCGA novel	p.Phe16Leu	missense variant	-	NC_000007.14:g.87600137A>C	NCI-TCGA
rs28381804	p.Phe17Leu	missense variant	-	NC_000007.14:g.87600136A>G	1000Genomes,ExAC,TOPMed,gnomAD
rs763540261	p.Phe17Ser	missense variant	-	NC_000007.14:g.87600135A>G	ExAC,gnomAD
rs760162850	p.Phe17Leu	missense variant	-	NC_000007.14:g.87600134A>T	ExAC,TOPMed,gnomAD
rs41304191	p.Leu19Val	missense variant	-	NC_000007.14:g.87600130G>C	ExAC,TOPMed,gnomAD
rs200915526	p.Leu19Gln	missense variant	-	NC_000007.14:g.87600129A>T	1000Genomes,ExAC,gnomAD
rs9282564	p.Asn21His	missense variant	-	NC_000007.14:g.87600124T>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs9282564	p.Asn21Asp	missense variant	-	NC_000007.14:g.87600124T>C	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs9282564	p.Asn21Tyr	missense variant	-	NC_000007.14:g.87600124T>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs754610572	p.Asp26Val	missense variant	-	NC_000007.14:g.87595806T>A	ExAC
rs1424498745	p.Lys27Glu	missense variant	-	NC_000007.14:g.87595804T>C	TOPMed
rs1202446124	p.Lys27Thr	missense variant	-	NC_000007.14:g.87595803T>G	gnomAD
rs112801674	p.Lys28Arg	missense variant	-	NC_000007.14:g.87595800T>C	TOPMed
rs112801674	p.Lys28Thr	missense variant	-	NC_000007.14:g.87595800T>G	TOPMed
NCI-TCGA novel	p.Lys30Asn	missense variant	-	NC_000007.14:g.87595793C>A	NCI-TCGA
rs1257107888	p.Pro32Arg	missense variant	-	NC_000007.14:g.87595788G>C	gnomAD
NCI-TCGA novel	p.Pro32Gln	missense variant	-	NC_000007.14:g.87595788G>T	NCI-TCGA
rs751270575	p.Pro32Thr	missense variant	-	NC_000007.14:g.87595789G>T	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Thr33SerPheSerTerUnkUnk	frameshift	-	NC_000007.14:g.87595784_87595787AGTT>-	NCI-TCGA
rs533117495	p.Val34Ile	missense variant	-	NC_000007.14:g.87595783C>T	NCI-TCGA,NCI-TCGA Cosmic
rs533117495	p.Val34Ile	missense variant	-	NC_000007.14:g.87595783C>T	1000Genomes,ExAC,gnomAD
rs934040996	p.Ser35Asn	missense variant	-	NC_000007.14:g.87595779C>T	TOPMed,gnomAD
rs201917713	p.Met39Val	missense variant	-	NC_000007.14:g.87595768T>C	TOPMed
COSM3784092	p.Met39Lys	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87595767A>T	NCI-TCGA Cosmic
rs371192766	p.Met39Ile	missense variant	-	NC_000007.14:g.87595766C>T	ESP,ExAC,gnomAD
rs199551851	p.Arg41His	missense variant	-	NC_000007.14:g.87585676C>T	NCI-TCGA,NCI-TCGA Cosmic
COSM6178495	p.Arg41Leu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87585676C>A	NCI-TCGA Cosmic
rs761584848	p.Arg41Cys	missense variant	-	NC_000007.14:g.87585677G>A	ExAC,TOPMed,gnomAD
rs199551851	p.Arg41His	missense variant	-	NC_000007.14:g.87585676C>T	ExAC,TOPMed,gnomAD
rs761584848	p.Arg41Cys	missense variant	-	NC_000007.14:g.87585677G>A	NCI-TCGA,NCI-TCGA Cosmic
rs201564736	p.Tyr42Cys	missense variant	-	NC_000007.14:g.87585673T>C	TOPMed
rs759680987	p.Ser43Ala	missense variant	-	NC_000007.14:g.87585671A>C	ExAC,TOPMed,gnomAD
rs774528779	p.Asn44His	missense variant	-	NC_000007.14:g.87585668T>G	ExAC,TOPMed,gnomAD
rs774528779	p.Asn44Asp	missense variant	-	NC_000007.14:g.87585668T>C	ExAC,TOPMed,gnomAD
rs1202183	p.Asn44Ser	missense variant	-	NC_000007.14:g.87585667T>C	UniProt,dbSNP
VAR_055423	p.Asn44Ser	missense variant	-	NC_000007.14:g.87585667T>C	UniProt
rs1202183	p.Asn44Ser	missense variant	-	NC_000007.14:g.87585667T>C	-
rs1250463898	p.Asp47Tyr	missense variant	-	NC_000007.14:g.87585659C>A	gnomAD
rs139583955	p.Lys48Asn	missense variant	-	NC_000007.14:g.87585654C>A	1000Genomes,ExAC,TOPMed,gnomAD
rs192850609	p.Leu49Phe	missense variant	-	NC_000007.14:g.87585651C>A	1000Genomes,ExAC,TOPMed,gnomAD
rs202240722	p.Leu49Ser	missense variant	-	NC_000007.14:g.87585652A>G	ExAC,gnomAD
rs537546318	p.Tyr50Cys	missense variant	-	NC_000007.14:g.87585649T>C	1000Genomes,ExAC,TOPMed,gnomAD
rs781755669	p.Met51Thr	missense variant	-	NC_000007.14:g.87585646A>G	ExAC,gnomAD
NCI-TCGA novel	p.Gly54Arg	missense variant	-	NC_000007.14:g.87585638C>T	NCI-TCGA
rs1200080064	p.Thr55Ile	missense variant	-	NC_000007.14:g.87585634G>A	TOPMed
rs1242728976	p.Leu56Ser	missense variant	-	NC_000007.14:g.87585631A>G	TOPMed,gnomAD
rs1435532727	p.His61Tyr	missense variant	-	NC_000007.14:g.87585617G>A	gnomAD
NCI-TCGA novel	p.His61Arg	missense variant	-	NC_000007.14:g.87585616T>C	NCI-TCGA
NCI-TCGA novel	p.Gly62Glu	missense variant	-	NC_000007.14:g.87585613C>T	NCI-TCGA
COSM485675	p.Gly62Arg	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87585614C>T	NCI-TCGA Cosmic
COSM3883072	p.Ala63Asp	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87585610G>T	NCI-TCGA Cosmic
rs1388112904	p.Ala63Val	missense variant	-	NC_000007.14:g.87585610G>A	gnomAD
rs750056009	p.Ala63Thr	missense variant	-	NC_000007.14:g.87585611C>T	ExAC,TOPMed,gnomAD
rs1169254481	p.Leu67Phe	missense variant	-	NC_000007.14:g.87585599G>A	TOPMed
rs865799545	p.Met68Val	missense variant	-	NC_000007.14:g.87585596T>C	TOPMed,gnomAD
NCI-TCGA novel	p.Leu70Pro	missense variant	-	NC_000007.14:g.87585589A>G	NCI-TCGA
NCI-TCGA novel	p.Met75Ile	missense variant	-	NC_000007.14:g.87585573C>T	NCI-TCGA
NCI-TCGA novel	p.Asp77Tyr	missense variant	-	NC_000007.14:g.87585569C>A	NCI-TCGA
rs202150907	p.Ile78Thr	missense variant	-	NC_000007.14:g.87585565A>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs202150907	p.Ile78Asn	missense variant	-	NC_000007.14:g.87585565A>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs9282565	p.Ala80Glu	missense variant	-	NC_000007.14:g.87585559G>T	ExAC,gnomAD
rs1201503261	p.Ala82Val	missense variant	-	NC_000007.14:g.87585553G>A	gnomAD
NCI-TCGA novel	p.Gly83GluPheSerTerUnk	frameshift	-	NC_000007.14:g.87585552T>-	NCI-TCGA
COSM3641936	p.Gly83Glu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87585550C>T	NCI-TCGA Cosmic
rs764061195	p.Asn84His	missense variant	-	NC_000007.14:g.87585548T>G	ExAC,gnomAD
NCI-TCGA novel	p.Glu86Gln	missense variant	-	NC_000007.14:g.87585542C>G	NCI-TCGA
rs1266957400	p.Asp87Glu	missense variant	-	NC_000007.14:g.87585537A>T	TOPMed,gnomAD
rs1257387920	p.Leu88Arg	missense variant	-	NC_000007.14:g.87585535A>C	gnomAD
rs35810889	p.Met89Lys	missense variant	-	NC_000007.14:g.87585532A>T	ESP,ExAC,TOPMed,gnomAD
rs35810889	p.Met89Thr	missense variant	-	NC_000007.14:g.87585532A>G	ESP,ExAC,TOPMed,gnomAD
rs1311363553	p.Asn91Asp	missense variant	-	NC_000007.14:g.87585527T>C	TOPMed,gnomAD
rs751592416	p.Asn91Ser	missense variant	-	NC_000007.14:g.87585526T>C	ExAC,gnomAD
rs763019957	p.Thr93Ile	missense variant	-	NC_000007.14:g.87585520G>A	ExAC,TOPMed,gnomAD
rs528004506	p.Asn94Lys	missense variant	-	NC_000007.14:g.87585516A>T	1000Genomes,ExAC,TOPMed,gnomAD
COSM1092641	p.Arg95Ile	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87585514C>A	NCI-TCGA Cosmic
rs1345523838	p.Ser96Asn	missense variant	-	NC_000007.14:g.87570223C>T	gnomAD
NCI-TCGA novel	p.Asp97His	missense variant	-	NC_000007.14:g.87570221C>G	NCI-TCGA
rs1273859083	p.Ile98Ser	missense variant	-	NC_000007.14:g.87570217A>C	gnomAD
rs200693386	p.Asp100Gly	missense variant	-	NC_000007.14:g.87570211T>C	gnomAD
rs1288374568	p.Thr101Ala	missense variant	-	NC_000007.14:g.87570209T>C	NCI-TCGA Cosmic
rs1288374568	p.Thr101Ala	missense variant	-	NC_000007.14:g.87570209T>C	gnomAD
rs763159622	p.Gly102Val	missense variant	-	NC_000007.14:g.87570205C>A	ExAC,gnomAD
COSM6178496	p.Gly102Trp	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87570206C>A	NCI-TCGA Cosmic
rs199607036	p.Gly102Arg	missense variant	-	NC_000007.14:g.87570206C>T	ExAC,TOPMed,gnomAD
rs199607036	p.Gly102Arg	missense variant	-	NC_000007.14:g.87570206C>G	ExAC,TOPMed,gnomAD
COSM6178497	p.Phe103Tyr	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87570202A>T	NCI-TCGA Cosmic
VAR_015001	p.Phe103Leu	Missense	-	-	UniProt
rs750577831	p.Phe104Leu	missense variant	-	NC_000007.14:g.87570200A>G	ExAC,gnomAD
rs765543439	p.Met105Leu	missense variant	-	NC_000007.14:g.87570197T>A	ExAC,gnomAD
VAR_018351	p.Glu108Lys	Missense	-	-	UniProt
rs189559454	p.Glu109Lys	missense variant	-	NC_000007.14:g.87570185C>T	1000Genomes,ExAC,TOPMed,gnomAD
COSM6178498	p.Glu109Ter	stop gained	Variant assessed as Somatic; HIGH impact.	NC_000007.14:g.87570185C>A	NCI-TCGA Cosmic
rs201389507	p.Asp110Gly	missense variant	-	NC_000007.14:g.87570181T>C	TOPMed,gnomAD
rs769142496	p.Asp110Asn	missense variant	-	NC_000007.14:g.87570182C>T	ExAC,TOPMed,gnomAD
rs761202837	p.Met111Val	missense variant	-	NC_000007.14:g.87570179T>C	ExAC,TOPMed,gnomAD
rs761202837	p.Met111Leu	missense variant	-	NC_000007.14:g.87570179T>G	ExAC,TOPMed,gnomAD
rs1231090084	p.Arg113Gly	missense variant	-	NC_000007.14:g.87570173T>C	gnomAD
rs374713722	p.Tyr114Phe	missense variant	-	NC_000007.14:g.87566974T>A	ESP,ExAC,TOPMed,gnomAD
rs374713722	p.Tyr114Cys	missense variant	-	NC_000007.14:g.87566974T>C	ESP,ExAC,TOPMed,gnomAD
rs1366437650	p.Tyr116Cys	missense variant	-	NC_000007.14:g.87566968T>C	gnomAD
NCI-TCGA novel	p.Tyr117His	missense variant	-	NC_000007.14:g.87566966A>G	NCI-TCGA
rs1428844378	p.Ser119Asn	missense variant	-	NC_000007.14:g.87566959C>T	gnomAD
rs201352004	p.Gly120Glu	missense variant	-	NC_000007.14:g.87566956C>T	ESP,ExAC,TOPMed,gnomAD
rs759986853	p.Ala123Gly	missense variant	-	NC_000007.14:g.87566947G>C	ExAC,TOPMed,gnomAD
rs759986853	p.Ala123Val	missense variant	-	NC_000007.14:g.87566947G>A	ExAC,TOPMed,gnomAD
rs1310242458	p.Val125Leu	missense variant	-	NC_000007.14:g.87566942C>A	TOPMed,gnomAD
rs1310242458	p.Val125Met	missense variant	-	NC_000007.14:g.87566942C>T	TOPMed,gnomAD
rs368578071	p.Val127Gly	missense variant	-	NC_000007.14:g.87566935A>C	ESP,ExAC,TOPMed,gnomAD
COSM747724	p.Ala128Ser	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87566933C>A	NCI-TCGA Cosmic
rs748883796	p.Tyr130His	missense variant	-	NC_000007.14:g.87566927A>G	ExAC,gnomAD
rs1185744873	p.Ile131Val	missense variant	-	NC_000007.14:g.87566924T>C	gnomAD
rs769545558	p.Gln132Ter	stop gained	-	NC_000007.14:g.87566921G>A	ExAC,gnomAD
COSM3641934	p.Ser134Leu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87566914G>A	NCI-TCGA Cosmic
COSM3883071	p.Phe135Leu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87566910A>C	NCI-TCGA Cosmic
rs1248102071	p.Trp136Ter	stop gained	-	NC_000007.14:g.87566907C>T	gnomAD
rs1410820663	p.Cys137Ter	stop gained	-	NC_000007.14:g.87566904G>T	TOPMed,gnomAD
rs1432167827	p.Cys137Phe	missense variant	-	NC_000007.14:g.87566905C>A	TOPMed
rs754901302	p.Gly141Val	missense variant	-	NC_000007.14:g.87566893C>A	ExAC,gnomAD
COSM485674	p.Gly141Ter	stop gained	Variant assessed as Somatic; HIGH impact.	NC_000007.14:g.87566894C>A	NCI-TCGA Cosmic
rs557338866	p.Arg142Lys	missense variant	-	NC_000007.14:g.87566890C>T	1000Genomes,ExAC,gnomAD
NCI-TCGA novel	p.Gln143Lys	missense variant	-	NC_000007.14:g.87566888G>T	NCI-TCGA
rs1046070012	p.Gln143Arg	missense variant	-	NC_000007.14:g.87566887T>C	TOPMed,gnomAD
rs1459866086	p.Ile144Val	missense variant	-	NC_000007.14:g.87566885T>C	gnomAD
rs61607171	p.Ile144Thr	missense variant	-	NC_000007.14:g.87566884A>G	ESP,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Ile144Met	missense variant	-	NC_000007.14:g.87566883T>C	NCI-TCGA
NCI-TCGA novel	p.His145Asn	missense variant	-	NC_000007.14:g.87566882G>T	NCI-TCGA
rs1295245429	p.His145Arg	missense variant	-	NC_000007.14:g.87566881T>C	TOPMed,gnomAD
rs757337057	p.His145Tyr	missense variant	-	NC_000007.14:g.87566882G>A	ExAC,gnomAD
NCI-TCGA novel	p.Lys146Asn	missense variant	-	NC_000007.14:g.87566877T>G	NCI-TCGA
COSM747725	p.Arg148Thr	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87566872C>G	NCI-TCGA Cosmic
rs754111890	p.Phe151Leu	missense variant	-	NC_000007.14:g.87566864A>G	ExAC,TOPMed,gnomAD
rs754111890	p.Phe151Ile	missense variant	-	NC_000007.14:g.87566864A>T	ExAC,TOPMed,gnomAD
rs199924747	p.Phe152Val	missense variant	-	NC_000007.14:g.87566861A>C	TOPMed
COSM3778637	p.His153Tyr	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87566858G>A	NCI-TCGA Cosmic
NCI-TCGA novel	p.Ala154Asp	missense variant	-	NC_000007.14:g.87566854G>T	NCI-TCGA
NCI-TCGA novel	p.Ala154Ser	missense variant	-	NC_000007.14:g.87566855C>A	NCI-TCGA
rs149518139	p.Ile155Val	missense variant	-	NC_000007.14:g.87566852T>C	ESP
rs753065601	p.Met156Ile	missense variant	-	NC_000007.14:g.87566847C>T	ExAC,gnomAD
NCI-TCGA novel	p.Met156Lys	missense variant	-	NC_000007.14:g.87566848A>T	NCI-TCGA
rs756530200	p.Met156Leu	missense variant	-	NC_000007.14:g.87566849T>A	ExAC,TOPMed
rs202002337	p.Arg157Leu	missense variant	-	NC_000007.14:g.87566845C>A	1000Genomes,ExAC,TOPMed,gnomAD
rs1363838319	p.Arg157Ter	stop gained	-	NC_000007.14:g.87566846G>A	gnomAD
rs202002337	p.Arg157Gln	missense variant	-	NC_000007.14:g.87566845C>T	1000Genomes,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Gln158His	missense variant	-	NC_000007.14:g.87566841C>A	NCI-TCGA
rs200823786	p.Ile160Met	missense variant	-	NC_000007.14:g.87566835T>C	TOPMed
rs1183122171	p.Gly161Cys	missense variant	-	NC_000007.14:g.87566834C>A	TOPMed
NCI-TCGA novel	p.Gly161Asp	missense variant	-	NC_000007.14:g.87566833C>T	NCI-TCGA
rs1184150141	p.Trp162Cys	missense variant	-	NC_000007.14:g.87566829C>A	TOPMed,gnomAD
rs765901566	p.Phe163Val	missense variant	-	NC_000007.14:g.87566828A>C	ExAC,gnomAD
COSM747726	p.Val165Met	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87566822C>T	NCI-TCGA Cosmic
rs762489515	p.Val165Gly	missense variant	-	NC_000007.14:g.87566821A>C	ExAC,gnomAD
rs199509670	p.His166Tyr	missense variant	-	NC_000007.14:g.87566819G>A	TOPMed,gnomAD
rs769387998	p.Asp167Asn	missense variant	-	NC_000007.14:g.87566816C>T	ExAC,gnomAD
rs61122623	p.Val168Ile	missense variant	-	NC_000007.14:g.87566813C>T	ESP,ExAC,TOPMed,gnomAD
rs776417319	p.Val168Ala	missense variant	-	NC_000007.14:g.87566812A>G	ExAC,gnomAD
rs200753045	p.Thr173Pro	missense variant	-	NC_000007.14:g.87566798T>G	ESP,ExAC,TOPMed,gnomAD
rs201280497	p.Arg174Gln	missense variant	-	NC_000007.14:g.87566794C>T	ExAC,TOPMed,gnomAD
rs199808236	p.Arg174Ter	stop gained	-	NC_000007.14:g.87566795G>A	ExAC,gnomAD
rs201280497	p.Arg174Leu	missense variant	-	NC_000007.14:g.87566794C>A	ExAC,TOPMed,gnomAD
rs375817253	p.Leu175Phe	missense variant	-	NC_000007.14:g.87566792G>A	ESP,ExAC,gnomAD
NCI-TCGA novel	p.Thr176Ser	missense variant	-	NC_000007.14:g.87566789T>A	NCI-TCGA
rs201302394	p.Val179Ala	missense variant	-	NC_000007.14:g.87566236A>G	1000Genomes
rs760430324	p.Lys181Met	missense variant	-	NC_000007.14:g.87566230T>A	ExAC,TOPMed,gnomAD
rs760430324	p.Lys181Arg	missense variant	-	NC_000007.14:g.87566230T>C	ExAC,TOPMed,gnomAD
rs1188362511	p.Ile182Thr	missense variant	-	NC_000007.14:g.87566227A>G	TOPMed
rs60419673	p.Asn183Ser	missense variant	-	NC_000007.14:g.87566224T>C	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs60419673	p.Asn183Ser	missense variant	-	NC_000007.14:g.87566224T>C	NCI-TCGA,NCI-TCGA Cosmic
rs1128501	p.Gly185Val	missense variant	-	NC_000007.14:g.87566218C>A	UniProt,dbSNP
VAR_015002	p.Gly185Val	missense variant	-	NC_000007.14:g.87566218C>A	UniProt
rs1128501	p.Gly185Val	missense variant	-	NC_000007.14:g.87566218C>A	-
RCV000014697	p.Gly185Val	missense variant	-	NC_000007.14:g.87566218C>A	ClinVar
rs1455450939	p.Ile186Thr	missense variant	-	NC_000007.14:g.87566215A>G	TOPMed
rs745836011	p.Gly187Ser	missense variant	-	NC_000007.14:g.87566213C>T	ExAC,TOPMed,gnomAD
rs143782625	p.Asp188Glu	missense variant	-	NC_000007.14:g.87566208G>C	ESP,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Asp188Gly	missense variant	-	NC_000007.14:g.87566209T>C	NCI-TCGA
rs1381284304	p.Ile190Thr	missense variant	-	NC_000007.14:g.87566203A>G	gnomAD
NCI-TCGA novel	p.Ile190Met	missense variant	-	NC_000007.14:g.87566202A>C	NCI-TCGA
NCI-TCGA novel	p.Met192Thr	missense variant	-	NC_000007.14:g.87566197A>G	NCI-TCGA
rs770008344	p.Phe193Leu	missense variant	-	NC_000007.14:g.87566193G>T	ExAC,gnomAD
rs770008344	p.Phe193Leu	missense variant	-	NC_000007.14:g.87566193G>C	NCI-TCGA,NCI-TCGA Cosmic
rs770008344	p.Phe193Leu	missense variant	-	NC_000007.14:g.87566193G>C	ExAC,gnomAD
NCI-TCGA novel	p.Met197Ile	missense variant	-	NC_000007.14:g.87566181C>A	NCI-TCGA
NCI-TCGA novel	p.Met197Lys	missense variant	-	NC_000007.14:g.87566182A>T	NCI-TCGA
rs1469108355	p.Met197Thr	missense variant	-	NC_000007.14:g.87566182A>G	gnomAD
NCI-TCGA novel	p.Thr199Lys	missense variant	-	NC_000007.14:g.87566176G>T	NCI-TCGA
rs748390713	p.Thr199Ala	missense variant	-	NC_000007.14:g.87566177T>C	ExAC,TOPMed
rs1403432068	p.Thr199Ile	missense variant	-	NC_000007.14:g.87566176G>A	gnomAD
rs781337433	p.Phe200Leu	missense variant	-	NC_000007.14:g.87566174A>G	ExAC,gnomAD
COSM1452594	p.Phe201SerPheSerTerUnk	frameshift	Variant assessed as Somatic; HIGH impact.	NC_000007.14:g.87566170A>-	NCI-TCGA Cosmic
NCI-TCGA novel	p.Ile205Met	missense variant	-	NC_000007.14:g.87566157T>C	NCI-TCGA
rs755346039	p.Ile205Val	missense variant	-	NC_000007.14:g.87566159T>C	ExAC,gnomAD
rs1331678185	p.Val206Ala	missense variant	-	NC_000007.14:g.87566155A>G	TOPMed
rs371995997	p.Arg210Cys	missense variant	-	NC_000007.14:g.87566144G>A	ESP,ExAC,TOPMed,gnomAD
rs780427778	p.Lys213Glu	missense variant	-	NC_000007.14:g.87566135T>C	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Thr215ProPheSerTerUnk	frameshift	-	NC_000007.14:g.87566129T>-	NCI-TCGA
COSM3641931	p.Leu216Phe	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87566126G>A	NCI-TCGA Cosmic
rs758834776	p.Ala220Thr	missense variant	-	NC_000007.14:g.87566114C>T	ExAC,gnomAD
rs201669414	p.Ile221Met	missense variant	-	NC_000007.14:g.87566109G>C	TOPMed
rs138302009	p.Ser222Gly	missense variant	-	NC_000007.14:g.87566108T>C	ESP,TOPMed
NCI-TCGA novel	p.Pro223Thr	missense variant	-	NC_000007.14:g.87566105G>T	NCI-TCGA
COSM3924164	p.Pro223Leu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87566104G>A	NCI-TCGA Cosmic
rs1183298571	p.Ala229Thr	missense variant	-	NC_000007.14:g.87566087C>T	TOPMed,gnomAD
NCI-TCGA novel	p.Ala229Asp	missense variant	-	NC_000007.14:g.87566086G>T	NCI-TCGA
rs1183298571	p.Ala229Pro	missense variant	-	NC_000007.14:g.87566087C>G	TOPMed,gnomAD
NCI-TCGA novel	p.Ala230Thr	missense variant	-	NC_000007.14:g.87566084C>T	NCI-TCGA
COSM1452592	p.Ala230Val	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87566083G>A	NCI-TCGA Cosmic
rs750938138	p.Ala230Ser	missense variant	-	NC_000007.14:g.87566084C>A	ExAC,gnomAD
rs200191280	p.Ala230Gly	missense variant	-	NC_000007.14:g.87566083G>C	ExAC,gnomAD
rs201649109	p.Val231Leu	missense variant	-	NC_000007.14:g.87566081C>G	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Trp232Leu	missense variant	-	NC_000007.14:g.87566077C>A	NCI-TCGA
COSM6110881	p.Trp232Cys	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87566076C>A	NCI-TCGA Cosmic
NCI-TCGA novel	p.Ser237Tyr	missense variant	-	NC_000007.14:g.87561380G>T	NCI-TCGA
rs747181596	p.Ser237Pro	missense variant	-	NC_000007.14:g.87561381A>G	ExAC,gnomAD
rs370448121	p.Asp241Gly	missense variant	-	NC_000007.14:g.87561368T>C	ESP,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Lys242Ile	missense variant	-	NC_000007.14:g.87561365T>A	NCI-TCGA
NCI-TCGA novel	p.Leu245Ser	missense variant	-	NC_000007.14:g.87561356A>G	NCI-TCGA
rs201722148	p.Ala246Val	missense variant	-	NC_000007.14:g.87561353G>A	NCI-TCGA
rs201722148	p.Ala246Val	missense variant	-	NC_000007.14:g.87561353G>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1214452761	p.Tyr247Cys	missense variant	-	NC_000007.14:g.87561350T>C	gnomAD
rs1242341613	p.Tyr247His	missense variant	-	NC_000007.14:g.87561351A>G	gnomAD
rs1444836423	p.Ala248Thr	missense variant	-	NC_000007.14:g.87561348C>T	gnomAD
COSM747728	p.Lys249Glu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87561345T>C	NCI-TCGA Cosmic
NCI-TCGA novel	p.Ala250LeuPheSerTerUnk	frameshift	-	NC_000007.14:g.87561342C>-	NCI-TCGA
COSM6178499	p.Ala250Asp	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87561341G>T	NCI-TCGA Cosmic
rs755708192	p.Ala250Pro	missense variant	-	NC_000007.14:g.87561342C>G	ExAC,gnomAD
COSM6110882	p.Ala252Glu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87561335G>T	NCI-TCGA Cosmic
COSM747729	p.Glu255Gln	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87561327C>G	NCI-TCGA Cosmic
rs1313299337	p.Glu255Asp	missense variant	-	NC_000007.14:g.87561325T>G	gnomAD
rs1216695241	p.Glu256Lys	missense variant	-	NC_000007.14:g.87561324C>T	gnomAD
rs1362919289	p.Glu256Gly	missense variant	-	NC_000007.14:g.87561323T>C	gnomAD
rs1362919289	p.Glu256Ala	missense variant	-	NC_000007.14:g.87561323T>G	gnomAD
rs36008564	p.Ile261Val	missense variant	-	NC_000007.14:g.87561309T>C	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs36008564	p.Ile261Val	missense variant	-	NC_000007.14:g.87561309T>C	UniProt,dbSNP
VAR_055425	p.Ile261Val	missense variant	-	NC_000007.14:g.87561309T>C	UniProt
rs1425167192	p.Ile261Asn	missense variant	-	NC_000007.14:g.87561308A>T	gnomAD
rs202177823	p.Arg262Lys	missense variant	-	NC_000007.14:g.87561305C>T	1000Genomes,ExAC,gnomAD
rs1184324936	p.Arg262Gly	missense variant	-	NC_000007.14:g.87561306T>C	TOPMed
rs1430155491	p.Thr263Ile	missense variant	-	NC_000007.14:g.87561302G>A	gnomAD
rs773259441	p.Ala266Val	missense variant	-	NC_000007.14:g.87561293G>A	ExAC,gnomAD
COSM6178500	p.Gly269Arg	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87561285C>T	NCI-TCGA Cosmic
COSM1092635	p.Gly269Glu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87561284C>T	NCI-TCGA Cosmic
rs764072893	p.Lys272Thr	missense variant	-	NC_000007.14:g.87561275T>G	ExAC,TOPMed,gnomAD
rs1222604496	p.Glu273Ter	stop gained	-	NC_000007.14:g.87561273C>A	NCI-TCGA Cosmic
rs1222604496	p.Glu273Ter	stop gained	-	NC_000007.14:g.87561273C>A	gnomAD
rs1162562260	p.Glu273Gly	missense variant	-	NC_000007.14:g.87561272T>C	TOPMed
NCI-TCGA novel	p.Leu274Ile	missense variant	-	NC_000007.14:g.87561270G>T	NCI-TCGA
rs202097303	p.Glu275Ter	stop gained	-	NC_000007.14:g.87561267C>A	1000Genomes,ExAC,gnomAD
NCI-TCGA novel	p.Arg276Met	missense variant	-	NC_000007.14:g.87561263C>A	NCI-TCGA
rs1297328873	p.Tyr277Ter	stop gained	-	NC_000007.14:g.87553929G>T	gnomAD
rs767592386	p.Asn278Ser	missense variant	-	NC_000007.14:g.87553927T>C	ExAC
COSM1092633	p.Lys279Thr	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87553924T>G	NCI-TCGA Cosmic
NCI-TCGA novel	p.Glu282Lys	missense variant	-	NC_000007.14:g.87553916C>T	NCI-TCGA
COSM3641930	p.Glu283Lys	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87553913C>T	NCI-TCGA Cosmic
rs200148661	p.Lys285Glu	missense variant	-	NC_000007.14:g.87553907T>C	ExAC,TOPMed,gnomAD
COSM173298	p.Arg286Ile	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87553903C>A	NCI-TCGA Cosmic
rs774696910	p.Ile287Val	missense variant	-	NC_000007.14:g.87553901T>C	ExAC,gnomAD
COSM747730	p.Gly288Trp	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87553898C>A	NCI-TCGA Cosmic
COSM3641929	p.Gly288Glu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87553897C>T	NCI-TCGA Cosmic
rs1176774424	p.Ile289Val	missense variant	-	NC_000007.14:g.87553895T>C	gnomAD
rs771196019	p.Ala292Val	missense variant	-	NC_000007.14:g.87553885G>A	ExAC,gnomAD
rs763416526	p.Thr294Pro	missense variant	-	NC_000007.14:g.87553880T>G	ExAC,gnomAD
NCI-TCGA novel	p.Thr294Ala	missense variant	-	NC_000007.14:g.87553880T>C	NCI-TCGA
rs770289036	p.Ser298Phe	missense variant	-	NC_000007.14:g.87553867G>A	ExAC,gnomAD
NCI-TCGA novel	p.Ser298Tyr	missense variant	-	NC_000007.14:g.87553867G>T	NCI-TCGA
COSM747731	p.Ser298Cys	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87553867G>C	NCI-TCGA Cosmic
rs780790071	p.Ile299Val	missense variant	-	NC_000007.14:g.87553865T>C	ExAC,gnomAD
rs768339438	p.Gly300Asp	missense variant	-	NC_000007.14:g.87553861C>T	ExAC,gnomAD
rs1203320017	p.Ala302Gly	missense variant	-	NC_000007.14:g.87553855G>C	gnomAD
rs746654940	p.Phe303Leu	missense variant	-	NC_000007.14:g.87553853A>G	ExAC,TOPMed,gnomAD
rs1262510614	p.Leu305Pro	missense variant	-	NC_000007.14:g.87553846A>G	TOPMed,gnomAD
rs779792612	p.Tyr307His	missense variant	-	NC_000007.14:g.87553841A>G	ExAC,gnomAD
rs200676994	p.Tyr307Phe	missense variant	-	NC_000007.14:g.87553840T>A	ExAC,TOPMed,gnomAD
rs1237664337	p.Ala311Thr	missense variant	-	NC_000007.14:g.87553829C>T	TOPMed,gnomAD
NCI-TCGA novel	p.Ala311Asp	missense variant	-	NC_000007.14:g.87553828G>T	NCI-TCGA
rs1174023694	p.Ala313Pro	missense variant	-	NC_000007.14:g.87553823C>G	TOPMed
rs1189919755	p.Trp315Ter	stop gained	-	NC_000007.14:g.87553816C>T	gnomAD
rs778606266	p.Trp315Cys	missense variant	-	NC_000007.14:g.87553815C>A	ExAC,gnomAD
rs934392121	p.Tyr316Cys	missense variant	-	NC_000007.14:g.87553813T>C	TOPMed
COSM3883068	p.Thr318Ala	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87553808T>C	NCI-TCGA Cosmic
rs753790377	p.Thr319Asn	missense variant	-	NC_000007.14:g.87553804G>T	ExAC,gnomAD
rs1045385582	p.Thr319Ala	missense variant	-	NC_000007.14:g.87553805T>C	TOPMed,gnomAD
rs1363711355	p.Leu320Ser	missense variant	-	NC_000007.14:g.87553801A>G	gnomAD
rs201444664	p.Leu320Val	missense variant	-	NC_000007.14:g.87553802A>C	gnomAD
rs1392678819	p.Val321Ala	missense variant	-	NC_000007.14:g.87553798A>G	TOPMed
rs767576038	p.Val321Ile	missense variant	-	NC_000007.14:g.87553799C>T	ExAC,gnomAD
COSM3929233	p.Leu322Pro	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87553795A>G	NCI-TCGA Cosmic
rs573094394	p.Leu322Phe	missense variant	-	NC_000007.14:g.87553796G>A	1000Genomes,ExAC,TOPMed,gnomAD
COSM485672	p.Glu325Gly	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87553786T>C	NCI-TCGA Cosmic
rs1330170800	p.Tyr326Cys	missense variant	-	NC_000007.14:g.87553783T>C	TOPMed
COSM1092630	p.Val331Leu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87553769C>A	NCI-TCGA Cosmic
rs766673892	p.Leu332Arg	missense variant	-	NC_000007.14:g.87553765A>C	ExAC
rs1354050546	p.Ser337Tyr	missense variant	-	NC_000007.14:g.87550828G>T	gnomAD
rs773413194	p.Val338Leu	missense variant	-	NC_000007.14:g.87550826C>A	ExAC,gnomAD
rs1368324209	p.Ala342Thr	missense variant	-	NC_000007.14:g.87550814C>T	TOPMed
rs761114696	p.Val345Ala	missense variant	-	NC_000007.14:g.87550804A>G	ExAC,gnomAD
COSM3924163	p.Gly346Arg	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87550802C>T	NCI-TCGA Cosmic
rs771498736	p.Ala348Thr	missense variant	-	NC_000007.14:g.87550796C>T	ExAC
rs770682446	p.Ile352Thr	missense variant	-	NC_000007.14:g.87550783A>G	ExAC,gnomAD
rs200966236	p.Ala354Thr	missense variant	-	NC_000007.14:g.87550778C>T	ESP,ExAC,TOPMed,gnomAD
rs777570345	p.Ala356Ser	missense variant	-	NC_000007.14:g.87550772C>A	ExAC,TOPMed,gnomAD
rs1168879904	p.Ala356Glu	missense variant	-	NC_000007.14:g.87550771G>T	gnomAD
rs777570345	p.Ala356Thr	missense variant	-	NC_000007.14:g.87550772C>T	ExAC,TOPMed,gnomAD
rs1421770056	p.Ala358Gly	missense variant	-	NC_000007.14:g.87550765G>C	gnomAD
rs1201676452	p.Arg359Lys	missense variant	-	NC_000007.14:g.87550762C>T	gnomAD
rs199886416	p.Gly360Ala	missense variant	-	NC_000007.14:g.87550759C>G	TOPMed,gnomAD
rs1308529308	p.Ala361Thr	missense variant	-	NC_000007.14:g.87550757C>T	gnomAD
rs201484093	p.Ala361Val	missense variant	-	NC_000007.14:g.87550756G>A	gnomAD
COSM278523	p.Glu364Asp	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87550746T>G	NCI-TCGA Cosmic
rs1269483312	p.Ile365Asn	missense variant	-	NC_000007.14:g.87550744A>T	gnomAD
rs200671728	p.Phe366Leu	missense variant	-	NC_000007.14:g.87550740G>C	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Lys367Asn	missense variant	-	NC_000007.14:g.87550737C>A	NCI-TCGA
rs199766539	p.Ile369Val	missense variant	-	NC_000007.14:g.87550733T>C	ESP,ExAC,TOPMed,gnomAD
COSM1313361	p.Asp370His	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87550730C>G	NCI-TCGA Cosmic
rs757574551	p.Asn371Lys	missense variant	-	NC_000007.14:g.87550725A>T	ExAC,gnomAD
rs765605694	p.Asn371Tyr	missense variant	-	NC_000007.14:g.87550727T>A	ExAC,TOPMed
rs143333791	p.Pro373Ala	missense variant	-	NC_000007.14:g.87550575G>C	ESP,ExAC,TOPMed,gnomAD
rs199578136	p.Ser374Asn	missense variant	-	NC_000007.14:g.87550571C>T	ExAC,gnomAD
rs1453587307	p.Ser377Asn	missense variant	-	NC_000007.14:g.87550562C>T	gnomAD
rs754128242	p.Ser377Gly	missense variant	-	NC_000007.14:g.87550563T>C	ExAC,gnomAD
rs1394100410	p.Tyr378Cys	missense variant	-	NC_000007.14:g.87550559T>C	TOPMed
COSM6110884	p.Ser379Ter	stop gained	Variant assessed as Somatic; HIGH impact.	NC_000007.14:g.87550556G>T	NCI-TCGA Cosmic
rs762322710	p.Ser379Leu	missense variant	-	NC_000007.14:g.87550556G>A	ExAC,gnomAD
rs753217589	p.Ser381Arg	missense variant	-	NC_000007.14:g.87550549A>T	ExAC,TOPMed,gnomAD
rs1356023286	p.Gly382Arg	missense variant	-	NC_000007.14:g.87550548C>T	TOPMed
rs1410043164	p.Gly382Glu	missense variant	-	NC_000007.14:g.87550547C>T	gnomAD
rs767962530	p.His383Asn	missense variant	-	NC_000007.14:g.87550545G>T	ExAC,gnomAD
rs767962530	p.His383Tyr	missense variant	-	NC_000007.14:g.87550545G>A	ExAC,gnomAD
rs751032232	p.Asn387Asp	missense variant	-	NC_000007.14:g.87550533T>C	ExAC,gnomAD
rs149196148	p.Ile388Ser	missense variant	-	NC_000007.14:g.87550529A>C	ExAC,TOPMed,gnomAD
COSM3412443	p.Gly390Ala	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87550523C>G	NCI-TCGA Cosmic
COSM3641927	p.Gly390Glu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87550523C>T	NCI-TCGA Cosmic
rs201346512	p.Glu393Lys	missense variant	-	NC_000007.14:g.87550515C>T	ExAC,gnomAD
rs200199237	p.Glu393Ala	missense variant	-	NC_000007.14:g.87550514T>G	ExAC,gnomAD
NCI-TCGA novel	p.Phe394Leu	missense variant	-	NC_000007.14:g.87550510G>T	NCI-TCGA
COSM3641926	p.Arg395Lys	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87550508C>T	NCI-TCGA Cosmic
rs1285534379	p.Arg395Gly	missense variant	-	NC_000007.14:g.87550509T>C	gnomAD
rs761558156	p.Val397Ile	missense variant	-	NC_000007.14:g.87550503C>T	ExAC,gnomAD
rs144933300	p.His398Leu	missense variant	-	NC_000007.14:g.87550499T>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1247179537	p.Phe399Ser	missense variant	-	NC_000007.14:g.87550496A>G	gnomAD
RCV000174262	p.Ser400Asn	missense variant	-	NC_000007.14:g.87550493C>T	ClinVar
rs2229109	p.Ser400Ile	missense variant	-	NC_000007.14:g.87550493C>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs2229109	p.Ser400Asn	missense variant	-	NC_000007.14:g.87550493C>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Ser403Cys	missense variant	-	NC_000007.14:g.87550484G>C	NCI-TCGA
rs746946995	p.Ser403Tyr	missense variant	-	NC_000007.14:g.87550484G>T	ExAC,gnomAD
rs201352027	p.Arg404Gln	missense variant	-	NC_000007.14:g.87550481C>T	ExAC,TOPMed,gnomAD
COSM5408179	p.Arg404Ter	stop gained	Variant assessed as Somatic; HIGH impact.	NC_000007.14:g.87550482G>A	NCI-TCGA Cosmic
COSM3431822	p.Glu406Ter	stop gained	Variant assessed as Somatic; HIGH impact.	NC_000007.14:g.87550476C>A	NCI-TCGA Cosmic
rs200870777	p.Glu406Lys	missense variant	-	NC_000007.14:g.87550476C>T	ExAC,gnomAD
rs140214314	p.Val407Phe	missense variant	-	NC_000007.14:g.87550473C>A	ESP,ExAC,TOPMed,gnomAD
rs777898226	p.Val407Gly	missense variant	-	NC_000007.14:g.87550472A>C	ExAC,gnomAD
rs140214314	p.Val407Leu	missense variant	-	NC_000007.14:g.87550473C>G	ESP,ExAC,TOPMed,gnomAD
rs1419793187	p.Ile409Asn	missense variant	-	NC_000007.14:g.87550295A>T	gnomAD
rs1476587846	p.Gly412Ser	missense variant	-	NC_000007.14:g.87550287C>T	gnomAD
rs749429338	p.Lys416Asn	missense variant	-	NC_000007.14:g.87550273C>G	ExAC,gnomAD
rs201491802	p.Lys416Arg	missense variant	-	NC_000007.14:g.87550274T>C	gnomAD
NCI-TCGA novel	p.Val417Glu	missense variant	-	NC_000007.14:g.87550271A>T	NCI-TCGA
rs1364926780	p.Val417Met	missense variant	-	NC_000007.14:g.87550272C>T	TOPMed
rs773368293	p.Thr422Met	missense variant	-	NC_000007.14:g.87550256G>A	ExAC,TOPMed,gnomAD
rs967941491	p.Val423Leu	missense variant	-	NC_000007.14:g.87550254C>A	TOPMed
rs913766377	p.Ala424Thr	missense variant	-	NC_000007.14:g.87550251C>T	TOPMed
rs1216856095	p.Gly427Glu	missense variant	-	NC_000007.14:g.87550241C>T	gnomAD
rs952222278	p.Asn428Ser	missense variant	-	NC_000007.14:g.87550238T>C	gnomAD
COSM1452589	p.Cys431Tyr	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87550229C>T	NCI-TCGA Cosmic
rs201462032	p.Cys431Trp	missense variant	-	NC_000007.14:g.87550228A>C	ExAC,gnomAD
COSM6110886	p.Gly432Arg	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87550227C>T	NCI-TCGA Cosmic
rs201678613	p.Lys433Glu	missense variant	-	NC_000007.14:g.87550224T>C	ExAC,gnomAD
rs747479750	p.Ser434Ile	missense variant	-	NC_000007.14:g.87550220C>A	ExAC
rs1291504646	p.Thr436Ile	missense variant	-	NC_000007.14:g.87550214G>A	gnomAD
NCI-TCGA novel	p.Val437Ala	missense variant	-	NC_000007.14:g.87550211A>G	NCI-TCGA
COSM3641924	p.Gln438Ter	stop gained	Variant assessed as Somatic; HIGH impact.	NC_000007.14:g.87550209G>A	NCI-TCGA Cosmic
rs749859568	p.Leu439Pro	missense variant	-	NC_000007.14:g.87550205A>G	ExAC,gnomAD
rs756800740	p.Met440Ile	missense variant	-	NC_000007.14:g.87550201C>T	ExAC,gnomAD
rs764807184	p.Met440Val	missense variant	-	NC_000007.14:g.87550203T>C	ExAC,gnomAD
COSM3778636	p.Gln441Arg	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87550199T>C	NCI-TCGA Cosmic
rs201725784	p.Leu443Phe	missense variant	-	NC_000007.14:g.87550194G>A	1000Genomes,ExAC,TOPMed,gnomAD
rs1469116728	p.Thr447Lys	missense variant	-	NC_000007.14:g.87550181G>T	TOPMed,gnomAD
rs139611979	p.Glu448Lys	missense variant	-	NC_000007.14:g.87550179C>T	ESP,ExAC,TOPMed,gnomAD
COSM3641923	p.Gly449Arg	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87550176C>T	NCI-TCGA Cosmic
rs201987648	p.Met450Thr	missense variant	-	NC_000007.14:g.87550172A>G	TOPMed,gnomAD
NCI-TCGA novel	p.Met450Ile	missense variant	-	NC_000007.14:g.87550171C>A	NCI-TCGA
rs1223199758	p.Met450Leu	missense variant	-	NC_000007.14:g.87550173T>A	gnomAD
rs201987648	p.Met450Arg	missense variant	-	NC_000007.14:g.87550172A>C	TOPMed,gnomAD
rs1313046379	p.Ser452Gly	missense variant	-	NC_000007.14:g.87550051T>C	gnomAD
rs202187982	p.Asp454Glu	missense variant	-	NC_000007.14:g.87550043A>T	ESP,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Asp454Asn	missense variant	-	NC_000007.14:g.87550045C>T	NCI-TCGA
rs752505100	p.Gly455Glu	missense variant	-	NC_000007.14:g.87550041C>T	ExAC,gnomAD
rs1475629891	p.Gln456Glu	missense variant	-	NC_000007.14:g.87550039G>C	TOPMed
NCI-TCGA novel	p.Gln456Lys	missense variant	-	NC_000007.14:g.87550039G>T	NCI-TCGA
COSM3883066	p.Gln456Ter	stop gained	Variant assessed as Somatic; HIGH impact.	NC_000007.14:g.87550039G>A	NCI-TCGA Cosmic
COSM1092625	p.Gln456His	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87550037C>A	NCI-TCGA Cosmic
rs767429416	p.Asp457Gly	missense variant	-	NC_000007.14:g.87550035T>C	ExAC,gnomAD
rs1181024146	p.Asp457Asn	missense variant	-	NC_000007.14:g.87550036C>T	TOPMed
rs1360458780	p.Ile461Val	missense variant	-	NC_000007.14:g.87550024T>C	gnomAD
rs751575002	p.Ile461Thr	missense variant	-	NC_000007.14:g.87550023A>G	ExAC,gnomAD
rs761999329	p.Asn462Lys	missense variant	-	NC_000007.14:g.87550019A>C	ExAC,TOPMed,gnomAD
rs559003378	p.Val463Leu	missense variant	-	NC_000007.14:g.87550018C>A	1000Genomes,ExAC
rs201178758	p.Arg464Ser	missense variant	-	NC_000007.14:g.87550013C>G	ExAC,gnomAD
rs768822271	p.Arg464Gly	missense variant	-	NC_000007.14:g.87550015T>C	ExAC,gnomAD
rs760890850	p.Arg464Met	missense variant	-	NC_000007.14:g.87550014C>A	ExAC,gnomAD
rs1387356833	p.Arg467Trp	missense variant	-	NC_000007.14:g.87550006G>A	TOPMed
rs772482084	p.Arg467Gln	missense variant	-	NC_000007.14:g.87550005C>T	ExAC,gnomAD
COSM3641922	p.Glu468Lys	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87550003C>T	NCI-TCGA Cosmic
rs1187188802	p.Ile469Val	missense variant	-	NC_000007.14:g.87550000T>C	gnomAD
rs1455168926	p.Ile470Thr	missense variant	-	NC_000007.14:g.87549996A>G	TOPMed
rs1488572511	p.Gly471Cys	missense variant	-	NC_000007.14:g.87549994C>A	gnomAD
NCI-TCGA novel	p.Val472Met	missense variant	-	NC_000007.14:g.87549991C>T	NCI-TCGA
rs200183659	p.Val473Met	missense variant	-	NC_000007.14:g.87549988C>T	ExAC,gnomAD
NCI-TCGA novel	p.Val473Leu	missense variant	-	NC_000007.14:g.87549988C>G	NCI-TCGA
rs200183659	p.Val473Leu	missense variant	-	NC_000007.14:g.87549988C>A	ExAC,gnomAD
COSM3883065	p.Gln475Lys	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87549982G>T	NCI-TCGA Cosmic
rs1389565545	p.Glu476Asp	missense variant	-	NC_000007.14:g.87549977T>G	gnomAD
rs779516199	p.Pro477Thr	missense variant	-	NC_000007.14:g.87549976G>T	ExAC,gnomAD
rs1345375955	p.Phe480Leu	missense variant	-	NC_000007.14:g.87549967A>G	TOPMed
rs1361374723	p.Ala481Asp	missense variant	-	NC_000007.14:g.87549963G>T	gnomAD
rs199720786	p.Thr482Ile	missense variant	-	NC_000007.14:g.87549960G>A	1000Genomes,ExAC,gnomAD
NCI-TCGA novel	p.Thr483Met	missense variant	-	NC_000007.14:g.87549957G>A	NCI-TCGA
rs1338355304	p.Ile488Val	missense variant	-	NC_000007.14:g.87549943T>C	gnomAD
rs142600685	p.Arg489Cys	missense variant	-	NC_000007.14:g.87549940G>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs750696034	p.Arg489Leu	missense variant	-	NC_000007.14:g.87549939C>A	ExAC,gnomAD
rs750696034	p.Arg489His	missense variant	-	NC_000007.14:g.87549939C>T	ExAC,gnomAD
rs781123430	p.Tyr490Cys	missense variant	-	NC_000007.14:g.87549936T>C	ExAC,gnomAD
rs754872565	p.Arg492Cys	missense variant	-	NC_000007.14:g.87549931G>A	ExAC,TOPMed,gnomAD
COSM6110888	p.Arg492Leu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87549930C>A	NCI-TCGA Cosmic
rs199941458	p.Arg492His	missense variant	-	NC_000007.14:g.87549930C>T	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Asn494Asp	missense variant	-	NC_000007.14:g.87549925T>C	NCI-TCGA
COSM1092622	p.Asn494His	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87549925T>G	NCI-TCGA Cosmic
rs762825426	p.Val495Ile	missense variant	-	NC_000007.14:g.87549922C>T	ExAC,TOPMed,gnomAD
rs553667487	p.Met497Val	missense variant	-	NC_000007.14:g.87549916T>C	1000Genomes,ExAC,TOPMed,gnomAD
rs760874215	p.Asp498Gly	missense variant	-	NC_000007.14:g.87549912T>C	ExAC,gnomAD
rs1171458375	p.Asp498Tyr	missense variant	-	NC_000007.14:g.87549913C>A	TOPMed,gnomAD
rs201761318	p.Ile500Thr	missense variant	-	NC_000007.14:g.87549906A>G	ExAC,gnomAD
NCI-TCGA novel	p.Glu501Lys	missense variant	-	NC_000007.14:g.87549904C>T	NCI-TCGA
rs1191361542	p.Lys502Ter	stop gained	-	NC_000007.14:g.87549901T>A	gnomAD
rs772393045	p.Val504Leu	missense variant	-	NC_000007.14:g.87549895C>G	ExAC,gnomAD
rs759995973	p.Glu506Lys	missense variant	-	NC_000007.14:g.87549889C>T	ExAC,TOPMed,gnomAD
rs771429713	p.Ala507Gly	missense variant	-	NC_000007.14:g.87549885G>C	ExAC,TOPMed,gnomAD
COSM256223	p.Ala507Thr	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87549886C>T	NCI-TCGA Cosmic
rs771429713	p.Ala507Val	missense variant	-	NC_000007.14:g.87549885G>A	ExAC,TOPMed,gnomAD
rs535338471	p.Asn508Ser	missense variant	-	NC_000007.14:g.87549882T>C	1000Genomes,ExAC,gnomAD
NCI-TCGA novel	p.Ile513Phe	missense variant	-	NC_000007.14:g.87549868T>A	NCI-TCGA
rs148455513	p.Met514Val	missense variant	-	NC_000007.14:g.87549865T>C	ESP,ExAC,TOPMed,gnomAD
COSM1452588	p.Met514Ile	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87549863C>T	NCI-TCGA Cosmic
rs1218688694	p.Met514Thr	missense variant	-	NC_000007.14:g.87549864A>G	gnomAD
COSM1092621	p.His518Arg	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87549852T>C	NCI-TCGA Cosmic
rs1275791615	p.His518Gln	missense variant	-	NC_000007.14:g.87549851A>T	gnomAD
rs1468184660	p.His518Tyr	missense variant	-	NC_000007.14:g.87549853G>A	TOPMed
COSM453510	p.Asp521His	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87549512C>G	NCI-TCGA Cosmic
rs774711495	p.Asp521Gly	missense variant	-	NC_000007.14:g.87549511T>C	ExAC,gnomAD
rs201159898	p.Thr522Ala	missense variant	-	NC_000007.14:g.87549509T>C	1000Genomes,ExAC,TOPMed,gnomAD
rs1398389130	p.Thr522Asn	missense variant	-	NC_000007.14:g.87549508G>T	gnomAD
rs201159898	p.Thr522Ser	missense variant	-	NC_000007.14:g.87549509T>A	1000Genomes,ExAC,TOPMed,gnomAD
rs1324520636	p.Leu523Val	missense variant	-	NC_000007.14:g.87549506G>C	TOPMed
rs773925485	p.Glu526Asp	missense variant	-	NC_000007.14:g.87549495C>G	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Arg527Lys	missense variant	-	NC_000007.14:g.87549493C>T	NCI-TCGA
rs769400173	p.Ala529Pro	missense variant	-	NC_000007.14:g.87549488C>G	ExAC,gnomAD
rs745745163	p.Ala529ProPheSerTerUnkUnk	frameshift	-	NC_000007.14:g.87549491_87549492CT>-	NCI-TCGA,NCI-TCGA Cosmic
rs1477018410	p.Leu531Trp	missense variant	-	NC_000007.14:g.87549481A>C	TOPMed,gnomAD
NCI-TCGA novel	p.Leu531Phe	missense variant	-	NC_000007.14:g.87549480C>G	NCI-TCGA
rs1274564250	p.Ser532Thr	missense variant	-	NC_000007.14:g.87549478C>G	TOPMed
rs768283170	p.Ser532Gly	missense variant	-	NC_000007.14:g.87549479T>C	ExAC,gnomAD
rs1179026893	p.Gly534Val	missense variant	-	NC_000007.14:g.87549472C>A	gnomAD
COSM1092620	p.Gln535Ter	stop gained	Variant assessed as Somatic; HIGH impact.	NC_000007.14:g.87549470G>A	NCI-TCGA Cosmic
COSM4904965	p.Gln535His	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87549468C>A	NCI-TCGA Cosmic
rs746652079	p.Lys536Gln	missense variant	-	NC_000007.14:g.87549467T>G	ExAC,TOPMed,gnomAD
rs758194199	p.Arg538Ser	missense variant	-	NC_000007.14:g.87549459C>A	ExAC,gnomAD
rs201188762	p.Ala540Ser	missense variant	-	NC_000007.14:g.87549455C>A	TOPMed,gnomAD
rs201188762	p.Ala540Thr	missense variant	-	NC_000007.14:g.87549455C>T	TOPMed,gnomAD
rs1353480925	p.Ile541Val	missense variant	-	NC_000007.14:g.87549452T>C	gnomAD
rs778869420	p.Ile541Met	missense variant	-	NC_000007.14:g.87549450A>C	ExAC,TOPMed,gnomAD
rs1374940464	p.Arg543Pro	missense variant	-	NC_000007.14:g.87549445C>G	gnomAD
rs1374940464	p.Arg543His	missense variant	-	NC_000007.14:g.87549445C>T	gnomAD
rs757210054	p.Arg543Cys	missense variant	-	NC_000007.14:g.87549446G>A	ExAC,TOPMed,gnomAD
rs974595753	p.Ala544Val	missense variant	-	NC_000007.14:g.87549442G>A	TOPMed,gnomAD
rs202111093	p.Ala544Thr	missense variant	-	NC_000007.14:g.87549443C>T	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Leu545Gln	missense variant	-	NC_000007.14:g.87549439A>T	NCI-TCGA
NCI-TCGA novel	p.Leu545TrpPheSerTerUnkUnk	frameshift	-	NC_000007.14:g.87549440G>-	NCI-TCGA
rs199852575	p.Arg547Cys	missense variant	-	NC_000007.14:g.87549434G>A	ExAC,gnomAD
rs763454753	p.Arg547His	missense variant	-	NC_000007.14:g.87549433C>T	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Pro549His	missense variant	-	NC_000007.14:g.87549427G>T	NCI-TCGA
rs1018838697	p.Pro549Thr	missense variant	-	NC_000007.14:g.87549428G>T	gnomAD
rs1018838697	p.Pro549Ser	missense variant	-	NC_000007.14:g.87549428G>A	gnomAD
NCI-TCGA novel	p.Lys550Asn	missense variant	-	NC_000007.14:g.87549423C>A	NCI-TCGA
rs762410817	p.Asp555Ala	missense variant	-	NC_000007.14:g.87549409T>G	ExAC,TOPMed,gnomAD
rs762410817	p.Asp555Gly	missense variant	-	NC_000007.14:g.87549409T>C	ExAC,TOPMed,gnomAD
rs1236320337	p.Glu556Asp	missense variant	-	NC_000007.14:g.87549405C>G	gnomAD
rs371019082	p.Ala557Gly	missense variant	-	NC_000007.14:g.87549403G>C	ESP,ExAC,TOPMed,gnomAD
rs370804452	p.Thr558Met	missense variant	-	NC_000007.14:g.87549400G>A	ESP,ExAC,gnomAD
rs201641803	p.Leu561Phe	missense variant	-	NC_000007.14:g.87549390C>A	ExAC,gnomAD
NCI-TCGA novel	p.Asp562Gly	missense variant	-	NC_000007.14:g.87549388T>C	NCI-TCGA
rs1177169246	p.Ser565Asn	missense variant	-	NC_000007.14:g.87549379C>T	gnomAD
rs28381902	p.Glu566Lys	missense variant	-	NC_000007.14:g.87549377C>T	ExAC,TOPMed,gnomAD
rs1355931317	p.Ala567Thr	missense variant	-	NC_000007.14:g.87549374C>T	gnomAD
rs755085099	p.Val571Met	missense variant	-	NC_000007.14:g.87549362C>T	ExAC,gnomAD
COSM3883062	p.Ala572Val	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87549358G>A	NCI-TCGA Cosmic
rs199659428	p.Asp574Val	missense variant	-	NC_000007.14:g.87549352T>A	TOPMed
rs770568187	p.Asp574Tyr	missense variant	-	NC_000007.14:g.87549353C>A	TOPMed,gnomAD
rs770568187	p.Asp574Asn	missense variant	-	NC_000007.14:g.87549353C>T	TOPMed,gnomAD
rs1423665718	p.Ala576Pro	missense variant	-	NC_000007.14:g.87546024C>G	gnomAD
rs1169358648	p.Ala576Gly	missense variant	-	NC_000007.14:g.87546023G>C	gnomAD
rs780182297	p.Gly579Cys	missense variant	-	NC_000007.14:g.87546015C>A	ExAC,TOPMed,gnomAD
rs200224345	p.Arg580Trp	missense variant	-	NC_000007.14:g.87546012G>A	TOPMed,gnomAD
rs202017838	p.Arg580Pro	missense variant	-	NC_000007.14:g.87546011C>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs202017838	p.Arg580Gln	missense variant	-	NC_000007.14:g.87546011C>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1375846757	p.Thr581Ala	missense variant	-	NC_000007.14:g.87546009T>C	TOPMed
rs779414215	p.Thr581Ser	missense variant	-	NC_000007.14:g.87546008G>C	ExAC,gnomAD
NCI-TCGA novel	p.Thr582Ala	missense variant	-	NC_000007.14:g.87546006T>C	NCI-TCGA
rs1458392780	p.Ile583Thr	missense variant	-	NC_000007.14:g.87546002A>G	gnomAD
rs1200702337	p.Ile583Val	missense variant	-	NC_000007.14:g.87546003T>C	TOPMed,gnomAD
rs1257424474	p.Val584Met	missense variant	-	NC_000007.14:g.87546000C>T	gnomAD
rs757734033	p.Ala586Thr	missense variant	-	NC_000007.14:g.87545994C>T	ExAC,gnomAD
rs201122883	p.Arg588Cys	missense variant	-	NC_000007.14:g.87545988G>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs966775931	p.Ser590Phe	missense variant	-	NC_000007.14:g.87545981G>A	TOPMed
rs764459400	p.Thr591Ala	missense variant	-	NC_000007.14:g.87545979T>C	ExAC,gnomAD
rs56107566	p.Arg593His	missense variant	-	NC_000007.14:g.87545972C>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs28381914	p.Arg593Ser	missense variant	-	NC_000007.14:g.87545973G>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs28381914	p.Arg593Cys	missense variant	-	NC_000007.14:g.87545973G>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1280797442	p.Asn594Lys	missense variant	-	NC_000007.14:g.87545968A>T	TOPMed
COSM485669	p.Ala595Gly	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87545966G>C	NCI-TCGA Cosmic
rs767030297	p.Ala595Thr	missense variant	-	NC_000007.14:g.87545967C>T	ExAC,gnomAD
rs759177745	p.Asp596Asn	missense variant	-	NC_000007.14:g.87545964C>T	ExAC,gnomAD
rs199931362	p.Val597Leu	missense variant	-	NC_000007.14:g.87545961C>G	1000Genomes,ExAC,TOPMed,gnomAD
COSM1452586	p.Val597Ala	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87545960A>G	NCI-TCGA Cosmic
rs199931362	p.Val597Ile	missense variant	-	NC_000007.14:g.87545961C>T	1000Genomes,ExAC,TOPMed,gnomAD
rs2235036	p.Ala599Thr	missense variant	-	NC_000007.14:g.87545955C>T	ExAC,TOPMed,gnomAD
rs2235036	p.Ala599Thr	missense variant	-	NC_000007.14:g.87545955C>T	UniProt,dbSNP
VAR_055426	p.Ala599Thr	missense variant	-	NC_000007.14:g.87545955C>T	UniProt
NCI-TCGA novel	p.Gly600Val	missense variant	-	NC_000007.14:g.87545951C>A	NCI-TCGA
rs748125208	p.Gly600Asp	missense variant	-	NC_000007.14:g.87545951C>T	ExAC,gnomAD
rs748125208	p.Gly600Ala	missense variant	-	NC_000007.14:g.87545951C>G	ExAC,gnomAD
rs201365503	p.Asp602Asn	missense variant	-	NC_000007.14:g.87545946C>T	1000Genomes,ExAC,TOPMed,gnomAD
rs201365503	p.Asp602Tyr	missense variant	-	NC_000007.14:g.87545946C>A	1000Genomes,ExAC,TOPMed,gnomAD
rs746054969	p.Asp603His	missense variant	-	NC_000007.14:g.87545943C>G	ExAC,gnomAD
rs746054969	p.Asp603Tyr	missense variant	-	NC_000007.14:g.87545943C>A	ExAC,gnomAD
rs757574649	p.Asp603Glu	missense variant	-	NC_000007.14:g.87545941A>T	ExAC,TOPMed,gnomAD
COSM1092617	p.Gly604Glu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87545939C>T	NCI-TCGA Cosmic
NCI-TCGA novel	p.Val605Ile	missense variant	-	NC_000007.14:g.87545937C>T	NCI-TCGA
rs749574370	p.Ile606Leu	missense variant	-	NC_000007.14:g.87545934T>G	ExAC,TOPMed,gnomAD
rs749574370	p.Ile606Phe	missense variant	-	NC_000007.14:g.87545934T>A	ExAC,TOPMed,gnomAD
rs149359465	p.Val607Met	missense variant	-	NC_000007.14:g.87545931C>T	ESP,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Lys609Asn	missense variant	-	NC_000007.14:g.87545923T>A	NCI-TCGA
NCI-TCGA novel	p.Lys609Glu	missense variant	-	NC_000007.14:g.87545925T>C	NCI-TCGA
COSM1698852	p.Gly610Glu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87545921C>T	NCI-TCGA Cosmic
rs1213042982	p.Gly610Arg	missense variant	-	NC_000007.14:g.87545922C>T	gnomAD
rs57001392	p.Asp613Tyr	missense variant	-	NC_000007.14:g.87545913C>A	ExAC,gnomAD
COSM3924162	p.Glu614Lys	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87545910C>T	NCI-TCGA Cosmic
rs767011913	p.Glu614Asp	missense variant	-	NC_000007.14:g.87545908T>G	ExAC,gnomAD
rs1242139767	p.Leu615Pro	missense variant	-	NC_000007.14:g.87545906A>G	TOPMed,gnomAD
rs1277845808	p.Leu615Val	missense variant	-	NC_000007.14:g.87545907G>C	gnomAD
rs1242139767	p.Leu615His	missense variant	-	NC_000007.14:g.87545906A>T	TOPMed,gnomAD
rs1308127826	p.Met616Lys	missense variant	-	NC_000007.14:g.87545903A>T	gnomAD
COSM1092616	p.Glu618Gln	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87545898C>G	NCI-TCGA Cosmic
rs1435673611	p.Lys619Glu	missense variant	-	NC_000007.14:g.87545895T>C	TOPMed
rs765970736	p.Gly620Asp	missense variant	-	NC_000007.14:g.87545891C>T	ExAC,TOPMed,gnomAD
rs772821889	p.Phe623Leu	missense variant	-	NC_000007.14:g.87545883A>G	ExAC,gnomAD
rs141018820	p.Lys624Arg	missense variant	-	NC_000007.14:g.87545879T>C	ESP,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Val626Ala	missense variant	-	NC_000007.14:g.87545873A>G	NCI-TCGA
rs1160807373	p.Thr627Pro	missense variant	-	NC_000007.14:g.87545871T>G	gnomAD
rs1420748687	p.Met628Val	missense variant	-	NC_000007.14:g.87545868T>C	gnomAD
rs1373168864	p.Ala631Thr	missense variant	-	NC_000007.14:g.87544996C>T	gnomAD
rs1203228011	p.Asn633Lys	missense variant	-	NC_000007.14:g.87544988A>T	gnomAD
NCI-TCGA novel	p.Glu634Lys	missense variant	-	NC_000007.14:g.87544987C>T	NCI-TCGA
NCI-TCGA novel	p.Glu634Ter	stop gained	-	NC_000007.14:g.87544987C>A	NCI-TCGA
rs764906803	p.Val635Ala	missense variant	-	NC_000007.14:g.87544983A>G	ExAC,gnomAD
rs1265709861	p.Glu636Ter	stop gained	-	NC_000007.14:g.87544981C>A	gnomAD
rs1265709861	p.Glu636Lys	missense variant	-	NC_000007.14:g.87544981C>T	gnomAD
rs1480244258	p.Glu638Ala	missense variant	-	NC_000007.14:g.87544974T>G	TOPMed
rs748496246	p.Ala641Gly	missense variant	-	NC_000007.14:g.87544965G>C	ExAC,gnomAD
NCI-TCGA novel	p.Ala641Thr	missense variant	-	NC_000007.14:g.87544966C>T	NCI-TCGA
NCI-TCGA novel	p.Asp642MetPheSerTerUnkUnk	frameshift	-	NC_000007.14:g.87544964A>-	NCI-TCGA
NCI-TCGA novel	p.Asp642Asn	missense variant	-	NC_000007.14:g.87544963C>T	NCI-TCGA
rs201352373	p.Asp642Val	missense variant	-	NC_000007.14:g.87544962T>A	ESP,ExAC,gnomAD
rs528939709	p.Ser646Ile	missense variant	-	NC_000007.14:g.87544950C>A	1000Genomes,ExAC,gnomAD
NCI-TCGA novel	p.Ser646ValPheSerTerUnkUnk	frameshift	-	NC_000007.14:g.87544951T>-	NCI-TCGA
rs771100656	p.Glu647Lys	missense variant	-	NC_000007.14:g.87544948C>T	ExAC,gnomAD
rs773525613	p.Ile648Thr	missense variant	-	NC_000007.14:g.87544944A>G	ExAC,TOPMed,gnomAD
rs1415499957	p.Ile648Val	missense variant	-	NC_000007.14:g.87544945T>C	gnomAD
rs773525613	p.Ile648Ser	missense variant	-	NC_000007.14:g.87544944A>C	ExAC,TOPMed,gnomAD
rs1391697654	p.Asp649Asn	missense variant	-	NC_000007.14:g.87544942C>T	gnomAD
rs200378616	p.Ala650Gly	missense variant	-	NC_000007.14:g.87544938G>C	ESP,ExAC,TOPMed,gnomAD
rs200378616	p.Ala650Asp	missense variant	-	NC_000007.14:g.87544938G>T	ESP,ExAC,TOPMed,gnomAD
rs1402478835	p.Ser654Pro	missense variant	-	NC_000007.14:g.87544927A>G	gnomAD
rs1171481420	p.Ser655Pro	missense variant	-	NC_000007.14:g.87544924A>G	TOPMed,gnomAD
rs1478102663	p.Asn656Lys	missense variant	-	NC_000007.14:g.87544919A>C	gnomAD
rs1434727302	p.Asp657Glu	missense variant	-	NC_000007.14:g.87544916A>C	gnomAD
rs1372487776	p.Asp657Tyr	missense variant	-	NC_000007.14:g.87544918C>A	gnomAD
rs781571880	p.Asp657Gly	missense variant	-	NC_000007.14:g.87544917T>C	ExAC,gnomAD
COSM1452585	p.Ser658Pro	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87544915A>G	NCI-TCGA Cosmic
COSM3431821	p.Arg659Ile	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87544911C>A	NCI-TCGA Cosmic
rs769089888	p.Ser661Asn	missense variant	-	NC_000007.14:g.87544905C>T	ExAC,TOPMed,gnomAD
rs35657960	p.Leu662Arg	missense variant	-	NC_000007.14:g.87544902A>C	1000Genomes,ESP,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Leu662Ile	missense variant	-	NC_000007.14:g.87544903G>T	NCI-TCGA
COSM1092614	p.Arg664Ile	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87544896C>A	NCI-TCGA Cosmic
rs145840638	p.Lys665Gln	missense variant	-	NC_000007.14:g.87544894T>G	ExAC,TOPMed,gnomAD
rs750020655	p.Arg666Ile	missense variant	-	NC_000007.14:g.87544890C>A	ExAC,gnomAD
NCI-TCGA novel	p.Ser667Leu	missense variant	-	NC_000007.14:g.87544887G>A	NCI-TCGA
rs778576220	p.Thr668Ala	missense variant	-	NC_000007.14:g.87544885T>C	ExAC,gnomAD
rs146703713	p.Arg669His	missense variant	-	NC_000007.14:g.87544881C>T	ESP,ExAC,TOPMed,gnomAD
rs35023033	p.Arg669Cys	missense variant	-	NC_000007.14:g.87544882G>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs146703713	p.Arg669Leu	missense variant	-	NC_000007.14:g.87544881C>A	ESP,ExAC,TOPMed,gnomAD
rs35023033	p.Arg669Ser	missense variant	-	NC_000007.14:g.87544882G>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs201298259	p.Arg670Lys	missense variant	-	NC_000007.14:g.87544878C>T	ExAC,gnomAD
rs766339610	p.Ser671Arg	missense variant	-	NC_000007.14:g.87544874A>C	ExAC,gnomAD
rs200178485	p.Ser671Asn	missense variant	-	NC_000007.14:g.87544875C>T	gnomAD
rs983438430	p.Ser671Arg	missense variant	-	NC_000007.14:g.87544876T>G	gnomAD
NCI-TCGA novel	p.Val672Ile	missense variant	-	NC_000007.14:g.87544873C>T	NCI-TCGA
rs200859389	p.Arg673Cys	missense variant	-	NC_000007.14:g.87544870G>A	ExAC,TOPMed,gnomAD
rs184290374	p.Arg673His	missense variant	-	NC_000007.14:g.87544869C>T	1000Genomes,ExAC,gnomAD
NCI-TCGA novel	p.Gly674Val	missense variant	-	NC_000007.14:g.87544866C>A	NCI-TCGA
COSM747735	p.Gly674Ter	stop gained	Variant assessed as Somatic; HIGH impact.	NC_000007.14:g.87544867C>A	NCI-TCGA Cosmic
COSM747736	p.Gly674Ala	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87544866C>G	NCI-TCGA Cosmic
rs59340265	p.Asp679Glu	missense variant	-	NC_000007.14:g.87544850G>C	ExAC,gnomAD
rs952145392	p.Asp679His	missense variant	-	NC_000007.14:g.87544852C>G	gnomAD
rs201355162	p.Arg680Gly	missense variant	-	NC_000007.14:g.87544849T>C	TOPMed
COSM1313360	p.Lys681Glu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87544846T>C	NCI-TCGA Cosmic
rs1323794979	p.Leu682Val	missense variant	-	NC_000007.14:g.87544843G>C	TOPMed,gnomAD
rs1323794979	p.Leu682Phe	missense variant	-	NC_000007.14:g.87544843G>A	TOPMed,gnomAD
NCI-TCGA novel	p.Ser683Thr	missense variant	-	NC_000007.14:g.87544839C>G	NCI-TCGA
rs1027717457	p.Thr684Asn	missense variant	-	NC_000007.14:g.87544836G>T	TOPMed,gnomAD
rs1027717457	p.Thr684Ile	missense variant	-	NC_000007.14:g.87544836G>A	TOPMed,gnomAD
rs1271391029	p.Ala687Val	missense variant	-	NC_000007.14:g.87544827G>A	TOPMed
NCI-TCGA novel	p.Ala687Asp	missense variant	-	NC_000007.14:g.87544827G>T	NCI-TCGA
rs1043070641	p.Ala687Pro	missense variant	-	NC_000007.14:g.87544828C>G	TOPMed
NCI-TCGA novel	p.Leu688Val	missense variant	-	NC_000007.14:g.87544825G>C	NCI-TCGA
rs1189101528	p.Asp689Gly	missense variant	-	NC_000007.14:g.87544274T>C	gnomAD
rs921088140	p.Glu690Lys	missense variant	-	NC_000007.14:g.87544272C>T	TOPMed
rs764417353	p.Ile692Val	missense variant	-	NC_000007.14:g.87544266T>C	ExAC,gnomAD
rs760977802	p.Pro694Leu	missense variant	-	NC_000007.14:g.87544259G>A	ExAC,gnomAD
COSM3641918	p.Ser696Phe	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87544253G>A	NCI-TCGA Cosmic
NCI-TCGA novel	p.Phe697Cys	missense variant	-	NC_000007.14:g.87544250A>C	NCI-TCGA
COSM3641917	p.Met701Ile	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87544237C>T	NCI-TCGA Cosmic
rs772563512	p.Met701Val	missense variant	-	NC_000007.14:g.87544239T>C	ExAC,TOPMed,gnomAD
rs773899676	p.Thr706Asn	missense variant	-	NC_000007.14:g.87544223G>T	ExAC,gnomAD
NCI-TCGA novel	p.Glu707Ter	stop gained	-	NC_000007.14:g.87544221C>A	NCI-TCGA
rs1331432775	p.Trp708Cys	missense variant	-	NC_000007.14:g.87544216C>A	TOPMed
rs1226611649	p.Val712Ala	missense variant	-	NC_000007.14:g.87544205A>G	TOPMed
rs576829142	p.Val713Gly	missense variant	-	NC_000007.14:g.87544202A>C	1000Genomes,ExAC,TOPMed,gnomAD
rs1286029307	p.Val713Ile	missense variant	-	NC_000007.14:g.87544203C>T	gnomAD
rs748919574	p.Gly714Ala	missense variant	-	NC_000007.14:g.87544199C>G	ExAC,TOPMed,gnomAD
rs1205336910	p.Phe716Leu	missense variant	-	NC_000007.14:g.87544194A>G	TOPMed
NCI-TCGA novel	p.Ala718Asp	missense variant	-	NC_000007.14:g.87544187G>T	NCI-TCGA
COSM3883060	p.Ala718Val	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87544187G>A	NCI-TCGA Cosmic
rs1020594116	p.Ile720Val	missense variant	-	NC_000007.14:g.87544182T>C	TOPMed,gnomAD
rs1020594116	p.Ile720Leu	missense variant	-	NC_000007.14:g.87544182T>A	TOPMed,gnomAD
rs1298586570	p.Asn721Ser	missense variant	-	NC_000007.14:g.87544178T>C	TOPMed,gnomAD
COSM3924161	p.Gly722Glu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87544175C>T	NCI-TCGA Cosmic
COSM69486	p.Gly722Val	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87544175C>A	NCI-TCGA Cosmic
COSM1330485	p.Leu724Met	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87544170G>T	NCI-TCGA Cosmic
rs755856690	p.Gln725Arg	missense variant	-	NC_000007.14:g.87544166T>C	ExAC,gnomAD
rs780857986	p.Ala727Val	missense variant	-	NC_000007.14:g.87544160G>A	ExAC,gnomAD
COSM1452583	p.Ile731Leu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87544149T>G	NCI-TCGA Cosmic
rs1419673180	p.Ile731Met	missense variant	-	NC_000007.14:g.87544147T>C	TOPMed,gnomAD
NCI-TCGA novel	p.Ser733Ter	stop gained	-	NC_000007.14:g.87544142G>T	NCI-TCGA
rs1392639104	p.Ile735Val	missense variant	-	NC_000007.14:g.87544137T>C	TOPMed
rs200519232	p.Ile736Leu	missense variant	-	NC_000007.14:g.87544134T>G	gnomAD
rs1296251129	p.Val738Ile	missense variant	-	NC_000007.14:g.87541464C>T	gnomAD
NCI-TCGA novel	p.Phe739Leu	missense variant	-	NC_000007.14:g.87541459A>T	NCI-TCGA
rs769508094	p.Thr740Ile	missense variant	-	NC_000007.14:g.87541457G>A	ExAC,TOPMed,gnomAD
rs1359542599	p.Arg741Ile	missense variant	-	NC_000007.14:g.87541454C>A	TOPMed,gnomAD
COSM3641916	p.Asp744Asn	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87541446C>T	NCI-TCGA Cosmic
rs747772100	p.Asp744Glu	missense variant	-	NC_000007.14:g.87541444A>T	ExAC,gnomAD
NCI-TCGA novel	p.Glu746Lys	missense variant	-	NC_000007.14:g.87541440C>T	NCI-TCGA
NCI-TCGA novel	p.Lys748Thr	missense variant	-	NC_000007.14:g.87541433T>G	NCI-TCGA
rs754765644	p.Arg749Leu	missense variant	-	NC_000007.14:g.87541430C>A	ExAC,TOPMed,gnomAD
rs754765644	p.Arg749Gln	missense variant	-	NC_000007.14:g.87541430C>T	ExAC,TOPMed,gnomAD
rs1323297861	p.Arg749Ter	stop gained	-	NC_000007.14:g.87541431G>A	gnomAD
rs200152744	p.Asn753Asp	missense variant	-	NC_000007.14:g.87541419T>C	ExAC,TOPMed,gnomAD
rs1408739324	p.Leu754Phe	missense variant	-	NC_000007.14:g.87541414C>A	TOPMed,gnomAD
rs1271272875	p.Leu754Trp	missense variant	-	NC_000007.14:g.87541415A>C	TOPMed
COSM1092611	p.Phe755Leu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87541413A>G	NCI-TCGA Cosmic
rs975854106	p.Leu757Pro	missense variant	-	NC_000007.14:g.87541406A>G	TOPMed,gnomAD
rs1453981427	p.Leu758Ter	stop gained	-	NC_000007.14:g.87541403A>T	gnomAD
rs375295612	p.Phe759Val	missense variant	-	NC_000007.14:g.87541401A>C	ESP,TOPMed
NCI-TCGA novel	p.Leu760Ile	missense variant	-	NC_000007.14:g.87541398G>T	NCI-TCGA
COSM747739	p.Leu760Pro	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87541397A>G	NCI-TCGA Cosmic
rs1251424548	p.Leu760Val	missense variant	-	NC_000007.14:g.87541398G>C	gnomAD
COSM1092610	p.Gly763Val	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87541388C>A	NCI-TCGA Cosmic
rs779916152	p.Ile765Val	missense variant	-	NC_000007.14:g.87541383T>C	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Ser766Tyr	missense variant	-	NC_000007.14:g.87541379G>T	NCI-TCGA
COSM1452581	p.Ser766Thr	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87541380A>T	NCI-TCGA Cosmic
rs149038363	p.Ile768Val	missense variant	-	NC_000007.14:g.87541374T>C	ESP,TOPMed,gnomAD
rs1250849808	p.Thr769Ala	missense variant	-	NC_000007.14:g.87541371T>C	gnomAD
COSM3641914	p.Leu772Phe	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87541362G>A	NCI-TCGA Cosmic
rs753847579	p.Leu772His	missense variant	-	NC_000007.14:g.87541361A>T	ExAC,gnomAD
COSM1488745	p.Gly774Ser	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87539345C>T	NCI-TCGA Cosmic
rs199564535	p.Gly774Arg	missense variant	-	NC_000007.14:g.87539345C>G	ExAC,gnomAD
rs372521819	p.Thr776Lys	missense variant	-	NC_000007.14:g.87539338G>T	ESP
rs1381927860	p.Phe777Leu	missense variant	-	NC_000007.14:g.87539334A>C	gnomAD
rs1369989041	p.Lys779Glu	missense variant	-	NC_000007.14:g.87539330T>C	TOPMed
rs1220754414	p.Thr785Ser	missense variant	-	NC_000007.14:g.87539311G>C	TOPMed
rs200903110	p.Arg787Trp	missense variant	-	NC_000007.14:g.87539306G>A	ESP,ExAC,gnomAD
rs199779996	p.Arg789Gln	missense variant	-	NC_000007.14:g.87539299C>T	-
rs1373964332	p.Arg789Ter	stop gained	-	NC_000007.14:g.87539300G>A	gnomAD
NCI-TCGA novel	p.Tyr790Cys	missense variant	-	NC_000007.14:g.87539296T>C	NCI-TCGA
rs201661522	p.Met791Thr	missense variant	-	NC_000007.14:g.87539293A>G	1000Genomes,ExAC,TOPMed,gnomAD
rs756188258	p.Met791Val	missense variant	-	NC_000007.14:g.87539294T>C	ExAC,gnomAD
rs1216670269	p.Val792Ile	missense variant	-	NC_000007.14:g.87539291C>T	TOPMed
rs201249149	p.Arg794Gln	missense variant	-	NC_000007.14:g.87539284C>T	ExAC,TOPMed,gnomAD
rs201249149	p.Arg794Leu	missense variant	-	NC_000007.14:g.87539284C>A	ExAC,TOPMed,gnomAD
rs201418528	p.Ser795Cys	missense variant	-	NC_000007.14:g.87539281G>C	1000Genomes,ExAC,TOPMed,gnomAD
rs766867299	p.Ser795Thr	missense variant	-	NC_000007.14:g.87539282A>T	ExAC,gnomAD
rs766867299	p.Ser795Pro	missense variant	-	NC_000007.14:g.87539282A>G	ExAC,gnomAD
rs751041906	p.Leu797Ile	missense variant	-	NC_000007.14:g.87539276G>T	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Gln799His	missense variant	-	NC_000007.14:g.87539268C>A	NCI-TCGA
NCI-TCGA novel	p.Asp800Tyr	missense variant	-	NC_000007.14:g.87536541C>A	NCI-TCGA
rs201142514	p.Asp800Glu	missense variant	-	NC_000007.14:g.87536539A>T	ExAC,gnomAD
NCI-TCGA novel	p.Val801Ala	missense variant	-	NC_000007.14:g.87536537A>G	NCI-TCGA
rs2235039	p.Val801Met	missense variant	-	NC_000007.14:g.87536538C>T	UniProt,dbSNP
VAR_055428	p.Val801Met	missense variant	-	NC_000007.14:g.87536538C>T	UniProt
rs2235039	p.Val801Met	missense variant	-	NC_000007.14:g.87536538C>T	-
COSM1092608	p.Asp805Asn	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87536526C>T	NCI-TCGA Cosmic
COSM1313359	p.Asp805Tyr	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87536526C>A	NCI-TCGA Cosmic
COSM3784091	p.Asp806Asn	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87536523C>T	NCI-TCGA Cosmic
COSM5139801	p.Asn809ThrPheSerTerUnk	frameshift	Variant assessed as Somatic; HIGH impact.	NC_000007.14:g.87536513T>-	NCI-TCGA Cosmic
COSM3883058	p.Gly812Glu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87536504C>T	NCI-TCGA Cosmic
rs764059820	p.Gly812Arg	missense variant	-	NC_000007.14:g.87536505C>T	TOPMed
rs201744003	p.Ala813Gly	missense variant	-	NC_000007.14:g.87536501G>C	ESP,ExAC,TOPMed,gnomAD
rs201744003	p.Ala813Val	missense variant	-	NC_000007.14:g.87536501G>A	ESP,ExAC,TOPMed,gnomAD
rs200754866	p.Ala819Thr	missense variant	-	NC_000007.14:g.87536484C>T	1000Genomes,ExAC,TOPMed,gnomAD
rs200754866	p.Ala819Ser	missense variant	-	NC_000007.14:g.87536484C>A	1000Genomes,ExAC,TOPMed,gnomAD
rs1334428451	p.Asp821Gly	missense variant	-	NC_000007.14:g.87536477T>C	TOPMed
rs1289543302	p.Ala823Thr	missense variant	-	NC_000007.14:g.87536472C>T	TOPMed
NCI-TCGA novel	p.Gln824Glu	missense variant	-	NC_000007.14:g.87536469G>C	NCI-TCGA
rs1455293604	p.Gly827Glu	missense variant	-	NC_000007.14:g.87536459C>T	gnomAD
rs2032581	p.Ile829Val	missense variant	-	NC_000007.14:g.87531494T>C	gnomAD
rs2032581	p.Ile829Val	missense variant	-	NC_000007.14:g.87531494T>C	UniProt,dbSNP
VAR_055429	p.Ile829Val	missense variant	-	NC_000007.14:g.87531494T>C	UniProt
rs767089531	p.Gly830Val	missense variant	-	NC_000007.14:g.87531490C>A	ExAC,TOPMed,gnomAD
rs767089531	p.Gly830Asp	missense variant	-	NC_000007.14:g.87531490C>T	ExAC,TOPMed,gnomAD
rs1199081702	p.Gly830Ser	missense variant	-	NC_000007.14:g.87531491C>T	TOPMed
rs1280076381	p.Leu833Phe	missense variant	-	NC_000007.14:g.87531482G>A	TOPMed,gnomAD
NCI-TCGA novel	p.Leu833Pro	missense variant	-	NC_000007.14:g.87531481A>G	NCI-TCGA
rs1280076381	p.Leu833Val	missense variant	-	NC_000007.14:g.87531482G>C	TOPMed,gnomAD
COSM6178504	p.Ala834Val	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87531478G>A	NCI-TCGA Cosmic
rs28381967	p.Ile836Val	missense variant	-	NC_000007.14:g.87531473T>C	1000Genomes,ESP,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Thr837Ile	missense variant	-	NC_000007.14:g.87531469G>A	NCI-TCGA
rs762765487	p.Thr837Ala	missense variant	-	NC_000007.14:g.87531470T>C	ExAC,gnomAD
rs773262840	p.Asn839Ser	missense variant	-	NC_000007.14:g.87531463T>C	ExAC,gnomAD
rs773262840	p.Asn839Thr	missense variant	-	NC_000007.14:g.87531463T>G	ExAC,gnomAD
COSM1452579	p.Ala841Thr	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87531458C>T	NCI-TCGA Cosmic
rs1416566507	p.Ala841Glu	missense variant	-	NC_000007.14:g.87531457G>T	gnomAD
NCI-TCGA novel	p.Asn842His	missense variant	-	NC_000007.14:g.87531455T>G	NCI-TCGA
NCI-TCGA novel	p.Leu843Ile	missense variant	-	NC_000007.14:g.87531452G>T	NCI-TCGA
COSM1243950	p.Leu843Arg	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87531451A>C	NCI-TCGA Cosmic
rs1191107366	p.Gly846Arg	missense variant	-	NC_000007.14:g.87531443C>T	TOPMed
rs773175021	p.Gly846Glu	missense variant	-	NC_000007.14:g.87531442C>T	gnomAD
rs1432480917	p.Ile847Val	missense variant	-	NC_000007.14:g.87531440T>C	gnomAD
NCI-TCGA novel	p.Ile848Ser	missense variant	-	NC_000007.14:g.87531436A>C	NCI-TCGA
rs36105130	p.Ile849Met	missense variant	-	NC_000007.14:g.87531432T>C	-
COSM3641913	p.Ser850Phe	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87531430G>A	NCI-TCGA Cosmic
rs1158620384	p.Phe851Tyr	missense variant	-	NC_000007.14:g.87531427A>T	gnomAD
rs747022752	p.Ile852Met	missense variant	-	NC_000007.14:g.87531423G>C	ExAC,TOPMed,gnomAD
rs557586335	p.Tyr853Asn	missense variant	-	NC_000007.14:g.87531422A>T	1000Genomes
rs371274259	p.Tyr853Cys	missense variant	-	NC_000007.14:g.87531421T>C	ESP,ExAC,TOPMed,gnomAD
rs746152564	p.Trp855Ter	stop gained	-	NC_000007.14:g.87531415C>T	ExAC,gnomAD
COSM3883057	p.Gln856Ter	stop gained	Variant assessed as Somatic; HIGH impact.	NC_000007.14:g.87531413G>A	NCI-TCGA Cosmic
COSM3883056	p.Leu859Arg	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87531403A>C	NCI-TCGA Cosmic
NCI-TCGA novel	p.Leu861Ile	missense variant	-	NC_000007.14:g.87531398G>T	NCI-TCGA
rs1000911090	p.Leu861Pro	missense variant	-	NC_000007.14:g.87531397A>G	TOPMed
rs1295312177	p.Leu862Ser	missense variant	-	NC_000007.14:g.87531394A>G	TOPMed
rs749745819	p.Ile864Thr	missense variant	-	NC_000007.14:g.87531388A>G	ExAC,gnomAD
rs539556127	p.Ile864Val	missense variant	-	NC_000007.14:g.87531389T>C	1000Genomes,ExAC,gnomAD
rs778283893	p.Pro866Ser	missense variant	-	NC_000007.14:g.87531383G>A	ExAC
rs1380560733	p.Ile867Met	missense variant	-	NC_000007.14:g.87531378G>C	TOPMed
NCI-TCGA novel	p.Ile870ArgLys	insertion	-	NC_000007.14:g.87531368_87531369insCTTCCT	NCI-TCGA
NCI-TCGA novel	p.Ala871Glu	missense variant	-	NC_000007.14:g.87531367G>T	NCI-TCGA
COSM1092606	p.Gly872Val	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87531364C>A	NCI-TCGA Cosmic
rs565619660	p.Val874Ala	missense variant	-	NC_000007.14:g.87531358A>G	1000Genomes,ExAC,gnomAD
rs1356091019	p.Met878Leu	missense variant	-	NC_000007.14:g.87531347T>A	gnomAD
NCI-TCGA novel	p.Gly881Val	missense variant	-	NC_000007.14:g.87531337C>A	NCI-TCGA
rs1325417202	p.Gln882Glu	missense variant	-	NC_000007.14:g.87531335G>C	gnomAD
COSM3883055	p.Gln882Arg	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87531334T>C	NCI-TCGA Cosmic
rs147823195	p.Ala883Ser	missense variant	-	NC_000007.14:g.87531332C>A	ESP,ExAC,gnomAD
rs147823195	p.Ala883Thr	missense variant	-	NC_000007.14:g.87531332C>T	ESP,ExAC,gnomAD
rs375296280	p.Leu884Pro	missense variant	-	NC_000007.14:g.87531328A>G	ESP,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Lys885Asn	missense variant	-	NC_000007.14:g.87531324T>G	NCI-TCGA
rs1292455657	p.Asp886Asn	missense variant	-	NC_000007.14:g.87531323C>T	TOPMed
NCI-TCGA novel	p.Lys887Met	missense variant	-	NC_000007.14:g.87531319T>A	NCI-TCGA
COSM1568835	p.Lys887Glu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87531320T>C	NCI-TCGA Cosmic
VAR_035737	p.Lys887Asn	Missense	-	-	UniProt
COSM3883054	p.Glu889Ter	stop gained	Variant assessed as Somatic; HIGH impact.	NC_000007.14:g.87531314C>A	NCI-TCGA Cosmic
NCI-TCGA novel	p.Glu891Lys	missense variant	-	NC_000007.14:g.87531308C>T	NCI-TCGA
COSM1092605	p.Gly892Cys	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87531305C>A	NCI-TCGA Cosmic
RCV000429867	p.Ser893Thr	missense variant	Ovarian Neoplasms	NC_000007.14:g.87531302A>T	ClinVar
RCV000211425	p.Ser893Ala	missense variant	-	NC_000007.14:g.87531302A>C	ClinVar
RCV000211207	p.Ser893Ala	missense variant	-	NC_000007.14:g.87531302A>C	ClinVar
rs2032582	p.Ser893Thr	missense variant	-	NC_000007.14:g.87531302A>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs2032582	p.Ser893Thr	missense variant	-	NC_000007.14:g.87531302A>T	UniProt,dbSNP
VAR_013362	p.Ser893Thr	missense variant	-	NC_000007.14:g.87531302A>T	UniProt
rs2032582	p.Ser893Ala	missense variant	-	NC_000007.14:g.87531302A>C	UniProt,dbSNP
VAR_013361	p.Ser893Ala	missense variant	-	NC_000007.14:g.87531302A>C	UniProt
rs2032582	p.Ser893Ala	missense variant	-	NC_000007.14:g.87531302A>C	1000Genomes,ESP,ExAC,TOPMed,gnomAD
COSM360322	p.Gly894Ala	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87531298C>G	NCI-TCGA Cosmic
rs772319458	p.Gly894Arg	missense variant	-	NC_000007.14:g.87531299C>T	ExAC,gnomAD
COSM6110889	p.Lys895Met	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87531295T>A	NCI-TCGA Cosmic
rs532094830	p.Ile896Met	missense variant	-	NC_000007.14:g.87520874G>C	1000Genomes,ExAC,TOPMed,gnomAD
rs1219195402	p.Ile896Asn	missense variant	-	NC_000007.14:g.87520875A>T	gnomAD
rs147487745	p.Ala897Thr	missense variant	-	NC_000007.14:g.87520873C>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs767693167	p.Thr898Ala	missense variant	-	NC_000007.14:g.87520870T>C	ExAC,TOPMed,gnomAD
COSM747740	p.Glu899Lys	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87520867C>T	NCI-TCGA Cosmic
rs138472105	p.Ala900Thr	missense variant	-	NC_000007.14:g.87520864C>T	1000Genomes,gnomAD
rs1305120399	p.Ile901Thr	missense variant	-	NC_000007.14:g.87520860A>G	TOPMed,gnomAD
rs1441208915	p.Ile901Met	missense variant	-	NC_000007.14:g.87520859T>C	gnomAD
NCI-TCGA novel	p.Glu902Ter	stop gained	-	NC_000007.14:g.87520858C>A	NCI-TCGA
NCI-TCGA novel	p.Phe904Val	missense variant	-	NC_000007.14:g.87520852A>C	NCI-TCGA
rs1244089186	p.Phe904Ser	missense variant	-	NC_000007.14:g.87520851A>G	TOPMed
rs774299788	p.Arg905Gln	missense variant	-	NC_000007.14:g.87520848C>T	ExAC,TOPMed,gnomAD
rs759603974	p.Arg905Ter	stop gained	-	NC_000007.14:g.87520849G>A	ExAC,gnomAD
COSM747741	p.Thr906Asn	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87520845G>T	NCI-TCGA Cosmic
rs573245329	p.Val907Ile	missense variant	-	NC_000007.14:g.87520843C>T	1000Genomes,ExAC,TOPMed,gnomAD
rs573245329	p.Val907Phe	missense variant	-	NC_000007.14:g.87520843C>A	1000Genomes,ExAC,TOPMed,gnomAD
COSM4825526	p.Gln912Glu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87520828G>C	NCI-TCGA Cosmic
rs773542500	p.Glu913Lys	missense variant	-	NC_000007.14:g.87520825C>T	ExAC,gnomAD
NCI-TCGA novel	p.Gln914Leu	missense variant	-	NC_000007.14:g.87520821T>A	NCI-TCGA
COSM1313358	p.Gln914His	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87520820C>A	NCI-TCGA Cosmic
rs770181793	p.Lys915Asn	missense variant	-	NC_000007.14:g.87520817C>A	ExAC,gnomAD
rs1234949048	p.Lys915Thr	missense variant	-	NC_000007.14:g.87520818T>G	gnomAD
NCI-TCGA novel	p.His918Asn	missense variant	-	NC_000007.14:g.87520810G>T	NCI-TCGA
rs748646739	p.His918Tyr	missense variant	-	NC_000007.14:g.87520810G>A	ExAC,gnomAD
NCI-TCGA novel	p.Met919Arg	missense variant	-	NC_000007.14:g.87520806A>C	NCI-TCGA
rs201740660	p.Met919Thr	missense variant	-	NC_000007.14:g.87520806A>G	ExAC,TOPMed,gnomAD
rs201740660	p.Met919Lys	missense variant	-	NC_000007.14:g.87520806A>T	ExAC,TOPMed,gnomAD
rs1481562306	p.Ser923Arg	missense variant	-	NC_000007.14:g.87520793A>T	gnomAD
rs377518806	p.Ser923Asn	missense variant	-	NC_000007.14:g.87520794C>T	ESP,gnomAD
rs377518806	p.Ser923Ile	missense variant	-	NC_000007.14:g.87520794C>A	ESP,gnomAD
rs746491990	p.Gln925Lys	missense variant	-	NC_000007.14:g.87520789G>T	ExAC,gnomAD
rs201316099	p.Val926Leu	missense variant	-	NC_000007.14:g.87520786C>G	ExAC,TOPMed,gnomAD
rs201316099	p.Val926Ile	missense variant	-	NC_000007.14:g.87520786C>T	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Pro927Ser	missense variant	-	NC_000007.14:g.87520783G>A	NCI-TCGA
rs148718120	p.Tyr928Ser	missense variant	-	NC_000007.14:g.87520779T>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Arg929Ile	missense variant	-	NC_000007.14:g.87520776C>A	NCI-TCGA
rs1233953132	p.Asn930His	missense variant	-	NC_000007.14:g.87519465T>G	gnomAD
rs749050513	p.Leu932Ser	missense variant	-	NC_000007.14:g.87519458A>G	ExAC,gnomAD
rs1290803512	p.Lys934Arg	missense variant	-	NC_000007.14:g.87519452T>C	gnomAD
rs200811596	p.Ile937Leu	missense variant	-	NC_000007.14:g.87519444T>G	1000Genomes,ExAC,gnomAD
COSM453507	p.Gly939Ala	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87519437C>G	NCI-TCGA Cosmic
rs1157098297	p.Gly939Arg	missense variant	-	NC_000007.14:g.87519438C>T	gnomAD
rs1455566610	p.Thr941Ile	missense variant	-	NC_000007.14:g.87519431G>A	TOPMed,gnomAD
NCI-TCGA novel	p.Ser943Tyr	missense variant	-	NC_000007.14:g.87519425G>T	NCI-TCGA
COSM3641911	p.Ser943Phe	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87519425G>A	NCI-TCGA Cosmic
rs1489594324	p.Phe944Ser	missense variant	-	NC_000007.14:g.87519422A>G	TOPMed
rs766473800	p.Thr945Ile	missense variant	-	NC_000007.14:g.87519419G>A	ExAC,gnomAD
rs750510915	p.Ala947Ser	missense variant	-	NC_000007.14:g.87519414C>A	ExAC,TOPMed,gnomAD
rs1253848627	p.Met948Val	missense variant	-	NC_000007.14:g.87519411T>C	gnomAD
rs765372820	p.Met948Thr	missense variant	-	NC_000007.14:g.87519410A>G	ExAC,gnomAD
rs1486026524	p.Tyr950Cys	missense variant	-	NC_000007.14:g.87519404T>C	gnomAD
NCI-TCGA novel	p.Phe951SerPheSerTerUnk	stop gained	-	NC_000007.14:g.87519401_87519402insCCCTACTGTG	NCI-TCGA
rs1259613365	p.Ser952Thr	missense variant	-	NC_000007.14:g.87519399A>T	gnomAD
COSM231681	p.Ser952Phe	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87519398G>A	NCI-TCGA Cosmic
rs371370057	p.Tyr953His	missense variant	-	NC_000007.14:g.87519396A>G	ESP,ExAC,TOPMed,gnomAD
rs764408569	p.Tyr953Cys	missense variant	-	NC_000007.14:g.87519395T>C	ExAC,gnomAD
NCI-TCGA novel	p.Gly955Ter	stop gained	-	NC_000007.14:g.87519390C>A	NCI-TCGA
rs201357626	p.Cys956Tyr	missense variant	-	NC_000007.14:g.87519386C>T	gnomAD
rs200280095	p.Arg958Trp	missense variant	-	NC_000007.14:g.87519381G>A	ExAC,TOPMed,gnomAD
rs144369247	p.Arg958Gln	missense variant	-	NC_000007.14:g.87519380C>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
COSM3641910	p.Gly960Glu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87519374C>T	NCI-TCGA Cosmic
NCI-TCGA novel	p.Ala961Val	missense variant	-	NC_000007.14:g.87519371G>A	NCI-TCGA
COSM5408175	p.Ala961Thr	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87519372C>T	NCI-TCGA Cosmic
rs759050765	p.Leu963Phe	missense variant	-	NC_000007.14:g.87519364C>A	ExAC,gnomAD
COSM4922438	p.Leu963Trp	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87519365A>C	NCI-TCGA Cosmic
rs1395355925	p.Leu963Ser	missense variant	-	NC_000007.14:g.87519365A>G	gnomAD
rs1457360738	p.Val964Met	missense variant	-	NC_000007.14:g.87519363C>T	TOPMed,gnomAD
NCI-TCGA novel	p.Glu972Gln	missense variant	-	NC_000007.14:g.87519339C>G	NCI-TCGA
rs770657790	p.Glu972Lys	missense variant	-	NC_000007.14:g.87519339C>T	ExAC,gnomAD
rs748995428	p.Asp973Tyr	missense variant	-	NC_000007.14:g.87519336C>A	ExAC,gnomAD
rs748995428	p.Asp973Asn	missense variant	-	NC_000007.14:g.87519336C>T	ExAC,gnomAD
rs149638669	p.Asp973Ala	missense variant	-	NC_000007.14:g.87519335T>G	ESP,gnomAD
COSM1092604	p.Val974Phe	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87519333C>A	NCI-TCGA Cosmic
rs777591929	p.Val974Ile	missense variant	-	NC_000007.14:g.87519333C>T	ExAC,gnomAD
rs781068922	p.Phe978Ile	missense variant	-	NC_000007.14:g.87516661A>T	ExAC,gnomAD
COSM3641909	p.Ser979Leu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87516657G>A	NCI-TCGA Cosmic
rs572038993	p.Ala980Pro	missense variant	-	NC_000007.14:g.87516655C>G	1000Genomes,ExAC,gnomAD
rs746992715	p.Phe983Leu	missense variant	-	NC_000007.14:g.87516646A>G	ExAC,gnomAD
rs1441051651	p.Phe983Ser	missense variant	-	NC_000007.14:g.87516645A>G	TOPMed
rs1306027704	p.Ala985Gly	missense variant	-	NC_000007.14:g.87516639G>C	gnomAD
rs1269015981	p.Met986Thr	missense variant	-	NC_000007.14:g.87516636A>G	TOPMed
rs778961519	p.Met986Ile	missense variant	-	NC_000007.14:g.87516635C>T	ExAC,gnomAD
NCI-TCGA novel	p.Ala987Thr	missense variant	-	NC_000007.14:g.87516634C>T	NCI-TCGA
rs1359447217	p.Ala987Val	missense variant	-	NC_000007.14:g.87516633G>A	TOPMed
rs753967146	p.Val988Met	missense variant	-	NC_000007.14:g.87516631C>T	ExAC,TOPMed,gnomAD
COSM453506	p.Gly989Glu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87516627C>T	NCI-TCGA Cosmic
rs374210543	p.Gly989Val	missense variant	-	NC_000007.14:g.87516627C>A	ESP,ExAC,gnomAD
rs56849127	p.Ser992Asn	missense variant	-	NC_000007.14:g.87516618C>T	gnomAD
rs56849127	p.Ser992Ile	missense variant	-	NC_000007.14:g.87516618C>A	gnomAD
NCI-TCGA novel	p.Ser993Ala	missense variant	-	NC_000007.14:g.87516616A>C	NCI-TCGA
rs756391728	p.Tyr998Ser	missense variant	-	NC_000007.14:g.87516600T>G	ExAC,gnomAD
rs72552784	p.Ala999Thr	missense variant	-	NC_000007.14:g.87516598C>T	TOPMed
rs72552784	p.Ala999Thr	missense variant	-	NC_000007.14:g.87516598C>T	UniProt,dbSNP
VAR_015004	p.Ala999Thr	missense variant	-	NC_000007.14:g.87516598C>T	UniProt
rs72552784	p.Ala999Ser	missense variant	-	NC_000007.14:g.87516598C>A	TOPMed
rs1213524837	p.Ala1001Thr	missense variant	-	NC_000007.14:g.87516592C>T	gnomAD
rs752955240	p.Ala1001Gly	missense variant	-	NC_000007.14:g.87516591G>C	ExAC,gnomAD
NCI-TCGA novel	p.Ser1004Leu	missense variant	-	NC_000007.14:g.87516582G>A	NCI-TCGA
NCI-TCGA novel	p.His1007Leu	missense variant	-	NC_000007.14:g.87516573T>A	NCI-TCGA
rs1279830740	p.His1007Arg	missense variant	-	NC_000007.14:g.87516573T>C	gnomAD
rs201974955	p.Met1010Val	missense variant	-	NC_000007.14:g.87516565T>C	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Ile1011Val	missense variant	-	NC_000007.14:g.87516562T>C	NCI-TCGA
rs1239674801	p.Ile1011Phe	missense variant	-	NC_000007.14:g.87516562T>A	gnomAD
rs765970394	p.Glu1013Asp	missense variant	-	NC_000007.14:g.87516554T>A	ExAC,gnomAD
rs145774816	p.Thr1015Asn	missense variant	-	NC_000007.14:g.87516549G>T	ESP,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Thr1015ProPheSerTerUnk	frameshift	-	NC_000007.14:g.87516550T>-	NCI-TCGA
NCI-TCGA novel	p.Thr1015AsnPheSerTerUnk	frameshift	-	NC_000007.14:g.87516549_87516550insT	NCI-TCGA
COSM1452578	p.Thr1015Ser	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87516550T>A	NCI-TCGA Cosmic
NCI-TCGA novel	p.Pro1016LeuPheSerTerUnk	frameshift	-	NC_000007.14:g.87516546G>-	NCI-TCGA
COSM3032638	p.Pro1016Ser	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87516547G>A	NCI-TCGA Cosmic
rs1355889810	p.Pro1016Arg	missense variant	-	NC_000007.14:g.87516546G>C	TOPMed,gnomAD
rs1327938429	p.Asp1019Glu	missense variant	-	NC_000007.14:g.87516536G>T	TOPMed,gnomAD
rs772778438	p.Asp1019Asn	missense variant	-	NC_000007.14:g.87516538C>T	ExAC,gnomAD
COSM6178507	p.Asp1019Tyr	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87516538C>A	NCI-TCGA Cosmic
rs1386411918	p.Ser1022Gly	missense variant	-	NC_000007.14:g.87516529T>C	TOPMed,gnomAD
rs1158715642	p.Ser1022Arg	missense variant	-	NC_000007.14:g.87516527G>T	gnomAD
rs1386411918	p.Ser1022Arg	missense variant	-	NC_000007.14:g.87516529T>G	TOPMed,gnomAD
NCI-TCGA novel	p.Ser1022Ile	missense variant	-	NC_000007.14:g.87516528C>A	NCI-TCGA
rs142183184	p.Thr1023Met	missense variant	-	NC_000007.14:g.87516525G>A	ESP,ExAC,TOPMed,gnomAD
rs1162482512	p.Thr1023Ala	missense variant	-	NC_000007.14:g.87516526T>C	TOPMed
rs1317094548	p.Gly1025Ser	missense variant	-	NC_000007.14:g.87516520C>T	TOPMed
COSM6178508	p.Gly1025Cys	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87516520C>A	NCI-TCGA Cosmic
rs768507751	p.Gly1025Ala	missense variant	-	NC_000007.14:g.87516519C>G	ExAC,gnomAD
rs768507751	p.Gly1025Asp	missense variant	-	NC_000007.14:g.87516519C>T	ExAC,gnomAD
rs553790901	p.Met1027Leu	missense variant	-	NC_000007.14:g.87516514T>A	1000Genomes,ExAC,gnomAD
rs199819428	p.Met1027Thr	missense variant	-	NC_000007.14:g.87516513A>G	ExAC,TOPMed,gnomAD
rs199819428	p.Met1027Lys	missense variant	-	NC_000007.14:g.87516513A>T	ExAC,TOPMed,gnomAD
rs371977867	p.Pro1028Leu	missense variant	-	NC_000007.14:g.87516510G>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1432511771	p.Pro1028Ser	missense variant	-	NC_000007.14:g.87516511G>A	TOPMed
rs771856280	p.Asn1029Ser	missense variant	-	NC_000007.14:g.87515427T>C	ExAC,TOPMed,gnomAD
rs201542635	p.Thr1030Ala	missense variant	-	NC_000007.14:g.87515425T>C	TOPMed
rs745866303	p.Leu1031Ser	missense variant	-	NC_000007.14:g.87515421A>G	ExAC,gnomAD
rs769980649	p.Glu1032Gly	missense variant	-	NC_000007.14:g.87515418T>C	ExAC,gnomAD
NCI-TCGA novel	p.Val1035Ala	missense variant	-	NC_000007.14:g.87515409A>G	NCI-TCGA
rs896954671	p.Thr1036Lys	missense variant	-	NC_000007.14:g.87515406G>T	gnomAD
rs896954671	p.Thr1036Ile	missense variant	-	NC_000007.14:g.87515406G>A	gnomAD
rs781503569	p.Phe1037Leu	missense variant	-	NC_000007.14:g.87515402A>T	ExAC,TOPMed,gnomAD
rs201819590	p.Val1040Ala	missense variant	-	NC_000007.14:g.87515394A>G	ExAC,gnomAD
rs200968469	p.Val1041Ile	missense variant	-	NC_000007.14:g.87515392C>T	ExAC,gnomAD
rs780583874	p.Tyr1044Phe	missense variant	-	NC_000007.14:g.87515382T>A	ExAC,gnomAD
rs957765239	p.Pro1045Thr	missense variant	-	NC_000007.14:g.87515380G>T	TOPMed,gnomAD
rs957765239	p.Pro1045Ala	missense variant	-	NC_000007.14:g.87515380G>C	TOPMed,gnomAD
rs1439277801	p.Thr1046Ile	missense variant	-	NC_000007.14:g.87515376G>A	gnomAD
rs758803493	p.Thr1046Pro	missense variant	-	NC_000007.14:g.87515377T>G	ExAC,gnomAD
rs751009298	p.Arg1047Ter	stop gained	-	NC_000007.14:g.87515374G>A	ExAC,TOPMed,gnomAD
rs778275248	p.Pro1048Ser	missense variant	-	NC_000007.14:g.87515371G>A	ExAC,TOPMed,gnomAD
rs756736504	p.Pro1048Leu	missense variant	-	NC_000007.14:g.87515370G>A	ExAC,TOPMed,gnomAD
rs760344941	p.Ile1050Leu	missense variant	-	NC_000007.14:g.87515365T>G	ExAC,TOPMed,gnomAD
rs760344941	p.Ile1050Phe	missense variant	-	NC_000007.14:g.87515365T>A	ExAC,TOPMed,gnomAD
rs28401798	p.Pro1051Ala	missense variant	-	NC_000007.14:g.87515362G>C	UniProt,dbSNP
VAR_022280	p.Pro1051Ala	missense variant	-	NC_000007.14:g.87515362G>C	UniProt
rs28401798	p.Pro1051Ala	missense variant	-	NC_000007.14:g.87515362G>C	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1370593595	p.Val1052Ala	missense variant	-	NC_000007.14:g.87515358A>G	gnomAD
rs1409934524	p.Leu1053Pro	missense variant	-	NC_000007.14:g.87515355A>G	TOPMed
NCI-TCGA novel	p.Gln1054His	missense variant	-	NC_000007.14:g.87515351C>A	NCI-TCGA
COSM3950898	p.Gly1055Ter	stop gained	Variant assessed as Somatic; HIGH impact.	NC_000007.14:g.87515350C>A	NCI-TCGA Cosmic
rs774405049	p.Gly1055Glu	missense variant	-	NC_000007.14:g.87515349C>T	ExAC,TOPMed,gnomAD
rs199891187	p.Gly1055Arg	missense variant	-	NC_000007.14:g.87515350C>T	ExAC,TOPMed,gnomAD
rs770785509	p.Ser1057Arg	missense variant	-	NC_000007.14:g.87515342G>T	ExAC,gnomAD
rs1447617813	p.Leu1058Val	missense variant	-	NC_000007.14:g.87515341G>C	TOPMed
rs1377559224	p.Glu1059Ter	stop gained	-	NC_000007.14:g.87515338C>A	gnomAD
NCI-TCGA novel	p.Glu1059Lys	missense variant	-	NC_000007.14:g.87515338C>T	NCI-TCGA
rs1235695290	p.Lys1061Asn	missense variant	-	NC_000007.14:g.87515330C>A	TOPMed
rs1369130405	p.Lys1061Arg	missense variant	-	NC_000007.14:g.87515331T>C	TOPMed
rs1432613672	p.Lys1062Asn	missense variant	-	NC_000007.14:g.87515327C>A	gnomAD
rs761914266	p.Gly1063Cys	missense variant	-	NC_000007.14:g.87515326C>A	ExAC,gnomAD
NCI-TCGA novel	p.Gln1064His	missense variant	-	NC_000007.14:g.87515321C>A	NCI-TCGA
rs776877163	p.Thr1065Met	missense variant	-	NC_000007.14:g.87515319G>A	ExAC,TOPMed,gnomAD
rs780279896	p.Ala1067Asp	missense variant	-	NC_000007.14:g.87515313G>T	ExAC,TOPMed,gnomAD
rs201951511	p.Ala1067Thr	missense variant	-	NC_000007.14:g.87515314C>T	ExAC,gnomAD
rs780279896	p.Ala1067Val	missense variant	-	NC_000007.14:g.87515313G>A	ExAC,TOPMed,gnomAD
rs772547356	p.Leu1068Val	missense variant	-	NC_000007.14:g.87515311G>C	ExAC,gnomAD
COSM1330486	p.Ser1071Arg	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87515300G>T	NCI-TCGA Cosmic
rs1433103757	p.Ser1072Asn	missense variant	-	NC_000007.14:g.87515298C>T	TOPMed,gnomAD
rs1198742227	p.Gly1073Ala	missense variant	-	NC_000007.14:g.87515295C>G	TOPMed
rs1025622951	p.Cys1074Tyr	missense variant	-	NC_000007.14:g.87515292C>T	TOPMed,gnomAD
NCI-TCGA novel	p.Cys1074Phe	missense variant	-	NC_000007.14:g.87515292C>A	NCI-TCGA
rs746235474	p.Cys1074Trp	missense variant	-	NC_000007.14:g.87515291A>C	ExAC,gnomAD
NCI-TCGA novel	p.Lys1076ArgPheSerTerUnkUnk	frameshift	-	NC_000007.14:g.87515286_87515287insC	NCI-TCGA
COSM6110890	p.Ser1077Arg	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87515282G>T	NCI-TCGA Cosmic
rs1431158619	p.Ser1077Asn	missense variant	-	NC_000007.14:g.87515283C>T	TOPMed
rs200192869	p.Thr1078Ala	missense variant	-	NC_000007.14:g.87515281T>C	ExAC,TOPMed,gnomAD
rs200192869	p.Thr1078Ser	missense variant	-	NC_000007.14:g.87515281T>A	ExAC,TOPMed,gnomAD
rs200192869	p.Thr1078Pro	missense variant	-	NC_000007.14:g.87515281T>G	ExAC,TOPMed,gnomAD
rs1377795423	p.Val1079Met	missense variant	-	NC_000007.14:g.87515278C>T	TOPMed
rs1475311087	p.Val1080Ile	missense variant	-	NC_000007.14:g.87515275C>T	TOPMed
rs1288076350	p.Val1080Ala	missense variant	-	NC_000007.14:g.87515274A>G	gnomAD
rs1288076350	p.Val1080Gly	missense variant	-	NC_000007.14:g.87515274A>C	gnomAD
rs200514028	p.Leu1083Val	missense variant	-	NC_000007.14:g.87515266G>C	ExAC,TOPMed,gnomAD
rs755734139	p.Leu1083Pro	missense variant	-	NC_000007.14:g.87515265A>G	ExAC,gnomAD
rs1403103790	p.Glu1084Gln	missense variant	-	NC_000007.14:g.87515263C>G	TOPMed
rs199943026	p.Arg1085Trp	missense variant	-	NC_000007.14:g.87515260G>A	ExAC,gnomAD
rs201765972	p.Arg1085Gln	missense variant	-	NC_000007.14:g.87515259C>T	ESP,ExAC,gnomAD
rs57521326	p.Asp1088Asn	missense variant	-	NC_000007.14:g.87515251C>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1412681422	p.Ala1091Gly	missense variant	-	NC_000007.14:g.87515241G>C	gnomAD
rs776827328	p.Lys1093Glu	missense variant	-	NC_000007.14:g.87515236T>C	ExAC,gnomAD
rs768927661	p.Val1094Met	missense variant	-	NC_000007.14:g.87515233C>T	ExAC,gnomAD
NCI-TCGA novel	p.Asp1097Tyr	missense variant	-	NC_000007.14:g.87509475C>A	NCI-TCGA
rs41309225	p.Lys1099Glu	missense variant	-	NC_000007.14:g.87509469T>C	ExAC,gnomAD
rs41309225	p.Lys1099Gln	missense variant	-	NC_000007.14:g.87509469T>G	ExAC,gnomAD
NCI-TCGA novel	p.Glu1100Ter	stop gained	-	NC_000007.14:g.87509466C>A	NCI-TCGA
COSM3641905	p.Ile1101Leu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87509463T>A	NCI-TCGA Cosmic
rs1266372866	p.Arg1103Gln	missense variant	-	NC_000007.14:g.87509456C>T	gnomAD
rs1470273650	p.Arg1103Ter	stop gained	-	NC_000007.14:g.87509457G>A	gnomAD
rs148897157	p.Val1106Ile	missense variant	-	NC_000007.14:g.87509448C>T	ESP,ExAC,TOPMed,gnomAD
rs55852620	p.Gln1107Pro	missense variant	-	NC_000007.14:g.87509444T>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs55852620	p.Gln1107Pro	missense variant	-	NC_000007.14:g.87509444T>G	UniProt,dbSNP
VAR_015005	p.Gln1107Pro	missense variant	-	NC_000007.14:g.87509444T>G	UniProt
rs774748307	p.Gln1107Glu	missense variant	-	NC_000007.14:g.87509445G>C	ExAC,TOPMed,gnomAD
rs35730308	p.Trp1108Arg	missense variant	-	NC_000007.14:g.87509442A>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1334153891	p.Trp1108Ter	stop gained	-	NC_000007.14:g.87509441C>T	TOPMed
rs773651038	p.Leu1109Ile	missense variant	-	NC_000007.14:g.87509439G>T	ExAC,gnomAD
rs1014207158	p.Arg1110Ter	stop gained	-	NC_000007.14:g.87509436G>A	TOPMed
rs770289924	p.Arg1110Gln	missense variant	-	NC_000007.14:g.87509435C>T	ExAC,TOPMed,gnomAD
rs1293871816	p.Ala1111Thr	missense variant	-	NC_000007.14:g.87509433C>T	TOPMed,gnomAD
NCI-TCGA novel	p.Leu1113Met	missense variant	-	NC_000007.14:g.87509427G>T	NCI-TCGA
NCI-TCGA novel	p.Gly1114AlaPheSerTerUnkUnk	frameshift	-	NC_000007.14:g.87509423C>-	NCI-TCGA
rs747650743	p.Gly1114Ser	missense variant	-	NC_000007.14:g.87509424C>T	ExAC,gnomAD
rs1328523726	p.Gly1114Asp	missense variant	-	NC_000007.14:g.87509423C>T	TOPMed
rs199931681	p.Ile1115Thr	missense variant	-	NC_000007.14:g.87509420A>G	TOPMed,gnomAD
NCI-TCGA novel	p.Ile1115SerHisLysThrSer	insertion	-	NC_000007.14:g.87509418_87509419insAGATGTCTTGTGGGA	NCI-TCGA
rs1347910274	p.Ile1115Val	missense variant	-	NC_000007.14:g.87509421T>C	gnomAD
rs1389010033	p.Val1116Met	missense variant	-	NC_000007.14:g.87509418C>T	TOPMed,gnomAD
NCI-TCGA novel	p.Val1116SerPheSerTerUnkUnk	frameshift	-	NC_000007.14:g.87509418_87509419insAGATGTCTTGTGGGAGA	NCI-TCGA
rs746677023	p.Pro1120His	missense variant	-	NC_000007.14:g.87509405G>T	ExAC,gnomAD
rs1017877229	p.Ile1121Met	missense variant	-	NC_000007.14:g.87509401G>C	TOPMed
NCI-TCGA novel	p.Leu1122Met	missense variant	-	NC_000007.14:g.87509400G>T	NCI-TCGA
rs779984514	p.Leu1122Val	missense variant	-	NC_000007.14:g.87509400G>C	ExAC,gnomAD
rs1253462004	p.Asp1124Tyr	missense variant	-	NC_000007.14:g.87509394C>A	gnomAD
rs758212180	p.Cys1125Gly	missense variant	-	NC_000007.14:g.87509391A>C	ExAC,gnomAD
rs199894992	p.Ile1127Val	missense variant	-	NC_000007.14:g.87509385T>C	gnomAD
rs763091787	p.Glu1129Lys	missense variant	-	NC_000007.14:g.87509379C>T	ExAC,TOPMed,gnomAD
rs765229328	p.Asn1130Ile	missense variant	-	NC_000007.14:g.87509375T>A	ExAC,gnomAD
rs765229328	p.Asn1130Ser	missense variant	-	NC_000007.14:g.87509375T>C	ExAC,gnomAD
rs1314060722	p.Tyr1133Cys	missense variant	-	NC_000007.14:g.87509366T>C	gnomAD
rs767536622	p.Gly1134Arg	missense variant	-	NC_000007.14:g.87509364C>T	ExAC,gnomAD
rs767536622	p.Gly1134Ter	stop gained	-	NC_000007.14:g.87509364C>A	ExAC,gnomAD
rs774493186	p.Asp1135Glu	missense variant	-	NC_000007.14:g.87509359G>T	ExAC,gnomAD
rs766599262	p.Asn1136Ser	missense variant	-	NC_000007.14:g.87509357T>C	ExAC,gnomAD
rs773597757	p.Arg1138Trp	missense variant	-	NC_000007.14:g.87509352G>A	ExAC,TOPMed,gnomAD
rs200196668	p.Arg1138Gln	missense variant	-	NC_000007.14:g.87509351C>T	1000Genomes,ExAC,gnomAD
NCI-TCGA novel	p.Arg1138Leu	missense variant	-	NC_000007.14:g.87509351C>A	NCI-TCGA
rs2229107	p.Ser1141Thr	missense variant	-	NC_000007.14:g.87509343A>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs768115578	p.Glu1144Lys	missense variant	-	NC_000007.14:g.87509334C>T	ExAC,TOPMed,gnomAD
rs779788253	p.Val1146Met	missense variant	-	NC_000007.14:g.87509328C>T	ExAC,TOPMed,gnomAD
rs779788253	p.Val1146Leu	missense variant	-	NC_000007.14:g.87509328C>A	ExAC,TOPMed,gnomAD
rs1482837611	p.Arg1147Lys	missense variant	-	NC_000007.14:g.87509324C>T	gnomAD
rs1272689553	p.Ala1148Thr	missense variant	-	NC_000007.14:g.87509322C>T	gnomAD
rs201520086	p.Ala1152Ser	missense variant	-	NC_000007.14:g.87509310C>A	ExAC,gnomAD
rs201520086	p.Ala1152Thr	missense variant	-	NC_000007.14:g.87509310C>T	ExAC,gnomAD
rs1313948400	p.His1155Arg	missense variant	-	NC_000007.14:g.87509300T>C	TOPMed
rs778901580	p.Ala1156Gly	missense variant	-	NC_000007.14:g.87509297G>C	ExAC,gnomAD
rs745613481	p.Ala1156Pro	missense variant	-	NC_000007.14:g.87509298C>G	ExAC,gnomAD
rs200703943	p.Ile1158Met	missense variant	-	NC_000007.14:g.87509290G>C	ExAC,TOPMed,gnomAD
rs781320202	p.Glu1159Lys	missense variant	-	NC_000007.14:g.87509289C>T	ExAC,TOPMed,gnomAD
rs1410153460	p.Glu1159Asp	missense variant	-	NC_000007.14:g.87509287C>A	TOPMed,gnomAD
rs751662492	p.Pro1162Thr	missense variant	-	NC_000007.14:g.87509280G>T	ExAC,gnomAD
rs766547835	p.Asn1163Lys	missense variant	-	NC_000007.14:g.87509275A>T	ExAC,TOPMed,gnomAD
COSM1132923	p.Asn1163Asp	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87509277T>C	NCI-TCGA Cosmic
rs59241388	p.Lys1168Glu	missense variant	-	NC_000007.14:g.87506031T>C	1000Genomes,ExAC,TOPMed,gnomAD
rs780152885	p.Val1169Ile	missense variant	-	NC_000007.14:g.87506028C>T	ExAC,gnomAD
rs1473237773	p.Gly1173Arg	missense variant	-	NC_000007.14:g.87506016C>T	gnomAD
NCI-TCGA novel	p.Thr1174Ile	missense variant	-	NC_000007.14:g.87506012G>A	NCI-TCGA
COSM747743	p.Gln1175Ter	stop gained	Variant assessed as Somatic; HIGH impact.	NC_000007.14:g.87506010G>A	NCI-TCGA Cosmic
rs1466258029	p.Ser1177Cys	missense variant	-	NC_000007.14:g.87506003G>C	gnomAD
NCI-TCGA novel	p.Ser1177Phe	missense variant	-	NC_000007.14:g.87506003G>A	NCI-TCGA
rs1415144759	p.Gly1179Cys	missense variant	-	NC_000007.14:g.87505998C>A	TOPMed
rs1295088187	p.Gly1179GlyArgArgAspAspCysSerThrTerGluGluLeuCysTerLeuCysPheUnk	stop gained	-	NC_000007.14:g.87505996_87505997insAAAACAAAGTCAGCACAGCTCTTCTTAAGTACTGCAATCATCTCTTCTT	gnomAD
rs199676098	p.Arg1183Cys	missense variant	-	NC_000007.14:g.87505986G>A	ExAC,TOPMed,gnomAD
rs754264039	p.Arg1183His	missense variant	-	NC_000007.14:g.87505985C>T	ExAC,gnomAD
rs199676098	p.Arg1183Ser	missense variant	-	NC_000007.14:g.87505986G>T	ExAC,TOPMed,gnomAD
rs1281843123	p.Ile1184Val	missense variant	-	NC_000007.14:g.87505983T>C	TOPMed,gnomAD
rs764463583	p.Ala1185Asp	missense variant	-	NC_000007.14:g.87505979G>T	ExAC,gnomAD
COSM3641903	p.Ala1185Val	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87505979G>A	NCI-TCGA Cosmic
COSM6110891	p.Ile1186Thr	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87505976A>G	NCI-TCGA Cosmic
rs1400860335	p.Ile1186Val	missense variant	-	NC_000007.14:g.87505977T>C	TOPMed
rs139820108	p.Arg1188Gly	missense variant	-	NC_000007.14:g.87505971G>C	ESP,TOPMed
rs139820108	p.Arg1188Cys	missense variant	-	NC_000007.14:g.87505971G>A	ESP,TOPMed
rs201530445	p.Arg1188His	missense variant	-	NC_000007.14:g.87505970C>T	ExAC,TOPMed,gnomAD
rs1378191421	p.Ala1189Val	missense variant	-	NC_000007.14:g.87505967G>A	-
rs759250541	p.Gln1193Arg	missense variant	-	NC_000007.14:g.87505955T>C	ExAC,gnomAD
rs1285942204	p.Pro1194Thr	missense variant	-	NC_000007.14:g.87505953G>T	TOPMed
rs769925505	p.His1195Tyr	missense variant	-	NC_000007.14:g.87505950G>A	TOPMed
rs1366730591	p.Ile1196Val	missense variant	-	NC_000007.14:g.87505947T>C	gnomAD
NCI-TCGA novel	p.Leu1198Val	missense variant	-	NC_000007.14:g.87505941G>C	NCI-TCGA
COSM4834688	p.Asp1200His	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87505935C>G	NCI-TCGA Cosmic
rs770620028	p.Thr1203Arg	missense variant	-	NC_000007.14:g.87505925G>C	ExAC,TOPMed,gnomAD
rs770620028	p.Thr1203Met	missense variant	-	NC_000007.14:g.87505925G>A	ExAC,TOPMed,gnomAD
rs202030954	p.Ala1205Thr	missense variant	-	NC_000007.14:g.87505920C>T	gnomAD
rs769592199	p.Glu1209Lys	missense variant	-	NC_000007.14:g.87505908C>T	ExAC,TOPMed,gnomAD
rs769592199	p.Glu1209Gln	missense variant	-	NC_000007.14:g.87505908C>G	ExAC,TOPMed,gnomAD
COSM1452576	p.Ser1210Arg	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87505905T>G	NCI-TCGA Cosmic
rs1390471469	p.Ser1210Gly	missense variant	-	NC_000007.14:g.87505905T>C	TOPMed,gnomAD
rs1390471469	p.Ser1210Cys	missense variant	-	NC_000007.14:g.87505905T>A	TOPMed,gnomAD
rs201111035	p.Glu1211Ala	missense variant	-	NC_000007.14:g.87505901T>G	ExAC,gnomAD
rs1451623254	p.Lys1212Asn	missense variant	-	NC_000007.14:g.87505897C>G	gnomAD
rs1029583513	p.Lys1212Thr	missense variant	-	NC_000007.14:g.87505898T>G	TOPMed
rs1451623254	p.Lys1212Asn	missense variant	-	NC_000007.14:g.87505897C>A	gnomAD
NCI-TCGA novel	p.Val1213Ile	missense variant	-	NC_000007.14:g.87504449C>T	NCI-TCGA
COSM259270	p.Gln1215Arg	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87504442T>C	NCI-TCGA Cosmic
rs140995435	p.Glu1216Lys	missense variant	-	NC_000007.14:g.87504440C>T	gnomAD
COSM4844899	p.Ala1221Gly	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87504424G>C	NCI-TCGA Cosmic
rs768613690	p.Ala1221Pro	missense variant	-	NC_000007.14:g.87504425C>G	ExAC,gnomAD
rs1188387982	p.Arg1222Gly	missense variant	-	NC_000007.14:g.87504422T>C	gnomAD
rs1344972013	p.Arg1222Thr	missense variant	-	NC_000007.14:g.87504421C>G	gnomAD
NCI-TCGA novel	p.Glu1223Lys	missense variant	-	NC_000007.14:g.87504419C>T	NCI-TCGA
rs41309231	p.Glu1223Asp	missense variant	-	NC_000007.14:g.87504417T>A	TOPMed
rs779103120	p.Arg1225His	missense variant	-	NC_000007.14:g.87504412C>T	ExAC,gnomAD
rs1281746264	p.Arg1225Cys	missense variant	-	NC_000007.14:g.87504413G>A	TOPMed,gnomAD
rs1338160384	p.Thr1226Ala	missense variant	-	NC_000007.14:g.87504410T>C	TOPMed
rs1408243208	p.Ile1228Asn	missense variant	-	NC_000007.14:g.87504403A>T	gnomAD
rs757394498	p.Ile1230Val	missense variant	-	NC_000007.14:g.87504398T>C	ExAC,gnomAD
rs201578293	p.Arg1233Leu	missense variant	-	NC_000007.14:g.87504388C>A	ExAC,TOPMed,gnomAD
rs563375387	p.Arg1233Cys	missense variant	-	NC_000007.14:g.87504389G>A	1000Genomes,ExAC,TOPMed,gnomAD
rs201578293	p.Arg1233His	missense variant	-	NC_000007.14:g.87504388C>T	ExAC,TOPMed,gnomAD
rs200637194	p.Thr1236Ile	missense variant	-	NC_000007.14:g.87504379G>A	gnomAD
rs139750664	p.Ile1237Val	missense variant	-	NC_000007.14:g.87504377T>C	ESP,ExAC,gnomAD
rs755563103	p.Gln1238His	missense variant	-	NC_000007.14:g.87504372C>A	ExAC,TOPMed,gnomAD
rs201089646	p.Ala1240Ser	missense variant	-	NC_000007.14:g.87504368C>A	1000Genomes,ExAC,gnomAD
rs762504646	p.Asp1241Glu	missense variant	-	NC_000007.14:g.87504363G>C	ExAC,gnomAD
rs142093374	p.Asp1241Asn	missense variant	-	NC_000007.14:g.87504365C>T	ESP
rs1210266411	p.Leu1242Phe	missense variant	-	NC_000007.14:g.87504360T>G	gnomAD
rs1441356731	p.Ile1243Arg	missense variant	-	NC_000007.14:g.87504358A>C	gnomAD
rs772971590	p.Val1244Ala	missense variant	-	NC_000007.14:g.87504355A>G	ExAC,TOPMed,gnomAD
rs1230774968	p.Asn1248Lys	missense variant	-	NC_000007.14:g.87504342A>T	TOPMed,gnomAD
rs1470598507	p.Gly1249Ser	missense variant	-	NC_000007.14:g.87504341C>T	TOPMed
rs1373455786	p.Arg1250Ile	missense variant	-	NC_000007.14:g.87504337C>A	gnomAD
rs28364274	p.Val1251Ile	missense variant	-	NC_000007.14:g.87504335C>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1444127505	p.Lys1252Glu	missense variant	-	NC_000007.14:g.87504332T>C	gnomAD
rs768562415	p.Lys1252Arg	missense variant	-	NC_000007.14:g.87504331T>C	ExAC,TOPMed,gnomAD
rs1303671591	p.Glu1253Gln	missense variant	-	NC_000007.14:g.87504329C>G	gnomAD
rs1404008939	p.His1254Gln	missense variant	-	NC_000007.14:g.87504324A>C	TOPMed,gnomAD
rs1447340915	p.His1254Asn	missense variant	-	NC_000007.14:g.87504326G>T	gnomAD
rs1013586488	p.Gly1255Asp	missense variant	-	NC_000007.14:g.87504322C>T	TOPMed
COSM6110892	p.Gly1255Val	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87504322C>A	NCI-TCGA Cosmic
rs35721439	p.Thr1256Met	missense variant	-	NC_000007.14:g.87504319G>A	ExAC,TOPMed,gnomAD
rs35721439	p.Thr1256Lys	missense variant	-	NC_000007.14:g.87504319G>T	ExAC,TOPMed,gnomAD
rs771100707	p.His1257Tyr	missense variant	-	NC_000007.14:g.87504317G>A	ExAC,gnomAD
NCI-TCGA novel	p.His1257AlaPheSerTerUnkUnk	frameshift	-	NC_000007.14:g.87504314_87504318GATGC>-	NCI-TCGA
rs1044890354	p.His1257Arg	missense variant	-	NC_000007.14:g.87504316T>C	gnomAD
rs1044890354	p.His1257Pro	missense variant	-	NC_000007.14:g.87504316T>G	gnomAD
NCI-TCGA novel	p.Gln1263His	missense variant	-	NC_000007.14:g.87504297C>A	NCI-TCGA
rs1038514609	p.Gly1265Ser	missense variant	-	NC_000007.14:g.87504293C>T	TOPMed
NCI-TCGA novel	p.Ile1266Phe	missense variant	-	NC_000007.14:g.87504290T>A	NCI-TCGA
NCI-TCGA novel	p.Ile1266Leu	missense variant	-	NC_000007.14:g.87504290T>G	NCI-TCGA
rs1283093586	p.Ile1266Val	missense variant	-	NC_000007.14:g.87504290T>C	TOPMed
rs1415447553	p.Tyr1267Cys	missense variant	-	NC_000007.14:g.87504286T>C	gnomAD
rs1321813708	p.Ala1275Ser	missense variant	-	NC_000007.14:g.87504263C>A	TOPMed
COSM6178509	p.Gly1276Ala	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87504259C>G	NCI-TCGA Cosmic
NCI-TCGA novel	p.Thr1277Lys	missense variant	-	NC_000007.14:g.87504256G>T	NCI-TCGA
rs777987186	p.Thr1277Ala	missense variant	-	NC_000007.14:g.87504257T>C	ExAC,gnomAD
COSM3641901	p.Lys1278Glu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000007.14:g.87504254T>C	NCI-TCGA Cosmic
rs200263370	p.Arg1279His	missense variant	-	NC_000007.14:g.87504250C>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Arg1279Ser	missense variant	-	NC_000007.14:g.87504251G>T	NCI-TCGA
rs137996914	p.Arg1279Cys	missense variant	-	NC_000007.14:g.87504251G>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs200263370	p.Arg1279Leu	missense variant	-	NC_000007.14:g.87504250C>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1214032998	p.Gln1280His	missense variant	-	NC_000007.14:g.87504246C>A	gnomAD
rs202194143	p.Gln1280Pro	missense variant	-	NC_000007.14:g.87504247T>G	1000Genomes,ExAC,gnomAD

Disease or phenotype associated information

Disease ID	Disease Name	Disease Type	Source
C0000768	Congenital Abnormality	group	BEFREE
C0001175	Acquired Immunodeficiency Syndrome	group	BEFREE
C0001418	Adenocarcinoma	group	BEFREE;LHGDN
C0001430	Adenoma	group	BEFREE
C0001676	Adult Antisocial Behavior	phenotype	BEFREE
C0001824	Agranulocytosis	disease	BEFREE
C0002395	Alzheimer's Disease	disease	BEFREE;LHGDN
C0002726	Amyloidosis	disease	BEFREE
C0002871	Anemia	disease	BEFREE
C0002986	Fabry Disease	disease	BEFREE
C0003125	Anorexia Nervosa	disease	BEFREE
C0003467	Anxiety	disease	BEFREE
C0003469	Anxiety Disorders	group	BEFREE
C0003865	Arthritis, Adjuvant-Induced	disease	CTD_human
C0003872	Arthritis, Psoriatic	disease	BEFREE
C0003873	Rheumatoid Arthritis	disease	BEFREE;CTD_human
C0004093	Asthenia	phenotype	BEFREE
C0004364	Autoimmune Diseases	group	BEFREE
C0004623	Bacterial Infections	group	BEFREE
C0004698	Balkan Nephropathy	disease	LHGDN
C0004930	Behavior Disorders	group	CTD_human
C0004936	Mental disorders	group	CTD_human
C0005586	Bipolar Disorder	disease	BEFREE;PSYGENET
C0005684	Malignant neoplasm of urinary bladder	disease	BEFREE
C0005695	Bladder Neoplasm	group	BEFREE
C0005699	Blast Phase	disease	BEFREE
C0006111	Brain Diseases	group	BEFREE
C0006118	Brain Neoplasms	group	BEFREE
C0006142	Malignant neoplasm of breast	disease	BEFREE;CTD_human
C0006413	Burkitt Lymphoma	disease	BEFREE
C0006826	Malignant Neoplasms	group	BEFREE;CTD_human
C0006868	Cannabis Abuse	disease	CTD_human
C0006870	Cannabis Dependence	disease	BEFREE;CTD_human
C0007095	Carcinoid Tumor	group	BEFREE
C0007097	Carcinoma	group	CTD_human
C0007102	Malignant tumor of colon	disease	BEFREE
C0007103	Malignant neoplasm of endometrium	disease	BEFREE
C0007113	Rectal Carcinoma	disease	BEFREE
C0007114	Malignant neoplasm of skin	disease	BEFREE
C0007131	Non-Small Cell Lung Carcinoma	disease	BEFREE;CTD_human
C0007134	Renal Cell Carcinoma	disease	BEFREE;LHGDN
C0007137	Squamous cell carcinoma	disease	BEFREE
C0007138	Carcinoma, Transitional Cell	disease	BEFREE
C0007570	Celiac Disease	disease	BEFREE
C0007682	CNS disorder	group	BEFREE
C0007847	Malignant tumor of cervix	disease	BEFREE
C0008312	Primary biliary cirrhosis	disease	BEFREE
C0008370	Cholestasis	disease	BEFREE
C0008479	Chondrosarcoma	disease	BEFREE
C0008487	Chordoma	disease	BEFREE
C0008626	Congenital chromosomal disease	group	BEFREE
C0009207	Cockayne Syndrome	disease	BEFREE
C0009319	Colitis	disease	BEFREE
C0009324	Ulcerative Colitis	disease	BEFREE;LHGDN
C0009375	Colonic Neoplasms	group	BEFREE;LHGDN
C0009402	Colorectal Carcinoma	disease	BEFREE;CTD_human
C0009404	Colorectal Neoplasms	group	BEFREE;CTD_human;LHGDN
C0009782	Connective Tissue Diseases	group	BEFREE
C0010054	Coronary Arteriosclerosis	disease	BEFREE
C0010068	Coronary heart disease	disease	BEFREE
C0010346	Crohn Disease	disease	BEFREE;LHGDN
C0010674	Cystic Fibrosis	disease	BEFREE;LHGDN
C0010709	Cyst	phenotype	BEFREE
C0011206	Delirium	disease	BEFREE
C0011570	Mental Depression	disease	BEFREE;PSYGENET
C0011581	Depressive disorder	disease	BEFREE;PSYGENET
C0011854	Diabetes Mellitus, Insulin-Dependent	disease	BEFREE
C0011860	Diabetes Mellitus, Non-Insulin-Dependent	disease	BEFREE
C0011991	Diarrhea	phenotype	BEFREE
C0012833	Dizziness	phenotype	BEFREE
C0013080	Down Syndrome	disease	LHGDN
C0013221	Drug toxicity	group	CTD_human;CTD_mouse
C0014038	Encephalitis	disease	BEFREE;RGD
C0014170	Endometrial Neoplasms	group	LHGDN
C0014474	Ependymoma	disease	BEFREE
C0014544	Epilepsy	disease	BEFREE;CTD_human;LHGDN
C0014553	Absence Epilepsy	disease	BEFREE
C0014556	Epilepsy, Temporal Lobe	disease	BEFREE;LHGDN;RGD
C0014742	Erythema Multiforme	disease	BEFREE
C0014836	Escherichia coli Infections	group	CTD_human
C0014859	Esophageal Neoplasms	group	BEFREE;CTD_human
C0015371	Extrapyramidal Disorders	group	BEFREE
C0015672	Fatigue	phenotype	BEFREE
C0016057	Fibrosarcoma	disease	BEFREE
C0017152	Gastritis	disease	BEFREE
C0017178	Gastrointestinal Diseases	group	BEFREE
C0017636	Glioblastoma	disease	BEFREE;LHGDN
C0017638	Glioma	disease	BEFREE;LHGDN
C0017658	Glomerulonephritis	disease	BEFREE
C0018203	Chronic granulomatous disease	group	BEFREE
C0018524	Hallucinations	disease	BEFREE
C0018614	Hashish Abuse	disease	CTD_human
C0018798	Congenital Heart Defects	group	BEFREE;CTD_human
C0018799	Heart Diseases	group	CTD_mouse
C0018801	Heart failure	disease	BEFREE
C0018802	Congestive heart failure	disease	BEFREE
C0018816	Heart Septal Defects	group	BEFREE
C0018939	Hematological Disease	group	BEFREE
C0019158	Hepatitis	disease	BEFREE
C0019159	Hepatitis A	disease	BEFREE
C0019163	Hepatitis B	disease	BEFREE
C0019193	Hepatitis, Toxic	disease	CTD_human;CTD_mouse
C0019337	Heroin Dependence	disease	BEFREE
C0019348	Herpes Simplex Infections	group	BEFREE
C0019623	Malignant histiocytosis	disease	BEFREE
C0019693	HIV Infections	group	BEFREE;RGD
C0019829	Hodgkin Disease	disease	BEFREE
C0020097	HTLV-I Infections	group	BEFREE
C0020179	Huntington Disease	disease	BEFREE
C0020433	Hyperbilirubinemia	disease	BEFREE
C0020443	Hypercholesterolemia	disease	BEFREE
C0020445	Hypercholesterolemia, Familial	disease	BEFREE
C0020473	Hyperlipidemia	disease	CTD_mouse
C0020529	Hypersomnia with Periodic Respiration	disease	RGD
C0020538	Hypertensive disease	group	BEFREE
C0020550	Hyperthyroidism	disease	LHGDN
C0020625	Hyponatremia	phenotype	BEFREE
C0020651	Hypotension, Orthostatic	phenotype	CTD_human
C0021294	Infant, Premature	phenotype	BEFREE
C0021368	Inflammation	phenotype	LHGDN
C0021390	Inflammatory Bowel Diseases	group	BEFREE;LHGDN
C0021400	Influenza	disease	BEFREE
C0022333	Jacksonian Seizure	disease	CTD_mouse
C0022336	Creutzfeldt-Jakob disease	disease	BEFREE;LHGDN
C0022610	Kernicterus	disease	BEFREE
C0022658	Kidney Diseases	group	BEFREE;CTD_mouse
C0022660	Kidney Failure, Acute	disease	BEFREE
C0022661	Kidney Failure, Chronic	disease	BEFREE;RGD
C0022665	Kidney Neoplasm	disease	BEFREE;CTD_human
C0023269	leiomyosarcoma	disease	BEFREE;LHGDN
C0023418	leukemia	disease	BEFREE;LHGDN
C0023434	Chronic Lymphocytic Leukemia	disease	BEFREE
C0023440	Acute Erythroblastic Leukemia	disease	BEFREE
C0023448	Lymphoid leukemia	disease	BEFREE
C0023449	Acute lymphocytic leukemia	disease	BEFREE
C0023452	Childhood Acute Lymphoblastic Leukemia	disease	BEFREE;CTD_human
C0023453	Leukemia, Lymphocytic, Acute, L2	disease	CTD_human
C0023462	Acute Megakaryocytic Leukemias	disease	BEFREE
C0023464	Acute biphenotypic leukemia	disease	BEFREE
C0023467	Leukemia, Myelocytic, Acute	disease	BEFREE;LHGDN
C0023470	Myeloid Leukemia	disease	BEFREE;LHGDN
C0023473	Myeloid Leukemia, Chronic	disease	BEFREE;LHGDN
C0023474	Leukemia, Myeloid, Chronic-Phase	disease	BEFREE
C0023486	Prolymphocytic Leukemia	disease	BEFREE
C0023487	Acute Promyelocytic Leukemia	disease	BEFREE;LHGDN
C0023492	Leukemia, T-Cell	disease	BEFREE
C0023493	Adult T-Cell Lymphoma/Leukemia	disease	BEFREE
C0023530	Leukopenia	disease	BEFREE
C0023798	Lipoma	disease	BEFREE
C0023827	liposarcoma	disease	BEFREE
C0023890	Liver Cirrhosis	disease	BEFREE
C0023893	Liver Cirrhosis, Experimental	disease	CTD_human;CTD_mouse
C0023903	Liver neoplasms	group	BEFREE;LHGDN
C0024121	Lung Neoplasms	group	BEFREE;LHGDN
C0024141	Lupus Erythematosus, Systemic	disease	BEFREE
C0024205	Lymphadenitis	disease	BEFREE
C0024299	Lymphoma	group	BEFREE;LHGDN
C0024301	Lymphoma, Follicular	disease	BEFREE
C0024305	Lymphoma, Non-Hodgkin	disease	BEFREE;LHGDN
C0024314	Lymphoproliferative Disorders	group	BEFREE
C0024530	Malaria	disease	BEFREE
C0024535	Malaria, Falciparum	disease	BEFREE
C0024620	Primary Malignant Liver Neoplasm	disease	BEFREE
C0024623	Malignant neoplasm of stomach	disease	BEFREE
C0024809	Marijuana Abuse	disease	CTD_human
C0025149	Medulloblastoma	disease	BEFREE
C0025202	melanoma	disease	BEFREE;LHGDN
C0025286	Meningioma	disease	BEFREE
C0025500	Mesothelioma	disease	BEFREE
C0026499	Monosomy	group	BEFREE
C0026764	Multiple Myeloma	disease	BEFREE;LHGDN
C0026896	Myasthenia Gravis	disease	BEFREE
C0026985	Myelodysplasia	disease	BEFREE
C0027022	Myeloproliferative disease	group	BEFREE
C0027051	Myocardial Infarction	disease	BEFREE
C0027497	Nausea	phenotype	CTD_human
C0027498	Nausea and vomiting	phenotype	BEFREE
C0027609	Neonatal Abstinence Syndrome	disease	BEFREE;PSYGENET
C0027627	Neoplasm Metastasis	phenotype	BEFREE;CTD_human
C0027651	Neoplasms	group	BEFREE;CTD_human
C0027708	Nephroblastoma	disease	BEFREE
C0027726	Nephrotic Syndrome	group	BEFREE
C0027765	nervous system disorder	group	BEFREE;CTD_human
C0027809	Neurilemmoma	disease	BEFREE
C0027819	Neuroblastoma	group	BEFREE;CTD_human;LHGDN
C0027947	Neutropenia	disease	BEFREE;CTD_human
C0028754	Obesity	disease	BEFREE
C0029445	Bone necrosis	phenotype	LHGDN
C0029456	Osteoporosis	disease	BEFREE
C0029463	Osteosarcoma	disease	BEFREE
C0029925	Ovarian Carcinoma	disease	BEFREE
C0030193	Pain	phenotype	BEFREE;CTD_mouse
C0030201	Pain, Postoperative	phenotype	BEFREE;CTD_human
C0030499	Parasitic Diseases	group	BEFREE
C0030567	Parkinson Disease	disease	BEFREE;CTD_human;LHGDN
C0030569	Secondary Parkinson Disease	disease	CTD_human
C0030807	Pemphigus	disease	BEFREE
C0030920	Peptic Ulcer	disease	BEFREE
C0031069	Familial Mediterranean Fever	disease	BEFREE;LHGDN
C0031117	Peripheral Neuropathy	group	BEFREE;CTD_human
C0032019	Pituitary Neoplasms	group	LHGDN
C0032343	Poisoning	group	CTD_human
C0032580	Adenomatous Polyposis Coli	disease	BEFREE
C0032927	Precancerous Conditions	group	BEFREE
C0032969	Pregnancy in Diabetics	phenotype	BEFREE
C0033578	Prostatic Neoplasms	group	BEFREE;LHGDN
C0033860	Psoriasis	disease	BEFREE
C0033975	Psychotic Disorders	group	BEFREE;PSYGENET
C0034341	Pyruvate Carboxylase Deficiency Disease	disease	BEFREE
C0035126	Reperfusion Injury	disease	CTD_mouse
C0035335	Retinoblastoma	disease	BEFREE
C0035369	Retroviridae Infections	group	BEFREE
C0035412	Rhabdomyosarcoma	disease	BEFREE
C0035435	Rheumatism	disease	BEFREE
C0036220	Kaposi Sarcoma	disease	BEFREE
C0036337	Schizoaffective Disorder	disease	BEFREE
C0036341	Schizophrenia	disease	BEFREE;GWASCAT;PSYGENET
C0036572	Seizures	phenotype	BEFREE;CTD_mouse
C0037315	Sleep Apnea Syndromes	group	RGD
C0037317	Sleep disturbances	group	BEFREE
C0037579	Soft Tissue Neoplasms	group	BEFREE
C0037999	Splenic Neoplasms	group	BEFREE
C0038220	Status Epilepticus	disease	CTD_mouse
C0038356	Stomach Neoplasms	group	LHGDN
C0038454	Cerebrovascular accident	group	BEFREE
C0039101	synovial sarcoma	disease	BEFREE
C0040034	Thrombocytopenia	phenotype	BEFREE
C0040128	Thyroid Diseases	group	BEFREE
C0040715	Chromosomal translocation	group	CTD_human
C0041296	Tuberculosis	disease	BEFREE
C0041327	Tuberculosis, Pulmonary	disease	BEFREE
C0041341	Tuberous Sclerosis	disease	LHGDN
C0041696	Unipolar Depression	disease	BEFREE;PSYGENET
C0041755	Adverse reaction to drug	group	CTD_human;CTD_mouse
C0042571	Vertigo	phenotype	BEFREE
C0042721	Viral hepatitis	group	BEFREE
C0042749	Viremia	disease	BEFREE
C0042961	Intestinal Volvulus	disease	BEFREE
C0042963	Vomiting	phenotype	BEFREE;CTD_human
C0079588	Ichthyosis, X-Linked	disease	BEFREE
C0079731	B-Cell Lymphomas	group	BEFREE
C0079744	Diffuse Large B-Cell Lymphoma	disease	BEFREE;CTD_human
C0079745	Lymphoma, Large-Cell, Follicular	disease	BEFREE
C0079746	Immunoblastic Large-Cell Lymphoma	disease	BEFREE
C0079772	T-Cell Lymphoma	disease	BEFREE;LHGDN
C0079773	Lymphoma, T-Cell, Cutaneous	disease	BEFREE
C0079774	Peripheral T-Cell Lymphoma	disease	BEFREE
C0085090	Lymphoma, AIDS-Related	disease	BEFREE
C0085220	Cerebral Amyloid Angiopathy	disease	BEFREE;LHGDN
C0085281	Addictive Behavior	phenotype	BEFREE
C0085584	Encephalopathies	group	BEFREE
C0085602	Polydipsia	phenotype	BEFREE
C0085669	Acute leukemia	disease	BEFREE
C0085695	Chronic gastritis	disease	BEFREE
C0086132	Depressive Symptoms	phenotype	BEFREE
C0086237	Epilepsy, Cryptogenic	disease	CTD_human
C0086543	Cataract	disease	BEFREE
C0086692	Benign Neoplasm	group	CTD_human
C0087169	Withdrawal Symptoms	phenotype	BEFREE
C0149504	Encephalopathy, Toxic	disease	CTD_human
C0149521	Pancreatitis, Chronic	disease	BEFREE
C0149678	Epstein-Barr Virus Infections	group	BEFREE
C0149782	Squamous cell carcinoma of lung	disease	BEFREE
C0149925	Small cell carcinoma of lung	disease	BEFREE
C0149958	Complex partial seizures	disease	BEFREE;CTD_mouse
C0151313	Sensory neuropathy	disease	BEFREE
C0151546	Oral Cavity Carcinoma	disease	BEFREE
C0151559	Central nervous system depression (disorder)	disease	BEFREE
C0151650	Renal fibrosis	disease	BEFREE
C0152013	Adenocarcinoma of lung (disorder)	disease	BEFREE
C0152018	Esophageal carcinoma	disease	BEFREE
C0153381	Malignant neoplasm of mouth	disease	BEFREE
C0153452	Malignant neoplasm of gallbladder	disease	BEFREE
C0153467	Malignant tumor of peritoneum	disease	BEFREE
C0153567	Uterine Cancer	disease	BEFREE
C0153633	Malignant neoplasm of brain	disease	BEFREE
C0153676	Secondary malignant neoplasm of lung	disease	BEFREE
C0153690	Secondary malignant neoplasm of bone	disease	BEFREE
C0154659	Toxic Encephalitis	disease	CTD_human
C0155626	Acute myocardial infarction	disease	BEFREE
C0162532	Variegate Porphyria	disease	BEFREE
C0162830	Dermatitis, Phototoxic	disease	BEFREE
C0178874	Tumor Progression	phenotype	BEFREE
C0205696	Anaplastic carcinoma	disease	CTD_human
C0205697	Carcinoma, Spindle-Cell	disease	CTD_human
C0205698	Undifferentiated carcinoma	phenotype	CTD_human
C0205699	Carcinomatosis	phenotype	CTD_human
C0205825	Liposarcoma, Pleomorphic	disease	BEFREE
C0206180	Ki-1+ Anaplastic Large Cell Lymphoma	disease	BEFREE
C0206525	Tuberculosis, Drug-Resistant	disease	BEFREE
C0206624	Hepatoblastoma	disease	BEFREE
C0206629	Pulmonary Blastoma	disease	BEFREE
C0206663	Neuroectodermal Tumor, Primitive	disease	BEFREE
C0206681	Adenocarcinoma, Clear Cell	disease	BEFREE
C0206686	Adrenocortical carcinoma	disease	BEFREE;CTD_human
C0206692	Carcinoma, Lobular	disease	BEFREE
C0206694	Mucoepidermoid Carcinoma	disease	BEFREE
C0206698	Cholangiocarcinoma	disease	BEFREE
C0206702	Klatskin Tumor	disease	BEFREE
C0206730	Neurothekeoma	disease	BEFREE
C0220613	Adult Soft Tissue Sarcoma	disease	BEFREE
C0220615	Adult Acute Myeloblastic Leukemia	disease	BEFREE
C0220621	Childhood Acute Myeloid Leukemia	disease	BEFREE
C0220633	Uveal melanoma	disease	BEFREE
C0220641	Lip and Oral Cavity Carcinoma	disease	BEFREE
C0220656	Malignant ascites	disease	BEFREE
C0220668	Congenital contractural arachnodactyly	disease	BEFREE
C0220756	Niemann-Pick Disease, Type C	disease	BEFREE
C0220810	Congenital defects	group	BEFREE
C0234230	Pain, Burning	phenotype	CTD_mouse
C0234238	Ache	phenotype	CTD_mouse
C0234254	Radiating pain	phenotype	CTD_mouse
C0234533	Generalized seizures	disease	CTD_mouse
C0234535	Seizures, Clonic	disease	CTD_mouse
C0235032	Neurotoxicity Syndromes	group	CTD_human
C0235782	Gallbladder Carcinoma	disease	BEFREE
C0235874	Disease Exacerbation	phenotype	CTD_human
C0235974	Pancreatic carcinoma	disease	BEFREE
C0236018	Aura	phenotype	CTD_human
C0236735	Cannabis-Related Disorder	group	CTD_human
C0237123	Alcohol or Other Drugs use	disease	BEFREE
C0237967	pediatric AIDS	disease	BEFREE
C0238198	Gastrointestinal Stromal Tumors	group	LHGDN
C0238461	Anaplastic thyroid carcinoma	disease	BEFREE
C0239849	Harlequin Fetus	disease	BEFREE
C0242339	Dyslipidemias	group	BEFREE
C0242379	Malignant neoplasm of lung	disease	BEFREE
C0242510	Drug usage	phenotype	BEFREE
C0242596	Neoplasm, Residual	phenotype	LHGDN
C0242852	Proliferative vitreoretinopathy	disease	BEFREE
C0262587	Parathyroid Adenoma	disease	BEFREE
C0267924	Suppurative cholangitis	disease	BEFREE
C0268136	Xeroderma pigmentosum, group B	disease	BEFREE
C0268312	Progressive intrahepatic cholestasis (disorder)	disease	BEFREE
C0268615	5,10-Methylenetetrahydrofolate reductase deficiency	disease	BEFREE
C0270823	Petit mal status	disease	CTD_mouse
C0270824	Visual seizure	disease	CTD_mouse;RGD
C0270844	Tonic Seizures	phenotype	CTD_mouse
C0270846	Epileptic drop attack	disease	CTD_mouse
C0270853	Juvenile Myoclonic Epilepsy	disease	BEFREE
C0278488	Carcinoma breast stage IV	disease	BEFREE
C0278504	Non-small cell lung cancer stage I	disease	BEFREE
C0278678	Metastatic Renal Cell Cancer	disease	BEFREE
C0278694	Disseminated neuroblastoma	disease	BEFREE
C0278701	Gastric Adenocarcinoma	disease	BEFREE
C0278719	Extraocular retinoblastoma	disease	BEFREE
C0278802	Recurrent Endometrial Cancer	disease	BEFREE
C0278828	Stage IV Bladder Cancer AJCC v6	disease	BEFREE
C0278996	Malignant Head and Neck Neoplasm	disease	BEFREE
C0279000	Liver and Intrahepatic Biliary Tract Carcinoma	disease	BEFREE
C0279543	Philadelphia chromosome positive chronic myelogenous leukemia	disease	BEFREE
C0279607	Adult Hepatocellular Carcinoma	disease	RGD
C0279626	Squamous cell carcinoma of esophagus	disease	BEFREE
C0279650	Childhood Acute Megakaryoblastic Leukemia	disease	BEFREE
C0279672	Cervical Adenocarcinoma	disease	BEFREE
C0279702	Conventional (Clear Cell) Renal Cell Carcinoma	disease	BEFREE
C0280100	Solid Neoplasm	phenotype	BEFREE
C0280220	stage, ovarian epithelial cancer	disease	BEFREE
C0280449	secondary acute myeloid leukemia	disease	BEFREE
C0280725	Adult Cholangiocarcinoma	disease	BEFREE
C0302592	Cervix carcinoma	disease	BEFREE
C0311335	Grand Mal Status Epilepticus	disease	CTD_mouse
C0333463	Senile Plaques	phenotype	BEFREE
C0334359	Papillary serous cystadenocarcinoma	disease	BEFREE
C0334463	Malignant Fibrous Histiocytoma	disease	BEFREE
C0334579	Anaplastic astrocytoma	disease	BEFREE
C0334590	Anaplastic Oligodendroglioma	disease	BEFREE
C0338106	Adenocarcinoma of colon	disease	BEFREE
C0338113	Uterine Corpus Sarcoma	disease	BEFREE
C0338495	Sleep Apnea, Mixed Central and Obstructive	disease	RGD
C0338656	Impaired cognition	disease	BEFREE
C0338831	Manic	disease	BEFREE;PSYGENET
C0339543	Epiretinal Membrane	phenotype	BEFREE
C0345904	Malignant neoplasm of liver	disease	BEFREE
C0345905	Intrahepatic Cholangiocarcinoma	disease	BEFREE
C0345906	Sarcoma of liver	disease	BEFREE
C0345967	Malignant mesothelioma	disease	BEFREE
C0346153	Breast Cancer, Familial	disease	BEFREE
C0346402	Malignant neoplasm of adrenal cortex	disease	BEFREE
C0346629	Malignant neoplasm of large intestine	disease	BEFREE
C0346647	Malignant neoplasm of pancreas	disease	BEFREE
C0349204	Nonorganic psychosis	disease	BEFREE
C0376338	Diagnosis, Psychiatric	disease	CTD_human
C0376358	Malignant neoplasm of prostate	disease	BEFREE
C0376544	Hematopoietic Neoplasms	group	BEFREE;CTD_human
C0376545	Hematologic Neoplasms	group	BEFREE;CTD_human
C0376620	Pouchitis	disease	BEFREE
C0376670	Pancreatitis, Alcoholic	disease	BEFREE
C0392514	Hereditary hemochromatosis	disease	BEFREE
C0393734	Complex Partial Status Epilepticus	disease	CTD_mouse
C0403397	Steroid-resistant nephrotic syndrome	disease	BEFREE
C0410207	Tubular Aggregate Myopathy	disease	BEFREE
C0422850	Seizures, Somatosensory	phenotype	CTD_mouse
C0422852	Seizures, Auditory	phenotype	CTD_mouse
C0422853	Olfactory seizure	disease	CTD_mouse
C0422854	Gustatory seizure	phenotype	CTD_mouse
C0422855	Vertiginous seizure	disease	CTD_mouse
C0424295	Hyperactive behavior	phenotype	BEFREE
C0442874	Neuropathy	group	BEFREE
C0458257	Pain, Splitting	phenotype	CTD_mouse
C0458259	Pain, Crushing	phenotype	CTD_mouse
C0458960	Peripheral neuropathic pain	phenotype	BEFREE
C0476089	Endometrial Carcinoma	disease	BEFREE
C0494165	Secondary malignant neoplasm of liver	disease	BEFREE
C0494463	Alzheimer Disease, Late Onset	disease	BEFREE
C0494475	Tonic - clonic seizures	disease	CTD_mouse
C0496870	Benign neoplasm of liver	disease	BEFREE
C0497169	hiv-infection/aids	disease	BEFREE
C0520680	Sleep Apnea, Central	disease	BEFREE
C0520904	Postoperative Nausea	phenotype	BEFREE
C0520909	Postoperative Nausea and Vomiting	phenotype	BEFREE
C0521585	Gastrointestinal mucositis	disease	BEFREE
C0521857	Increased drug resistance	phenotype	BEFREE
C0522631	Acute myeloid leukemia, minimal differentiation	disease	BEFREE
C0524662	Opiate Addiction	disease	BEFREE
C0524851	Neurodegenerative Disorders	group	BEFREE
C0524909	Hepatitis B, Chronic	disease	BEFREE
C0546837	Malignant neoplasm of esophagus	disease	BEFREE;CTD_human
C0547030	Visual disturbance	phenotype	BEFREE
C0549410	Palmar-plantar erythrodysesthesia syndrome	disease	BEFREE
C0549473	Thyroid carcinoma	disease	BEFREE
C0553580	Ewings sarcoma	disease	BEFREE
C0555198	Malignant Glioma	disease	BEFREE
C0558356	Malignant melanoma of eye	disease	BEFREE
C0563625	Agnosia for Pain	disease	BEFREE
C0566602	Primary sclerosing cholangitis	disease	BEFREE
C0581391	Chronic depression	disease	BEFREE
C0585442	Osteosarcoma of bone	disease	BEFREE
C0595989	Carcinoma of larynx	disease	BEFREE
C0596263	Carcinogenesis	phenotype	BEFREE
C0598766	Leukemogenesis	disease	BEFREE
C0598894	Monocytic leukemia	disease	BEFREE
C0598935	Tumor Initiation	phenotype	BEFREE
C0600139	Prostate carcinoma	disease	BEFREE
C0600427	Cocaine Dependence	disease	BEFREE
C0677483	Carcinoma testes	disease	BEFREE
C0677886	Epithelial ovarian cancer	disease	BEFREE
C0677932	Progressive Neoplastic Disease	phenotype	BEFREE
C0677936	Refractory cancer	phenotype	BEFREE
C0678222	Breast Carcinoma	disease	BEFREE;CTD_human
C0684249	Carcinoma of lung	disease	BEFREE
C0685938	Malignant neoplasm of gastrointestinal tract	disease	BEFREE
C0686619	Secondary malignant neoplasm of lymph node	disease	BEFREE
C0699753	Cancer Relapse	disease	BEFREE
C0699790	Colon Carcinoma	disease	BEFREE
C0699791	Stomach Carcinoma	disease	BEFREE
C0699885	Carcinoma of bladder	disease	BEFREE
C0700095	Central neuroblastoma	disease	BEFREE
C0740457	Malignant neoplasm of kidney	disease	BEFREE;CTD_human
C0741923	cardiac event	phenotype	BEFREE
C0742472	Central nervous system lymphoma	group	BEFREE
C0745103	Hyperlipoproteinemia Type IIa	disease	BEFREE
C0746883	Febrile Neutropenia	disease	BEFREE
C0747845	early pregnancy	phenotype	BEFREE
C0748505	Sarcoma, metastatic	disease	BEFREE
C0750384	Coumarin Resistance	phenotype	BEFREE
C0750974	Brain Tumor, Primary	disease	BEFREE
C0750979	Primary malignant neoplasm of brain	disease	BEFREE
C0751039	Cockayne Syndrome, Type I	disease	BEFREE
C0751056	Non-epileptic convulsion	phenotype	CTD_mouse
C0751110	Single Seizure	disease	CTD_mouse
C0751111	Awakening Epilepsy	disease	CTD_human
C0751123	Atonic Absence Seizures	disease	CTD_mouse
C0751407	Pain, Migratory	phenotype	CTD_mouse
C0751408	Suffering, Physical	phenotype	CTD_mouse
C0751414	Parkinson Disease, Secondary Vascular	disease	CTD_human
C0751415	Atherosclerotic Parkinsonism	disease	CTD_human
C0751494	Convulsive Seizures	phenotype	CTD_mouse
C0751495	Seizures, Focal	phenotype	CTD_mouse
C0751496	Seizures, Sensory	phenotype	CTD_mouse
C0751522	Status Epilepticus, Subclinical	disease	CTD_mouse
C0751523	Non-Convulsive Status Epilepticus	disease	CTD_mouse
C0751524	Simple Partial Status Epilepticus	disease	CTD_mouse
C0751606	Adult Acute Lymphocytic Leukemia	disease	BEFREE
C0751688	Malignant Squamous Cell Neoplasm	disease	BEFREE
C0751690	Malignant Peripheral Nerve Sheath Tumor	disease	BEFREE
C0809983	Schizophrenia and related disorders	group	BEFREE
C0850666	Infection caused by Helicobacter pylori	disease	BEFREE
C0851578	Sleep Disorders	group	BEFREE
C0852711	Sickle Cell Dactylitis	disease	BEFREE
C0853879	Invasive carcinoma of breast	disease	BEFREE
C0855073	Undifferentiated (Embryonal) Sarcoma	disease	BEFREE
C0856053	Leukemia secondary	disease	BEFREE
C0858252	Breast adenocarcinoma	disease	BEFREE
C0860207	Drug-Induced Liver Disease	disease	BEFREE;CTD_human;CTD_mouse
C0868908	Pancolitis	disease	BEFREE
C0919267	ovarian neoplasm	disease	BEFREE;LHGDN
C0948008	Ischemic stroke	disease	BEFREE
C0948089	Acute Coronary Syndrome	disease	BEFREE
C0948216	Ovarian adenocarcinoma	disease	BEFREE
C0949541	Hurthle Cell Tumor	disease	BEFREE
C0971858	Arthritis, Collagen-Induced	disease	CTD_human
C0993582	Arthritis, Experimental	disease	CTD_human
C1096063	Drug Resistant Epilepsy	disease	BEFREE
C1135161	Stage 4S neuroblastoma	disease	BEFREE
C1140680	Malignant neoplasm of ovary	disease	BEFREE
C1167791	Skin toxicity	disease	BEFREE
C1168327	High-Grade Prostatic Intraepithelial Neoplasia	disease	BEFREE
C1168401	Squamous cell carcinoma of the head and neck	disease	BEFREE;CTD_human
C1257931	Mammary Neoplasms, Human	group	CTD_human
C1261473	Sarcoma	group	BEFREE;LHGDN
C1262760	Hepatitis, Drug-Induced	disease	CTD_human;CTD_mouse
C1269683	Major Depressive Disorder	disease	BEFREE;PSYGENET
C1279296	Chronic leukemia (category)	disease	BEFREE
C1279481	X-Linked Combined Immunodeficiency Diseases	disease	BEFREE
C1292769	Precursor B-cell lymphoblastic leukemia	disease	BEFREE
C1292777	Aggressive natural killer-cell leukemia	disease	BEFREE
C1292778	Chronic myeloproliferative disorder	disease	BEFREE
C1306459	Primary malignant neoplasm	group	BEFREE
C1306460	Primary malignant neoplasm of lung	disease	BEFREE
C1314691	Age at menarche	phenotype	GWASCAT
C1318544	M5b Acute differentiated monocytic leukemia	disease	BEFREE
C1319315	Adenocarcinoma of large intestine	disease	BEFREE
C1332051	AIDS-Related Non-Hodgkin Lymphoma	disease	BEFREE
C1332153	Acute Myeloid Leukemia Arising from Previous Myelodysplastic Syndrome	disease	BEFREE
C1332850	Cardiac Lymphoma	disease	BEFREE
C1332977	Childhood Leukemia	disease	BEFREE
C1332986	Childhood Osteosarcoma	disease	BEFREE
C1334170	Indolent Non-Hodgkin Lymphoma	disease	BEFREE
C1334708	Metaplastic breast carcinoma	disease	BEFREE
C1336527	Carcinoma of urinary bladder, superficial	disease	BEFREE
C1368683	Epithelioma	disease	BEFREE
C1378050	Oncocytic Neoplasm	disease	BEFREE
C1378511	Undifferentiated leukemia	disease	BEFREE
C1378703	Renal carcinoma	disease	BEFREE
C1402294	Primary Lesion	phenotype	BEFREE
C1458155	Mammary Neoplasms	group	BEFREE;CTD_human;LHGDN
C1510502	Oxyphilic Adenoma	disease	BEFREE
C1519670	Tumor Angiogenesis	phenotype	BEFREE
C1527249	Colorectal Cancer	disease	BEFREE;CTD_human;UNIPROT
C1527358	Phototoxicity	disease	BEFREE
C1527390	Neoplasms, Intracranial	group	BEFREE
C1533172	Infantile nystagmus syndrome	disease	BEFREE
C1535510	ADENOMAS AND ADENOCARCINOMAS	group	BEFREE
C1559154	Rash and Dermatitis Adverse Event Associated with Chemoradiation	disease	BEFREE
C1561643	Chronic Kidney Diseases	group	BEFREE
C1565489	Renal Insufficiency	disease	BEFREE
C1565951	Sphenoid Wing Meningioma	disease	BEFREE
C1621958	Glioblastoma Multiforme	disease	BEFREE
C1623038	Cirrhosis	disease	BEFREE
C1654637	androgen independent prostate cancer	disease	BEFREE
C1658953	tumor vasculature	phenotype	BEFREE
C1704272	Benign Prostatic Hyperplasia	disease	BEFREE
C1704321	Nephrotic Syndrome, Minimal Change	disease	BEFREE
C1704423	Milroy Disease	disease	BEFREE
C1706412	Lipidemias	phenotype	CTD_mouse
C1707444	Columnar Cell Change of the Breast	phenotype	BEFREE
C1720830	Painful Bladder Syndrome	disease	BEFREE
C1762616	Meningioma, benign, no ICD-O subtype	disease	BEFREE
C1834582	MYELOPROLIFERATIVE SYNDROME, TRANSIENT	disease	BEFREE
C1841972	Glucocorticoid Receptor Deficiency	disease	BEFREE
C1844376	Granulomatous Disease, Chronic, X-Linked	disease	BEFREE
C1848296	DOSAGE-SENSITIVE SEX REVERSAL	disease	BEFREE
C1861305	TARSAL-CARPAL COALITION SYNDROME	disease	BEFREE
C1861502	COLCHICINE RESISTANCE	phenotype	BEFREE;CLINVAR
C1863925	Nonmedullary thyroid carcinoma, with or without cell oxyphilia	disease	BEFREE
C1863999	Peroxisome Biogenesis Disorder, Complementation Group D	disease	BEFREE
C1879321	Acute Myeloid Leukemia (AML-M2)	disease	BEFREE
C1883486	Uterine Corpus Cancer	disease	BEFREE
C1956346	Coronary Artery Disease	disease	BEFREE
C1959584	Cardiac Carcinoma	disease	BEFREE
C1961099	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	disease	BEFREE
C1961102	Precursor Cell Lymphoblastic Leukemia Lymphoma	disease	BEFREE;CTD_human;LHGDN
C2215257	Acute postoperative pain	phenotype	BEFREE
C2239176	Liver carcinoma	disease	BEFREE;CTD_human;LHGDN
C2316810	Chronic kidney disease stage 5	disease	BEFREE;RGD
C2677101	Inflammatory Bowel Disease 13	disease	CTD_human;MGD
C2717836	Steroid Sulfatase Deficiency Disease	disease	BEFREE
C2931822	Nasopharyngeal carcinoma	disease	BEFREE
C2931852	Clear-cell metastatic renal cell carcinoma	disease	BEFREE
C2936349	Plaque, Amyloid	phenotype	BEFREE
C2936476	Chronic Liver Failure	disease	BEFREE
C2986665	Early-Stage Breast Carcinoma	disease	BEFREE
C3266102	Steroid resistant nephrotic syndrome of childhood	disease	BEFREE
C3266262	Multiple Chronic Conditions	disease	BEFREE
C3463824	MYELODYSPLASTIC SYNDROME	group	BEFREE;LHGDN
C3472614	Plasmablastic lymphoma	disease	BEFREE
C3495559	Juvenile arthritis	disease	BEFREE
C3495874	Nonepileptic Seizures	disease	CTD_mouse
C3496337	Idiopathic Nephrotic Syndrome	disease	BEFREE
C3536893	Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor	disease	BEFREE
C3539781	Progressive cGVHD	disease	BEFREE
C3539878	Triple Negative Breast Neoplasms	disease	BEFREE
C3549742	Breast cancer, lobular	disease	BEFREE
C3658290	Drug-Induced Acute Liver Injury	disease	CTD_human;CTD_mouse
C3714757	Juvenile rheumatoid arthritis	disease	BEFREE
C3714948	PACHYONYCHIA CONGENITA 3	disease	BEFREE
C3839741	Core binding factor acute myeloid leukemia	disease	BEFREE
C3839868	Cytogenetically normal acute myeloid leukemia	disease	BEFREE
C3874381	Childhood nephrotic syndrome	disease	BEFREE
C3887486	Interstitial lung fibrosis	phenotype	BEFREE
C3899731	Calcineurin Nephrotoxicity	disease	BEFREE
C4021813	Oral cleft	disease	BEFREE
C4046029	Mental Disorders, Severe	group	CTD_human
C4048158	Convulsions	phenotype	CTD_mouse
C4048305	Neuroepithelioma	disease	BEFREE
C4048328	cervical cancer	disease	BEFREE
C4054892	Grade II Chondrosarcoma	disease	BEFREE
C4086165	Childhood Neuroblastoma	disease	BEFREE
C4277682	Chemical and Drug Induced Liver Injury	disease	CTD_human;CTD_mouse
C4279912	Chemically-Induced Liver Toxicity	disease	CTD_human;CTD_mouse
C4281785	Childhood Absence Epilepsy	disease	BEFREE
C4316903	Absence Seizures	phenotype	CTD_mouse
C4317109	Epileptic Seizures	disease	CTD_mouse
C4317123	Myoclonic Seizures	phenotype	CTD_mouse
C4505436	Generalized Absence Seizures	disease	CTD_mouse

Gene Ontology (GO)/biological pathways

GO:Molecular Function

GO ID	GO Term	Evidence
GO:0005215	transporter activity	TAS
GO:0005515	protein binding	IPI
GO:0005524	ATP binding	IDA
GO:0008559	ATPase-coupled xenobiotic transmembrane transporter activity	IEA
GO:0015562	efflux transmembrane transporter activity	IMP
GO:0015562	efflux transmembrane transporter activity	IDA
GO:0016887	ATPase activity	IDA
GO:0031625	ubiquitin protein ligase binding	IPI
GO:0042626	ATPase-coupled transmembrane transporter activity	IBA
GO:0042910	xenobiotic transmembrane transporter activity	IMP
GO:0042910	xenobiotic transmembrane transporter activity	IDA
GO:0090554	phosphatidylcholine floppase activity	IBA
GO:0090554	phosphatidylcholine floppase activity	IDA
GO:0090555	phosphatidylethanolamine flippase activity	IBA
GO:0090555	phosphatidylethanolamine flippase activity	IDA
GO:0099038	ceramide floppase activity	IBA
GO:0099038	ceramide floppase activity	IDA
GO:0140328	floppase activity	IMP

GO:Biological Process

GO ID	GO Term	Evidence
GO:0000086	G2/M transition of mitotic cell cycle	IDA
GO:0042493	response to drug	TAS
GO:0045332	phospholipid translocation	IBA
GO:0045332	phospholipid translocation	IDA
GO:0047484	regulation of response to osmotic stress	IMP
GO:0055085	transmembrane transport	TAS
GO:0070633	transepithelial transport	IMP
GO:0070633	transepithelial transport	IDA
GO:0072089	stem cell proliferation	IMP
GO:0099040	ceramide translocation	IBA
GO:0099040	ceramide translocation	IDA
GO:0140115	export across plasma membrane	IMP
GO:0140115	export across plasma membrane	IDA
GO:1901529	positive regulation of anion channel activity	IMP
GO:1990962	xenobiotic transport across blood-brain barrier	ISS
GO:1990962	xenobiotic transport across blood-brain barrier	IC
GO:2001225	regulation of chloride transport	IMP

GO:Cellular Component

GO ID	GO Term	Evidence
GO:0005886	plasma membrane	IDA
GO:0005886	plasma membrane	IBA
GO:0005886	plasma membrane	TAS
GO:0009986	cell surface	IDA
GO:0016020	membrane	IDA
GO:0016021	integral component of membrane	IEA
GO:0016324	apical plasma membrane	IDA
GO:0070062	extracellular exosome	HDA
GO:0098591	external side of apical plasma membrane	ISS

Reactome Pathway

Reactome ID	Reactome Term	Evidence
R-HSA-1430728	Metabolism	IEA
R-HSA-2161517	Abacavir transmembrane transport	IEA
R-HSA-2161522	Abacavir transport and metabolism	IEA
R-HSA-382551	Transport of small molecules	TAS
R-HSA-382556	ABC-family proteins mediated transport	TAS

Drugs and compounds information

ID	Drug Name	Action	PubMed
C039775	10,11-dihydro-10-hydroxycarbamazepine	ABCB1 protein results in increased transport of 10,11-dihydro-10-hydroxycarbamazepine	16190932
C095360	10-deacetylpaclitaxel	10-deacetylpaclitaxel binds to ABCB1 protein	29625142
C569670	1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1-yl)-2-hydroxypropan-1-one	ABCB1 protein results in increased transport of 1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1-yl)-2-hydroxypropan-1-one	22696419
C059164	15-hydroxy-5,8,11,13,17-eicosapentaenoic acid	15-hydroxy-5,8,11,13,17-eicosapentaenoic acid affects the expression of ABCB1 mRNA	26984781
C119129	18alpha-glycyrrhetinic acid	18alpha-glycyrrhetinic acid inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	24380838
C097775	1-cyclohexyl-4-(3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)-n-propyl)piperazine	1-cyclohexyl-4-(3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)-n-propyl)piperazine results in decreased activity of ABCB1 protein	21229979
C505382	1-cyclohexyl-4-(3-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl)-piperazine	1-cyclohexyl-4-(3-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl)-piperazine results in decreased expression of ABCB1 protein	16891467
C105351	1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene	[Tretinoin co-treated with Phenylbutyrates co-treated with 1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene] results in increased expression of ABCB1 protein	23284745
D015058	1-Naphthylisothiocyanate	1-Naphthylisothiocyanate results in increased expression of ABCB1 mRNA	17522070
C532162	2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine	ABCB1 protein affects the transport of 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine	20522663
C532162	2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine	Elacridar inhibits the reaction [ABCB1 protein affects the transport of 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine]	20522663
C574037	2-(1-hydroxy-4-oxocyclohexa-2,5-dienyl)pyran-4-one	[2-(1-hydroxy-4-oxocyclohexa-2,5-dienyl)pyran-4-one results in increased susceptibility to Doxorubicin] which results in decreased expression of ABCB1 protein	28987325
C054919	2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene	2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene results in increased expression of ABCB1 mRNA	25542188
C054919	2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene	2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene results in increased expression of ABCB1 protein	25542188
C054917	2,2-(2-chlorophenyl-4'-chlorophenyl)acetic acid	2,2-(2-chlorophenyl-4'-chlorophenyl)acetic acid results in increased expression of ABCB1 mRNA	25542188
C101670	2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate	2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [Digoxin results in increased expression of ABCB1 protein]	19647009
C101670	2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate	2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [Ouabain results in increased expression of ABCB1 protein]	19647009
C085911	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of ABCB1 mRNA	23466342
C085911	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of ABCB1 protein	23466342
C085911	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of ABCB1 protein	27888070
C562251	24-norcholan-2,3,24-tryl-2,3,23-sulfuric acid	24-norcholan-2,3,24-tryl-2,3,23-sulfuric acid results in increased expression of ABCB1 mRNA	21141967
D015073	2-Acetylaminofluorene	2-Acetylaminofluorene results in decreased expression of ABCB1 mRNA	12387747
D015073	2-Acetylaminofluorene	2-Acetylaminofluorene results in increased activity of ABCB1 protein	11960367
D015073	2-Acetylaminofluorene	[2-Acetylaminofluorene results in increased activity of AKT1 protein] which results in increased expression of ABCB1 mRNA	11960367
D015073	2-Acetylaminofluorene	[2-Acetylaminofluorene results in increased activity of RAC1 protein] which results in increased expression of ABCB1 mRNA	11960367
D015073	2-Acetylaminofluorene	2-Acetylaminofluorene results in increased expression of ABCB1 mRNA	11960367
D015073	2-Acetylaminofluorene	[RELA protein binds to NFKB1 protein] affects the reaction [2-Acetylaminofluorene results in increased expression of ABCB1 mRNA]	11960367
D015073	2-Acetylaminofluorene	2-Acetylaminofluorene results in increased expression of ABCB1 mRNA	17303067
D015073	2-Acetylaminofluorene	2-Acetylaminofluorene results in increased expression of ABCB1 protein	17303067
D015073	2-Acetylaminofluorene	Phycocyanin inhibits the reaction [2-Acetylaminofluorene results in increased expression of ABCB1 mRNA]	17303067
D015073	2-Acetylaminofluorene	Phycocyanin inhibits the reaction [2-Acetylaminofluorene results in increased expression of ABCB1 protein]	17303067
D015073	2-Acetylaminofluorene	2-Acetylaminofluorene results in increased expression of ABCB1 mRNA	17669244
C521104	2-methoxy-N-(3-(4-((3-methyl-4-((6-methyl-3-pyridinyl)oxy)phenyl)amino)-6-quinazolinyl)-2-propenyl)acetamide	2-methoxy-N-(3-(4-((3-methyl-4-((6-methyl-3-pyridinyl)oxy)phenyl)amino)-6-quinazolinyl)-2-propenyl)acetamide inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	19223659
C016392	3,3'-diindolylmethane	[3,3'-diindolylmethane results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA	25542144
C016392	3,3'-diindolylmethane	3,3'-diindolylmethane results in increased expression of ABCB1 mRNA	25542144
C016392	3,3'-diindolylmethane	Ketoconazole inhibits the reaction [3,3'-diindolylmethane results in increased expression of ABCB1 mRNA]	25542144
C061213	3',4',7-trihydroxyisoflavone	3',4',7-trihydroxyisoflavone inhibits the reaction [Epirubicin results in increased expression of ABCB1 mRNA]	22914566
C061213	3',4',7-trihydroxyisoflavone	3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mRNA	22914566
C061213	3',4',7-trihydroxyisoflavone	Acetylcysteine inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mRNA]	22914566
C061213	3',4',7-trihydroxyisoflavone	Ascorbic Acid inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mRNA]	22914566
C061213	3',4',7-trihydroxyisoflavone	CAT protein inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mRNA]	22914566
D015104	3,4-Methylenedioxyamphetamine	3,4-Methylenedioxyamphetamine results in increased activity of ABCB1 protein	23273999
C051800	3,4-methylenedioxyethamphetamine	3,4-methylenedioxyethamphetamine results in decreased activity of ABCB1 protein	14690877
C434003	3-(4-methylphenylsulfonyl)-2-propenenitrile	3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Cadmium Chloride results in increased expression of ABCB1]	10636889
C090937	3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole	3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Digoxin results in increased expression of ABCB1 mRNA]	19647009
C090937	3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole	3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Digoxin results in increased expression of ABCB1 protein]	19647009
C090937	3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole	3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Ouabain results in increased expression of ABCB1 mRNA]	19647009
C090937	3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole	3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Ouabain results in increased expression of ABCB1 protein]	19647009
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCB1 protein	23856525
C017906	3-dinitrobenzene	3-dinitrobenzene results in decreased expression of ABCB1 mRNA	16142770
C041477	3-hydroxyflavone	3-hydroxyflavone results in increased expression of ABCB1 mRNA	26238175
C047368	3-methylquercetin	3-methylquercetin results in increased expression of ABCB1 mRNA	26238175
C047368	3-methylquercetin	ABCB1 protein results in increased transport of 3-methylquercetin	15969930
C516284	4-cumylphenol	4-cumylphenol results in increased expression of ABCB1 mRNA	22214767
C015952	4-iodo-2,5-dimethoxyphenylisopropylamine	4-iodo-2,5-dimethoxyphenylisopropylamine results in increased activity of ABCB1 protein	23273999
C000603500	4'-methoxy-1-naphthylfenoterol	4'-methoxy-1-naphthylfenoterol results in decreased expression of ABCB1 protein	27423937
C100230	4-methoxyamphetamine	4-methoxyamphetamine results in decreased activity of ABCB1 protein	14690877
C498826	4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide	ABCB1 protein affects the susceptibility to 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide	28623111
C094782	5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone	5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]	20438634; 20438634;
C094782	5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone	[ABCB1 protein results in decreased susceptibility to Doxorubicin] affects the reaction [5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]]	20438634
C080669	5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one	5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one results in decreased expression of ABCB1 mRNA	23470866
C080669	5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one	5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one results in decreased expression of and results in decreased activity of ABCB1 protein	23470866
C080669	5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one	diacetyldiphenylurea bisguanylhydrazone inhibits the reaction [5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one results in decreased expression of ABCB1 mRNA]	23470866
C058722	5-hydroxy-6,8,11,14,17-eicosapentaenoic acid	5-hydroxy-6,8,11,14,17-eicosapentaenoic acid affects the expression of ABCB1 mRNA	26984781
D000078223	5-Methoxypsoralen	5-Methoxypsoralen results in decreased activity of ABCB1 protein	29079042
D000078223	5-Methoxypsoralen	[5-Methoxypsoralen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of Daunorubicin	29079042
D000078223	5-Methoxypsoralen	5-Methoxypsoralen results in increased expression of ABCB1 mRNA	29079042
D000078223	5-Methoxypsoralen	Verapamil inhibits the reaction [5-Methoxypsoralen results in decreased activity of ABCB1 protein]	29079042
D000078223	5-Methoxypsoralen	Verapamil inhibits the reaction [[5-Methoxypsoralen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of Daunorubicin]	29079042
C000618475	5-oxo-hexahydroquinoline	5-oxo-hexahydroquinoline analog inhibits the reaction [ABCB1 protein results in increased export of Rhodamine 123]	30391378
C000618475	5-oxo-hexahydroquinoline	5-oxo-hexahydroquinoline analog results in decreased activity of ABCB1 protein	30391378
C483321	6-bromoindirubin-3'-oxime	6-bromoindirubin-3'-oxime results in increased expression of ABCB1 mRNA	18624906
C483321	6-bromoindirubin-3'-oxime	6-bromoindirubin-3'-oxime results in increased expression of and results in increased activity of ABCB1 protein	18624906
C550547	6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide	6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide affects the expression of ABCB1 mRNA	29545174
C550547	6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide	6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide affects the expression of ABCB1 protein	29545174
C010643	6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid	6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in decreased expression of ABCB1 mRNA]	15327746
C095088	6-(N-(7-nitro-2,1,3-benzoxadiazol-4-yl)amino)hexanoyl-glucosylceramide	ABCB1 protein results in increased transport of 6-(N-(7-nitro-2,1,3-benzoxadiazol-4-yl)amino)hexanoyl-glucosylceramide	21436125
C580599	6-OH-BDE-47	6-OH-BDE-47 inhibits the reaction [ABCB1 protein results in increased export of Paclitaxel]	28031414
C580599	6-OH-BDE-47	6-OH-BDE-47 results in decreased activity of ABCB1 protein	28031414
C482678	7-hydroxymitragynine	7-hydroxymitragynine results in decreased activity of ABCB1 protein	24841968
C017040	8-azidoadenosine 5'-triphosphate	8-azidoadenosine 5'-triphosphate binds to ABCB1 protein	14978246
C017040	8-azidoadenosine 5'-triphosphate	ABCB1 protein mutant form binds to 8-azidoadenosine 5'-triphosphate	11027628
C017040	8-azidoadenosine 5'-triphosphate	beryllium fluoride promotes the reaction [ABCB1 protein mutant form binds to 8-azidoadenosine 5'-triphosphate]	11027628
C017040	8-azidoadenosine 5'-triphosphate	Disulfiram inhibits the reaction [8-azidoadenosine 5'-triphosphate binds to ABCB1 protein]	14978246
C017040	8-azidoadenosine 5'-triphosphate	fluoroaluminum promotes the reaction [ABCB1 protein mutant form binds to 8-azidoadenosine 5'-triphosphate]	11027628
C017040	8-azidoadenosine 5'-triphosphate	Verapamil promotes the reaction [ABCB1 protein mutant form binds to 8-azidoadenosine 5'-triphosphate]	11027628
C063380	9-((2-phosphonylmethoxy)ethyl)guanine	9-((2-phosphonylmethoxy)ethyl)guanine analog inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	23856525
C048324	abamectin	abamectin inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	25865432
C048324	abamectin	abamectin results in decreased activity of ABCB1 protein	25865432
C000590451	abemaciclib	abemaciclib inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	27816545
C000590451	abemaciclib	abemaciclib inhibits the reaction [ABCB1 protein results in increased export of Rhodamine 123]	27816545
C000590451	abemaciclib	abemaciclib results in decreased activity of ABCB1 protein	27816545
C023710	abietic acid	abietic acid inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D000070	Acebutolol	Acebutolol binds to ABCB1 protein	10783826
D000074	Acenocoumarol	ABCB1 gene polymorphism affects the susceptibility to Acenocoumarol	18021343
D000082	Acetaminophen	ABCB1 protein affects the susceptibility to Acetaminophen	16930294
D000082	Acetaminophen	ABCB1 protein results in increased transport of Acetaminophen	16930294
D000082	Acetaminophen	Acetaminophen promotes the reaction [ABCB1 protein results in decreased uptake of Doxorubicin]	17526808
D000082	Acetaminophen	Acetaminophen results in increased activity of ABCB1 protein	16930294; 17526808;
D000082	Acetaminophen	Acetaminophen results in increased expression of ABCB1 mRNA	26690555
D000082	Acetaminophen	Acetaminophen results in increased expression of ABCB1 protein	16930294; 17627974;
D000082	Acetaminophen	Verapamil inhibits the reaction [Acetaminophen results in increased activity of ABCB1 protein]	16930294; 17526808;
D000082	Acetaminophen	Acetaminophen promotes the reaction [ABCB1 protein results in increased transport of Digoxin]	15276087
D000082	Acetaminophen	Acetaminophen results in increased expression of ABCB1 mRNA	17522070
D000082	Acetaminophen	Acetaminophen results in increased expression of ABCB1 protein	15276087
C043377	acetochlor	ABCB1 protein affects the reaction [acetochlor results in increased susceptibility to Paclitaxel]	18433974
C043377	acetochlor	acetochlor results in increased activity of ABCB1 protein	18433974
C056165	acetovanillone	acetovanillone inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]	18474546
C056165	acetovanillone	acetovanillone inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D000111	Acetylcysteine	Acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of CASP7 protein]	25824409
D000111	Acetylcysteine	Acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of PARP1 protein]	25824409
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mRNA]	22914566
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [formononetin results in increased expression of ABCB1 mRNA]	23867903
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of ABCB1]	10636889
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D000157	Aconitine	ABCB1 affects the transport of Aconitine	23562926
D000157	Aconitine	ABCB1 results in decreased susceptibility to Aconitine	23562926
D000255	Adenosine Triphosphate	ABCB1 protein binds to and results in increased hydrolysis of Adenosine Triphosphate	14978246
D000255	Adenosine Triphosphate	ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate	18829547; 18955043; 22233293; 2900677;
D000255	Adenosine Triphosphate	aurapten promotes the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]	18955043
D000255	Adenosine Triphosphate	[Cobalt results in increased activity of ABCB1 protein] which results in increased hydrolysis of Adenosine Triphosphate	2900677
D000255	Adenosine Triphosphate	Crizotinib promotes the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]	22233293
D000255	Adenosine Triphosphate	Disulfiram affects the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]	14978246
D000255	Adenosine Triphosphate	Lapatinib promotes the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]	18829547
D000255	Adenosine Triphosphate	[Magnesium results in increased activity of ABCB1 protein] which results in increased hydrolysis of Adenosine Triphosphate	2900677
D000255	Adenosine Triphosphate	[Manganese results in increased activity of ABCB1 protein] which results in increased hydrolysis of Adenosine Triphosphate	2900677
D000255	Adenosine Triphosphate	nobiletin promotes the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]	18955043
D016604	Aflatoxin B1	Aflatoxin B1 results in decreased methylation of ABCB1 gene	27153756
D016604	Aflatoxin B1	Aflatoxin B1 results in increased expression of ABCB1 mRNA	27153756
D016604	Aflatoxin B1	Aflatoxin B1 results in increased methylation of ABCB1 intron	30157460
C000188	alachlor	ABCB1 protein affects the reaction [alachlor results in increased susceptibility to Paclitaxel]	18433974
C000188	alachlor	alachlor results in increased activity of ABCB1 protein	18433974
D000450	Aldosterone	ABCB1 protein results in increased secretion of Aldosterone	22464980
D000450	Aldosterone	Aldosterone results in increased expression of ABCB1 mRNA	12387747
D000450	Aldosterone	Elacridar inhibits the reaction [ABCB1 protein results in increased secretion of Aldosterone]	22464980
D000450	Aldosterone	valspodar inhibits the reaction [ABCB1 protein results in increased secretion of Aldosterone]	22464980
C446481	aliskiren	ABCB1 protein affects the susceptibility to aliskiren	24388840
C006452	allicin	allicin inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir]	15266218
C038491	allyl sulfide	allyl sulfide results in increased expression of ABCB1 mRNA	22397993
D000517	alpha-Chlorohydrin	alpha-Chlorohydrin results in decreased expression of ABCB1 protein	17803981
D024502	alpha-Tocopherol	alpha-Tocopherol inhibits the reaction [nickel chloride results in increased expression of ABCB1 protein]	24448832
D000602	Amino Acids, Peptides, and Proteins	Amino Acids, Peptides, and Proteins inhibits the reaction [Carbamazepine results in increased expression of ABCB1 protein]	18473823
D000602	Amino Acids, Peptides, and Proteins	Amino Acids, Peptides, and Proteins inhibits the reaction [Levetiracetam results in increased expression of ABCB1 protein]	18473823
D000602	Amino Acids, Peptides, and Proteins	Amino Acids, Peptides, and Proteins inhibits the reaction [Phenobarbital results in increased expression of ABCB1 protein]	18473823
D000602	Amino Acids, Peptides, and Proteins	Amino Acids, Peptides, and Proteins inhibits the reaction [Phenytoin results in increased expression of ABCB1 protein]	18473823
D000602	Amino Acids, Peptides, and Proteins	Amino Acids, Peptides, and Proteins inhibits the reaction [Tiagabine results in increased expression of ABCB1 protein]	18473823
D000602	Amino Acids, Peptides, and Proteins	Amino Acids, Peptides, and Proteins inhibits the reaction [Topiramate results in increased expression of ABCB1 protein]	18473823
D000638	Amiodarone	Amiodarone inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]	12235267
D000638	Amiodarone	Amiodarone inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]	11231118
D000638	Amiodarone	Amiodarone inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11231118
D000638	Amiodarone	Amiodarone results in decreased activity of ABCB1 protein	11231118
D000638	Amiodarone	Amiodarone affects the expression of ABCB1 mRNA	18355885
D000639	Amitriptyline	Amitriptyline affects the expression of ABCB1 mRNA	18355885
C049148	amorphigenin	amorphigenin affects the activity of ABCB1 protein	15796199
C095108	amprenavir	ABCB1 protein results in increased transport of amprenavir	23976943
C095108	amprenavir	amprenavir binds to ABCB1 protein	23976943
C095108	amprenavir	[Elacridar binds to and results in decreased activity of ABCB1 protein] which results in decreased export of amprenavir	23976943
C098751	AN 204	AN 204 results in increased expression of ABCB1 mRNA	16047355; 16051478;
C416531	AN 215	AN 215 results in increased expression of ABCB1 mRNA	16051478
C110845	AN 238	AN 238 results in increased expression of ABCB1 mRNA	16047355
C010680	antibiotic G 418	ABCB1 protein results in increased transport of antibiotic G 418	20018165
C010680	antibiotic G 418	antibiotic G 418 results in decreased expression of ABCB1 mRNA	20018165
D000927	Anticonvulsants	ABCB1 protein affects the susceptibility to Anticonvulsants	18408562
D000927	Anticonvulsants	ABCB1 protein results in decreased susceptibility to Anticonvulsants	15581025
C473343	antofine	antofine results in decreased expression of ABCB1 mRNA	22120505
C473343	antofine	antofine results in decreased expression of ABCB1 protein	22120505
C102351	apicidin	ABCB1 protein results in decreased susceptibility to apicidin	16049968
D001151	Arsenic	ABCB1 protein affects the susceptibility to Arsenic	29951962
D001151	Arsenic	ABCB1 protein results in increased export of Arsenic	12387749
D000077237	Arsenic Trioxide	Arsenic Trioxide results in decreased expression of ABCB1 mRNA	15979894; 22214486; 22959511;
D000077237	Arsenic Trioxide	Arsenic Trioxide results in decreased expression of ABCB1 protein	14642128; 15634520; 15844663; 15979894; 22959511; 27840903;
D000077237	Arsenic Trioxide	Arsenic Trioxide results in increased expression of ABCB1 mRNA	21945491
D000077237	Arsenic Trioxide	Arsenic Trioxide results in increased expression of ABCB1 protein	29274627
D000077237	Arsenic Trioxide	Arsenic Trioxide results in increased activity of ABCB1 protein	22580103
D000077237	Arsenic Trioxide	Arsenic Trioxide results in increased expression of ABCB1 mRNA	22580103
D000077237	Arsenic Trioxide	Arsenic Trioxide affects the expression of ABCB1 mRNA	30041384
C031327	artemisinine	artemisinine results in decreased activity of ABCB1 protein	15761118
C031327	artemisinine	artemisinine results in increased expression of ABCB1 mRNA	15761118
C078098	ar-turmerone	ar-turmerone results in increased expression of ABCB1 mRNA	22181075
D017638	Asbestos, Crocidolite	Asbestos, Crocidolite results in increased expression of ABCB1 protein	18385176
D017638	Asbestos, Crocidolite	ferric nitrilotriacetate inhibits the reaction [Asbestos, Crocidolite results in increased expression of ABCB1 protein]	18385176
D001205	Ascorbic Acid	Ascorbic Acid inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mRNA]	22914566
C022870	asoxime chloride	[tariquidar results in decreased activity of ABCB1 protein] which results in increased abundance of asoxime chloride	21600273
D001241	Aspirin	Aspirin results in increased activity of ABCB1 protein	19840843
D001241	Aspirin	Aspirin results in increased expression of ABCB1 mRNA	21900887
D001241	Aspirin	Aspirin results in increased expression of ABCB1 protein	21900887
D001241	Aspirin	[Aspirin results in increased expression of ABCB1 protein] which results in decreased uptake of Clopidogrel	21900887
D000069446	Atazanavir Sulfate	ABCB1 protein results in increased transport of Atazanavir Sulfate	29859254
D000069059	Atorvastatin	ABCB1 alternative form affects the reaction [CYP3A4 polymorphism affects the susceptibility to Atorvastatin]	19802823
D000069059	Atorvastatin	ABCB1 protein results in increased transport of Atorvastatin	10751037; 15616150;
D000069059	Atorvastatin	ABCB1 protein results in increased transport of Atorvastatin analog	15616150
D000069059	Atorvastatin	Atorvastatin analog inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	15616150
D000069059	Atorvastatin	Atorvastatin analog results in decreased activity of ABCB1 protein	15616150
D000069059	Atorvastatin	ABCB1 results in increased transport of Atorvastatin	19802823
C105832	aurapten	aurapten promotes the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]	18955043
C105832	aurapten	aurapten promotes the reaction [ABCB1 protein results in increased import of Daunorubicin]	18955043
C019264	avermectin	[avermectin results in increased abundance of Calcium] which results in increased expression of ABCB1 protein	23523950
C019264	avermectin	avermectin results in increased expression of and results in increased activity of ABCB1 protein	23523950
C019264	avermectin	[Cyclosporine results in decreased activity of ABCB1 protein] inhibits the reaction [avermectin results in increased abundance of Calcium]	23523950
C019264	avermectin	Niflumic Acid inhibits the reaction [[avermectin results in increased abundance of Calcium] which results in increased expression of ABCB1 protein]	23523950
C019264	avermectin	pyrrolidine dithiocarbamic acid inhibits the reaction [avermectin results in increased expression of ABCB1 protein]	23523950
C019264	avermectin	Trifluoperazine inhibits the reaction [avermectin results in increased expression of ABCB1 protein]	23523950
C019264	avermectin	Verapamil inhibits the reaction [[avermectin results in increased abundance of Calcium] which results in increased expression of ABCB1 protein]	23523950
C100095	azacyclonol	ABCB1 protein affects the transport of azacyclonol	10350002
D001379	Azathioprine	ABCB1 gene polymorphism affects the susceptibility to Azathioprine	17262810
C020976	azelastine	azelastine inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]	11231118
C020976	azelastine	azelastine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11231118
C020976	azelastine	azelastine results in decreased activity of ABCB1 protein	11231118
C041130	azidopine	azidopine binds to ABCB1 protein	14978246
C041130	azidopine	Disulfiram inhibits the reaction [azidopine binds to ABCB1 protein]	14978246
C041552	azidoprazosin	azidoprazosin binds to ABCB1 protein	14978246; 18829547;
C041552	azidoprazosin	Disulfiram inhibits the reaction [azidoprazosin binds to ABCB1 protein]	14978246
C041552	azidoprazosin	Lapatinib inhibits the reaction [azidoprazosin binds to ABCB1 protein]	18829547
C041552	azidoprazosin	[Tacrolimus binds to ABCB1 protein] inhibits the reaction [azidoprazosin binds to ABCB1 protein]	1381629
C006680	baicalein	baicalein results in increased expression of ABCB1 mRNA	25625231
C051168	basil oil	basil oil results in increased expression of ABCB1 mRNA	30071242
C004456	beauvericin	beauvericin results in decreased activity of ABCB1 protein	27474255
C004456	beauvericin	beauvericin results in increased expression of ABCB1 mRNA	27474255
D001507	Beclomethasone	ABCB1 protein results in increased secretion of Beclomethasone	22464980
D001507	Beclomethasone	Beclomethasone inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	16442095
D001507	Beclomethasone	Beclomethasone inhibits the reaction [ABCB1 protein results in increased export of fluorexon]	16442095
D001507	Beclomethasone	Beclomethasone results in increased expression of ABCB1 mRNA	15370884
D001507	Beclomethasone	Beclomethasone results in increased expression of ABCB1 protein	22464980
D001507	Beclomethasone	Elacridar inhibits the reaction [ABCB1 protein results in increased secretion of Beclomethasone]	22464980
D001507	Beclomethasone	valspodar inhibits the reaction [ABCB1 protein results in increased secretion of Beclomethasone]	22464980
C061004	benidipine	benidipine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
D001554	Benzene	ABCB1 affects the susceptibility to Benzene	21619790
D001554	Benzene	Benzene results in increased expression of ABCB1 mRNA	19162166
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of ABCB1 mRNA	15566942; 16545412; 17408918; 21632981; 26238291;
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of ABCB1 mRNA	11096091
C026487	benzo(e)pyrene	benzo(e)pyrene results in increased expression of ABCB1 mRNA	17408918
C022921	benzo(k)fluoranthene	benzo(k)fluoranthene results in increased expression of ABCB1 mRNA	15566942
C047307	benzoylaconine	ABCB1 protein results in increased transport of benzoylaconine	23200901
C047307	benzoylaconine	[Cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylaconine	23200901
C047307	benzoylaconine	[Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylaconine	23200901
C479202	benzoylhypaconine	ABCB1 protein results in increased transport of benzoylhypaconine	23200901
C479202	benzoylhypaconine	[Cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylhypaconine	23200901
C479202	benzoylhypaconine	[Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylhypaconine	23200901
C085283	benzoylmesaconine	ABCB1 protein results in increased transport of benzoylmesaconine	23200901
C085283	benzoylmesaconine	[Cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylmesaconine	23200901
C085283	benzoylmesaconine	[Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylmesaconine	23200901
D015764	Bepridil	Bepridil inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
C068337	bergamottin	bergamottin results in increased expression of ABCB1 mRNA	19148864
C068337	bergamottin	bergamottin results in increased expression of ABCB1 protein	19148864
C035982	beryllium fluoride	beryllium fluoride promotes the reaction [ABCB1 protein mutant form binds to 8-azidoadenosine 5'-triphosphate]	11027628
C010789	beta-pinene	beta-pinene inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D001629	Bezafibrate	Bezafibrate results in decreased expression of ABCB1 mRNA	21872554
D001629	Bezafibrate	Bezafibrate results in increased expression of ABCB1 mRNA	21872554
C543008	bis(4-hydroxyphenyl)sulfone	ABCB1 promoter SNP affects the reaction [bis(4-hydroxyphenyl)sulfone affects the expression of ABCB1 mRNA]	30240697; 30240697;
C543008	bis(4-hydroxyphenyl)sulfone	bis(4-hydroxyphenyl)sulfone affects the expression of ABCB1 mRNA	30240697
C017807	bisbenzimide ethoxide trihydrochloride	abamectin inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	25865432
C017807	bisbenzimide ethoxide trihydrochloride	ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride	25865432
C017807	bisbenzimide ethoxide trihydrochloride	emamectin inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	25865432
C017807	bisbenzimide ethoxide trihydrochloride	Ivermectin inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	25865432
C017807	bisbenzimide ethoxide trihydrochloride	9-((2-phosphonylmethoxy)ethyl)guanine analog inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	23856525
D017298	Bisoprolol	ABCB1 protein results in increased transport of Bisoprolol	16671962
D017298	Bisoprolol	Bisoprolol inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	16671962
D017298	Bisoprolol	valspodar inhibits the reaction [ABCB1 protein results in increased transport of Bisoprolol]	16671962
C006780	bisphenol A	ABCB1 promoter SNP affects the reaction [bisphenol A results in increased expression of ABCB1 mRNA]	30240697; 30240697;
C006780	bisphenol A	bisphenol A affects the expression of ABCB1 mRNA	24793377; 30903817;
C006780	bisphenol A	bisphenol A results in increased expression of ABCB1 mRNA	22214767; 29960846; 30240697;
C006780	bisphenol A	bisphenol A results in increased expression of ABCB1 mRNA	27569056
C006780	bisphenol A	bisphenol A results in increased expression of ABCB1 mRNA	25127357
C006780	bisphenol A	bisphenol A results in decreased expression of ABCB1 mRNA	25181051
C492482	bisphenol B	bisphenol B results in increased expression of ABCB1 mRNA	22214767
C504983	BMS 536924	BMS 536924 results in decreased expression of ABCB1 protein	26394120
D000069286	Bortezomib	ATP2A1 protein affects the reaction [Bortezomib results in decreased expression of ABCB1]	25576094
D000069286	Bortezomib	Bortezomib results in decreased activity of ABCB1 protein	25576094
D000069286	Bortezomib	Bortezomib results in decreased expression of ABCB1	25576094
D000077300	Bosentan	Bosentan results in decreased expression of ABCB1 mRNA	28369585
D001971	Bromocriptine	Bromocriptine results in increased expression of ABCB1 protein	9111066
D001971	Bromocriptine	Clozapine inhibits the reaction [Bromocriptine results in increased expression of ABCB1 protein]	9111066
D001971	Bromocriptine	Spiperone inhibits the reaction [Bromocriptine results in increased expression of ABCB1 protein]	9111066
C514835	bromotetrandrine	bromotetrandrine results in decreased expression of ABCB1 protein	15378274
C514835	bromotetrandrine	[Daunorubicin co-treated with bromotetrandrine co-treated with Magnetite Nanoparticles] results in decreased expression of ABCB1 mRNA	22114476
C514835	bromotetrandrine	[Daunorubicin co-treated with bromotetrandrine] results in decreased expression of ABCB1 mRNA	22114476
D019819	Budesonide	Budesonide results in increased expression of ABCB1 protein	22464980
C022777	bufalin	bufalin inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	23104431
C018475	butyraldehyde	butyraldehyde results in increased expression of ABCB1 mRNA	26079696
D002087	Butyrates	Butyrates results in increased expression of ABCB1 mRNA	15711177
D020148	Butyric Acid	Butyric Acid results in increased expression of ABCB1 mRNA	15711177
D002104	Cadmium	Cadmium results in increased expression of ABCB1 protein	15084411
D002104	Cadmium	ABCB1 protein inhibits the reaction [Cadmium results in increased abundance of Ceramides]	21436125
D002104	Cadmium	ABCB1 protein results in decreased susceptibility to Cadmium	21436125
D002104	Cadmium	Cadmium inhibits the reaction [Magnesium results in increased activity of ABCB1 protein]	2900677
D002104	Cadmium	valspodar inhibits the reaction [ABCB1 protein results in decreased susceptibility to Cadmium]	21436125
D019256	Cadmium Chloride	Cadmium Chloride results in increased expression of ABCB1 mRNA	1967174
D019256	Cadmium Chloride	Cadmium Chloride results in increased expression of ABCB1 mRNA	23741332
D019256	Cadmium Chloride	Cadmium Chloride results in increased expression of ABCB1 mRNA	25956639
D019256	Cadmium Chloride	Cadmium Chloride results in increased transport of ABCB1 protein	25956639
D019256	Cadmium Chloride	titanium dioxide inhibits the reaction [Cadmium Chloride results in increased expression of ABCB1 mRNA]	25956639
D019256	Cadmium Chloride	Cadmium Chloride results in increased expression of ABCB1 mRNA	18804290
D019256	Cadmium Chloride	Cadmium Chloride results in increased activity of ABCB1 protein	22580103
D019256	Cadmium Chloride	3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Cadmium Chloride results in increased expression of ABCB1]	10636889
D019256	Cadmium Chloride	ABCB1 results in decreased susceptibility to Cadmium Chloride	10636889
D019256	Cadmium Chloride	Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of ABCB1]	10636889
D019256	Cadmium Chloride	Cadmium Chloride promotes the reaction [TCF4 protein binds to ABCB1 promoter]	20459685
D019256	Cadmium Chloride	Cadmium Chloride results in increased expression of ABCB1	10636889
D019256	Cadmium Chloride	Cyclosporine inhibits the reaction [ABCB1 results in decreased susceptibility to Cadmium Chloride]	10636889
D019256	Cadmium Chloride	pyrrolidine dithiocarbamic acid inhibits the reaction [Cadmium Chloride results in increased expression of ABCB1]	10636889
D019256	Cadmium Chloride	valspodar inhibits the reaction [ABCB1 results in decreased susceptibility to Cadmium Chloride]	10636889
D019256	Cadmium Chloride	Verapamil inhibits the reaction [ABCB1 results in decreased susceptibility to Cadmium Chloride]	10636889
D019256	Cadmium Chloride	Cadmium Chloride affects the expression of ABCB1 mRNA	30041384
C085925	calcein AM	ABCB1 protein results in increased transport of calcein AM	26929997
C085925	calcein AM	[musk ketone results in decreased activity of ABCB1 protein] which results in decreased export of calcein AM	26929997
C085925	calcein AM	[Pentachlorophenol results in decreased activity of ABCB1 protein] which results in decreased export of calcein AM	26929997
C085925	calcein AM	[reversin 205 results in decreased activity of ABCB1 protein] which results in decreased export of calcein AM	26929997
C085925	calcein AM	[Verapamil results in decreased activity of ABCB1 protein] which results in decreased export of calcein AM	26929997
C085925	calcein AM	2-methoxy-N-(3-(4-((3-methyl-4-((6-methyl-3-pyridinyl)oxy)phenyl)amino)-6-quinazolinyl)-2-propenyl)acetamide inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	19223659
C085925	calcein AM	ABCB1 protein affects the export of calcein AM	10617675
C085925	calcein AM	ABCB1 protein affects the reaction [Mifepristone results in decreased transport of calcein AM]	30217652
C085925	calcein AM	ABCB1 protein affects the reaction [zosuquidar trihydrochloride results in decreased transport of calcein AM]	30217652
C085925	calcein AM	ABCB1 protein results in increased export of calcein AM	29174985
C085925	calcein AM	ABCB1 protein results in increased secretion of calcein AM	16121039
C085925	calcein AM	ABCB1 protein results in increased transport of calcein AM	15616150; 19223659; 21783720;
C085925	calcein AM	Atorvastatin analog inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	15616150
C085925	calcein AM	calcein AM results in increased activity of ABCB1 protein mutant form	12711602
C085925	calcein AM	chlorpyrifos-methyl affects the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
C085925	calcein AM	Cyclosporine inhibits the reaction [ABCB1 protein affects the export of calcein AM]	10617675
C085925	calcein AM	deoxynivalenol inhibits the reaction [valspodar inhibits the reaction [ABCB1 protein results in increased export of calcein AM]]	29174985
C085925	calcein AM	Diazinon inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
C085925	calcein AM	Diazinon promotes the reaction [Endosulfan inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C085925	calcein AM	Diazinon promotes the reaction [phosalone inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C085925	calcein AM	Diazinon promotes the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C085925	calcein AM	Diazinon promotes the reaction [Verapamil inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C085925	calcein AM	[Endosulfan co-treated with Verapamil] inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
C085925	calcein AM	Endosulfan inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
C085925	calcein AM	Endosulfan inhibits the reaction [phosalone inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C085925	calcein AM	Endosulfan promotes the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C085925	calcein AM	fenoxycarb inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
C085925	calcein AM	fenvalerate inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
C085925	calcein AM	Lovastatin analog inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	15616150
C085925	calcein AM	[phosalone co-treated with Verapamil] inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
C085925	calcein AM	phosalone inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
C085925	calcein AM	phosalone inhibits the reaction [Endosulfan inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C085925	calcein AM	phosalone inhibits the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C085925	calcein AM	propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
C085925	calcein AM	propiconazole inhibits the reaction [phosalone inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C085925	calcein AM	propiconazole promotes the reaction [Endosulfan inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C085925	calcein AM	propiconazole promotes the reaction [Verapamil inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C085925	calcein AM	Reserpine inhibits the reaction [ABCB1 protein affects the export of calcein AM]	10617675
C085925	calcein AM	Simvastatin analog inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	15616150
C085925	calcein AM	sodium arsenite promotes the reaction [ABCB1 protein results in increased secretion of calcein AM]	16121039
C085925	calcein AM	valspodar inhibits the reaction [ABCB1 protein results in increased export of calcein AM]	29174985
C085925	calcein AM	[Verapamil binds to and results in decreased activity of ABCB1 protein] inhibits the reaction [sodium arsenite promotes the reaction [ABCB1 protein results in increased secretion of calcein AM]]	16121039
C085925	calcein AM	Verapamil inhibits the reaction [ABCB1 protein results in increased export of calcein AM]	29174985
C085925	calcein AM	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
C085925	calcein AM	Verapamil promotes the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C085925	calcein AM	ABCB1 protein results in increased export of calcein AM analog	25542188
D002117	Calcitriol	Calcitriol results in decreased activity of ABCB1 protein	12387747
D002117	Calcitriol	Calcitriol results in increased expression of ABCB1 mRNA	12387747; 19460946; 27107558;
D002117	Calcitriol	Calcitriol results in increased expression of ABCB1 protein	26366751
D002117	Calcitriol	VDR protein promotes the reaction [Calcitriol results in increased expression of ABCB1 mRNA]	19460946
D002118	Calcium	[avermectin results in increased abundance of Calcium] which results in increased expression of ABCB1 protein	23523950
D002118	Calcium	[Cyclosporine results in decreased activity of ABCB1 protein] inhibits the reaction [avermectin results in increased abundance of Calcium]	23523950
D002118	Calcium	Niflumic Acid inhibits the reaction [[avermectin results in increased abundance of Calcium] which results in increased expression of ABCB1 protein]	23523950
D002118	Calcium	Verapamil inhibits the reaction [[avermectin results in increased abundance of Calcium] which results in increased expression of ABCB1 protein]	23523950
D002118	Calcium	Calcium deficiency inhibits the reaction [ABCB1 protein results in increased export of Xanthenes]	25862123
D002118	Calcium	Calcium inhibits the reaction [Magnesium results in increased activity of ABCB1 protein]	2900677
C510718	cambinol	cambinol affects the expression of ABCB1 mRNA	29545174
C510718	cambinol	cambinol affects the expression of ABCB1 protein	29545174
D002166	Camptothecin	Camptothecin inhibits the reaction [Rifampin results in increased expression of ABCB1 mRNA]	29356861
D002166	Camptothecin	Camptothecin results in decreased expression of ABCB1 mRNA	29356861
D002166	Camptothecin	Camptothecin results in decreased expression of ABCB1 protein	10692111
C100098	cannogenin thevetoside	cannogenin thevetoside inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	23104431
D002211	Capsaicin	Capsaicin affects the reaction [ABCB1 protein results in increased export of Digoxin]	16674925
D002211	Capsaicin	Capsaicin results in increased expression of ABCB1 mRNA	16674925
D002211	Capsaicin	Capsaicin results in increased expression of ABCB1 protein	16674925
C104525	caraway oil	caraway oil results in increased expression of ABCB1 mRNA	30071242
D002220	Carbamazepine	Carbamazepine results in decreased expression of ABCB1 mRNA	21872554
D002220	Carbamazepine	ABCB1 gene polymorphism affects the susceptibility to Carbamazepine	16753003
D002220	Carbamazepine	ABCB1 protein affects the susceptibility to Carbamazepine	14749549; 17376120;
D002220	Carbamazepine	ABCB1 protein affects the transport of Carbamazepine	17376120
D002220	Carbamazepine	Carbamazepine results in decreased activity of ABCB1 protein	18408562
D002220	Carbamazepine	Carbamazepine results in increased expression of ABCB1 mRNA	15371980; 16842400;
D002220	Carbamazepine	Carbamazepine results in increased expression of ABCB1 protein	16842400
D002220	Carbamazepine	Carbamazepine results in decreased expression of ABCB1 mRNA	19632730
D002220	Carbamazepine	Amino Acids, Peptides, and Proteins inhibits the reaction [Carbamazepine results in increased expression of ABCB1 protein]	18473823
D002220	Carbamazepine	Carbamazepine results in increased expression of ABCB1 protein	15569486; 18473823;
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of ABCB1 mRNA	15120965
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of ABCB1 mRNA	17522070
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of ABCB1 protein	12642476
D016190	Carboplatin	Carboplatin results in decreased expression of ABCB1 mRNA	27692344
D016190	Carboplatin	Carboplatin results in decreased expression of ABCB1 protein	27692344
D002298	Cardenolides	Cardenolides inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	23104431
D002330	Carmustine	Carmustine results in increased expression of ABCB1 protein	15239124
D002330	Carmustine	[MGMT protein co-treated with ABCB1 protein] results in decreased susceptibility to Carmustine	11792417
D002330	Carmustine	[MGMT protein mutant form co-treated with ABCB1 protein] results in decreased susceptibility to [Carmustine co-treated with O(6)-benzylguanine]	16733832
D000077261	Carvedilol	ABCB1 protein results in increased transport of Carvedilol	16671962
D000077261	Carvedilol	Carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]	12708479
D000077261	Carvedilol	[Carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]] which results in decreased susceptibility to Daunorubicin	12708479
D000077261	Carvedilol	Carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100; 16671962;
D000077261	Carvedilol	Carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Doxorubicin]	12708479
D000077261	Carvedilol	[Carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Doxorubicin]] which results in decreased susceptibility to Doxorubicin	12708479
D000077261	Carvedilol	Carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Paclitaxel]	12708479
D000077261	Carvedilol	[Carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Paclitaxel]] which results in decreased susceptibility to Paclitaxel	12708479
D000077261	Carvedilol	Carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Vinblastine]	12708479
D000077261	Carvedilol	[Carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Vinblastine]] which results in decreased susceptibility to Vinblastine	12708479
D000077261	Carvedilol	Carvedilol results in decreased activity of ABCB1 protein	10571255
D000077261	Carvedilol	[Carvedilol results in decreased activity of ABCB1 protein] which results in increased susceptibility to Doxorubicin	10571255
D000077261	Carvedilol	[Carvedilol results in decreased activity of ABCB1 protein] which results in increased uptake of fluorexon	10571255
D000077261	Carvedilol	valspodar inhibits the reaction [ABCB1 protein results in increased transport of Carvedilol]	16671962
D000077261	Carvedilol	[Cyclosporine results in decreased activity of ABCB1 protein] which results in increased uptake of Carvedilol	17609666
D000077261	Carvedilol	Carvedilol binds to ABCB1 protein	10783826
D000077261	Carvedilol	Carvedilol metabolite binds to ABCB1 protein	10783826
D000068579	Celecoxib	Celecoxib results in decreased expression of ABCB1 protein	21745461
D000068579	Celecoxib	[Celecoxib results in decreased expression of ABCB1] which results in increased susceptibility to Etoposide	19562670
D000068579	Celecoxib	[Celecoxib results in decreased expression of ABCB1] which results in increased susceptibility to Tamoxifen	19562670
D000068579	Celecoxib	Celecoxib results in increased expression of ABCB1 mRNA	21745461
D000068579	Celecoxib	Celecoxib results in increased methylation of ABCB1 promoter	19562670
D000068579	Celecoxib	ABCB1 results in increased susceptibility to Celecoxib	17510421
D000068579	Celecoxib	Celecoxib results in decreased expression of ABCB1	17510421
D002491	Central Nervous System Agents	Central Nervous System Agents results in increased activity of ABCB1 protein	23273999
C567989	CEP 33779	ABCB1 protein affects the reaction [CEP 33779 results in decreased phosphorylation of STAT3 protein]	25058526
C567989	CEP 33779	CEP 33779 inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	25058526
C567989	CEP 33779	CEP 33779 inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	25058526
C567989	CEP 33779	CEP 33779 inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]	25058526
C567989	CEP 33779	CEP 33779 inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	25058526
C567989	CEP 33779	CEP 33779 inhibits the reaction [ABCB1 protein results in increased export of Rhodamine 123]	25058526
C567989	CEP 33779	CEP 33779 results in decreased activity of ABCB1 protein	28669723
C567989	CEP 33779	CEP 33779 results in increased activity of ABCB1 protein	25058526
C006947	cepharanthine	cepharanthine results in decreased activity of ABCB1 protein	15958061
D002518	Ceramides	ABCB1 protein inhibits the reaction [Cadmium results in increased abundance of Ceramides]	21436125
C086276	cerivastatin	ABCB1 protein affects the export of cerivastatin	15901800
D017332	Cetirizine	ABCB1 protein results in increased export of Cetirizine	12584158
D002699	Chlorambucil	Chlorambucil results in increased expression of ABCB1 protein	15239124
C084597	chlorcyclizine	ABCB1 protein affects the transport of chlorcyclizine	15666293
D002706	Chlordan	Chlordan results in increased expression of ABCB1 mRNA	24464585
D007631	Chlordecone	Chlordecone results in decreased activity of ABCB1 protein	24464585
D002725	Chloroform	Chloroform results in increased expression of ABCB1 mRNA	15120965
D002725	Chloroform	Chloroform results in increased expression of ABCB1 mRNA	17522070
D002738	Chloroquine	Chloroquine results in decreased expression of ABCB1 mRNA	27692344
D002738	Chloroquine	Chloroquine results in decreased expression of ABCB1 protein	27692344
D002744	Chlorpheniramine	ABCB1 protein affects the transport of Chlorpheniramine	15666293
D002746	Chlorpromazine	Chlorpromazine analog results in increased expression of ABCB1 mRNA	15924885
D002746	Chlorpromazine	Chlorpromazine results in decreased activity of ABCB1 protein	16810505
D004390	Chlorpyrifos	Chlorpyrifos binds to ABCB1 protein	8917702
D004390	Chlorpyrifos	Chlorpyrifos inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	8917702
D004390	Chlorpyrifos	Chlorpyrifos results in increased expression of ABCB1 mRNA	28549829
D004390	Chlorpyrifos	Chlorpyrifos results in increased expression of ABCB1 protein	28549829
C007031	chlorpyrifos-methyl	chlorpyrifos-methyl affects the activity of ABCB1 protein	21783720
C007031	chlorpyrifos-methyl	chlorpyrifos-methyl affects the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
C561233	cholan-2,3,24-tryl-2,3,24-trisulfate	cholan-2,3,24-tryl-2,3,24-trisulfate results in increased expression of ABCB1 mRNA	21141967
D002794	Choline	[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCB1 mRNA	24384915
D002794	Choline	[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCB1 protein	24384915
C031180	chrysene	chrysene results in increased expression of ABCB1 mRNA	15566942
C043561	chrysin	chrysin affects the activity of ABCB1 protein	15796199
C043561	chrysin	chrysin results in decreased activity of ABCB1 protein	20457140
C043561	chrysin	[chrysin results in decreased activity of ABCB1 protein] which results in decreased export of Topotecan	20457140
C043561	chrysin	chrysin results in increased expression of ABCB1 protein	20457140
C472594	chrysophsin	[Epirubicin analog co-treated with chrysophsin analog] results in increased expression of ABCB1 mRNA	26335193
C472594	chrysophsin	[Epirubicin co-treated with chrysophsin] results in increased expression of ABCB1 mRNA	26335193
C120481	ciclesonide	ciclesonide results in increased expression of ABCB1 protein	22464980
D015377	Cilastatin	Cilastatin inhibits the reaction [Vancomycin results in decreased expression of and affects the localization of ABCB1 protein]	28549670
D015377	Cilastatin	Cilastatin results in increased expression of and affects the localization of ABCB1 protein	28549670
C010086	cinchonine	cinchonine analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Docetaxel]	20196146
C010086	cinchonine	cinchonine analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	20196146
C010086	cinchonine	cinchonine analog results in decreased expression of ABCB1 protein	20196146
C010086	cinchonine	cinchonine inhibits the reaction [ABCB1 protein results in decreased susceptibility to Docetaxel]	20196146
C010086	cinchonine	cinchonine inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	20196146
C010086	cinchonine	cinchonine results in decreased expression of ABCB1 protein	20196146
C510046	cinnamon oil, bark	cinnamon oil, bark results in increased expression of ABCB1 mRNA	30071242
D002945	Cisplatin	ABCB1 affects the reaction [HIF1A affects the susceptibility to Cisplatin]	21964646
D002945	Cisplatin	ABCB1 affects the susceptibility to Cisplatin	15756446
D002945	Cisplatin	ABCB1 gene polymorphism affects the susceptibility to Cisplatin	16785472
D002945	Cisplatin	ABCB1 gene SNP affects the susceptibility to [Cisplatin co-treated with Fluorouracil]	21332314
D002945	Cisplatin	ABCB1 protein inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein]	22269388
D002945	Cisplatin	ABCB1 protein inhibits the reaction [Cisplatin results in increased activity of and results in increased cleavage of CASP3 protein]	22269388
D002945	Cisplatin	ABCB1 protein inhibits the reaction [Cisplatin results in increased activity of CASP9 protein]	22269388
D002945	Cisplatin	ABCB1 protein promotes the reaction [Cisplatin results in increased expression of TRP53 protein]	22269388
D002945	Cisplatin	ABCB1 protein results in decreased susceptibility to Cisplatin	15990222; 22269388;
D002945	Cisplatin	Cisplatin promotes the reaction [[APEX1 protein modified form promotes the reaction [YBX1 protein binds to EP300 protein]] which binds to ABCB1 promoter]	20856196
D002945	Cisplatin	[Cisplatin results in increased acetylation of APEX1 protein] promotes the reaction [APEX1 protein modified form binds to ABCB1 promoter]	20856196
D002945	Cisplatin	[Cisplatin results in increased acetylation of APEX1 protein] promotes the reaction [[APEX1 protein modified form binds to ABCB1 promoter] which results in increased expression of ABCB1 mRNA]	20856196; 20856196;
D002945	Cisplatin	Cisplatin results in increased expression of ABCB1 mRNA	15650019
D002945	Cisplatin	Cisplatin results in increased expression of ABCB1 protein	15239124; 15650019; 15990222; 27840903; 30452898;
D002945	Cisplatin	[CXCL8 results in increased expression of ABCB1 mRNA] which results in decreased susceptibility to Cisplatin	21742513
D002945	Cisplatin	[CXCL8 results in increased expression of ABCB1 protein] which results in decreased susceptibility to Cisplatin	21742513
D002945	Cisplatin	Omeprazole promotes the reaction [Cisplatin results in increased expression of ABCB1 protein]	30452898
D002945	Cisplatin	[Paclitaxel results in increased expression of ABCB1] which results in decreased susceptibility to Cisplatin	21833476
D002945	Cisplatin	ABCB1 protein results in decreased susceptibility to Cisplatin	22269388
D002945	Cisplatin	ABCB1 protein results in decreased susceptibility to Cisplatin	11455017
D002945	Cisplatin	[Diethylnitrosamine co-treated with Cisplatin] results in increased expression of ABCB1 protein	11818250
D002945	Cisplatin	Cisplatin inhibits the reaction [ABCB1 protein results in increased susceptibility to NSC73306]	24800945
C108217	citronellal	citronellal inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
C108217	citronellal	citronellal results in decreased activity of ABCB1 protein	15890377
C108217	citronellal	[citronellal results in decreased activity of ABCB1 protein] which results in decreased export of Digoxin	15890377
C007078	citronellol	citronellol inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
C007078	citronellol	citronellol results in decreased activity of ABCB1 protein	15890377
C007078	citronellol	[citronellol results in decreased activity of ABCB1 protein] which results in decreased export of Digoxin	15890377
C504653	CJX1, amlodipine derivative	CJX1, amlodipine derivative inhibits the reaction [ABCB1 protein results in decreased secretion of Doxorubicin]	15967469
C504653	CJX1, amlodipine derivative	CJX1, amlodipine derivative results in decreased activity of ABCB1 protein	15967469
C523261	CJY compound	CJY compound results in decreased activity of ABCB1 protein	17637197
D002994	Clofibrate	Clofibrate results in decreased expression of ABCB1 mRNA	19224547
D002995	Clofibric Acid	Clofibric Acid results in increased expression of ABCB1 mRNA	22559005
D002997	Clomipramine	Clomipramine affects the expression of ABCB1 mRNA	18355885
D000077144	Clopidogrel	ABCB1 gene affects the reaction [CYP2C19 gene affects the susceptibility to Clopidogrel]	19934793
D000077144	Clopidogrel	ABCB1 gene affects the susceptibility to Clopidogrel	17112805
D000077144	Clopidogrel	ABCB1 gene polymorphism affects the susceptibility to Clopidogrel	20180610
D000077144	Clopidogrel	ABCB1 gene SNP affects the susceptibility to Clopidogrel	19106083
D000077144	Clopidogrel	ABCB1 protein results in decreased uptake of Clopidogrel	17112805
D000077144	Clopidogrel	ABCB1 protein results in increased secretion of Clopidogrel	17112805
D000077144	Clopidogrel	Clopidogrel results in decreased activity of ABCB1 protein	17112805
D000077144	Clopidogrel	Clopidogrel results in decreased expression of ABCB1 mRNA	17112805
D000077144	Clopidogrel	Clopidogrel results in decreased expression of ABCB1 protein	17112805
D000077144	Clopidogrel	[Aspirin results in increased expression of ABCB1 protein] which results in decreased uptake of Clopidogrel	21900887
D003022	Clotrimazole	Clotrimazole results in decreased expression of ABCB1 mRNA	22559005
D003022	Clotrimazole	Clotrimazole binds to ABCB1 protein	8917702
D003022	Clotrimazole	Clotrimazole inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	8917702
D003022	Clotrimazole	Clotrimazole inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]	12235267
D003022	Clotrimazole	Clotrimazole inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]	12235267
D003022	Clotrimazole	Clotrimazole results in increased expression of ABCB1 protein	8632764
D045783	Clove Oil	Clove Oil results in increased expression of ABCB1 mRNA	30071242
D003024	Clozapine	Clozapine results in decreased activity of ABCB1 protein	16810505
D003024	Clozapine	Clozapine inhibits the reaction [Bromocriptine results in increased expression of ABCB1 protein]	9111066
D003024	Clozapine	Clozapine inhibits the reaction [N-n-propylnorapomorphine results in increased expression of ABCB1 protein]	9111066
D003024	Clozapine	Clozapine inhibits the reaction [Quinpirole results in increased expression of ABCB1 protein]	9111066
C502467	cnidiadin	cnidiadin inhibits the reaction [ABCB1 protein results in increased export of Vinblastine]	15824923
C502467	cnidiadin	cnidiadin results in decreased activity of ABCB1 protein	15824923
C502467	cnidiadin	[cnidiadin results in decreased activity of ABCB1 protein] which results in increased susceptibility to Vinca Alkaloids	15824923
D003035	Cobalt	Cobalt results in increased activity of ABCB1 protein	2900677
D003035	Cobalt	[Cobalt results in increased activity of ABCB1 protein] which results in increased hydrolysis of Adenosine Triphosphate	2900677
C018021	cobaltous chloride	cobaltous chloride promotes the reaction [HIF1A protein results in increased expression of ABCB1 mRNA]	19128456
C018021	cobaltous chloride	HIPK2 protein inhibits the reaction [cobaltous chloride promotes the reaction [HIF1A protein results in increased expression of ABCB1 mRNA]]	19128456
C018021	cobaltous chloride	zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ABCB1 mRNA]	19714248
D003078	Colchicine	Sesquiterpenes analog inhibits the reaction [ABCB1 protein affects the transport of Colchicine]	15466210
D003078	Colchicine	ABCB1 protein affects the transport of Colchicine	16007523
D003078	Colchicine	ABCB1 protein results in decreased susceptibility to Colchicine	15112361; 15725475; 7905786;
D003078	Colchicine	ABCB1 protein results in increased export of Colchicine	15112361
D003078	Colchicine	Colchicine inhibits the reaction [Verapamil analog results in increased activity of ABCB1 protein mutant form]	12711602
D003078	Colchicine	Colchicine results in increased expression of ABCB1	24759273
D003078	Colchicine	Colchicine results in increased expression of ABCB1 mRNA	15342794
D003078	Colchicine	[MGMT protein co-treated with ABCB1 protein] results in decreased susceptibility to Colchicine	11792417
D003078	Colchicine	ABCB1 results in decreased susceptibility to Colchicine	20557448
D005576	Colforsin	Colforsin results in increased expression of ABCB1 mRNA	23164983
D005576	Colforsin	[Rifampin co-treated with Colforsin] results in increased expression of ABCB1 protein	23164983
D005576	Colforsin	Colforsin results in increased expression of ABCB1 mRNA	12926078
D005576	Colforsin	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased expression of ABCB1 mRNA]	12926078
D003300	Copper	Copper results in increased expression of ABCB1 protein	15084411
D003300	Copper	Copper inhibits the reaction [Magnesium results in increased activity of ABCB1 protein]	2900677
D003300	Copper	Copper results in increased expression of ABCB1 mRNA	19501419
C021984	corexit 9527	corexit 9527 results in increased expression of ABCB1 mRNA	19501419
C000614311	coriander oil	coriander oil results in increased expression of ABCB1 mRNA	30071242
D000077547	Crizotinib	Crizotinib inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	22233293
D000077547	Crizotinib	Crizotinib inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	22233293
D000077547	Crizotinib	Crizotinib promotes the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]	22233293
D000077547	Crizotinib	Crizotinib results in decreased activity of ABCB1 protein	28369651
C038106	cucurbitacin I	cucurbitacin I inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D003474	Curcumin	ABCB1 affects the susceptibility to Curcumin	15476675
D003474	Curcumin	ABCB1 protein results in decreased susceptibility to Curcumin	27318188
D003474	Curcumin	Curcumin analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	26689174
D003474	Curcumin	Curcumin analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vinblastine]	26689174
D003474	Curcumin	Curcumin analog results in decreased expression of ABCB1 protein	26689174
D003474	Curcumin	Curcumin inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	26689174
D003474	Curcumin	Curcumin inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vinblastine]	26689174
D003474	Curcumin	Curcumin inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	18385293
D003474	Curcumin	Curcumin results in decreased expression of ABCB1 mRNA	17121181; 18414057; 18439772;
D003474	Curcumin	Curcumin results in decreased expression of and results in decreased activity of ABCB1 protein	18439772
D003474	Curcumin	[sulfinosine co-treated with Curcumin] results in decreased expression of ABCB1 mRNA	18414057
D003474	Curcumin	Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of ABCB1 mRNA]	18200517
D003513	Cycloheximide	Cycloheximide promotes the reaction [Reserpine results in increased expression of ABCB1 mRNA]	7476894
D003513	Cycloheximide	Cycloheximide results in increased expression of ABCB1 mRNA	7476894
D003513	Cycloheximide	Cycloheximide inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D003513	Cycloheximide	Cycloheximide inhibits the reaction [[Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]	18474546
D003513	Cycloheximide	Cycloheximide inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D003513	Cycloheximide	Cycloheximide inhibits the reaction [[Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]	18474546
D003520	Cyclophosphamide	ABCB1 protein affects the susceptibility to [Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil]	12576456
D003520	Cyclophosphamide	ABCB1 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide]	12576456
D003520	Cyclophosphamide	[Cyclophosphamide results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA	20041327
D003520	Cyclophosphamide	Cyclophosphamide results in increased expression of ABCB1 protein	20041327
D003520	Cyclophosphamide	NR1I2 protein promotes the reaction [Cyclophosphamide results in increased expression of ABCB1 protein]	20041327
D003520	Cyclophosphamide	Cyclophosphamide results in decreased expression of ABCB1 mRNA	20623750
D016572	Cyclosporine	[Cyclosporine results in decreased activity of ABCB1 protein] inhibits the reaction [avermectin results in increased abundance of Calcium]	23523950
D016572	Cyclosporine	ABCB1 protein affects the export of Cyclosporine	15964336
D016572	Cyclosporine	ABCB1 protein affects the susceptibility to Cyclosporine	12387747; 28623111;
D016572	Cyclosporine	ABCB1 protein affects the transport of Cyclosporine	15964407
D016572	Cyclosporine	ABCB1 protein polymorphism affects the susceptibility to Cyclosporine	15772250
D016572	Cyclosporine	ABCB1 protein results in increased transport of Cyclosporine	17045309
D016572	Cyclosporine	Cyclosporine affects the expression of ABCB1 mRNA	20106945
D016572	Cyclosporine	Cyclosporine binds to and results in decreased activity of ABCB1 protein	23976943
D016572	Cyclosporine	[Cyclosporine binds to and results in decreased activity of ABCB1 protein] which results in decreased export of Digoxin	23976943
D016572	Cyclosporine	[Cyclosporine co-treated with Raloxifene Hydrochloride] results in decreased expression of ABCB1 mRNA	17096884
D016572	Cyclosporine	[Cyclosporine co-treated with Raloxifene Hydrochloride] results in decreased expression of ABCB1 protein	17096884
D016572	Cyclosporine	Cyclosporine inhibits the reaction [ABCB1 protein affects the export of calcein AM]	10617675
D016572	Cyclosporine	Cyclosporine inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	17947497; 7905786;
D016572	Cyclosporine	Cyclosporine inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]	7905786
D016572	Cyclosporine	Cyclosporine inhibits the reaction [ABCB1 protein results in decreased uptake of Doxorubicin]	17947497
D016572	Cyclosporine	Cyclosporine inhibits the reaction [ABCB1 protein results in increased chemical synthesis of globotriaosylceramide]	14662772
D016572	Cyclosporine	Cyclosporine inhibits the reaction [ABCB1 protein results in increased chemical synthesis of Glucosylceramides]	14662772
D016572	Cyclosporine	Cyclosporine inhibits the reaction [ABCB1 protein results in increased chemical synthesis of Lactosylceramides]	14662772
D016572	Cyclosporine	Cyclosporine inhibits the reaction [ABCB1 protein results in increased export of Daunorubicin]	12526924
D016572	Cyclosporine	Cyclosporine inhibits the reaction [ABCB1 protein results in increased export of Diazinon]	16221533
D016572	Cyclosporine	Cyclosporine inhibits the reaction [ABCB1 protein results in increased export of Fluorescent Dyes]	27450509
D016572	Cyclosporine	Cyclosporine inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]	12235267
D016572	Cyclosporine	Cyclosporine inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]	12235267
D016572	Cyclosporine	Cyclosporine inhibits the reaction [Verapamil analog results in increased activity of ABCB1 protein mutant form]	12711602
D016572	Cyclosporine	Cyclosporine results in decreased activity of ABCB1 protein	12387747; 16316932; 18408562;
D016572	Cyclosporine	Cyclosporine results in decreased activity of ABCB1 protein mutant form	12711602
D016572	Cyclosporine	[Cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylaconine	23200901
D016572	Cyclosporine	[Cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylhypaconine	23200901
D016572	Cyclosporine	[Cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylmesaconine	23200901
D016572	Cyclosporine	[Cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of hypaconitine	23200901
D016572	Cyclosporine	[Cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of mesaconitine	23200901
D016572	Cyclosporine	[Cyclosporine results in decreased activity of ABCB1 protein] which results in increased susceptibility to Paclitaxel	18673531
D016572	Cyclosporine	Cyclosporine results in decreased expression of ABCB1 mRNA	17096884; 24973091; 27989131;
D016572	Cyclosporine	Cyclosporine results in decreased expression of ABCB1 protein	17096884
D016572	Cyclosporine	Cyclosporine results in increased expression of ABCB1 mRNA	12387747; 25562108;
D016572	Cyclosporine	Plant Extracts affects the reaction [ABCB1 protein results in increased transport of Cyclosporine]	12545142
D016572	Cyclosporine	Cyclosporine inhibits the reaction [ABCB1 results in decreased uptake of Digoxin]	20557448
D016572	Cyclosporine	Cyclosporine inhibits the reaction [ABCB1 results in decreased susceptibility to Cadmium Chloride]	10636889
D016572	Cyclosporine	Cyclosporine results in decreased activity of ABCB1 protein	17609666
D016572	Cyclosporine	[Cyclosporine results in decreased activity of ABCB1 protein] which results in increased uptake of Carvedilol	17609666
D016572	Cyclosporine	[Thioacetamide co-treated with Cyclosporine] results in increased expression of ABCB1 mRNA	15770714
D016572	Cyclosporine	Cyclosporine affects the folding of and affects the localization of ABCB1 protein mutant form	15530432
D016572	Cyclosporine	Cyclosporine affects the localization of ABCB1 protein mutant form	22184139
D016572	Cyclosporine	Cyclosporine affects the metabolism of and affects the folding of ABCB1 protein mutant form	22184139
D016572	Cyclosporine	Cyclosporine binds to ABCB1 protein	7808368
D016572	Cyclosporine	Cyclosporine inhibits the reaction [ABCB1 protein results in increased export of retrorsine]	24799337
D016572	Cyclosporine	Cyclosporine results in decreased activity of ABCB1 protein	15744065; 23200901; 23523950; 23562926;
D016572	Cyclosporine	Cyclosporine results in increased activity of ABCB1 protein mutant form	22184139
D003524	Cyclosporins	Cyclosporins affects the activity of ABCB1 protein	15788683
D003529	Cymarine	Cymarine inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	23104431
C017160	cypermethrin	cypermethrin results in increased activity of ABCB1 protein	17490606
C017160	cypermethrin	tetramethylrosamine inhibits the reaction [ABCB1 protein results in increased transport of cypermethrin]	17490606
D003561	Cytarabine	ABCB1 protein affects the susceptibility to Cytarabine	17852453
D003561	Cytarabine	Cytarabine results in increased expression of ABCB1	11573427
D003609	Dactinomycin	ABCB1 protein results in decreased susceptibility to Dactinomycin	15725475
D003609	Dactinomycin	Dactinomycin inhibits the reaction [Estradiol results in increased expression of ABCB1 mRNA]	19813763
D003609	Dactinomycin	Dactinomycin inhibits the reaction [Estradiol results in increased expression of ABCB1 protein]	19813763
D003609	Dactinomycin	Dactinomycin inhibits the reaction [Progesterone results in increased expression of ABCB1 mRNA]	19813763
D003609	Dactinomycin	Dactinomycin inhibits the reaction [Progesterone results in increased expression of ABCB1 protein]	19813763
D003609	Dactinomycin	Dactinomycin inhibits the reaction [sodium arsenite results in increased expression of ABCB1 mRNA]	1967174
D003609	Dactinomycin	ABCB1 protein results in decreased susceptibility to Dactinomycin	11455017
D003609	Dactinomycin	Dactinomycin inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D003609	Dactinomycin	Dactinomycin inhibits the reaction [[Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]	18474546
D003609	Dactinomycin	Dactinomycin inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D003609	Dactinomycin	Dactinomycin inhibits the reaction [[Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]	18474546
D003630	Daunorubicin	[5-Methoxypsoralen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of Daunorubicin	29079042
D003630	Daunorubicin	ABCB1 affects the susceptibility to Daunorubicin	12174371
D003630	Daunorubicin	ABCB1 mutant form promotes the reaction [Daunorubicin results in decreased expression of ABCB1 mRNA]	20957165; 20957165;
D003630	Daunorubicin	ABCB1 mutant form promotes the reaction [Daunorubicin results in decreased expression of ABCB1 protein]	20957165; 20957165;
D003630	Daunorubicin	ABCB1 mutant form promotes the reaction [Magnetite Nanoparticles results in increased susceptibility to Daunorubicin]	20957165
D003630	Daunorubicin	ABCB1 mutant form results in increased susceptibility to Daunorubicin	20957165
D003630	Daunorubicin	ABCB1 protein affects the susceptibility to Daunorubicin	24954033
D003630	Daunorubicin	ABCB1 protein results in decreased uptake of Daunorubicin	10617675
D003630	Daunorubicin	ABCB1 protein results in increased export of Daunorubicin	12526924; 9815696;
D003630	Daunorubicin	ABCB1 protein results in increased import of Daunorubicin	18955043
D003630	Daunorubicin	ABCB1 protein results in increased transport of Daunorubicin	11231118; 12708479;
D003630	Daunorubicin	Amiodarone inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]	11231118
D003630	Daunorubicin	aurapten promotes the reaction [ABCB1 protein results in increased import of Daunorubicin]	18955043
D003630	Daunorubicin	azelastine inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]	11231118
D003630	Daunorubicin	Carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]	12708479
D003630	Daunorubicin	[Carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]] which results in decreased susceptibility to Daunorubicin	12708479
D003630	Daunorubicin	Cyclosporine inhibits the reaction [ABCB1 protein results in increased export of Daunorubicin]	12526924
D003630	Daunorubicin	[Daunorubicin co-treated with bromotetrandrine co-treated with Magnetite Nanoparticles] results in decreased expression of ABCB1 mRNA	22114476
D003630	Daunorubicin	[Daunorubicin co-treated with bromotetrandrine] results in decreased expression of ABCB1 mRNA	22114476
D003630	Daunorubicin	Daunorubicin promotes the reaction [ABCB1 mutant form results in decreased expression of ABCB1 protein]	20957165; 20957165;
D003630	Daunorubicin	Daunorubicin promotes the reaction [Magnetite Nanoparticles results in decreased expression of ABCB1 protein]	20957165
D003630	Daunorubicin	Daunorubicin results in decreased expression of ABCB1 mRNA	20957165
D003630	Daunorubicin	Daunorubicin results in decreased expression of ABCB1 protein	20957165
D003630	Daunorubicin	desethylamiodarone inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]	11231118
D003630	Daunorubicin	desmethylazelastine inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]	11231118
D003630	Daunorubicin	Magnetite Nanoparticles promotes the reaction [ABCB1 mutant form promotes the reaction [Daunorubicin results in decreased expression of ABCB1 mRNA]]	20957165; 20957165;
D003630	Daunorubicin	Magnetite Nanoparticles promotes the reaction [ABCB1 mutant form promotes the reaction [Daunorubicin results in decreased expression of ABCB1 protein]]	20957165; 20957165;
D003630	Daunorubicin	Magnetite Nanoparticles promotes the reaction [ABCB1 mutant form results in increased susceptibility to Daunorubicin]	20957165
D003630	Daunorubicin	Magnetite Nanoparticles promotes the reaction [Daunorubicin promotes the reaction [ABCB1 mutant form results in decreased expression of ABCB1 protein]]	20957165; 20957165;
D003630	Daunorubicin	Magnetite Nanoparticles promotes the reaction [Daunorubicin results in decreased expression of ABCB1 mRNA]	20957165
D003630	Daunorubicin	Magnetite Nanoparticles promotes the reaction [Daunorubicin results in decreased expression of ABCB1 protein]	20957165
D003630	Daunorubicin	[Methoxsalen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of Daunorubicin	29079042
D003630	Daunorubicin	Mitotane inhibits the reaction [ABCB1 protein results in increased export of Daunorubicin]	9815696
D003630	Daunorubicin	nobiletin promotes the reaction [ABCB1 protein results in increased import of Daunorubicin]	18955043
D003630	Daunorubicin	Sesquiterpenes analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Daunorubicin]	15466210
D003630	Daunorubicin	[Sodium Azide co-treated with Iodoacetates] inhibits the reaction [ABCB1 protein results in increased export of Daunorubicin]	12526924
D003630	Daunorubicin	valspodar inhibits the reaction [ABCB1 protein results in increased export of Daunorubicin]	9815696
D003630	Daunorubicin	Verapamil inhibits the reaction [[5-Methoxypsoralen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of Daunorubicin]	29079042
D003630	Daunorubicin	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]	12708479
D003630	Daunorubicin	Verapamil inhibits the reaction [[Methoxsalen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of Daunorubicin]	29079042
D003630	Daunorubicin	ABCB1 results in decreased susceptibility to Daunorubicin	20557448
D003630	Daunorubicin	ABCB1 protein affects the transport of Daunorubicin	12642476
D003630	Daunorubicin	Daunorubicin inhibits the reaction [ABCB1 results in increased transport of estradiol-17 beta-glucuronide]	9794924
D003630	Daunorubicin	ABCB1 results in decreased susceptibility to Daunorubicin	18310528
D003630	Daunorubicin	Mometasone Furoate inhibits the reaction [ABCB1 results in decreased susceptibility to Daunorubicin]	18310528
D003634	DDT	DDT metabolite results in decreased activity of ABCB1 protein	23169446
D003634	DDT	DDT results in increased expression of ABCB1 mRNA	15710169; 24464585;
D003634	DDT	DDT results in increased expression of ABCB1 mRNA	29477483
D000077209	Decitabine	[Decitabine affects the methylation of ABCB1 gene] which affects the expression of ABCB1 mRNA	18673531; 18673531;
D000077209	Decitabine	[[Decitabine co-treated with trichostatin A] affects the methylation of ABCB1 gene] which affects the expression of ABCB1 mRNA	18673531; 18673531;
D000077209	Decitabine	Decitabine promotes the reaction [trichostatin A results in increased expression of ABCB1 mRNA]	27570640
D000077209	Decitabine	Decitabine results in increased expression of ABCB1 mRNA	27570640
C478098	dehydroandrographolide	dehydroandrographolide inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	24380838
D003703	Demecolcine	Demecolcine inhibits the reaction [Verapamil analog results in increased activity of ABCB1 protein mutant form]	12711602
D003703	Demecolcine	Demecolcine results in increased activity of ABCB1 protein mutant form	12711602
D003840	Deoxycholic Acid	Deoxycholic Acid metabolite results in increased expression of ABCB1 mRNA	27871908
D003847	Deoxyglucose	Deoxyglucose inhibits the reaction [ABCB1 protein results in increased export of Diazinon]	16221533
C007262	deoxynivalenol	ABCB1 protein results in decreased susceptibility to deoxynivalenol	29174985
C007262	deoxynivalenol	deoxynivalenol inhibits the reaction [valspodar inhibits the reaction [ABCB1 protein results in increased export of calcein AM]]	29174985
C036116	desethylamiodarone	desethylamiodarone inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]	11231118
C036116	desethylamiodarone	desethylamiodarone inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11231118
C036116	desethylamiodarone	desethylamiodarone results in decreased activity of ABCB1 protein	11231118
C494355	desisobutyrylciclesonide	desisobutyrylciclesonide inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	16442095
C494355	desisobutyrylciclesonide	desisobutyrylciclesonide inhibits the reaction [ABCB1 protein results in increased export of fluorexon]	16442095
C121345	desloratadine	ABCB1 protein results in increased export of desloratadine	12584158
C054114	desmethylazelastine	desmethylazelastine inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]	11231118
C054114	desmethylazelastine	desmethylazelastine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11231118
C054114	desmethylazelastine	desmethylazelastine results in decreased activity of ABCB1 protein	11231118
D003907	Dexamethasone	ABCB1 gene polymorphism affects the reaction [Dexamethasone results in decreased secretion of IFNG protein]	16321374
D003907	Dexamethasone	ABCB1 gene polymorphism affects the reaction [Dexamethasone results in decreased secretion of IL2 protein]	16321374
D003907	Dexamethasone	ABCB1 gene polymorphism affects the reaction [Dexamethasone results in decreased secretion of IL4 protein]	16321374
D003907	Dexamethasone	ABCB1 gene polymorphism affects the reaction [Dexamethasone results in decreased secretion of TNF protein]	16321374
D003907	Dexamethasone	ABCB1 gene polymorphism affects the susceptibility to Dexamethasone	16321374
D003907	Dexamethasone	ABCB1 protein results in increased secretion of Dexamethasone	22464980
D003907	Dexamethasone	Dexamethasone results in decreased activity of ABCB1 protein	12387747
D003907	Dexamethasone	Dexamethasone results in increased expression of ABCB1 mRNA	12387747
D003907	Dexamethasone	Elacridar inhibits the reaction [ABCB1 protein results in increased secretion of Dexamethasone]	22464980
D003907	Dexamethasone	[Tacrolimus results in decreased activity of ABCB1 protein] which results in decreased export of Dexamethasone	20080907
D003907	Dexamethasone	valspodar inhibits the reaction [ABCB1 protein results in increased secretion of Dexamethasone]	22464980
D003907	Dexamethasone	Dexamethasone results in increased expression of ABCB1 mRNA	16303967
D003907	Dexamethasone	Dexamethasone results in decreased expression of ABCB1 mRNA	20607812
D003907	Dexamethasone	Dexamethasone results in increased expression of ABCB1 protein	17015168
C025527	diacetolol	diacetolol binds to ABCB1 protein	10783826
C100261	diacetyldiphenylurea bisguanylhydrazone	diacetyldiphenylurea bisguanylhydrazone inhibits the reaction [5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one results in decreased expression of ABCB1 mRNA]	23470866
C028009	diallyl disulfide	diallyl disulfide results in increased expression of ABCB1 mRNA	22397993
C042577	diallyl trisulfide	diallyl trisulfide results in decreased expression of ABCB1 protein	24788927
C042577	diallyl trisulfide	diallyl trisulfide results in increased expression of ABCB1 mRNA	22397993
D003976	Diazinon	ABCB1 protein results in decreased susceptibility to Diazinon	21127835
D003976	Diazinon	ABCB1 protein results in increased export of Diazinon	16221533
D003976	Diazinon	Cyclosporine inhibits the reaction [ABCB1 protein results in increased export of Diazinon]	16221533
D003976	Diazinon	Deoxyglucose inhibits the reaction [ABCB1 protein results in increased export of Diazinon]	16221533
D003976	Diazinon	Diazinon affects the reaction [ABCB1 protein results in increased transport of Digoxin]	16221533
D003976	Diazinon	Diazinon affects the reaction [ABCB1 protein results in increased transport of Vinblastine]	16221533
D003976	Diazinon	Diazinon inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
D003976	Diazinon	Diazinon promotes the reaction [Endosulfan inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
D003976	Diazinon	Diazinon promotes the reaction [Endosulfan results in decreased activity of ABCB1 protein]	21783720
D003976	Diazinon	Diazinon promotes the reaction [phosalone inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
D003976	Diazinon	Diazinon promotes the reaction [phosalone results in decreased activity of ABCB1 protein]	21783720
D003976	Diazinon	Diazinon promotes the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
D003976	Diazinon	Diazinon promotes the reaction [propiconazole results in decreased activity of ABCB1 protein]	21783720
D003976	Diazinon	Diazinon promotes the reaction [Verapamil inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
D003976	Diazinon	Diazinon promotes the reaction [Verapamil results in decreased activity of ABCB1 protein]	21783720
D003976	Diazinon	Diazinon results in decreased activity of ABCB1 protein	21783720
D003976	Diazinon	Diazinon results in increased activity of ABCB1 protein	16221533
D003976	Diazinon	Diazinon results in increased expression of ABCB1 protein	16221533; 21127835;
D003976	Diazinon	Sodium Azide inhibits the reaction [ABCB1 protein results in increased export of Diazinon]	16221533
D003976	Diazinon	valspodar inhibits the reaction [ABCB1 protein results in increased export of Diazinon]	16221533
D003976	Diazinon	Diazinon results in increased expression of ABCB1 mRNA	16221533
D003976	Diazinon	Diazinon results in increased expression of ABCB1 protein	16221533
C041517	dibenzo(a,l)pyrene	dibenzo(a,l)pyrene results in increased expression of ABCB1 mRNA	15566942
D003633	Dichlorodiphenyl Dichloroethylene	Dichlorodiphenyl Dichloroethylene results in decreased expression of ABCB1 mRNA	15710169
D003633	Dichlorodiphenyl Dichloroethylene	Dichlorodiphenyl Dichloroethylene results in increased expression of ABCB1 mRNA	15710169
D004004	Dichlororibofuranosylbenzimidazole	Dichlororibofuranosylbenzimidazole inhibits the reaction [mangiferin results in increased expression of ABCB1 protein]	20513373
D004004	Dichlororibofuranosylbenzimidazole	Dichlororibofuranosylbenzimidazole inhibits the reaction [sodium arsenite results in increased expression of ABCB1 protein]	16121039
C000944	dicrotophos	dicrotophos results in decreased expression of ABCB1 mRNA	28302478
D004026	Dieldrin	Dieldrin results in increased expression of ABCB1 mRNA	24464585
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate promotes the reaction [NR1I2 protein results in increased expression of ABCB1 mRNA]	17003290
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in increased expression of ABCB1 mRNA	17003290
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with Cisplatin] results in increased expression of ABCB1 protein	11818250
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with Epirubicin] results in increased expression of ABCB1 protein	11818250
D004052	Diethylnitrosamine	Diethylnitrosamine results in increased expression of ABCB1 protein	11818250
D004054	Diethylstilbestrol	Diethylstilbestrol results in decreased expression of ABCB1 protein	16925584
D004074	Digitoxin	ABCB1 protein results in increased transport of Digitoxin	26708294
D004074	Digitoxin	Digitoxin inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	23104431
D004076	Digoxigenin	ABCB1 protein results in increased transport of Digoxigenin	26708294
D004077	Digoxin	[TNF protein results in increased expression of ABCB1 protein] which results in increased export of Digoxin	21104926
D004077	Digoxin	ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of ALB mRNA]	25419811
D004077	Digoxin	ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of DAO mRNA]	25419811
D004077	Digoxin	ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of EBF3 mRNA]	25419811
D004077	Digoxin	ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of GABRQ mRNA]	25419811
D004077	Digoxin	ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of GLRA1 mRNA]	25419811
D004077	Digoxin	ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of KLK6 mRNA]	25419811
D004077	Digoxin	ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of MAB21L2 mRNA]	25419811
D004077	Digoxin	ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of SLC10A4 mRNA]	25419811
D004077	Digoxin	ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of SLC18A2 mRNA]	25419811
D004077	Digoxin	ABCB1 gene mutant form affects the reaction [Digoxin affects the expression of TTR mRNA]	25419811
D004077	Digoxin	ABCB1 gene mutant form results in increased susceptibility to Digoxin	25419811
D004077	Digoxin	ABCB1 mutant form results in increased susceptibility to Digoxin	16594604; 23186803;
D004077	Digoxin	[ML 7 results in decreased activity of MYLK protein] affects the reaction [ABCB1 protein affects the transport of Digoxin]	20510202
D004077	Digoxin	MYL9 protein modified form affects the reaction [ABCB1 protein affects the transport of Digoxin analog]	20510202
D004077	Digoxin	[Verapamil results in decreased activity of ABCB1 protein] which affects the transport of Digoxin	20510202
D004077	Digoxin	18alpha-glycyrrhetinic acid inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	24380838
D004077	Digoxin	2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [Digoxin results in increased expression of ABCB1 protein]	19647009
D004077	Digoxin	3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Digoxin results in increased expression of ABCB1 mRNA]	19647009
D004077	Digoxin	3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Digoxin results in increased expression of ABCB1 protein]	19647009
D004077	Digoxin	ABCB1 gene SNP affects the abundance of Digoxin	21311904
D004077	Digoxin	ABCB1 gene SNP affects the transport of Digoxin	17365992
D004077	Digoxin	ABCB1 protein affects the transport of Digoxin	15969931; 19505989;
D004077	Digoxin	ABCB1 protein binds to and affects the metabolism of Digoxin	15856409
D004077	Digoxin	ABCB1 protein results in decreased uptake of Digoxin	10617675
D004077	Digoxin	ABCB1 protein results in increased export of Digoxin	16674925; 26888941;
D004077	Digoxin	ABCB1 protein results in increased transport of Digoxin	10527640; 11231118; 11895100; 16221533; 16671962; 17365992; 18385293; 23976943; 24380838;
D004077	Digoxin	ABCB1 protein results in increased uptake of Digoxin	16904803
D004077	Digoxin	abietic acid inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D004077	Digoxin	Amiodarone inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11231118
D004077	Digoxin	azelastine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11231118
D004077	Digoxin	benidipine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
D004077	Digoxin	Bepridil inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
D004077	Digoxin	beta-pinene inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D004077	Digoxin	Bisoprolol inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	16671962
D004077	Digoxin	Capsaicin affects the reaction [ABCB1 protein results in increased export of Digoxin]	16674925
D004077	Digoxin	Carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100; 16671962;
D004077	Digoxin	citronellal inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D004077	Digoxin	[citronellal results in decreased activity of ABCB1 protein] which results in decreased export of Digoxin	15890377
D004077	Digoxin	citronellol inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D004077	Digoxin	[citronellol results in decreased activity of ABCB1 protein] which results in decreased export of Digoxin	15890377
D004077	Digoxin	cucurbitacin I inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D004077	Digoxin	Curcumin inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	18385293
D004077	Digoxin	[Cyclosporine binds to and results in decreased activity of ABCB1 protein] which results in decreased export of Digoxin	23976943
D004077	Digoxin	dehydroandrographolide inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	24380838
D004077	Digoxin	desethylamiodarone inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11231118
D004077	Digoxin	desmethylazelastine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11231118
D004077	Digoxin	Diazinon affects the reaction [ABCB1 protein results in increased transport of Digoxin]	16221533
D004077	Digoxin	Digoxin binds to ABCB1 protein	23976943
D004077	Digoxin	Digoxin inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	23104431
D004077	Digoxin	Digoxin results in increased expression of ABCB1 mRNA	19647009
D004077	Digoxin	Digoxin results in increased expression of ABCB1 protein	19647009
D004077	Digoxin	[Digoxin results in increased expression of ABCB1] which results in decreased susceptibility to Doxorubicin	19647009
D004077	Digoxin	Diltiazem inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
D004077	Digoxin	Doxazosin inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
D004077	Digoxin	efonidipine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
D004077	Digoxin	[Elacridar binds to and results in decreased activity of ABCB1 protein] which results in decreased export of Digoxin	23976943
D004077	Digoxin	[Elacridar results in decreased activity of ABCB1 protein] which results in increased uptake of Digoxin	25844889
D004077	Digoxin	Emodin inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	24380838
D004077	Digoxin	Fusidic Acid inhibits the reaction [ABCB1 protein results in increased export of Digoxin]	26888941
D004077	Digoxin	gamma-terpinene inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D004077	Digoxin	gingerol inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	18385293
D004077	Digoxin	ginsenoside F2 analog inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	24380838
D004077	Digoxin	Glycyrrhetinic Acid inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D004077	Digoxin	[isopropyl 5,12-hydroxypentadeca-8,10-dien-6,14-diynoate results in decreased activity of ABCB1 protein] which results in increased uptake of Digoxin	25844889
D004077	Digoxin	Itraconazole inhibits the reaction [ABCB1 protein affects the transport of Digoxin]	15969931
D004077	Digoxin	[Ketoconazole binds to and results in decreased activity of ABCB1 protein] which results in decreased export of Digoxin	23976943
D004077	Digoxin	Ketoconazole inhibits the reaction [ABCB1 protein affects the transport of Digoxin]	15969931
D004077	Digoxin	Ketoconazole inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	17365992
D004077	Digoxin	[Ketoconazole results in decreased activity of ABCB1 protein] which results in increased uptake of Digoxin	25844889
D004077	Digoxin	KN 93 inhibits the reaction [Digoxin results in increased expression of ABCB1 protein]	19647009
D004077	Digoxin	manidipine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
D004077	Digoxin	mepirodipine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
D004077	Digoxin	Nicardipine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
D004077	Digoxin	nilvadipine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
D004077	Digoxin	Nisoldipine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
D004077	Digoxin	ophiobolin A inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D004077	Digoxin	[Plant Extracts results in decreased activity of ABCB1 protein] which results in decreased export of Digoxin	15890377
D004077	Digoxin	Propranolol inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	16671962
D004077	Digoxin	rhodioloside affects the reaction [ABCB1 protein results in increased transport of Digoxin]	24380838
D004077	Digoxin	Rifampin promotes the reaction [ABCB1 protein results in increased transport of Digoxin]	17365992
D004077	Digoxin	terpinolene inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D004077	Digoxin	valspodar inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	16671962
D004077	Digoxin	[valspodar results in decreased activity of ABCB1 protein] which results in decreased transport of Digoxin	10997946
D004077	Digoxin	[Verapamil binds to and results in decreased activity of ABCB1 protein] which results in decreased export of Digoxin	23976943
D004077	Digoxin	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	10527640; 11895100; 24380838;
D004077	Digoxin	Verapamil inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D004077	Digoxin	[Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of Digoxin	10997946
D004077	Digoxin	ABCB1 results in decreased uptake of Digoxin	20557448
D004077	Digoxin	Cyclosporine inhibits the reaction [ABCB1 results in decreased uptake of Digoxin]	20557448
D004077	Digoxin	Verapamil inhibits the reaction [ABCB1 results in decreased uptake of Digoxin]	20557448
D004077	Digoxin	ABCB1 protein affects the secretion of Digoxin	21240898; 21341280;
D004077	Digoxin	ABCB1 protein results in increased transport of Digoxin	15276087
D004077	Digoxin	Acetaminophen promotes the reaction [ABCB1 protein results in increased transport of Digoxin]	15276087
D004077	Digoxin	ABCB1 protein affects the metabolism of Digoxin	23104431
D004110	Diltiazem	Diltiazem inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
C007220	dimethyl 2,3,5,6-tetrachloroterephthalate	dimethyl 2,3,5,6-tetrachloroterephthalate results in increased expression of ABCB1 mRNA	22819804
C510843	dimethyl-4,4'-dimethoxy-5,6,5',6'-dimethylene dioxybiphenyl-2,2'-dicarboxylate	dimethyl-4,4'-dimethoxy-5,6,5',6'-dimethylene dioxybiphenyl-2,2'-dicarboxylate results in decreased expression of ABCB1 protein	16937080
D004128	Dimethylnitrosamine	Dimethylnitrosamine results in increased expression of ABCB1 mRNA	17072980
D004121	Dimethyl Sulfoxide	Dimethyl Sulfoxide affects the expression of ABCB1 mRNA	12843640
C019357	dioscin	dioscin results in decreased expression of ABCB1 mRNA	24680847
C019357	dioscin	dioscin results in decreased expression of ABCB1 protein	24680847
C019357	dioscin	dioscin results in decreased expression of ABCB1	24680847
C007517	diphenyleneiodonium	diphenyleneiodonium inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]	18474546
C007517	diphenyleneiodonium	diphenyleneiodonium inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D004221	Disulfiram	Disulfiram affects the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]	14978246
D004221	Disulfiram	Disulfiram inhibits the reaction [8-azidoadenosine 5'-triphosphate binds to ABCB1 protein]	14978246
D004221	Disulfiram	Disulfiram inhibits the reaction [azidopine binds to ABCB1 protein]	14978246
D004221	Disulfiram	Disulfiram inhibits the reaction [azidoprazosin binds to ABCB1 protein]	14978246
D004221	Disulfiram	Disulfiram metabolite results in decreased activity of ABCB1 protein	16028354
D004221	Disulfiram	Disulfiram results in decreased activity of ABCB1 protein	10841824; 14978246;
D000077143	Docetaxel	ABCB1 gene polymorphism affects the susceptibility to Docetaxel	25648089
D000077143	Docetaxel	ABCB1 mRNA results in increased susceptibility to Docetaxel	15239142
D000077143	Docetaxel	ABCB1 protein affects the reaction [EGFR protein results in decreased susceptibility to Docetaxel]	24888374
D000077143	Docetaxel	ABCB1 protein results in decreased susceptibility to Docetaxel	17284363; 20196146;
D000077143	Docetaxel	cinchonine analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Docetaxel]	20196146
D000077143	Docetaxel	cinchonine inhibits the reaction [ABCB1 protein results in decreased susceptibility to Docetaxel]	20196146
D000077143	Docetaxel	Docetaxel analog binds to ABCB1 protein	29625142
D000077143	Docetaxel	Docetaxel binds to ABCB1 protein	29625142
D000077143	Docetaxel	Docetaxel results in decreased expression of ABCB1 mRNA	22445862
D000077143	Docetaxel	[Docetaxel results in decreased susceptibility to Docetaxel] which results in increased expression of ABCB1 mRNA	19944135
D000077143	Docetaxel	[Docetaxel results in decreased susceptibility to Docetaxel] which results in increased expression of ABCB1 protein	19944135
D000077143	Docetaxel	[Docetaxel results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA	20041327
D000077143	Docetaxel	Docetaxel results in increased expression of ABCB1 mRNA	15239124
D000077143	Docetaxel	Docetaxel results in increased expression of ABCB1 protein	15239124; 20041327;
D000077143	Docetaxel	[Docetaxel results in increased expression of TP53 mRNA] which results in decreased expression of ABCB1 mRNA	22445862
D000077143	Docetaxel	NR1I2 protein promotes the reaction [Docetaxel results in increased expression of and results in increased activity of ABCB1 protein]	20041327
D000077143	Docetaxel	Quinidine inhibits the reaction [ABCB1 protein results in decreased susceptibility to Docetaxel]	20196146
D000077143	Docetaxel	TP53 protein affects the reaction [Docetaxel results in decreased expression of ABCB1 mRNA]	22445862
D004294	Domperidone	ABCB1 gene SNP affects the susceptibility to Domperidone	21063774
C084101	doramectin	ABCB1 gene mutant form affects the reaction [doramectin affects the expression of ALB mRNA]	25419811
C084101	doramectin	ABCB1 gene mutant form affects the reaction [doramectin affects the expression of DAO mRNA]	25419811
C084101	doramectin	ABCB1 gene mutant form affects the reaction [doramectin affects the expression of EBF3 mRNA]	25419811
C084101	doramectin	ABCB1 gene mutant form affects the reaction [doramectin affects the expression of GABRQ mRNA]	25419811
C084101	doramectin	ABCB1 gene mutant form affects the reaction [doramectin affects the expression of GLRA1 mRNA]	25419811
C084101	doramectin	ABCB1 gene mutant form affects the reaction [doramectin affects the expression of KLK6 mRNA]	25419811
C084101	doramectin	ABCB1 gene mutant form affects the reaction [doramectin affects the expression of MAB21L2 mRNA]	25419811
C084101	doramectin	ABCB1 gene mutant form affects the reaction [doramectin affects the expression of SLC10A4 mRNA]	25419811
C084101	doramectin	ABCB1 gene mutant form affects the reaction [doramectin affects the expression of SLC18A2 mRNA]	25419811
C084101	doramectin	ABCB1 gene mutant form affects the reaction [doramectin affects the expression of TTR mRNA]	25419811
C084101	doramectin	ABCB1 gene mutant form results in increased susceptibility to doramectin	22834856; 25419811;
C084101	doramectin	ABCB1 mutant form results in increased susceptibility to doramectin	23186803
C084101	doramectin	doramectin results in decreased expression of ABCB1 mRNA	20487225
C084101	doramectin	doramectin results in decreased expression of ABCB1 protein	20487225
C516138	dorsomorphin	dorsomorphin inhibits the reaction [rubimaillin results in decreased expression of ABCB1 mRNA]	23466342
D017292	Doxazosin	Doxazosin inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
D004316	Doxepin	ABCB1 protein results in increased export of Doxepin	14550684
D004317	Doxorubicin	[valspodar results in decreased activity of ABCB1 protein] promotes the reaction [Doxorubicin results in decreased secretion of Hydrocortisone]	10898547
D004317	Doxorubicin	ABCB1 protein affects the susceptibility to Doxorubicin	24975508
D004317	Doxorubicin	Doxorubicin results in increased expression of ABCB1 protein	28093773
D004317	Doxorubicin	valspodar inhibits the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]	24975508
D004317	Doxorubicin	valspodar inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	15492788
D004317	Doxorubicin	[2-(1-hydroxy-4-oxocyclohexa-2,5-dienyl)pyran-4-one results in increased susceptibility to Doxorubicin] which results in decreased expression of ABCB1 protein	28987325
D004317	Doxorubicin	5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]	20438634; 20438634;
D004317	Doxorubicin	ABCB1 affects the susceptibility to Doxorubicin	12174371
D004317	Doxorubicin	ABCB1 mRNA results in decreased susceptibility to Doxorubicin	15765123; 16044152; 16322897; 7865906;
D004317	Doxorubicin	ABCB1 mRNA results in increased susceptibility to Doxorubicin	15239142
D004317	Doxorubicin	ABCB1 promoter modified form results in decreased susceptibility to Doxorubicin	16356834
D004317	Doxorubicin	ABCB1 protein affects the reaction [Doxorubicin results in decreased susceptibility to Paraquat]	23220037
D004317	Doxorubicin	ABCB1 protein affects the susceptibility to Doxorubicin	17085340; 24998637; 25824409;
D004317	Doxorubicin	ABCB1 protein affects the transport of Doxorubicin	16499877
D004317	Doxorubicin	ABCB1 protein inhibits the reaction [germacrone results in increased susceptibility to Doxorubicin]	29655913
D004317	Doxorubicin	ABCB1 protein results in decreased abundance of Doxorubicin	15861398
D004317	Doxorubicin	ABCB1 protein results in decreased export of Doxorubicin	16936711
D004317	Doxorubicin	ABCB1 protein results in decreased secretion of Doxorubicin	15967469
D004317	Doxorubicin	ABCB1 protein results in decreased susceptibility to Doxorubicin	11313874; 11355955; 12646961; 15112361; 15695394; 15725475; 15765123; 15861398; 16442095; 16831368; 17284363; 17947497; 20438634; 21459122; 21657271; 21721528; 22233293; 24321342; 25058526; 26564229; 27664577; 7083125; 7865906; 7905786; 8917702;
D004317	Doxorubicin	[ABCB1 protein results in decreased susceptibility to Doxorubicin] affects the reaction [5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]]	20438634
D004317	Doxorubicin	[ABCB1 protein results in decreased susceptibility to Doxorubicin] affects the reaction [eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]]	20438634
D004317	Doxorubicin	[ABCB1 protein results in decreased susceptibility to Doxorubicin] inhibits the reaction [Quercetin results in increased cleavage of PARP1 protein]	20438634
D004317	Doxorubicin	[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]	20438634; 20438634;
D004317	Doxorubicin	ABCB1 protein results in decreased uptake of Doxorubicin	17526808; 17947497; 20041327;
D004317	Doxorubicin	ABCB1 protein results in increased export of and results in decreased susceptibility to Doxorubicin	18829547
D004317	Doxorubicin	ABCB1 protein results in increased export of Doxorubicin	15112361; 17483874; 25058526; 27816545; 8917702;
D004317	Doxorubicin	ABCB1 protein results in increased transport of and affects the susceptibility to Doxorubicin	18461970
D004317	Doxorubicin	ABCB1 protein results in increased transport of Doxorubicin	12708479
D004317	Doxorubicin	ABCB1 protein results in increased uptake of Doxorubicin	27318188
D004317	Doxorubicin	ABCB1 results in decreased susceptibility to Doxorubicin	19232821
D004317	Doxorubicin	abemaciclib inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	27816545
D004317	Doxorubicin	Acetaminophen promotes the reaction [ABCB1 protein results in decreased uptake of Doxorubicin]	17526808
D004317	Doxorubicin	Acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of CASP7 protein]	25824409
D004317	Doxorubicin	Acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of PARP1 protein]	25824409
D004317	Doxorubicin	Beclomethasone inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	16442095
D004317	Doxorubicin	Carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Doxorubicin]	12708479
D004317	Doxorubicin	[Carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Doxorubicin]] which results in decreased susceptibility to Doxorubicin	12708479
D004317	Doxorubicin	[Carvedilol results in decreased activity of ABCB1 protein] which results in increased susceptibility to Doxorubicin	10571255
D004317	Doxorubicin	CEP 33779 inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	25058526
D004317	Doxorubicin	CEP 33779 inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	25058526
D004317	Doxorubicin	Chlorpyrifos inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	8917702
D004317	Doxorubicin	CJX1, amlodipine derivative inhibits the reaction [ABCB1 protein results in decreased secretion of Doxorubicin]	15967469
D004317	Doxorubicin	Clotrimazole inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	8917702
D004317	Doxorubicin	Crizotinib inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	22233293
D004317	Doxorubicin	Cyclosporine inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	17947497; 7905786;
D004317	Doxorubicin	Cyclosporine inhibits the reaction [ABCB1 protein results in decreased uptake of Doxorubicin]	17947497
D004317	Doxorubicin	desisobutyrylciclesonide inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	16442095
D004317	Doxorubicin	[Digoxin results in increased expression of ABCB1] which results in decreased susceptibility to Doxorubicin	19647009
D004317	Doxorubicin	[Doxorubicin co-treated with IL6 protein] results in increased expression of ABCB1 protein	29341321
D004317	Doxorubicin	Doxorubicin results in decreased expression of ABCB1 protein	25339540
D004317	Doxorubicin	Doxorubicin results in increased activity of ABCB1 protein	15501994; 17526808;
D004317	Doxorubicin	Doxorubicin results in increased expression of ABCB1	15736412
D004317	Doxorubicin	Doxorubicin results in increased expression of ABCB1 mRNA	16544145; 16937080; 17852453; 18510171; 18560228; 21054339; 25687049; 29655913; 30031762;
D004317	Doxorubicin	Doxorubicin results in increased expression of ABCB1 protein	15501994; 16579640; 29655913;
D004317	Doxorubicin	[Doxorubicin results in increased expression of ABCB1 protein] which results in decreased susceptibility to Paraquat	23220037
D004317	Doxorubicin	Endosulfan inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	8917702
D004317	Doxorubicin	eriodictyol inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]	20438634; 20438634;
D004317	Doxorubicin	Flupenthixol analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	7905786
D004317	Doxorubicin	gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]	25824409
D004317	Doxorubicin	[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of CASP7 protein	25824409
D004317	Doxorubicin	[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of PARP1 protein	25824409
D004317	Doxorubicin	germacrone inhibits the reaction [Doxorubicin results in increased expression of ABCB1 mRNA]	29655913
D004317	Doxorubicin	germacrone inhibits the reaction [Doxorubicin results in increased expression of ABCB1 protein]	29655913
D004317	Doxorubicin	Haloperidol inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	15946544
D004317	Doxorubicin	HIF1A protein affects the reaction [[Doxorubicin co-treated with IL6 protein] results in increased expression of ABCB1 protein]	29341321
D004317	Doxorubicin	[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]	19047049
D004317	Doxorubicin	[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]	19047049
D004317	Doxorubicin	hydramethylnon inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	8917702
D004317	Doxorubicin	Ivermectin inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	8917702
D004317	Doxorubicin	kaempferol inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]	20438634; 20438634;
D004317	Doxorubicin	Lapatinib inhibits the reaction [ABCB1 protein results in increased export of and results in decreased susceptibility to Doxorubicin]	18829547
D004317	Doxorubicin	Meloxicam inhibits the reaction [Doxorubicin results in increased activity of ABCB1 protein]	15501994
D004317	Doxorubicin	Meloxicam inhibits the reaction [Doxorubicin results in increased expression of ABCB1 protein]	15501994
D004317	Doxorubicin	Metformin inhibits the reaction [Doxorubicin results in increased expression of ABCB1 mRNA]	21054339
D004317	Doxorubicin	Mometasone Furoate inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	16442095
D004317	Doxorubicin	N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	24321342
D004317	Doxorubicin	[Ouabain results in increased expression of ABCB1] which results in decreased susceptibility to Doxorubicin	19647009
D004317	Doxorubicin	[Paclitaxel results in increased expression of ABCB1] which results in decreased susceptibility to Doxorubicin	21833476
D004317	Doxorubicin	Paliperidone Palmitate inhibits the reaction [ABCB1 protein results in decreased export of Doxorubicin]	16936711
D004317	Doxorubicin	Parathion inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	8917702
D004317	Doxorubicin	pluronic block copolymer p85 inhibits the reaction [Doxorubicin results in increased expression of ABCB1 protein]	16579640
D004317	Doxorubicin	psorospermin inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	7083125
D004317	Doxorubicin	[Quercetin co-treated with Doxorubicin] results in decreased expression of ABCB1 protein	25339540
D004317	Doxorubicin	Quercetin inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]	20438634; 20438634;
D004317	Doxorubicin	Quercetin inhibits the reaction [Doxorubicin results in increased expression of ABCB1 mRNA]	25687049
D004317	Doxorubicin	[RAB6C protein affects the expression of ABCB1 mRNA] which affects the susceptibility to Doxorubicin	18992151
D004317	Doxorubicin	[Resveratrol co-treated with Doxorubicin] results in decreased expression of ABCB1 mRNA	24161697
D004317	Doxorubicin	[[Resveratrol co-treated with Doxorubicin] results in decreased expression of ABCB1 mRNA] which results in increased uptake of Doxorubicin	24161697
D004317	Doxorubicin	[Resveratrol results in increased susceptibility to Doxorubicin] which results in decreased expression of ABCB1 mRNA	24926353
D004317	Doxorubicin	[Resveratrol results in increased susceptibility to Doxorubicin] which results in decreased expression of ABCB1 protein	24926353
D004317	Doxorubicin	[Rifampin binds to and results in increased activity of NR1I2 protein] promotes the reaction [ABCB1 protein results in decreased uptake of Doxorubicin]	20041327
D004317	Doxorubicin	Risperidone inhibits the reaction [ABCB1 protein results in decreased export of Doxorubicin]	16936711
D004317	Doxorubicin	terameprocol inhibits the reaction [Doxorubicin results in increased expression of ABCB1 mRNA]	16544145
D004317	Doxorubicin	[Tiopronin results in decreased expression of ABCB1 protein] which results in increased susceptibility to Doxorubicin	21657271
D004317	Doxorubicin	[[Tretinoin co-treated with romidepsin] results in increased expression of ABCB1 mRNA] which results in decreased susceptibility to Doxorubicin	16223781
D004317	Doxorubicin	tryptoquivaline inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	18829547
D004317	Doxorubicin	valspodar inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	17947497
D004317	Doxorubicin	valspodar inhibits the reaction [ABCB1 protein results in decreased uptake of Doxorubicin]	17947497
D004317	Doxorubicin	valspodar inhibits the reaction [[[Tretinoin co-treated with romidepsin] results in increased expression of ABCB1 mRNA] which results in decreased susceptibility to Doxorubicin]	16223781
D004317	Doxorubicin	Verapamil inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	17947497; 22233293; 24321342; 25058526; 7083125;
D004317	Doxorubicin	Verapamil inhibits the reaction [ABCB1 protein results in decreased uptake of Doxorubicin]	17526808; 17947497;
D004317	Doxorubicin	Verapamil inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	8917702
D004317	Doxorubicin	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Doxorubicin]	12708479
D004317	Doxorubicin	Verapamil inhibits the reaction [Doxorubicin results in increased activity of ABCB1 protein]	17526808
D004317	Doxorubicin	[Verapamil results in decreased activity of ABCB1 protein] which results in increased susceptibility to Doxorubicin	10571255
D004317	Doxorubicin	withaferin A inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]	20438634; 20438634;
D004317	Doxorubicin	[Doxorubicin co-treated with polyisohexylcyanoacrylate] results in increased expression of ABCB1 mRNA	15826724
D004317	Doxorubicin	Doxorubicin results in increased expression of ABCB1 mRNA	15826724; 19714248;
D004317	Doxorubicin	[Verapamil results in decreased expression of ABCB1] promotes the reaction [Doxorubicin results in increased activity of CASP3 protein]	15861398
D004317	Doxorubicin	[Verapamil results in decreased expression of ABCB1] promotes the reaction [Doxorubicin results in increased activity of CASP7 protein]	15861398
D004317	Doxorubicin	zinc chloride inhibits the reaction [Doxorubicin results in increased expression of ABCB1 mRNA]	19714248
D004317	Doxorubicin	ABCB1 protein results in decreased susceptibility to Doxorubicin	11455017
D004317	Doxorubicin	ABCB1 protein results in increased secretion of Doxorubicin	15937726
D004317	Doxorubicin	Doxorubicin affects the activity of ABCB1 protein	15937726
D004317	Doxorubicin	Doxorubicin results in increased expression of ABCB1 mRNA	12187937
D004317	Doxorubicin	Tamoxifen affects the reaction [ABCB1 protein results in increased secretion of Doxorubicin]	15937726
D004317	Doxorubicin	Tamoxifen inhibits the reaction [Doxorubicin affects the activity of ABCB1 protein]	15937726
D004317	Doxorubicin	ABCB1 protein results in decreased susceptibility to Doxorubicin	15906164
D004317	Doxorubicin	ABCB1 results in decreased susceptibility to Doxorubicin	18451141
D004318	Doxycycline	Doxycycline results in decreased expression of ABCB1 protein	11147995
C066425	efonidipine	efonidipine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
C083501	Elacridar	Elacridar binds to and results in decreased activity of ABCB1 protein	23976943
C083501	Elacridar	[Elacridar binds to and results in decreased activity of ABCB1 protein] which results in decreased export of amprenavir	23976943
C083501	Elacridar	[Elacridar binds to and results in decreased activity of ABCB1 protein] which results in decreased export of Digoxin	23976943
C083501	Elacridar	[Elacridar binds to and results in decreased activity of ABCB1 protein] which results in decreased export of Vinblastine	23976943
C083501	Elacridar	Elacridar inhibits the reaction [ABCB1 protein affects the transport of 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine]	20522663
C083501	Elacridar	Elacridar inhibits the reaction [ABCB1 protein results in increased export of Estriol]	15290871
C083501	Elacridar	Elacridar inhibits the reaction [ABCB1 protein results in increased export of Estrone]	15290871
C083501	Elacridar	Elacridar inhibits the reaction [ABCB1 protein results in increased secretion of Aldosterone]	22464980
C083501	Elacridar	Elacridar inhibits the reaction [ABCB1 protein results in increased secretion of Beclomethasone]	22464980
C083501	Elacridar	Elacridar inhibits the reaction [ABCB1 protein results in increased secretion of Dexamethasone]	22464980
C083501	Elacridar	Elacridar inhibits the reaction [ABCB1 protein results in increased secretion of Fluticasone]	22464980
C083501	Elacridar	Elacridar inhibits the reaction [ABCB1 protein results in increased secretion of Hydrocortisone]	22464980
C083501	Elacridar	Elacridar inhibits the reaction [ABCB1 protein results in increased secretion of Methylprednisolone]	22464980
C083501	Elacridar	Elacridar inhibits the reaction [ABCB1 protein results in increased secretion of Prednisone]	22464980
C083501	Elacridar	Elacridar inhibits the reaction [ABCB1 protein results in increased transport of huperzine A]	28587984
C083501	Elacridar	Elacridar inhibits the reaction [ABCB1 protein results in increased transport of Quinacrine]	16581945
C083501	Elacridar	Elacridar results in decreased activity of ABCB1 protein	15832500; 25844889;
C083501	Elacridar	[Elacridar results in decreased activity of ABCB1 protein] which results in increased uptake of Digoxin	25844889
C083501	Elacridar	Elacridar results in decreased export of [ABCB1 protein results in increased transport of Ethinyl Estradiol]	15290871
C083501	Elacridar	Elacridar results in decreased activity of ABCB1 protein	15860656; 19053318;
C443359	emamectin	emamectin inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	25865432
C443359	emamectin	emamectin results in decreased activity of ABCB1 protein	25865432
C108024	emamectin benzoate	emamectin benzoate results in increased expression of ABCB1 mRNA	17350696; 21867772;
C108024	emamectin benzoate	emamectin benzoate results in decreased activity of ABCB1 protein	24316435
C468987	emodepside	ABCB1 protein affects the susceptibility to emodepside	25660379
D004642	Emodin	Emodin inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	24380838
D004726	Endosulfan	Endosulfan results in increased activity of ABCB1 protein	17490606
D004726	Endosulfan	tetramethylrosamine inhibits the reaction [ABCB1 protein results in increased transport of Endosulfan]	17490606
D004726	Endosulfan	ABCB1 protein results in decreased susceptibility to Endosulfan	8917702
D004726	Endosulfan	ABCB1 protein results in increased export of Endosulfan	8917702
D004726	Endosulfan	Diazinon promotes the reaction [Endosulfan inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
D004726	Endosulfan	Diazinon promotes the reaction [Endosulfan results in decreased activity of ABCB1 protein]	21783720
D004726	Endosulfan	Endosulfan binds to ABCB1 protein	8917702
D004726	Endosulfan	[Endosulfan co-treated with Verapamil] inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
D004726	Endosulfan	[Endosulfan co-treated with Verapamil] results in decreased activity of ABCB1 protein	21783720
D004726	Endosulfan	Endosulfan inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	8917702
D004726	Endosulfan	Endosulfan inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
D004726	Endosulfan	Endosulfan inhibits the reaction [phosalone inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
D004726	Endosulfan	Endosulfan inhibits the reaction [phosalone results in decreased activity of ABCB1 protein]	21783720
D004726	Endosulfan	Endosulfan metabolite results in decreased activity of ABCB1 protein	23169446
D004726	Endosulfan	Endosulfan promotes the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
D004726	Endosulfan	Endosulfan promotes the reaction [propiconazole results in decreased activity of ABCB1 protein]	21783720
D004726	Endosulfan	Endosulfan results in decreased activity of ABCB1 protein	21783720
D004726	Endosulfan	phosalone inhibits the reaction [Endosulfan inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
D004726	Endosulfan	phosalone inhibits the reaction [Endosulfan results in decreased activity of ABCB1 protein]	21783720
D004726	Endosulfan	propiconazole promotes the reaction [Endosulfan inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
D004726	Endosulfan	propiconazole promotes the reaction [Endosulfan results in decreased activity of ABCB1 protein]	21783720
D004731	Endotoxins	Endotoxins results in decreased expression of ABCB1 protein	15740733
C040240	enkephalin-Leu, Ala(2)-melphalan methyl ester-	ABCB1 protein affects the transport of enkephalin-Leu, Ala(2)-melphalan methyl ester- analog	12134948; 12134949;
D000077422	Enrofloxacin	[Verapamil results in decreased activity of ABCB1 protein] which results in increased uptake of Enrofloxacin	24498193
C045651	epigallocatechin gallate	epigallocatechin gallate results in decreased expression of ABCB1 mRNA	18851785
C045651	epigallocatechin gallate	epigallocatechin gallate results in decreased expression of ABCB1 protein	20149610
D015251	Epirubicin	3',4',7-trihydroxyisoflavone inhibits the reaction [Epirubicin results in increased expression of ABCB1 mRNA]	22914566
D015251	Epirubicin	ABCB1 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide]	12576456
D015251	Epirubicin	[Epirubicin analog co-treated with chrysophsin analog] results in increased expression of ABCB1 mRNA	26335193
D015251	Epirubicin	Epirubicin analog results in increased expression of ABCB1 mRNA	26335193
D015251	Epirubicin	[Epirubicin co-treated with chrysophsin] results in increased expression of ABCB1 mRNA	26335193
D015251	Epirubicin	Epirubicin results in increased expression of ABCB1 mRNA	22914566; 23867903; 26335193;
D015251	Epirubicin	formononetin inhibits the reaction [Epirubicin results in increased expression of ABCB1 mRNA]	23867903
D015251	Epirubicin	[Diethylnitrosamine co-treated with Epirubicin] results in increased expression of ABCB1 protein	11818250
C007619	eriodictyol	[ABCB1 protein results in decreased susceptibility to Doxorubicin] affects the reaction [eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]]	20438634
C007619	eriodictyol	eriodictyol inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]	20438634; 20438634;
D004917	Erythromycin	Erythromycin inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]	12235267
D004917	Erythromycin	Erythromycin inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	25268938
D004917	Erythromycin	ABCB1 protein affects the transport of Erythromycin	15304119
D004917	Erythromycin	Erythromycin results in decreased activity of ABCB1 protein	11724091
D004918	Erythromycin Estolate	Erythromycin Estolate results in increased expression of ABCB1 mRNA	17522070
D004923	Erythrosine	Erythrosine results in decreased activity of ABCB1 protein	20041016
D004958	Estradiol	Dactinomycin inhibits the reaction [Estradiol results in increased expression of ABCB1 mRNA]	19813763
D004958	Estradiol	Dactinomycin inhibits the reaction [Estradiol results in increased expression of ABCB1 protein]	19813763
D004958	Estradiol	EGF protein promotes the reaction [Estradiol results in decreased expression of ABCB1 mRNA]	24758408
D004958	Estradiol	ESR1 protein affects the reaction [Estradiol results in decreased expression of ABCB1 protein]	16925584
D004958	Estradiol	Estradiol results in decreased expression of ABCB1 mRNA	24758408
D004958	Estradiol	[Estradiol results in decreased expression of ABCB1 protein] which results in increased uptake of and results in increased susceptibility to Vincristine	16925584
D004958	Estradiol	Estradiol results in increased expression of ABCB1 mRNA	15290871; 19813763; 20106945;
D004958	Estradiol	Estradiol results in increased expression of ABCB1 protein	19580841; 19813763;
D004958	Estradiol	Tamoxifen inhibits the reaction [Estradiol results in decreased expression of ABCB1 protein]	16925584
D004958	Estradiol	Estradiol results in increased expression of ABCB1 mRNA	27569056
C025483	estradiol-17 beta-glucuronide	ABCB1 affects the susceptibility to estradiol-17 beta-glucuronide	9794924
C025483	estradiol-17 beta-glucuronide	ABCB1 results in increased transport of estradiol-17 beta-glucuronide	9794924
C025483	estradiol-17 beta-glucuronide	Daunorubicin inhibits the reaction [ABCB1 results in increased transport of estradiol-17 beta-glucuronide]	9794924
C025483	estradiol-17 beta-glucuronide	estriol-16 alpha-(beta-D-glucuronide) inhibits the reaction [ABCB1 results in increased transport of estradiol-17 beta-glucuronide]	9794924
C025483	estradiol-17 beta-glucuronide	estriol 17-glucuronide inhibits the reaction [ABCB1 results in increased transport of estradiol-17 beta-glucuronide]	9794924
D004964	Estriol	ABCB1 protein results in increased export of Estriol	15290871
D004964	Estriol	Elacridar inhibits the reaction [ABCB1 protein results in increased export of Estriol]	15290871
D004964	Estriol	Estriol results in increased expression of ABCB1 mRNA	15290871
D004964	Estriol	Estriol results in increased expression of ABCB1 protein	15290871
C012961	estriol-16 alpha-(beta-D-glucuronide)	estriol-16 alpha-(beta-D-glucuronide) inhibits the reaction [ABCB1 results in increased transport of estradiol-17 beta-glucuronide]	9794924
C035954	estriol 17-glucuronide	estriol 17-glucuronide inhibits the reaction [ABCB1 results in increased transport of estradiol-17 beta-glucuronide]	9794924
D004970	Estrone	ABCB1 protein results in increased export of Estrone	15290871
D004970	Estrone	Elacridar inhibits the reaction [ABCB1 protein results in increased export of Estrone]	15290871
D004970	Estrone	Estrone results in decreased expression of ABCB1 protein	16925584
D004970	Estrone	Estrone results in increased expression of ABCB1 mRNA	15290871
D004970	Estrone	Estrone results in increased expression of ABCB1 protein	15290871
D004997	Ethinyl Estradiol	ABCB1 protein results in increased export of Ethinyl Estradiol	15290871
D004997	Ethinyl Estradiol	Elacridar results in decreased export of [ABCB1 protein results in increased transport of Ethinyl Estradiol]	15290871
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of ABCB1 mRNA	15290871; 24685904;
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of ABCB1 protein	15290871
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of and results in increased activity of ABCB1 protein	24685904
D004997	Ethinyl Estradiol	Fulvestrant inhibits the reaction [Ethinyl Estradiol results in increased expression of ABCB1 protein]	24685904
D005033	Ethylmaleimide	Ethylmaleimide results in decreased activity of ABCB1 protein	2900677
D005047	Etoposide	ABCB1 exon polymorphism affects the susceptibility to Etoposide	12969965
D005047	Etoposide	[Celecoxib results in decreased expression of ABCB1] which results in increased susceptibility to Etoposide	19562670
D005047	Etoposide	Etoposide results in increased expression of ABCB1 mRNA	27570640
D005047	Etoposide	Etoposide results in increased expression of ABCB1 protein	15239124; 27840903;
D005047	Etoposide	[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]	19047049
D005047	Etoposide	[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]	19047049
D005047	Etoposide	[ABCB1 protein co-treated with MGMT protein mutant form] results in decreased susceptibility to Etoposide	16733832
D005047	Etoposide	Verapamil inhibits the reaction [[ABCB1 protein co-treated with MGMT protein mutant form] results in decreased susceptibility to Etoposide]	16733832
D000068338	Everolimus	ABCB1 polymorphism affects the susceptibility to Everolimus	27169792
C049639	evodiamine	evodiamine inhibits the reaction [TNF protein results in increased expression of ABCB1 protein]	15710601
D005273	Fenbendazole	Fenbendazole affects the expression of ABCB1 mRNA	26366864
D011345	Fenofibrate	Fenofibrate inhibits the reaction [ABCB1 protein results in increased transport of Vincristine]	16316932
C052034	fenoxycarb	fenoxycarb inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
C052034	fenoxycarb	fenoxycarb results in decreased activity of ABCB1 protein	21783720
D005283	Fentanyl	ABCB1 protein results in increased transport of Fentanyl	29669042
D005283	Fentanyl	tariquidar inhibits the reaction [ABCB1 protein results in increased transport of Fentanyl]	29669042
D005283	Fentanyl	ABCB1 protein results in increased susceptibility to Fentanyl	29669042
C017690	fenvalerate	fenvalerate results in increased activity of ABCB1 protein	17490606
C017690	fenvalerate	tetramethylrosamine inhibits the reaction [ABCB1 protein results in increased transport of fenvalerate]	17490606
C017690	fenvalerate	fenvalerate inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
C017690	fenvalerate	fenvalerate results in decreased activity of ABCB1 protein	21783720
C020326	ferric nitrilotriacetate	ferric nitrilotriacetate inhibits the reaction [Asbestos, Crocidolite results in increased expression of ABCB1 protein]	18385176
C020326	ferric nitrilotriacetate	ferric nitrilotriacetate inhibits the reaction [Razoxane results in increased expression of ABCB1 protein]	18385176
C093230	fexofenadine	ABCB1 protein results in decreased uptake of fexofenadine	18299336
C093230	fexofenadine	ABCB1 gene SNP affects the susceptibility to fexofenadine	15536457
C093230	fexofenadine	Itraconazole promotes the reaction [ABCB1 gene SNP affects the susceptibility to fexofenadine]	16084853
C093230	fexofenadine	Plant Extracts promotes the reaction [ABCB1 protein results in increased transport of fexofenadine]	12545142
C014558	flunixin meglumine	flunixin meglumine affects the expression of ABCB1 mRNA	26366864
D005456	Fluorescent Dyes	ABCB1 protein results in increased export of Fluorescent Dyes	27450509
D005456	Fluorescent Dyes	Cyclosporine inhibits the reaction [ABCB1 protein results in increased export of Fluorescent Dyes]	27450509
D005456	Fluorescent Dyes	Tobacco Smoke Pollution inhibits the reaction [ABCB1 protein results in increased export of Fluorescent Dyes]	27450509
C007740	fluorexon	ABCB1 protein results in increased export of fluorexon	16442095
C007740	fluorexon	ABCB1 protein results in increased secretion of fluorexon	12235267
C007740	fluorexon	Beclomethasone inhibits the reaction [ABCB1 protein results in increased export of fluorexon]	16442095
C007740	fluorexon	[Carvedilol results in decreased activity of ABCB1 protein] which results in increased uptake of fluorexon	10571255
C007740	fluorexon	Clotrimazole inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]	12235267
C007740	fluorexon	Cyclosporine inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]	12235267
C007740	fluorexon	desisobutyrylciclesonide inhibits the reaction [ABCB1 protein results in increased export of fluorexon]	16442095
C007740	fluorexon	Ketoconazole inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]	12235267
C007740	fluorexon	Miconazole inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]	12235267
C007740	fluorexon	Mometasone Furoate inhibits the reaction [ABCB1 protein results in increased export of fluorexon]	16442095
C007740	fluorexon	Reserpine inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]	12235267
C007740	fluorexon	Troleandomycin inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]	12235267
C007740	fluorexon	Verapamil inhibits the reaction [ABCB1 protein results in increased export of fluorexon]	16442095
C007740	fluorexon	[Verapamil results in decreased activity of ABCB1 protein] which results in increased uptake of fluorexon	10571255
C053629	fluoroaluminum	fluoroaluminum promotes the reaction [ABCB1 protein mutant form binds to 8-azidoadenosine 5'-triphosphate]	11027628
D005472	Fluorouracil	ABCB1 gene SNP affects the susceptibility to [Cisplatin co-treated with Fluorouracil]	21332314
D005472	Fluorouracil	ABCB1 protein affects the susceptibility to [Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil]	12576456
D005472	Fluorouracil	ABCB1 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide]	12576456
D005472	Fluorouracil	Fluorouracil results in decreased expression of ABCB1 mRNA	17287894
D005472	Fluorouracil	Fluorouracil results in increased expression of ABCB1 protein	15239124
D005472	Fluorouracil	[Paclitaxel results in increased expression of ABCB1] which results in decreased susceptibility to Fluorouracil	21833476
D005475	Flupenthixol	Flupenthixol analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	7905786
D005475	Flupenthixol	Flupenthixol analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]	7905786
D005475	Flupenthixol	Flupenthixol analog results in decreased activity of ABCB1 protein	7905786
D005475	Flupenthixol	Flupenthixol analog results in decreased activity of ABCB1 protein mutant form	12711602
D005485	Flutamide	[Flutamide results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA	20041327
D005485	Flutamide	Flutamide results in increased expression of ABCB1 protein	20041327
D005485	Flutamide	NR1I2 protein promotes the reaction [Flutamide results in increased expression of and results in increased activity of ABCB1 protein]	20041327
D005485	Flutamide	Flutamide results in increased expression of ABCB1 mRNA	24136188
D000068298	Fluticasone	ABCB1 protein results in increased secretion of Fluticasone	22464980
D000068298	Fluticasone	Elacridar inhibits the reaction [ABCB1 protein results in increased secretion of Fluticasone]	22464980
D000068298	Fluticasone	Fluticasone results in increased expression of ABCB1 protein	22464980
D000068298	Fluticasone	valspodar inhibits the reaction [ABCB1 protein results in increased secretion of Fluticasone]	22464980
D005505	Food Coloring Agents	Food Coloring Agents results in decreased activity of ABCB1 protein	18686201; 20041016;
C007768	formononetin	Acetylcysteine inhibits the reaction [formononetin results in increased expression of ABCB1 mRNA]	23867903
C007768	formononetin	formononetin affects the activity of ABCB1 protein	15796199
C007768	formononetin	formononetin inhibits the reaction [Epirubicin results in increased expression of ABCB1 mRNA]	23867903
C007768	formononetin	formononetin results in increased expression of ABCB1 mRNA	23867903
C080222	FPEPIR regimen	FPEPIR regimen results in increased expression of ABCB1 mRNA	16026610
C080222	FPEPIR regimen	FPEPIR regimen results in increased expression of ABCB1 protein	16026610
D000077267	Fulvestrant	Fulvestrant inhibits the reaction [Ethinyl Estradiol results in increased expression of ABCB1 protein]	24685904
D000077267	Fulvestrant	Fulvestrant inhibits the reaction [Genistein results in increased expression of ABCB1 protein]	24685904
D000077267	Fulvestrant	Fulvestrant results in increased expression of ABCB1 protein	24685904
C056933	fumonisin B1	fumonisin B1 inhibits the reaction [nickel chloride results in increased expression of ABCB1 protein]	24448832
D037341	Fumonisins	Fumonisins results in increased expression of ABCB1 mRNA	28082229
D005672	Fusidic Acid	Fusidic Acid inhibits the reaction [ABCB1 protein results in increased export of Digoxin]	26888941
D000077206	Gabapentin	Gabapentin results in decreased activity of ABCB1 protein	18408562
C037032	galangin	galangin results in increased expression of ABCB1 mRNA	26238175
D005707	Gallic Acid	Gallic Acid results in decreased expression of ABCB1 protein	20513373
D005711	Gallopamil	Gallopamil binds to ABCB1 protein	10783826
D005711	Gallopamil	Gallopamil metabolite binds to ABCB1 protein	10783826
C052659	gambogic acid	Acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of CASP7 protein]	25824409
C052659	gambogic acid	Acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of PARP1 protein]	25824409
C052659	gambogic acid	gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]	25824409
C052659	gambogic acid	[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of CASP7 protein	25824409
C052659	gambogic acid	[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of PARP1 protein	25824409
C018669	gamma-terpinene	gamma-terpinene inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D019833	Genistein	Fulvestrant inhibits the reaction [Genistein results in increased expression of ABCB1 protein]	24685904
D019833	Genistein	Genistein results in increased expression of ABCB1 mRNA	24685904
D019833	Genistein	Genistein results in increased expression of ABCB1 protein	18634814
D019833	Genistein	Genistein results in increased expression of and results in increased activity of ABCB1 protein	24685904
D005839	Gentamicins	Gentamicins results in decreased expression of ABCB1 mRNA	20623750
C002963	geranylgeranyl pyrophosphate	geranylgeranyl pyrophosphate inhibits the reaction [kuwanon G results in increased expression of ABCB1 protein]	29355567
C048393	germacrone	ABCB1 protein inhibits the reaction [germacrone results in increased susceptibility to Doxorubicin]	29655913
C048393	germacrone	germacrone inhibits the reaction [Doxorubicin results in increased expression of ABCB1 mRNA]	29655913
C048393	germacrone	germacrone inhibits the reaction [Doxorubicin results in increased expression of ABCB1 protein]	29655913
C007845	gingerol	gingerol inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	18385293
C063170	Ginkgo biloba extract	Ginkgo biloba extract results in increased expression of ABCB1 mRNA	19034627
C477042	ginkgolide A	ginkgolide A results in increased expression of ABCB1 mRNA	19034627
C045856	ginkgolide B	ginkgolide B results in increased expression of ABCB1 mRNA	19034627; 26775663;
C045856	ginkgolide B	NR1I2 protein affects the reaction [ginkgolide B results in increased expression of ABCB1 mRNA]	26775663
C045856	ginkgolide B	sulforafan inhibits the reaction [ginkgolide B results in increased expression of ABCB1 mRNA]	26775663
C407883	ginsenoside F2	ginsenoside F2 analog inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	24380838
D005897	Glafenine	Glafenine results in decreased expression of ABCB1 mRNA	24136188
C005004	glaucine	glaucine results in increased activity of ABCB1 protein	23273999
C018549	globotriaosylceramide	ABCB1 protein results in increased chemical synthesis of globotriaosylceramide	14662772
C018549	globotriaosylceramide	Cyclosporine inhibits the reaction [ABCB1 protein results in increased chemical synthesis of globotriaosylceramide]	14662772
C018549	globotriaosylceramide	Ketoconazole inhibits the reaction [ABCB1 protein results in increased chemical synthesis of globotriaosylceramide]	14662772
D005947	Glucose	Glucose results in decreased expression of ABCB1 protein	22363694
D005963	Glucosylceramides	ABCB1 protein results in increased chemical synthesis of Glucosylceramides	14662772
D005963	Glucosylceramides	Cyclosporine inhibits the reaction [ABCB1 protein results in increased chemical synthesis of Glucosylceramides]	14662772
D005963	Glucosylceramides	Ketoconazole inhibits the reaction [ABCB1 protein results in increased chemical synthesis of Glucosylceramides]	14662772
D005990	Glycerol	Glycerol affects the metabolism of and affects the localization of ABCB1 protein mutant form	22184139
D006034	Glycyrrhetinic Acid	Glycyrrhetinic Acid inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
C000593030	GSK-J4	GSK-J4 results in increased expression of ABCB1 mRNA	29301935
D006160	Guanosine Triphosphate	ABCB1 protein results in increased hydrolysis of Guanosine Triphosphate	2900677
D006220	Haloperidol	Haloperidol inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	15946544
D006220	Haloperidol	Haloperidol results in decreased activity of ABCB1 protein	16810505
D006220	Haloperidol	Haloperidol results in decreased expression of ABCB1 mRNA	15946544
D006533	Heptachlor	Heptachlor results in increased expression of ABCB1 mRNA	24464585
D001556	Hexachlorocyclohexane	Hexachlorocyclohexane results in increased expression of ABCB1 mRNA	24464585
C050426	huperzine A	ABCB1 protein results in increased transport of huperzine A	28587984
C050426	huperzine A	Elacridar inhibits the reaction [ABCB1 protein results in increased transport of huperzine A]	28587984
C050426	huperzine A	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of huperzine A]	28587984
D006820	Hyaluronic Acid	[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 mRNA	19047049
D006820	Hyaluronic Acid	[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein	19047049
D006820	Hyaluronic Acid	[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]	19047049
D006820	Hyaluronic Acid	[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]	19047049
D006820	Hyaluronic Acid	[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 mRNA	19047049
D006820	Hyaluronic Acid	[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein	19047049
D006820	Hyaluronic Acid	[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]	19047049
D006820	Hyaluronic Acid	[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]	19047049
D006820	Hyaluronic Acid	Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 mRNA]	19047049
D006820	Hyaluronic Acid	Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein]	19047049
D006820	Hyaluronic Acid	Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 mRNA]	19047049
D006820	Hyaluronic Acid	Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein]	19047049
C041642	hydramethylnon	hydramethylnon binds to ABCB1 protein	8917702
C041642	hydramethylnon	hydramethylnon inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	8917702
D006843	Hydrocarbons, Chlorinated	ABCB1 gene polymorphism affects the metabolism of Hydrocarbons, Chlorinated	20558393
D006843	Hydrocarbons, Chlorinated	ABCB1 gene SNP affects the susceptibility to Hydrocarbons, Chlorinated	26457621
D006854	Hydrocortisone	[valspodar results in decreased activity of ABCB1 protein] promotes the reaction [Doxorubicin results in decreased secretion of Hydrocortisone]	10898547
D006854	Hydrocortisone	[valspodar results in decreased activity of ABCB1 protein] promotes the reaction [Mitotane results in decreased secretion of Hydrocortisone]	10898547
D006854	Hydrocortisone	ABCB1 protein results in increased secretion of Hydrocortisone	22464980
D006854	Hydrocortisone	Elacridar inhibits the reaction [ABCB1 protein results in increased secretion of Hydrocortisone]	22464980
D006854	Hydrocortisone	valspodar inhibits the reaction [ABCB1 protein results in increased secretion of Hydrocortisone]	22464980
D006861	Hydrogen Peroxide	Hydrogen Peroxide affects the expression of ABCB1 mRNA	26519223
C058309	hypaconitine	ABCB1 protein results in increased transport of hypaconitine	23200901
C058309	hypaconitine	[Cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of hypaconitine	23200901
C058309	hypaconitine	[Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of hypaconitine	23200901
C001654	hyperforin	hyperforin inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir]	15266218
C001654	hyperforin	hyperforin results in increased expression of ABCB1	16005588
C001654	hyperforin	hyperforin results in increased expression of ABCB1 mRNA	24259679
C004965	hypericin	hypericin inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir]	15266218
C004965	hypericin	hypericin results in increased expression of ABCB1	16005588
D007052	Ibuprofen	Ibuprofen results in increased expression of ABCB1 mRNA	22559005
D007052	Ibuprofen	Ibuprofen results in decreased expression of ABCB1 mRNA	21872554
D007069	Ifosfamide	[Ifosfamide results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA	20041327
D007069	Ifosfamide	Ifosfamide results in increased expression of ABCB1 protein	20041327
D007069	Ifosfamide	NR1I2 protein promotes the reaction [Ifosfamide results in increased expression of ABCB1 protein]	20041327
D000068877	Imatinib Mesylate	ABCB1 protein affects the susceptibility to Imatinib Mesylate	28623111
D000068877	Imatinib Mesylate	ABCB1 protein results in decreased susceptibility to Imatinib Mesylate	24954033
D000068877	Imatinib Mesylate	Imatinib Mesylate results in increased expression of ABCB1 mRNA	15970668
D000068877	Imatinib Mesylate	Imatinib Mesylate results in increased expression of and results in increased activity of ABCB1 protein	15970668
D007099	Imipramine	Imipramine affects the expression of ABCB1 mRNA	18355885
C016517	indole-3-carbinol	indole-3-carbinol results in decreased expression of ABCB1	16082211
D007306	Insecticides	ABCB1 gene polymorphism affects the metabolism of Insecticides	20558393
D007306	Insecticides	Insecticides results in decreased activity of ABCB1 protein	23169446
D007461	Iodoacetates	[Sodium Azide co-treated with Iodoacetates] inhibits the reaction [ABCB1 protein results in increased export of Daunorubicin]	12526924
D015759	Ionomycin	[Tetradecanoylphorbol Acetate co-treated with Ionomycin] affects the expression of ABCB1 mRNA	25613284
D000077146	Irinotecan	ABCB1 exon SNP affects the susceptibility to and affects the metabolism of Irinotecan	15801936
D000077146	Irinotecan	ABCB1 gene polymorphism affects the susceptibility to Irinotecan	12960109
D000077146	Irinotecan	ABCB1 protein affects the export of Irinotecan	15655543
D000077146	Irinotecan	ABCB1 protein results in decreased susceptibility to Irinotecan	16815871
D000077146	Irinotecan	ABCB1 protein results in increased export of Irinotecan	16271446
C000603302	isopropyl 5,12-hydroxypentadeca-8,10-dien-6,14-diynoate	isopropyl 5,12-hydroxypentadeca-8,10-dien-6,14-diynoate results in decreased activity of ABCB1 protein	25844889
C000603302	isopropyl 5,12-hydroxypentadeca-8,10-dien-6,14-diynoate	[isopropyl 5,12-hydroxypentadeca-8,10-dien-6,14-diynoate results in decreased activity of ABCB1 protein] which results in increased uptake of Digoxin	25844889
C015959	isosafrole	isosafrole results in increased expression of ABCB1 protein	8632764
D015474	Isotretinoin	[Vorinostat co-treated with Isotretinoin] results in increased expression of ABCB1 mRNA	18769122
D017964	Itraconazole	ABCB1 protein affects the transport of Itraconazole	15905803
D017964	Itraconazole	Itraconazole affects the activity of ABCB1 protein	15964336
D017964	Itraconazole	Itraconazole inhibits the reaction [ABCB1 protein affects the transport of Digoxin]	15969931
D017964	Itraconazole	Itraconazole promotes the reaction [ABCB1 gene SNP affects the susceptibility to fexofenadine]	16084853
D017964	Itraconazole	Itraconazole results in decreased activity of ABCB1 protein	15905803; 15969931;
D007559	Ivermectin	ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of ALB mRNA]	25419811
D007559	Ivermectin	ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of DAO mRNA]	25419811
D007559	Ivermectin	ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of EBF3 mRNA]	25419811
D007559	Ivermectin	ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of GABRQ mRNA]	25419811
D007559	Ivermectin	ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of GLRA1 mRNA]	25419811
D007559	Ivermectin	ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of KLK6 mRNA]	25419811
D007559	Ivermectin	ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of MAB21L2 mRNA]	25419811
D007559	Ivermectin	ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of SLC10A4 mRNA]	25419811
D007559	Ivermectin	ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of SLC18A2 mRNA]	25419811
D007559	Ivermectin	ABCB1 gene mutant form affects the reaction [Ivermectin affects the expression of TTR mRNA]	25419811
D007559	Ivermectin	ABCB1 gene mutant form results in increased susceptibility to Ivermectin	22834856; 25419811;
D007559	Ivermectin	ABCB1 mutant form results in increased susceptibility to Ivermectin	23186803
D007559	Ivermectin	ABCB1 protein affects the abundance of Ivermectin	20595473
D007559	Ivermectin	ABCB1 protein mutant form results in increased susceptibility to Ivermectin	22924731
D007559	Ivermectin	ABCB1 protein affects the susceptibility to Ivermectin	25660379
D007559	Ivermectin	ABCB1 gene polymorphism affects the abundance of Ivermectin	20595473
D007559	Ivermectin	ABCB1 gene polymorphism affects the susceptibility to Ivermectin	20630055
D007559	Ivermectin	Ivermectin binds to ABCB1 protein	8917702
D007559	Ivermectin	Ivermectin inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	8917702
D007559	Ivermectin	Ivermectin inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	25865432
D007559	Ivermectin	Ivermectin results in decreased activity of ABCB1 protein	25865432
D007559	Ivermectin	Ivermectin results in decreased activity of ABCB1 protein	24316435
C054862	jasmine oil	jasmine oil results in increased expression of ABCB1 mRNA	30071242
C561695	(+)-JQ1 compound	(+)-JQ1 compound results in decreased expression of ABCB1 mRNA	25961927
C561695	(+)-JQ1 compound	(+)-JQ1 compound results in increased expression of ABCB1 mRNA	24796395
C115013	juniper berry oil	juniper berry oil results in increased expression of ABCB1 mRNA	30071242
C410337	K 7174	K 7174 results in increased expression of ABCB1 mRNA	24086573
C006552	kaempferol	kaempferol inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir]	15266218
C006552	kaempferol	ABCB1 protein results in increased transport of kaempferol	15969930
C006552	kaempferol	kaempferol inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]	20438634; 20438634;
C011889	kavain	kavain results in increased activity of ABCB1 protein	16033948
C119620	kenpaullone	kenpaullone results in increased expression of ABCB1 protein	18624906
D007654	Ketoconazole	Ketoconazole results in decreased activity of ABCB1 protein	19754906
D007654	Ketoconazole	[Ketoconazole results in decreased activity of ABCB1 protein] which results in decreased transport of Technetium Tc 99m Sestamibi	19754906
D007654	Ketoconazole	Ketoconazole results in decreased expression of ABCB1 mRNA	22620706
D007654	Ketoconazole	ABCB1 protein results in increased transport of Ketoconazole	23976943
D007654	Ketoconazole	Ketoconazole binds to and results in decreased activity of ABCB1 protein	23976943
D007654	Ketoconazole	[Ketoconazole binds to and results in decreased activity of ABCB1 protein] which results in decreased export of Digoxin	23976943
D007654	Ketoconazole	Ketoconazole inhibits the reaction [3,3'-diindolylmethane results in increased expression of ABCB1 mRNA]	25542144
D007654	Ketoconazole	Ketoconazole inhibits the reaction [ABCB1 protein affects the transport of Digoxin]	15969931
D007654	Ketoconazole	Ketoconazole inhibits the reaction [ABCB1 protein results in increased chemical synthesis of globotriaosylceramide]	14662772
D007654	Ketoconazole	Ketoconazole inhibits the reaction [ABCB1 protein results in increased chemical synthesis of Glucosylceramides]	14662772
D007654	Ketoconazole	Ketoconazole inhibits the reaction [ABCB1 protein results in increased chemical synthesis of Lactosylceramides]	14662772
D007654	Ketoconazole	Ketoconazole inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]	12235267
D007654	Ketoconazole	Ketoconazole inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]	12235267
D007654	Ketoconazole	Ketoconazole inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	17365992
D007654	Ketoconazole	Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 mRNA]]	23707768
D007654	Ketoconazole	Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 protein]]	23707768
D007654	Ketoconazole	Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 mRNA]]	23707768
D007654	Ketoconazole	Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 protein]]	23707768
D007654	Ketoconazole	Ketoconazole inhibits the reaction [Paclitaxel results in increased expression of ABCB1 mRNA]	16819505
D007654	Ketoconazole	Ketoconazole inhibits the reaction [Paclitaxel results in increased expression of ABCB1 protein]	16819505
D007654	Ketoconazole	Ketoconazole inhibits the reaction [Rifampin results in increased expression of ABCB1 mRNA]	16819505; 25542144;
D007654	Ketoconazole	Ketoconazole inhibits the reaction [Rifampin results in increased expression of ABCB1 protein]	16819505; 20624464;
D007654	Ketoconazole	Ketoconazole inhibits the reaction [Spironolactone results in increased expression of ABCB1 protein]	21459122
D007654	Ketoconazole	Ketoconazole results in decreased activity of ABCB1 protein	10350002; 15969931; 19070657; 25844889;
D007654	Ketoconazole	[Ketoconazole results in decreased activity of ABCB1 protein] which results in increased uptake of Digoxin	25844889
D007654	Ketoconazole	Ketoconazole results in decreased expression of ABCB1 mRNA	17365992
D007654	Ketoconazole	Ketoconazole inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCB1 mRNA]	16819505
D007654	Ketoconazole	Ketoconazole inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCB1 protein]	16819505
D007654	Ketoconazole	Ketoconazole affects the expression of ABCB1 mRNA	18355885
C072105	KN 93	KN 93 inhibits the reaction [Digoxin results in increased expression of ABCB1 protein]	19647009
C072105	KN 93	KN 93 inhibits the reaction [Ouabain results in increased expression of ABCB1 protein]	19647009
C057416	KT 5720	KT 5720 results in decreased activity of ABCB1 protein	15725475
C095194	kuwanon G	geranylgeranyl pyrophosphate inhibits the reaction [kuwanon G results in increased expression of ABCB1 protein]	29355567
C095194	kuwanon G	kuwanon G results in increased expression of ABCB1 mRNA	29355567
C095194	kuwanon G	kuwanon G results in increased expression of ABCB1 protein	29355567
D007741	Labetalol	Labetalol binds to ABCB1 protein	10783826
D007790	Lactosylceramides	ABCB1 protein results in increased chemical synthesis of Lactosylceramides	14662772
D007790	Lactosylceramides	Cyclosporine inhibits the reaction [ABCB1 protein results in increased chemical synthesis of Lactosylceramides]	14662772
D007790	Lactosylceramides	Ketoconazole inhibits the reaction [ABCB1 protein results in increased chemical synthesis of Lactosylceramides]	14662772
D000077213	Lamotrigine	Lamotrigine results in decreased activity of ABCB1 protein	18408562
D064747	Lansoprazole	ABCB1 affects the susceptibility to Lansoprazole	19238367
D000077341	Lapatinib	Lapatinib inhibits the reaction [ABCB1 protein results in increased export of and results in decreased susceptibility to Doxorubicin]	18829547
D000077341	Lapatinib	Lapatinib inhibits the reaction [azidoprazosin binds to ABCB1 protein]	18829547
D000077341	Lapatinib	Lapatinib promotes the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]	18829547
D007854	Lead	ABCB1 gene polymorphism affects the abundance of Lead	25728017
C017461	lead nitrate	lead nitrate results in increased expression of ABCB1 protein	21526414
C017461	lead nitrate	lead nitrate results in increased expression of ABCB1 mRNA	30041384
C052901	lemongrass oil	lemongrass oil affects the expression of ABCB1 mRNA	25976427
C052901	lemongrass oil	lemongrass oil results in increased expression of ABCB1 mRNA	30071242
D000077287	Levetiracetam	Levetiracetam results in decreased activity of ABCB1 protein	18408562
D000077287	Levetiracetam	Amino Acids, Peptides, and Proteins inhibits the reaction [Levetiracetam results in increased expression of ABCB1 protein]	18473823
D000077287	Levetiracetam	Levetiracetam results in increased expression of ABCB1 protein	18473823
D016912	Levonorgestrel	Levonorgestrel results in increased expression of ABCB1 mRNA	15290871
D008070	Lipopolysaccharides	[Lipopolysaccharides co-treated with Resveratrol] results in decreased expression of ABCB1 mRNA	26667767
D008070	Lipopolysaccharides	GCG protein inhibits the reaction [Lipopolysaccharides affects the localization of ABCB1 protein]	28842383
D008070	Lipopolysaccharides	GCG protein inhibits the reaction [Lipopolysaccharides results in decreased expression of ABCB1 mRNA]	28842383
D008070	Lipopolysaccharides	GCG protein inhibits the reaction [Lipopolysaccharides results in decreased expression of and results in decreased activity of ABCB1 protein]	28842383
D008070	Lipopolysaccharides	Lipopolysaccharides affects the localization of ABCB1 protein	28842383
D008070	Lipopolysaccharides	Lipopolysaccharides results in decreased expression of ABCB1 mRNA	28842383
D008070	Lipopolysaccharides	Lipopolysaccharides results in decreased expression of and results in decreased activity of ABCB1 protein	28842383
D018021	Lithium Chloride	Lithium Chloride results in increased expression of ABCB1 protein	18624906
D008095	Lithocholic Acid	Lithocholic Acid results in increased expression of ABCB1 mRNA	19460946
D008095	Lithocholic Acid	VDR protein promotes the reaction [Lithocholic Acid results in increased expression of ABCB1 mRNA]	19460946
D008130	Lomustine	Lomustine results in increased expression of ABCB1 protein	15239124
D008139	Loperamide	ABCB1 protein affects the susceptibility to Loperamide	25660379
D008139	Loperamide	ABCB1 protein results in increased export of Loperamide	28093773
D008139	Loperamide	ABCB1 protein results in increased transport of Loperamide	23976943
D008139	Loperamide	Loperamide binds to ABCB1 protein	23976943
D008139	Loperamide	ABCB1 protein results in increased transport of Loperamide	20604828
D017336	Loratadine	ABCB1 protein results in increased export of Loratadine	12584158
D008148	Lovastatin	ABCB1 protein results in increased transport of Lovastatin	15616150
D008148	Lovastatin	ABCB1 protein results in increased transport of Lovastatin analog	15616150
D008148	Lovastatin	Lovastatin analog inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	15616150
D008148	Lovastatin	Lovastatin analog results in decreased activity of ABCB1 protein	15616150
C533860	macitentan	macitentan results in decreased expression of ABCB1 mRNA	28369585
D008274	Magnesium	Cadmium inhibits the reaction [Magnesium results in increased activity of ABCB1 protein]	2900677
D008274	Magnesium	Calcium inhibits the reaction [Magnesium results in increased activity of ABCB1 protein]	2900677
D008274	Magnesium	Copper inhibits the reaction [Magnesium results in increased activity of ABCB1 protein]	2900677
D008274	Magnesium	Magnesium results in increased activity of ABCB1 protein	2900677
D008274	Magnesium	[Magnesium results in increased activity of ABCB1 protein] which results in increased hydrolysis of Adenosine Triphosphate	2900677
D008274	Magnesium	Nickel inhibits the reaction [Magnesium results in increased activity of ABCB1 protein]	2900677
D008274	Magnesium	Zinc inhibits the reaction [Magnesium results in increased activity of ABCB1 protein]	2900677
D058185	Magnetite Nanoparticles	ABCB1 mutant form promotes the reaction [Magnetite Nanoparticles results in increased susceptibility to Daunorubicin]	20957165
D058185	Magnetite Nanoparticles	[Daunorubicin co-treated with bromotetrandrine co-treated with Magnetite Nanoparticles] results in decreased expression of ABCB1 mRNA	22114476
D058185	Magnetite Nanoparticles	Daunorubicin promotes the reaction [Magnetite Nanoparticles results in decreased expression of ABCB1 protein]	20957165
D058185	Magnetite Nanoparticles	Magnetite Nanoparticles promotes the reaction [ABCB1 mutant form promotes the reaction [Daunorubicin results in decreased expression of ABCB1 mRNA]]	20957165; 20957165;
D058185	Magnetite Nanoparticles	Magnetite Nanoparticles promotes the reaction [ABCB1 mutant form promotes the reaction [Daunorubicin results in decreased expression of ABCB1 protein]]	20957165; 20957165;
D058185	Magnetite Nanoparticles	Magnetite Nanoparticles promotes the reaction [ABCB1 mutant form results in increased susceptibility to Daunorubicin]	20957165
D058185	Magnetite Nanoparticles	Magnetite Nanoparticles promotes the reaction [Daunorubicin promotes the reaction [ABCB1 mutant form results in decreased expression of ABCB1 protein]]	20957165; 20957165;
D058185	Magnetite Nanoparticles	Magnetite Nanoparticles promotes the reaction [Daunorubicin results in decreased expression of ABCB1 mRNA]	20957165
D058185	Magnetite Nanoparticles	Magnetite Nanoparticles promotes the reaction [Daunorubicin results in decreased expression of ABCB1 protein]	20957165
D058185	Magnetite Nanoparticles	Magnetite Nanoparticles results in decreased expression of ABCB1 mRNA	20957165
D058185	Magnetite Nanoparticles	Magnetite Nanoparticles results in decreased expression of ABCB1 protein	20957165
D058185	Magnetite Nanoparticles	[Succimer co-treated with Magnetite Nanoparticles] results in increased expression of ABCB1 mRNA	26378955
D008345	Manganese	Manganese results in increased activity of ABCB1 protein	2900677
D008345	Manganese	[Manganese results in increased activity of ABCB1 protein] which results in increased hydrolysis of Adenosine Triphosphate	2900677
C501277	Mangifera indica extract	Mangifera indica extract results in decreased expression of ABCB1 protein	20513373
C013592	mangiferin	Dichlororibofuranosylbenzimidazole inhibits the reaction [mangiferin results in increased expression of ABCB1 protein]	20513373
C013592	mangiferin	mangiferin results in increased expression of ABCB1 mRNA	20513373
C013592	mangiferin	mangiferin results in increased expression of ABCB1 protein	20513373
C054218	manidipine	manidipine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
D008353	Mannitol	Mannitol inhibits the reaction [Vitamin A results in decreased expression of ABCB1 mRNA]	15327746
C518176	maropitant	ABCB1 protein results in increased export of maropitant	28093773
D008463	Mebendazole	Mebendazole results in decreased expression of ABCB1 mRNA	28606429
D008463	Mebendazole	Mebendazole results in decreased expression of ABCB1 protein	28606429
D015767	Mefloquine	ABCB1 protein binds to and affects the uptake of and affects the secretion of Mefloquine	17015054
D015767	Mefloquine	Mefloquine results in decreased activity of ABCB1 protein	17015054
D008550	Melatonin	Melatonin inhibits the reaction [Methamphetamine results in decreased expression of ABCB1 protein]	28223141
D000077239	Meloxicam	Meloxicam inhibits the reaction [Doxorubicin results in increased activity of ABCB1 protein]	15501994
D000077239	Meloxicam	Meloxicam inhibits the reaction [Doxorubicin results in increased expression of ABCB1 protein]	15501994
C050699	mepirodipine	mepirodipine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
D008627	Mercuric Chloride	Mercuric Chloride results in increased expression of ABCB1 mRNA	22819804
D008627	Mercuric Chloride	Mercuric Chloride affects the expression of ABCB1 mRNA	17083914
D008627	Mercuric Chloride	Mercuric Chloride results in increased activity of ABCB1 protein	23690080
D008627	Mercuric Chloride	Mercuric Chloride results in increased activity of ABCB1 protein	22580103
D008628	Mercury	Mercury results in increased expression of ABCB1 protein	15084411
D008628	Mercury	ABCB1 gene SNP affects the susceptibility to and affects the abundance of Mercury	27262785
C019470	mesaconitine	ABCB1 protein results in increased transport of mesaconitine	23200901
C019470	mesaconitine	[Cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of mesaconitine	23200901
C019470	mesaconitine	[Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of mesaconitine	23200901
C521990	metazachlor	metazachlor results in increased activity of ABCB1 protein	18433974
D008687	Metformin	Metformin inhibits the reaction [Doxorubicin results in increased expression of ABCB1 mRNA]	21054339
D008687	Metformin	Metformin inhibits the reaction [RELA protein results in increased expression of ABCB1 mRNA]	21054339
D008687	Metformin	Metformin inhibits the reaction [TNF protein results in increased expression of ABCB1 mRNA]	21054339
D008687	Metformin	Metformin inhibits the reaction [TNF protein results in increased expression of ABCB1 protein]	21054339
D008687	Metformin	Metformin results in decreased expression of ABCB1 mRNA	21054339
D008687	Metformin	Metformin results in decreased expression of ABCB1 protein	21054339
D008687	Metformin	PRKAA1 protein affects the reaction [Metformin results in decreased expression of ABCB1 protein]	21054339
D008691	Methadone	Methadone affects the activity of ABCB1 protein	19840843
D008691	Methadone	Methadone results in increased expression of ABCB1 protein	19840843
D008691	Methadone	ABCB1 protein affects the susceptibility to Methadone	15089813
D008691	Methadone	ABCB1 protein affects the transport of Methadone	15089813
D008694	Methamphetamine	Melatonin inhibits the reaction [Methamphetamine results in decreased expression of ABCB1 protein]	28223141
D008694	Methamphetamine	Methamphetamine results in decreased expression of ABCB1 protein	28223141
D008715	Methionine	[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCB1 mRNA	24384915
D008715	Methionine	[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCB1 protein	24384915
D008727	Methotrexate	ABCB1 gene polymorphism affects the reaction [Methotrexate results in decreased secretion of IFNG protein]	16321374
D008727	Methotrexate	ABCB1 gene polymorphism affects the reaction [Methotrexate results in decreased secretion of IL2 protein]	16321374
D008727	Methotrexate	ABCB1 gene polymorphism affects the reaction [Methotrexate results in decreased secretion of TNF protein]	16321374
D008727	Methotrexate	ABCB1 gene polymorphism affects the susceptibility to Methotrexate	16321374; 22104130; 25007187;
D008727	Methotrexate	ABCB1 gene polymorphism affects the susceptibility to [Methotrexate co-treated with Methylprednisolone]	16932953
D008727	Methotrexate	ABCB1 gene SNP affects the susceptibility to Methotrexate	18381794; 22859359;
D008727	Methotrexate	ABCB1 polymorphism results in increased susceptibility to Methotrexate	21887680
D008727	Methotrexate	ABCB1 protein affects the susceptibility to [Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil]	12576456
D008727	Methotrexate	ABCB1 protein results in increased susceptibility to [Methotrexate co-treated with Methylprednisolone]	16932953
D008727	Methotrexate	Methotrexate results in increased expression of ABCB1 mRNA	17982279; 24736981;
D008727	Methotrexate	Methotrexate results in increased expression of ABCB1 protein	15239124; 24736981;
D008727	Methotrexate	Vitamin B 12 inhibits the reaction [Methotrexate results in increased expression of ABCB1 mRNA]	17982279
D008727	Methotrexate	ABCB1 protein results in increased transport of Methotrexate	27377006
D008727	Methotrexate	Resveratrol inhibits the reaction [ABCB1 protein results in increased transport of Methotrexate]	27377006
D008730	Methoxsalen	Methoxsalen results in decreased activity of ABCB1 protein	29079042
D008730	Methoxsalen	[Methoxsalen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of Daunorubicin	29079042
D008730	Methoxsalen	Methoxsalen results in increased expression of ABCB1 mRNA	29079042
D008730	Methoxsalen	Verapamil inhibits the reaction [Methoxsalen results in decreased activity of ABCB1 protein]	29079042
D008730	Methoxsalen	Verapamil inhibits the reaction [[Methoxsalen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of Daunorubicin]	29079042
C406712	methoxyfenozide	ABCB1 protein results in increased transport of methoxyfenozide	26995013
C406712	methoxyfenozide	methoxyfenozide inhibits the reaction [ABCB1 protein results in increased transport of Quinidine]	26995013
C439611	methoxy poly(ethylene glycol-co-epsilon-caprolactone)	[methoxy poly(ethylene glycol-co-epsilon-caprolactone) co-treated with tocophersolan co-treated with Resveratrol] results in decreased expression of ABCB1 protein	25392124
D008748	Methylcholanthrene	Methylcholanthrene results in increased expression of ABCB1 mRNA	11096091
C004925	methylmercuric chloride	methylmercuric chloride results in increased expression of ABCB1 mRNA	17083914
C004925	methylmercuric chloride	methylmercuric chloride affects the expression of ABCB1 mRNA	30041384
D008767	Methylmercury Compounds	ABCB1 gene SNP affects the susceptibility to Methylmercury Compounds	24831289
D008743	Methyl Parathion	Methyl Parathion results in increased activity of ABCB1 protein	17490606
D008743	Methyl Parathion	tetramethylrosamine inhibits the reaction [ABCB1 protein results in increased transport of Methyl Parathion]	17490606
D008775	Methylprednisolone	ABCB1 gene polymorphism affects the susceptibility to [Methotrexate co-treated with Methylprednisolone]	16932953
D008775	Methylprednisolone	ABCB1 protein results in increased secretion of Methylprednisolone	22464980
D008775	Methylprednisolone	ABCB1 protein results in increased susceptibility to [Methotrexate co-treated with Methylprednisolone]	16932953
D008775	Methylprednisolone	Elacridar inhibits the reaction [ABCB1 protein results in increased secretion of Methylprednisolone]	22464980
D008775	Methylprednisolone	Methylprednisolone results in increased expression of ABCB1 mRNA	22079615
D008775	Methylprednisolone	Methylprednisolone results in increased expression of ABCB1 protein	22079615; 22464980;
D008775	Methylprednisolone	valspodar inhibits the reaction [ABCB1 protein results in increased secretion of Methylprednisolone]	22464980
C051786	metolachlor	ABCB1 protein affects the reaction [metolachlor results in increased susceptibility to Paclitaxel]	18433974
C051786	metolachlor	metolachlor results in increased activity of ABCB1 protein	18433974
D008801	Mexiletine	ABCB1 mutant form results in increased susceptibility to Mexiletine	16594604
D008825	Miconazole	Miconazole inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]	12235267
D008825	Miconazole	Miconazole inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]	12235267
D008874	Midazolam	Midazolam results in increased expression of ABCB1 protein	8632764
C059539	midostaurin	midostaurin results in decreased activity of ABCB1 protein	11836167
D015735	Mifepristone	ABCB1 protein affects the reaction [Mifepristone results in decreased transport of calcein AM]	30217652
C039128	miltefosine	ABCB1 protein results in decreased susceptibility to miltefosine	11355955
C039128	miltefosine	miltefosine binds to and results in decreased activity of ABCB1 protein	11355955
D000078785	Mirtazapine	ABCB1 protein results in increased export of Mirtazapine	14550684
D016685	Mitomycin	Mitomycin results in increased expression of ABCB1 protein	17934748
D008939	Mitotane	[valspodar results in decreased activity of ABCB1 protein] promotes the reaction [Mitotane results in decreased secretion of Hydrocortisone]	10898547
D008939	Mitotane	Mitotane inhibits the reaction [ABCB1 protein results in increased export of Daunorubicin]	9815696
D008939	Mitotane	Mitotane results in decreased activity of ABCB1 protein	12015757; 1675220;
D008939	Mitotane	Mitotane results in increased expression of ABCB1 mRNA	31312845
D008939	Mitotane	Mitotane results in increased expression of ABCB1 mRNA	25542188
D008939	Mitotane	Mitotane results in increased expression of ABCB1 protein	25542188
D008942	Mitoxantrone	Mitoxantrone results in increased expression of ABCB1 protein	15239124
C001801	mitragynine	mitragynine results in decreased activity of ABCB1 protein	24841968
C070571	ML 7	[ML 7 results in decreased activity of MYLK protein] affects the reaction [ABCB1 protein affects the transport of Digoxin]	20510202
D000068656	Mometasone Furoate	Mometasone Furoate inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	16442095
D000068656	Mometasone Furoate	Mometasone Furoate inhibits the reaction [ABCB1 protein results in increased export of fluorexon]	16442095
D000068656	Mometasone Furoate	Mometasone Furoate inhibits the reaction [ABCB1 results in decreased susceptibility to Daunorubicin]	18310528
D009020	Morphine	ABCB1 affects the metabolism of Morphine	23748253
C027837	moxidectin	ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of ALB mRNA]	25419811
C027837	moxidectin	ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of DAO mRNA]	25419811
C027837	moxidectin	ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of EBF3 mRNA]	25419811
C027837	moxidectin	ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of GABRQ mRNA]	25419811
C027837	moxidectin	ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of GLRA1 mRNA]	25419811
C027837	moxidectin	ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of KLK6 mRNA]	25419811
C027837	moxidectin	ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of MAB21L2 mRNA]	25419811
C027837	moxidectin	ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of SLC10A4 mRNA]	25419811
C027837	moxidectin	ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of SLC18A2 mRNA]	25419811
C027837	moxidectin	ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of TTR mRNA]	25419811
C027837	moxidectin	ABCB1 gene mutant form results in increased susceptibility to moxidectin	25419811
C027837	moxidectin	ABCB1 mutant form results in increased susceptibility to moxidectin	23186803
C027837	moxidectin	moxidectin results in decreased expression of ABCB1 protein	21458446
C420606	mulberroside A	mulberroside A inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 mRNA]	27918128
C420606	mulberroside A	mulberroside A inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 protein]	27918128
C420606	mulberroside A	mulberroside A results in decreased expression of ABCB1 mRNA	24530447
C420606	mulberroside A	mulberroside A results in decreased expression of and results in decreased activity of ABCB1 protein	24530447
C031448	musk ketone	musk ketone results in decreased activity of ABCB1 protein	26929997
C031448	musk ketone	[musk ketone results in decreased activity of ABCB1 protein] which results in decreased export of calcein AM	26929997
C522231	N-(1-phenylcyclohexyl)-3-ethoxypropanamine	N-(1-phenylcyclohexyl)-3-ethoxypropanamine results in increased activity of ABCB1 protein	23273999
C063509	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased expression of ABCB1 mRNA]	12926078
C063509	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased expression of ABCB1 protein	23466342
C080955	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of ABCB1 mRNA	23466342
C080955	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of ABCB1 protein	21745461; 23466342;
C080955	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of ABCB1 mRNA	21745461
C091682	(N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine	Cycloheximide inhibits the reaction [[Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]	18474546
C091682	(N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine	Cycloheximide inhibits the reaction [[Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]	18474546
C091682	(N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine	Dactinomycin inhibits the reaction [[Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]	18474546
C091682	(N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine	Dactinomycin inhibits the reaction [[Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]	18474546
C091682	(N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine	[Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine	18474546
C091682	(N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine	[Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine	18474546
C037974	N-(7-(4-nitrobenzo-2-oxa-1,3-diazole))-6-aminocaproyl sphingosine	ABCB1 protein results in increased transport of N-(7-(4-nitrobenzo-2-oxa-1,3-diazole))-6-aminocaproyl sphingosine	21436125
C064769	N-acetylsphingosine	N-acetylsphingosine results in increased expression of ABCB1	11573427
D009270	Naloxone	Naloxone results in increased expression of ABCB1 mRNA	17522070
D037742	Nanotubes, Carbon	MYC protein inhibits the reaction [Nanotubes, Carbon results in decreased expression of ABCB1 protein]	25461681
D037742	Nanotubes, Carbon	Nanotubes, Carbon results in decreased expression of and results in decreased activity of ABCB1 protein	25461681
C031721	naphthalene	naphthalene results in decreased activity of ABCB1 protein	19135510
C542131	naphthalenediimide	naphthalenediimide analog results in decreased expression of ABCB1 mRNA	30840857
D009288	Naproxen	Naproxen affects the expression of ABCB1 mRNA	18581209
C005273	naringenin	naringenin results in increased expression of ABCB1 mRNA	19148864
C101954	N-caproylsphingosine	ABCB1 protein results in decreased susceptibility to N-caproylsphingosine	21436125
C101954	N-caproylsphingosine	valspodar inhibits the reaction [ABCB1 protein results in decreased susceptibility to N-caproylsphingosine]	21436125
C524509	N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide	ABCB1 protein affects the abundance of N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide	24321342
C524509	N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide	ABCB1 protein results in increased transport of N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide	24321342
C524509	N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide	N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide binds to and results in decreased activity of ABCB1 protein	24321342
C524509	N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide	N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	24321342
C524509	N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide	[Verapamil binds to and results in decreased activity of ABCB1 protein] which results in decreased transport of N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide	24321342
C524509	N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide]	24321342
C524509	N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide	[zosuquidar trihydrochloride results in decreased activity of ABCB1 protein] which results in decreased transport of N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide	24321342
D019888	Nelfinavir	ABCB1 gene SNP affects the susceptibility to Nelfinavir	16041239
D019888	Nelfinavir	ABCB1 intron SNP affects the susceptibility to Nelfinavir	16041239
D019888	Nelfinavir	ABCB1 protein affects the transport of Nelfinavir	16041239
C056041	nemadectin	nemadectin results in decreased expression of ABCB1 mRNA	20487225
C056041	nemadectin	nemadectin results in decreased expression of ABCB1 protein	20487225
D009529	Nicardipine	Nicardipine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
D009532	Nickel	Nickel inhibits the reaction [Magnesium results in increased activity of ABCB1 protein]	2900677
D009532	Nickel	Nickel results in decreased expression of ABCB1 mRNA	25583101
C022838	nickel chloride	ABCB1 protein results in decreased susceptibility to nickel chloride	24448832
C022838	nickel chloride	alpha-Tocopherol inhibits the reaction [nickel chloride results in increased expression of ABCB1 protein]	24448832
C022838	nickel chloride	fumonisin B1 inhibits the reaction [nickel chloride results in increased expression of ABCB1 protein]	24448832
C022838	nickel chloride	nickel chloride results in increased expression of ABCB1 mRNA	24448832
C022838	nickel chloride	nickel chloride results in increased expression of ABCB1 protein	24448832
D009543	Nifedipine	Nifedipine results in increased expression of ABCB1 protein	8632764
D009544	Niflumic Acid	Niflumic Acid inhibits the reaction [[avermectin results in increased abundance of Calcium] which results in increased expression of ABCB1 protein]	23523950
D009544	Niflumic Acid	Niflumic Acid results in decreased expression of ABCB1 protein	23523950
C035100	nilvadipine	nilvadipine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
C012655	nimesulide	nimesulide results in decreased expression of ABCB1 protein	21745461
C012655	nimesulide	nimesulide results in increased expression of ABCB1 mRNA	21745461
D015737	Nisoldipine	Nisoldipine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	11895100
D018817	N-Methyl-3,4-methylenedioxyamphetamine	N-Methyl-3,4-methylenedioxyamphetamine results in decreased activity of ABCB1 protein	14690877
C009074	N-n-propylnorapomorphine	Clozapine inhibits the reaction [N-n-propylnorapomorphine results in increased expression of ABCB1 protein]	9111066
C009074	N-n-propylnorapomorphine	N-n-propylnorapomorphine results in increased expression of ABCB1 protein	9111066
C009074	N-n-propylnorapomorphine	Spiperone inhibits the reaction [N-n-propylnorapomorphine results in increased expression of ABCB1 protein]	9111066
C008661	nobiletin	nobiletin promotes the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]	18955043
C008661	nobiletin	nobiletin promotes the reaction [ABCB1 protein results in increased import of Daunorubicin]	18955043
C069053	norathyriol	norathyriol results in increased expression of ABCB1 protein	20513373
D009640	Norethindrone	Norethindrone results in increased expression of ABCB1 mRNA	15290871
D009661	Nortriptyline	ABCB1 exon SNP affects the susceptibility to Nortriptyline	12082591
C072936	notoginsenoside R1	notoginsenoside R1 results in increased expression of ABCB1 mRNA	25472953
C072936	notoginsenoside R1	NR1I2 protein promotes the reaction [notoginsenoside R1 results in increased expression of ABCB1 mRNA]	25472953
C511311	NSC73306	ABCB1 protein results in increased susceptibility to NSC73306	21721528
C511311	NSC73306	tariquidar inhibits the reaction [ABCB1 protein results in increased susceptibility to NSC73306]	21721528
C511311	NSC73306	valspodar inhibits the reaction [ABCB1 protein results in increased susceptibility to NSC73306]	21721528
C511311	NSC73306	zosuquidar trihydrochloride analog inhibits the reaction [ABCB1 protein results in increased susceptibility to NSC73306]	21721528
C511311	NSC73306	ABCB1 protein results in increased susceptibility to NSC73306	24800945
C511311	NSC73306	Cisplatin inhibits the reaction [ABCB1 protein results in increased susceptibility to NSC73306]	24800945
C511311	NSC73306	ABCB1 protein results in increased susceptibility to NSC73306	21657271
C553194	NVP-BSK805	NVP-BSK805 results in decreased activity of ABCB1 protein	28669723
C064976	O(6)-benzylguanine	[MGMT protein mutant form co-treated with ABCB1 protein] results in decreased susceptibility to [Carmustine co-treated with O(6)-benzylguanine]	16733832
C410029	OC 144-093	OC 144-093 results in decreased activity of ABCB1 protein	11808870
D009822	Oils, Volatile	Oils, Volatile results in increased expression of ABCB1 mRNA	30071242
D019319	Okadaic Acid	ABCB1 protein results in increased transport of Okadaic Acid	24374049
D000077152	Olanzapine	Olanzapine results in decreased activity of ABCB1 protein	16810505
C026209	oltipraz	oltipraz results in increased expression of ABCB1 mRNA	16837569
C000591640	omadacycline	ABCB1 protein results in increased transport of omadacycline	27499331
C000591640	omadacycline	[zosuquidar trihydrochloride results in decreased activity of ABCB1 protein] which results in decreased transport of omadacycline	27499331
D009853	Omeprazole	Omeprazole promotes the reaction [Cisplatin results in increased expression of ABCB1 protein]	30452898
D009853	Omeprazole	Omeprazole binds to ABCB1 protein	10783826
D009853	Omeprazole	Omeprazole metabolite binds to ABCB1 protein	10783826
C009618	O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate	O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate results in increased expression of ABCB1 mRNA	15130596
C016340	o,p'-DDT	o,p'-DDT results in decreased activity of ABCB1 protein	23169446
C016340	o,p'-DDT	o,p'-DDT results in increased expression of ABCB1 mRNA	24464585
C040764	ophiobolin A	ophiobolin A inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D009943	Organophosphorus Compounds	ABCB1 gene SNP affects the susceptibility to Organophosphorus Compounds	26457621
D010042	Ouabain	2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [Ouabain results in increased expression of ABCB1 protein]	19647009
D010042	Ouabain	3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Ouabain results in increased expression of ABCB1 mRNA]	19647009
D010042	Ouabain	3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Ouabain results in increased expression of ABCB1 protein]	19647009
D010042	Ouabain	KN 93 inhibits the reaction [Ouabain results in increased expression of ABCB1 protein]	19647009
D010042	Ouabain	Ouabain results in increased expression of ABCB1 mRNA	19647009
D010042	Ouabain	Ouabain results in increased expression of ABCB1 protein	19647009
D010042	Ouabain	[Ouabain results in increased expression of ABCB1] which results in decreased susceptibility to Doxorubicin	19647009
C005290	oxybenzone	oxybenzone results in increased activity of ABCB1 protein	23690080
D010100	Oxygen	Oxygen deficiency results in decreased expression of ABCB1 mRNA	19695866
D010100	Oxygen	Oxygen deficiency results in increased expression of ABCB1 mRNA	15604272
D010100	Oxygen	pyrazolanthrone inhibits the reaction [Oxygen deficiency results in increased expression of ABCB1 mRNA]	15604272
D010100	Oxygen	Oxygen deficiency results in increased expression of ABCB1 protein	15604272
D010126	Ozone	Ozone results in increased expression of ABCB1 mRNA	16330353
D017239	Paclitaxel	6-OH-BDE-47 inhibits the reaction [ABCB1 protein results in increased export of Paclitaxel]	28031414
D017239	Paclitaxel	ABCB1 gene polymorphism affects the metabolism of Paclitaxel	15901749
D017239	Paclitaxel	ABCB1 gene SNP affects the susceptibility to Paclitaxel	16950614
D017239	Paclitaxel	ABCB1 mRNA results in decreased susceptibility to Paclitaxel	16322897
D017239	Paclitaxel	ABCB1 mRNA results in increased susceptibility to Paclitaxel	15239142
D017239	Paclitaxel	ABCB1 protein affects the reaction [acetochlor results in increased susceptibility to Paclitaxel]	18433974
D017239	Paclitaxel	ABCB1 protein affects the reaction [alachlor results in increased susceptibility to Paclitaxel]	18433974
D017239	Paclitaxel	ABCB1 protein affects the reaction [metolachlor results in increased susceptibility to Paclitaxel]	18433974
D017239	Paclitaxel	ABCB1 protein results in decreased susceptibility to Paclitaxel	15252144; 15990222; 16831368; 17284363; 17697605; 20196146; 22233293; 22792399; 25058526; 25268938; 26689174; 27664577; 29625142;
D017239	Paclitaxel	ABCB1 protein results in decreased uptake of Paclitaxel	10617675
D017239	Paclitaxel	ABCB1 protein results in increased export of and affects the susceptibility to Paclitaxel	18433974
D017239	Paclitaxel	ABCB1 protein results in increased export of Paclitaxel	28031414
D017239	Paclitaxel	ABCB1 protein results in increased transport of Paclitaxel	12708479
D017239	Paclitaxel	Carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Paclitaxel]	12708479
D017239	Paclitaxel	[Carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Paclitaxel]] which results in decreased susceptibility to Paclitaxel	12708479
D017239	Paclitaxel	CEP 33779 inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	25058526
D017239	Paclitaxel	cinchonine analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	20196146
D017239	Paclitaxel	cinchonine inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	20196146
D017239	Paclitaxel	Crizotinib inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	22233293
D017239	Paclitaxel	Curcumin analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	26689174
D017239	Paclitaxel	Curcumin inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	26689174
D017239	Paclitaxel	[CXCL8 results in increased expression of ABCB1 mRNA] which results in decreased susceptibility to Paclitaxel	21742513
D017239	Paclitaxel	[CXCL8 results in increased expression of ABCB1 protein] which results in decreased susceptibility to Paclitaxel	21742513
D017239	Paclitaxel	[Cyclosporine results in decreased activity of ABCB1 protein] which results in increased susceptibility to Paclitaxel	18673531
D017239	Paclitaxel	HIF1A protein affects the reaction [[Paclitaxel co-treated with IL6 protein] results in increased expression of ABCB1 protein]	29341321
D017239	Paclitaxel	Ketoconazole inhibits the reaction [Paclitaxel results in increased expression of ABCB1 mRNA]	16819505
D017239	Paclitaxel	Ketoconazole inhibits the reaction [Paclitaxel results in increased expression of ABCB1 protein]	16819505
D017239	Paclitaxel	NR1I2 protein promotes the reaction [Paclitaxel results in increased expression of and results in increased activity of ABCB1 protein]	20041327
D017239	Paclitaxel	[Paclitaxel co-treated with IL6 protein] results in increased expression of ABCB1 protein	29341321
D017239	Paclitaxel	Paclitaxel results in increased activity of ABCB1 protein	14512701
D017239	Paclitaxel	[Paclitaxel results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA	20041327
D017239	Paclitaxel	Paclitaxel results in increased expression of ABCB1 mRNA	15650019; 16819505; 17284363; 21833476;
D017239	Paclitaxel	Paclitaxel results in increased expression of ABCB1 protein	15650019; 15990222; 16819505; 17284363; 20041327; 21833476; 23707768;
D017239	Paclitaxel	[Paclitaxel results in increased expression of ABCB1] which results in decreased susceptibility to Cisplatin	21833476
D017239	Paclitaxel	[Paclitaxel results in increased expression of ABCB1] which results in decreased susceptibility to Doxorubicin	21833476
D017239	Paclitaxel	[Paclitaxel results in increased expression of ABCB1] which results in decreased susceptibility to Fluorouracil	21833476
D017239	Paclitaxel	[Paclitaxel results in increased expression of ABCB1] which results in decreased susceptibility to Vincristine	21833476
D017239	Paclitaxel	Paclitaxel results in increased expression of and binds to and results in increased activity of ABCB1 protein	29625142
D017239	Paclitaxel	propiconazole inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	25268938
D017239	Paclitaxel	Quinidine inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	20196146
D017239	Paclitaxel	[Tiopronin results in decreased expression of ABCB1 protein] which results in increased susceptibility to Paclitaxel	21657271
D017239	Paclitaxel	[valspodar results in decreased activity of ABCB1 protein] which results in increased susceptibility to Paclitaxel	18673531
D017239	Paclitaxel	Verapamil inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	22233293; 25058526;
D017239	Paclitaxel	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Paclitaxel]	12708479
D017239	Paclitaxel	[Verapamil results in decreased activity of ABCB1 protein] which results in increased susceptibility to Paclitaxel	18673531
D017239	Paclitaxel	ABCB1 results in decreased susceptibility to Paclitaxel	10430060
D000068882	Paliperidone Palmitate	ABCB1 gene polymorphism affects the abundance of Paliperidone Palmitate	17541883
D000068882	Paliperidone Palmitate	ABCB1 protein affects the abundance of Paliperidone Palmitate	17541883
D000068882	Paliperidone Palmitate	ABCB1 protein results in increased transport of Paliperidone Palmitate	22691713
D000068882	Paliperidone Palmitate	Paliperidone Palmitate inhibits the reaction [ABCB1 protein results in decreased export of Doxorubicin]	16936711
D000068882	Paliperidone Palmitate	Paliperidone Palmitate results in decreased activity of ABCB1 protein	16810505; 16936711;
D010269	Paraquat	ABCB1 protein affects the reaction [Doxorubicin results in decreased susceptibility to Paraquat]	23220037
D010269	Paraquat	ABCB1 protein results in increased export of and results in decreased susceptibility to Paraquat	25015657
D010269	Paraquat	[Doxorubicin results in increased expression of ABCB1 protein] which results in decreased susceptibility to Paraquat	23220037
D010269	Paraquat	valspodar inhibits the reaction [ABCB1 protein results in increased export of Paraquat]	25015657
D010278	Parathion	ABCB1 protein results in decreased export of Parathion	8917702
D010278	Parathion	Parathion binds to ABCB1 protein	8917702
D010278	Parathion	Parathion inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	8917702
D017374	Paroxetine	ABCB1 protein results in increased export of Paroxetine	14550684
D052638	Particulate Matter	acetovanillone inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D052638	Particulate Matter	Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D052638	Particulate Matter	CAT protein inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D052638	Particulate Matter	Cycloheximide inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D052638	Particulate Matter	Cycloheximide inhibits the reaction [[Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]	18474546
D052638	Particulate Matter	Dactinomycin inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D052638	Particulate Matter	Dactinomycin inhibits the reaction [[Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]	18474546
D052638	Particulate Matter	diphenyleneiodonium inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D052638	Particulate Matter	Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein	18474546
D052638	Particulate Matter	[Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine	18474546
D052638	Particulate Matter	pyrazolanthrone inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D052638	Particulate Matter	TIMP3 protein inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D052638	Particulate Matter	TNF protein affects the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D052638	Particulate Matter	TNFRSF1A protein affects the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]	18474546
C513937	PB28 compound	PB28 compound results in decreased expression of ABCB1 protein	16891467
C513937	PB28 compound	PB28 compound results in decreased activity of ABCB1 protein	21229979
C086401	pentabromodiphenyl ether	pentabromodiphenyl ether results in decreased expression of ABCB1 mRNA	23948077
D010416	Pentachlorophenol	Pentachlorophenol results in increased expression of ABCB1 mRNA	24486881
D010416	Pentachlorophenol	Pentachlorophenol results in decreased activity of ABCB1 protein	26929997
D010416	Pentachlorophenol	[Pentachlorophenol results in decreased activity of ABCB1 protein] which results in decreased export of calcein AM	26929997
C015424	peppermint oil	peppermint oil results in increased expression of ABCB1 mRNA	30071242
C076994	perfluorooctane sulfonic acid	perfluorooctane sulfonic acid results in decreased activity of ABCB1 protein	24014645
C023036	perfluorooctanoic acid	perfluorooctanoic acid results in decreased activity of ABCB1 protein	24014645
D010575	Pesticides	ABCB1 gene SNP affects the susceptibility to Pesticides	26457621
D010590	Phalloidine	Phalloidine results in decreased localization of ABCB1 protein	12169763
D010634	Phenobarbital	Phenobarbital affects the expression of ABCB1 mRNA	19159669
D010634	Phenobarbital	Phenobarbital results in decreased activity of ABCB1 protein	18408562
D010634	Phenobarbital	Phenobarbital results in increased expression of ABCB1 mRNA	16837569; 18094037; 19084549; 19409404; 22258563;
D010634	Phenobarbital	Phenobarbital results in increased expression of ABCB1 protein	16837569; 8632764;
D010634	Phenobarbital	ABCB1 protein results in increased export of Phenobarbital	18063342
D010634	Phenobarbital	Amino Acids, Peptides, and Proteins inhibits the reaction [Phenobarbital results in increased expression of ABCB1 protein]	18473823
D010634	Phenobarbital	Phenobarbital results in decreased expression of ABCB1 mRNA	20607812
D010634	Phenobarbital	Phenobarbital results in increased expression of ABCB1 protein	15569486; 18473823;
D010636	Phenols	ABCB1 gene SNP results in increased susceptibility to Phenols analog	23874772
D010654	Phenylbutyrates	[Tretinoin co-treated with Phenylbutyrates co-treated with 1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene] results in increased expression of ABCB1 protein	23284745
D010672	Phenytoin	ABCB1 protein affects the abundance of Phenytoin	10580886; 8001500;
D010672	Phenytoin	ABCB1 protein affects the susceptibility to Phenytoin	14749549; 17376120; 17529887;
D010672	Phenytoin	ABCB1 protein results in increased metabolism of Phenytoin	16220110
D010672	Phenytoin	Phenytoin results in decreased activity of ABCB1 protein	18408562
D010672	Phenytoin	Amino Acids, Peptides, and Proteins inhibits the reaction [Phenytoin results in increased expression of ABCB1 protein]	18473823
D010672	Phenytoin	Phenytoin results in increased expression of ABCB1 protein	15569486; 18473823;
C085059	phloxine	phloxine results in decreased activity of ABCB1 protein	20041016
C003117	phosalone	Diazinon promotes the reaction [phosalone inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C003117	phosalone	Diazinon promotes the reaction [phosalone results in decreased activity of ABCB1 protein]	21783720
C003117	phosalone	Endosulfan inhibits the reaction [phosalone inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C003117	phosalone	Endosulfan inhibits the reaction [phosalone results in decreased activity of ABCB1 protein]	21783720
C003117	phosalone	[phosalone co-treated with Verapamil] inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
C003117	phosalone	[phosalone co-treated with Verapamil] results in decreased activity of ABCB1 protein	21783720
C003117	phosalone	phosalone inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
C003117	phosalone	phosalone inhibits the reaction [Endosulfan inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C003117	phosalone	phosalone inhibits the reaction [Endosulfan results in decreased activity of ABCB1 protein]	21783720
C003117	phosalone	phosalone inhibits the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C003117	phosalone	phosalone inhibits the reaction [propiconazole results in decreased activity of ABCB1 protein]	21783720
C003117	phosalone	phosalone results in decreased activity of ABCB1 protein	21783720
C003117	phosalone	propiconazole inhibits the reaction [phosalone inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C003117	phosalone	propiconazole inhibits the reaction [phosalone results in decreased activity of ABCB1 protein]	21783720
D010713	Phosphatidylcholines	ABCB1 protein affects the export of Phosphatidylcholines	11147995
D010713	Phosphatidylcholines	ABCB1 protein affects the transport of Phosphatidylcholines	11745043
D010720	Phosphines	ABCB1 protein results in increased transport of Phosphines	9369495
C030090	phosphoramide mustard	phosphoramide mustard results in decreased expression of ABCB1 protein	27888070
D010795	Phthalic Acids	ABCB1 gene SNP results in increased susceptibility to Phthalic Acids	23874772
D010798	Phycocyanin	Phycocyanin inhibits the reaction [2-Acetylaminofluorene results in increased expression of ABCB1 mRNA]	17303067
D010798	Phycocyanin	Phycocyanin inhibits the reaction [2-Acetylaminofluorene results in increased expression of ABCB1 protein]	17303067
C522973	PI103	PI103 results in decreased expression of ABCB1 mRNA	23300809
C117268	pimecrolimus	pimecrolimus inhibits the reaction [Rifampin results in increased expression of ABCB1 mRNA]	29356861
D000077205	Pioglitazone	Pioglitazone results in increased expression of ABCB1 mRNA	31233785
C008922	piperine	Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 mRNA]]	23707768
C008922	piperine	Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 protein]]	23707768
C008922	piperine	NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 mRNA]	23707768
C008922	piperine	NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 protein]	23707768
C008922	piperine	piperine results in increased expression of ABCB1 mRNA	23707768
C008922	piperine	piperine results in increased expression of ABCB1 protein	23707768
C006253	pirinixic acid	[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ABCB1 mRNA	19710929
C108475	pitavastatin	ABCB1 protein affects the transport of pitavastatin	15955871
D010936	Plant Extracts	Plant Extracts affects the reaction [ABCB1 protein results in increased transport of Cyclosporine]	12545142
D010936	Plant Extracts	Plant Extracts promotes the reaction [ABCB1 protein results in increased transport of fexofenadine]	12545142
D010936	Plant Extracts	Plant Extracts results in decreased activity of ABCB1 protein	15627040; 15890377; 18425719;
D010936	Plant Extracts	[Plant Extracts results in decreased activity of ABCB1 protein] which results in decreased export of Digoxin	15890377
D010936	Plant Extracts	Plant Extracts results in increased activity of ABCB1 protein	12545142; 24446304;
D010936	Plant Extracts	Plant Extracts results in increased expression of ABCB1 mRNA	18439772
D010936	Plant Extracts	Plant Extracts results in increased expression of and results in increased activity of ABCB1 protein	18439772
D010936	Plant Extracts	Plant Extracts results in increased activity of ABCB1 protein	16033948
D028321	Plant Preparations	Plant Preparations analog results in increased expression of ABCB1 mRNA	19148864
D028321	Plant Preparations	Plant Preparations results in increased expression of ABCB1 mRNA	18047722
C013649	plastochromanol 8	plastochromanol 8 results in increased expression of ABCB1	15269186
C422648	pluronic block copolymer p85	pluronic block copolymer p85 inhibits the reaction [Doxorubicin results in increased expression of ABCB1 protein]	16579640
C422648	pluronic block copolymer p85	pluronic block copolymer p85 results in decreased folding of and results in decreased activity of ABCB1 protein	15648254
D011090	Polyenes	Polyenes results in decreased activity of ABCB1 protein	18425719
C057532	polyisohexylcyanoacrylate	[Doxorubicin co-treated with polyisohexylcyanoacrylate] results in increased expression of ABCB1 mRNA	15826724
D053279	Polyynes	Polyynes results in decreased activity of ABCB1 protein	18425719
D011192	Potassium Dichromate	Potassium Dichromate results in increased activity of ABCB1 protein	22580103
D017035	Pravastatin	ABCB1 protein results in increased transport of Pravastatin	15616150
D017035	Pravastatin	ABCB1 protein results in increased transport of Pravastatin analog	15616150
D011224	Prazosin	ABCB1 protein affects the transport of Prazosin	15616150
D011239	Prednisolone	ABCB1 results in decreased susceptibility to Prednisolone	18310528
D011241	Prednisone	ABCB1 protein results in increased secretion of Prednisone	22464980
D011241	Prednisone	Elacridar inhibits the reaction [ABCB1 protein results in increased secretion of Prednisone]	22464980
D011241	Prednisone	valspodar inhibits the reaction [ABCB1 protein results in increased secretion of Prednisone]	22464980
D011285	Pregnenolone Carbonitrile	Pregnenolone Carbonitrile results in increased expression of ABCB1 mRNA	15914091
D011285	Pregnenolone Carbonitrile	Ketoconazole inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCB1 mRNA]	16819505
D011285	Pregnenolone Carbonitrile	Ketoconazole inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCB1 protein]	16819505
D011285	Pregnenolone Carbonitrile	NR1I2 gene mutant form inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCB1 mRNA]	16819505
D011285	Pregnenolone Carbonitrile	NR1I2 gene mutant form inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCB1 protein]	16819505
D011285	Pregnenolone Carbonitrile	Pregnenolone Carbonitrile results in increased expression of ABCB1 mRNA	16819505
D011285	Pregnenolone Carbonitrile	Pregnenolone Carbonitrile results in increased expression of ABCB1 protein	16819505
C045362	prochloraz	prochloraz results in increased expression of ABCB1 protein	27028005
C045362	prochloraz	prochloraz results in decreased activity of ABCB1 protein	11408081
D011374	Progesterone	Dactinomycin inhibits the reaction [Progesterone results in increased expression of ABCB1 mRNA]	19813763
D011374	Progesterone	Dactinomycin inhibits the reaction [Progesterone results in increased expression of ABCB1 protein]	19813763
D011374	Progesterone	Progesterone results in increased expression of ABCB1 mRNA	15290871; 19813763;
D011374	Progesterone	Progesterone results in increased expression of ABCB1 protein	19813763
D011372	Progestins	Progestins results in increased expression of ABCB1 mRNA	19609016
C045950	propiconazole	Diazinon promotes the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C045950	propiconazole	Diazinon promotes the reaction [propiconazole results in decreased activity of ABCB1 protein]	21783720
C045950	propiconazole	Endosulfan promotes the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C045950	propiconazole	Endosulfan promotes the reaction [propiconazole results in decreased activity of ABCB1 protein]	21783720
C045950	propiconazole	phosalone inhibits the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C045950	propiconazole	phosalone inhibits the reaction [propiconazole results in decreased activity of ABCB1 protein]	21783720
C045950	propiconazole	propiconazole inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	25268938
C045950	propiconazole	propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
C045950	propiconazole	propiconazole inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	25268938
C045950	propiconazole	propiconazole inhibits the reaction [phosalone inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C045950	propiconazole	propiconazole inhibits the reaction [phosalone results in decreased activity of ABCB1 protein]	21783720
C045950	propiconazole	propiconazole metabolite affects the reaction [ABCB1 protein results in increased transport of quinidinium]	25268938
C045950	propiconazole	propiconazole promotes the reaction [Endosulfan inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C045950	propiconazole	propiconazole promotes the reaction [Endosulfan results in decreased activity of ABCB1 protein]	21783720
C045950	propiconazole	propiconazole promotes the reaction [Verapamil inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C045950	propiconazole	propiconazole promotes the reaction [Verapamil results in decreased activity of ABCB1 protein]	21783720
C045950	propiconazole	propiconazole results in decreased activity of ABCB1 protein	21783720
C045950	propiconazole	propiconazole results in increased expression of ABCB1 mRNA	19409404
C045950	propiconazole	Verapamil promotes the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
C045950	propiconazole	Verapamil promotes the reaction [propiconazole results in decreased activity of ABCB1 protein]	21783720
D011433	Propranolol	Propranolol results in increased expression of ABCB1 mRNA	22559005
D011433	Propranolol	Propranolol inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	16671962
D011433	Propranolol	Propranolol results in increased expression of ABCB1 mRNA	15276086
D011442	Proscillaridin	ABCB1 protein results in increased transport of Proscillaridin	26708294
D011442	Proscillaridin	Proscillaridin inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	23104431
C074191	prulifloxacin	ABCB1 protein affects the transport of prulifloxacin metabolite	15618759
C025543	psorospermin	psorospermin inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	7083125
D011691	Puromycin	ABCB1 protein results in increased transport of Puromycin	20018165
C432165	pyrazolanthrone	pyrazolanthrone inhibits the reaction [MAP3K1 protein results in increased expression of ABCB1 mRNA]	15604272
C432165	pyrazolanthrone	pyrazolanthrone inhibits the reaction [Oxygen deficiency results in increased expression of ABCB1 mRNA]	15604272
C432165	pyrazolanthrone	pyrazolanthrone inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]	18474546
C432165	pyrazolanthrone	pyrazolanthrone inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]	18474546
C020972	pyrrolidine dithiocarbamic acid	pyrrolidine dithiocarbamic acid inhibits the reaction [avermectin results in increased expression of ABCB1 protein]	23523950
C020972	pyrrolidine dithiocarbamic acid	pyrrolidine dithiocarbamic acid inhibits the reaction [Cadmium Chloride results in increased expression of ABCB1]	10636889
D011794	Quercetin	Quercetin inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir]	15266218
D011794	Quercetin	ABCB1 protein results in decreased abundance of Quercetin	15112361
D011794	Quercetin	[ABCB1 protein results in decreased susceptibility to Doxorubicin] inhibits the reaction [Quercetin results in increased cleavage of PARP1 protein]	20438634
D011794	Quercetin	ABCB1 protein results in increased transport of Quercetin	15969930
D011794	Quercetin	[Quercetin co-treated with Doxorubicin] results in decreased expression of ABCB1 protein	25339540
D011794	Quercetin	Quercetin inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]	20438634; 20438634;
D011794	Quercetin	Quercetin inhibits the reaction [Doxorubicin results in increased expression of ABCB1 mRNA]	25687049
D011794	Quercetin	Quercetin results in decreased expression of ABCB1	16059641; 20335952;
D011794	Quercetin	Quercetin results in decreased expression of ABCB1 mRNA	18283591; 18624906; 21632981;
D011794	Quercetin	Quercetin results in decreased expression of ABCB1 protein	18283591; 18624906; 20513373; 25339540;
D011794	Quercetin	Quercetin results in increased expression of ABCB1 mRNA	15266218; 26238175; 26366751;
D011794	Quercetin	Quercetin results in increased expression of ABCB1 protein	26366751
D011794	Quercetin	VDR promotes the reaction [Quercetin results in increased expression of ABCB1 mRNA]	26366751
D011794	Quercetin	Verapamil inhibits the reaction [ABCB1 protein results in decreased abundance of Quercetin]	15112361
D000069348	Quetiapine Fumarate	Quetiapine Fumarate results in decreased activity of ABCB1 protein	16810505
D011796	Quinacrine	ABCB1 protein results in increased transport of Quinacrine	16581945
D011796	Quinacrine	Elacridar inhibits the reaction [ABCB1 protein results in increased transport of Quinacrine]	16581945
D011802	Quinidine	Quinidine results in decreased activity of ABCB1 protein	15666293
D011802	Quinidine	Quinidine inhibits the reaction [ABCB1 protein results in decreased susceptibility to thiodicarb]	8898877
D011802	Quinidine	Quinidine inhibits the reaction [ABCB1 protein results in increased export of and results in decreased susceptibility to thiodicarb]	8644124
D011802	Quinidine	Quinidine results in decreased activity of ABCB1 protein	8898877
D011802	Quinidine	ABCB1 protein affects the transport of Quinidine	15616150
D011802	Quinidine	ABCB1 protein results in increased transport of Quinidine	23976943; 26995013;
D011802	Quinidine	methoxyfenozide inhibits the reaction [ABCB1 protein results in increased transport of Quinidine]	26995013
D011802	Quinidine	Quinidine binds to ABCB1 protein	23976943
D011802	Quinidine	Quinidine inhibits the reaction [ABCB1 protein results in decreased susceptibility to Docetaxel]	20196146
D011802	Quinidine	Quinidine inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	20196146
D011802	Quinidine	Quinidine results in decreased expression of ABCB1 protein	20196146
D011802	Quinidine	tebufenozide inhibits the reaction [ABCB1 protein results in increased transport of Quinidine]	26995013
D011802	Quinidine	Quinidine binds to ABCB1 protein	19053318; 7808368;
D011802	Quinidine	Quinidine results in decreased activity of ABCB1 protein	15089813
C454102	quinidinium	ABCB1 protein affects the uptake of quinidinium	11934808
C454102	quinidinium	ABCB1 protein results in increased transport of quinidinium	23104431; 25268938; 31348918;
C454102	quinidinium	bufalin inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	23104431
C454102	quinidinium	cannogenin thevetoside inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	23104431
C454102	quinidinium	Cardenolides inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	23104431
C454102	quinidinium	Cymarine inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	23104431
C454102	quinidinium	Digitoxin inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	23104431
C454102	quinidinium	Digoxin inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	23104431
C454102	quinidinium	Erythromycin inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	25268938
C454102	quinidinium	propiconazole inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	25268938
C454102	quinidinium	propiconazole metabolite affects the reaction [ABCB1 protein results in increased transport of quinidinium]	25268938
C454102	quinidinium	Proscillaridin inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	23104431
C454102	quinidinium	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	25268938; 31348918;
D011803	Quinine	ABCB1 protein affects the uptake of Quinine analog	11934808
D019257	Quinpirole	Clozapine inhibits the reaction [Quinpirole results in increased expression of ABCB1 protein]	9111066
D019257	Quinpirole	Quinpirole results in increased expression of ABCB1 protein	9111066
D019257	Quinpirole	Spiperone inhibits the reaction [Quinpirole results in increased expression of ABCB1 protein]	9111066
D020849	Raloxifene Hydrochloride	ABCB1 protein affects the activity of Raloxifene Hydrochloride	16959878
D020849	Raloxifene Hydrochloride	[Cyclosporine co-treated with Raloxifene Hydrochloride] results in decreased expression of ABCB1 mRNA	17096884
D020849	Raloxifene Hydrochloride	[Cyclosporine co-treated with Raloxifene Hydrochloride] results in decreased expression of ABCB1 protein	17096884
D020849	Raloxifene Hydrochloride	Raloxifene Hydrochloride results in decreased expression of ABCB1 mRNA	17096884
D020849	Raloxifene Hydrochloride	Raloxifene Hydrochloride results in decreased expression of ABCB1 protein	17096884
D011929	Razoxane	ferric nitrilotriacetate inhibits the reaction [Razoxane results in increased expression of ABCB1 protein]	18385176
D011929	Razoxane	Razoxane results in increased expression of ABCB1 protein	18385176
C084826	rescinnamine	rescinnamine results in increased expression of ABCB1 mRNA	7476894
D012110	Reserpine	Cycloheximide promotes the reaction [Reserpine results in increased expression of ABCB1 mRNA]	7476894
D012110	Reserpine	Reserpine inhibits the reaction [ABCB1 protein affects the export of calcein AM]	10617675
D012110	Reserpine	Reserpine inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]	12235267
D012110	Reserpine	Reserpine inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]	12235267
D012110	Reserpine	Reserpine results in decreased activity of ABCB1 protein	19528478
D012110	Reserpine	Reserpine results in increased expression of ABCB1 mRNA	7476894
D012110	Reserpine	Reserpine results in increased expression of ABCB1 protein	8632764
D012110	Reserpine	Reserpine binds to ABCB1 protein	7808368
D000077185	Resveratrol	[Lipopolysaccharides co-treated with Resveratrol] results in decreased expression of ABCB1 mRNA	26667767
D000077185	Resveratrol	[methoxy poly(ethylene glycol-co-epsilon-caprolactone) co-treated with tocophersolan co-treated with Resveratrol] results in decreased expression of ABCB1 protein	25392124
D000077185	Resveratrol	[Resveratrol co-treated with Doxorubicin] results in decreased expression of ABCB1 mRNA	24161697
D000077185	Resveratrol	[[Resveratrol co-treated with Doxorubicin] results in decreased expression of ABCB1 mRNA] which results in increased uptake of Doxorubicin	24161697
D000077185	Resveratrol	Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 mRNA]	19047049
D000077185	Resveratrol	Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein]	19047049
D000077185	Resveratrol	Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 mRNA]	19047049
D000077185	Resveratrol	Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein]	19047049
D000077185	Resveratrol	Resveratrol inhibits the reaction [Rifampin results in increased expression of ABCB1 protein]	26394120
D000077185	Resveratrol	Resveratrol results in decreased expression of ABCB1	19828106
D000077185	Resveratrol	Resveratrol results in decreased expression of ABCB1 mRNA	19484992; 26394120;
D000077185	Resveratrol	Resveratrol results in decreased expression of ABCB1 protein	26394120
D000077185	Resveratrol	Resveratrol results in increased expression of ABCB1 mRNA	18634814
D000077185	Resveratrol	Resveratrol results in increased expression of ABCB1 protein	18634814
D000077185	Resveratrol	[Resveratrol results in increased susceptibility to Doxorubicin] which results in decreased expression of ABCB1 mRNA	24926353
D000077185	Resveratrol	[Resveratrol results in increased susceptibility to Doxorubicin] which results in decreased expression of ABCB1 protein	24926353
D000077185	Resveratrol	Resveratrol results in decreased expression of ABCB1 mRNA	26394120
D000077185	Resveratrol	Resveratrol inhibits the reaction [ABCB1 protein results in increased transport of Methotrexate]	27377006
C003300	retrorsine	ABCB1 protein results in increased export of retrorsine	24799337
C003300	retrorsine	Cyclosporine inhibits the reaction [ABCB1 protein results in increased export of retrorsine]	24799337
C120261	reversin 205	reversin 205 results in decreased activity of ABCB1 protein	26929997
C120261	reversin 205	[reversin 205 results in decreased activity of ABCB1 protein] which results in decreased export of calcein AM	26929997
D020112	Rhodamine 123	ABCB1 protein results in increased export of Rhodamine 123	28093773
D020112	Rhodamine 123	5-oxo-hexahydroquinoline analog inhibits the reaction [ABCB1 protein results in increased export of Rhodamine 123]	30391378
D020112	Rhodamine 123	ABCB1 protein results in increased export of Rhodamine 123	25058526; 27816545; 30391378;
D020112	Rhodamine 123	abemaciclib inhibits the reaction [ABCB1 protein results in increased export of Rhodamine 123]	27816545
D020112	Rhodamine 123	CEP 33779 inhibits the reaction [ABCB1 protein results in increased export of Rhodamine 123]	25058526
D020112	Rhodamine 123	Verapamil inhibits the reaction [ABCB1 protein results in increased export of Rhodamine 123]	30391378
C009172	rhodioloside	rhodioloside affects the reaction [ABCB1 protein results in increased transport of Digoxin]	24380838
C013672	riddelliine	riddelliine results in increased expression of ABCB1 mRNA	18047722
D012293	Rifampin	[Rifampin co-treated with Colforsin] results in increased expression of ABCB1 protein	23164983
D012293	Rifampin	Rifampin results in increased expression of ABCB1 mRNA	23164983
D012293	Rifampin	Rifampin results in increased expression of ABCB1 protein	23164983
D012293	Rifampin	Rifampin results in increased expression of ABCB1 mRNA	22620706
D012293	Rifampin	Rifampin results in increased expression of ABCB1 protein	22620706
D012293	Rifampin	Rifampin results in increased expression of ABCB1 mRNA	22559005
D012293	Rifampin	Camptothecin inhibits the reaction [Rifampin results in increased expression of ABCB1 mRNA]	29356861
D012293	Rifampin	Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 mRNA]]	23707768
D012293	Rifampin	Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 protein]]	23707768
D012293	Rifampin	Ketoconazole inhibits the reaction [Rifampin results in increased expression of ABCB1 mRNA]	16819505; 25542144;
D012293	Rifampin	Ketoconazole inhibits the reaction [Rifampin results in increased expression of ABCB1 protein]	16819505; 20624464;
D012293	Rifampin	mulberroside A inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 mRNA]	27918128
D012293	Rifampin	mulberroside A inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 protein]	27918128
D012293	Rifampin	NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 mRNA]	23707768
D012293	Rifampin	NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 protein]	23707768
D012293	Rifampin	[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 mRNA	27918128
D012293	Rifampin	[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 protein	27918128
D012293	Rifampin	pimecrolimus inhibits the reaction [Rifampin results in increased expression of ABCB1 mRNA]	29356861
D012293	Rifampin	Resveratrol inhibits the reaction [Rifampin results in increased expression of ABCB1 protein]	26394120
D012293	Rifampin	Rifampin affects the activity of ABCB1 protein	15964336
D012293	Rifampin	[Rifampin binds to and results in increased activity of NR1I2 protein] promotes the reaction [ABCB1 protein results in decreased uptake of Doxorubicin]	20041327
D012293	Rifampin	Rifampin promotes the reaction [ABCB1 protein results in increased transport of Digoxin]	17365992
D012293	Rifampin	[Rifampin results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 protein	20624464
D012293	Rifampin	Rifampin results in increased expression of ABCB1 mRNA	11744607; 14722322; 15276086; 15290871; 15710169; 16819505; 16837569; 16842400; 17003290; 17191263; 17365992; 18094037; 19647009; 20018165; 22258563; 22914566; 23707768; 24259679; 24552687; 25313206; 26394120; 27199754; 27871908; 29356861; 30071242; 31233785;
D012293	Rifampin	Rifampin results in increased expression of ABCB1 protein	16819505; 16842400; 17365992; 19148864; 20624464; 23707768; 26301745; 26394120; 27918128; 8632764;
D012293	Rifampin	Rifampin results in increased expression of ABCB1 mRNA	25542188
D012293	Rifampin	Rifampin results in increased expression of ABCB1 protein	25542188
D000078262	Rifaximin	Rifaximin results in increased expression of ABCB1 mRNA	21141967
D018967	Risperidone	ABCB1 gene polymorphism affects the abundance of Risperidone	17541883; 18708991; 20563569; 21449914; 22623266;
D018967	Risperidone	ABCB1 gene polymorphism affects the susceptibility to Risperidone	17054409
D018967	Risperidone	ABCB1 protein affects the abundance of Risperidone	17541883; 18708991; 20563569; 21449914; 22623266;
D018967	Risperidone	ABCB1 protein affects the susceptibility to Risperidone	17054409
D018967	Risperidone	ABCB1 protein results in increased susceptibility to Risperidone	19997080
D018967	Risperidone	ABCB1 protein results in increased transport of Risperidone	22691713
D018967	Risperidone	Risperidone inhibits the reaction [ABCB1 protein results in decreased export of Doxorubicin]	16936711
D018967	Risperidone	Risperidone results in decreased activity of ABCB1 protein	16810505; 16936711;
D019438	Ritonavir	allicin inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir]	15266218
D019438	Ritonavir	hypericin inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir]	15266218
D019438	Ritonavir	kaempferol inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir]	15266218
D019438	Ritonavir	Quercetin inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir]	15266218
D019438	Ritonavir	hyperforin inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir]	15266218
C057006	Ro 21-5104	Ro 21-5104 results in increased expression of ABCB1 mRNA	25313206
C087123	romidepsin	ABCB1 protein binds to and affects the export of romidepsin	15634944
C087123	romidepsin	ABCB1 protein results in decreased susceptibility to romidepsin	16049968
C087123	romidepsin	romidepsin promotes the reaction [Tretinoin results in increased expression of ABCB1 mRNA]	16223781
C087123	romidepsin	romidepsin results in increased acetylation of ABCB1 promoter	16223781
C087123	romidepsin	romidepsin results in increased expression of ABCB1 mRNA	15833893; 16223781;
C087123	romidepsin	romidepsin results in increased expression of ABCB1 protein	15634944; 15833893;
C087123	romidepsin	[[Tretinoin co-treated with romidepsin] results in increased expression of ABCB1 mRNA] which results in decreased susceptibility to Doxorubicin	16223781
C087123	romidepsin	[Tretinoin co-treated with romidepsin] results in increased expression of ABCB1 protein	16223781
C087123	romidepsin	Tretinoin promotes the reaction [romidepsin results in increased acetylation of ABCB1 promoter]	16223781
C087123	romidepsin	valspodar inhibits the reaction [[[Tretinoin co-treated with romidepsin] results in increased expression of ABCB1 mRNA] which results in decreased susceptibility to Doxorubicin]	16223781
D012395	Rose Bengal	Rose Bengal results in decreased activity of ABCB1 protein	20041016
C053775	rosemary oil	rosemary oil results in increased expression of ABCB1 mRNA	30071242
D000077154	Rosiglitazone	Rosiglitazone results in increased expression of ABCB1 mRNA	31233785
C106263	rostafuroxin	[LSS gene polymorphism co-treated with HSD3B1 gene polymorphism co-treated with ABCB1 gene polymorphism co-treated with ADD1 gene polymorphism co-treated with ADD3 gene polymorphism] affects the susceptibility to rostafuroxin	21106941
D012402	Rotenone	Rotenone affects the activity of ABCB1 protein	15796199
C046245	rubimaillin	dorsomorphin inhibits the reaction [rubimaillin results in decreased expression of ABCB1 mRNA]	23466342
C046245	rubimaillin	rubimaillin inhibits the reaction [RELA protein results in increased expression of ABCB1 protein]	23466342
C046245	rubimaillin	rubimaillin results in decreased expression of ABCB1 mRNA	23466342
C046245	rubimaillin	rubimaillin results in decreased expression of ABCB1 protein	23466342
D019258	Saquinavir	ABCB1 protein affects the export of Saquinavir	15832500
D019258	Saquinavir	ABCB1 protein results in increased export of Saquinavir	18535159
D012524	Sarin	Sarin results in decreased expression of ABCB1 mRNA	19522546
D012530	Saxitoxin	Saxitoxin affects the activity of ABCB1 protein	29128272
D012530	Saxitoxin	[Thioctic Acid co-treated with Saxitoxin] affects the activity of ABCB1 protein	29128272
D012601	Scopolamine	Scopolamine results in decreased expression of ABCB1 mRNA	12818353
C548487	secomilbemycin D	secomilbemycin D results in decreased expression of ABCB1 protein	21458446
D020280	Sertraline	Sertraline results in increased activity of ABCB1 protein	23273999
D012717	Sesquiterpenes	Sesquiterpenes analog binds to and affects the activity of ABCB1 protein	15466210
D012717	Sesquiterpenes	Sesquiterpenes analog inhibits the reaction [ABCB1 protein affects the transport of Colchicine]	15466210
D012717	Sesquiterpenes	Sesquiterpenes analog inhibits the reaction [ABCB1 protein affects the transport of tetramethylrosamine]	15466210
D012717	Sesquiterpenes	Sesquiterpenes analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Daunorubicin]	15466210
D012717	Sesquiterpenes	Sesquiterpenes analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vinblastine]	15466210
D019821	Simvastatin	ABCB1 alternative form affects the reaction [CYP3A4 polymorphism affects the susceptibility to Simvastatin]	19802823
D019821	Simvastatin	ABCB1 polymorphism affects the susceptibility to Simvastatin	16321621; 19891551;
D019821	Simvastatin	ABCB1 protein results in increased transport of Simvastatin	15616150
D019821	Simvastatin	Simvastatin analog inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	15616150
D019821	Simvastatin	Simvastatin analog results in decreased activity of ABCB1 protein	15616150
D019821	Simvastatin	ABCB1 results in increased transport of Simvastatin	19802823
D020123	Sirolimus	ABCB1 protein affects the metabolism of Sirolimus	15707415; 15760093;
D020123	Sirolimus	ABCB1 protein affects the transport of Sirolimus	15964407
C504100	S-methyl N,N-diethylthiocarbamate sulfone	S-methyl N,N-diethylthiocarbamate sulfone results in decreased activity of ABCB1 protein	16028354
C073220	S-methyl N,N-diethylthiolcarbamate sulfoxide	S-methyl N,N-diethylthiolcarbamate sulfoxide results in decreased activity of ABCB1 protein	16028354
D012906	Smoke	Smoke results in decreased activity of ABCB1 protein	19135510
C534922	SNX 2112	SNX 2112 results in decreased expression of and results in decreased activity of ABCB1 protein	23777986
C017947	sodium arsenite	Dactinomycin inhibits the reaction [sodium arsenite results in increased expression of ABCB1 mRNA]	1967174
C017947	sodium arsenite	Dichlororibofuranosylbenzimidazole inhibits the reaction [sodium arsenite results in increased expression of ABCB1 protein]	16121039
C017947	sodium arsenite	sodium arsenite promotes the reaction [ABCB1 protein results in increased secretion of calcein AM]	16121039
C017947	sodium arsenite	sodium arsenite results in increased expression of ABCB1 mRNA	1967174
C017947	sodium arsenite	sodium arsenite results in increased expression of ABCB1 protein	16121039; 1967174;
C017947	sodium arsenite	[sodium arsenite results in increased expression of ABCB1 protein] which results in decreased susceptibility to Vinblastine	1967174
C017947	sodium arsenite	[Verapamil binds to and results in decreased activity of ABCB1 protein] inhibits the reaction [sodium arsenite promotes the reaction [ABCB1 protein results in increased secretion of calcein AM]]	16121039
C017947	sodium arsenite	ABCB1 protein results in increased secretion of sodium arsenite	28472378
C017947	sodium arsenite	sodium arsenite results in decreased expression of ABCB1 mRNA	31532247
C017947	sodium arsenite	sodium arsenite results in increased expression of ABCB1 mRNA	15694464
C017947	sodium arsenite	ABCB1 protein results in decreased susceptibility to sodium arsenite	11455017
C017947	sodium arsenite	sodium arsenite results in increased expression of ABCB1 mRNA	11408547; 11455017;
C017947	sodium arsenite	sodium arsenite results in increased expression of ABCB1 protein	11455017
D019810	Sodium Azide	[Sodium Azide co-treated with Iodoacetates] inhibits the reaction [ABCB1 protein results in increased export of Daunorubicin]	12526924
D019810	Sodium Azide	Sodium Azide inhibits the reaction [ABCB1 protein results in increased export of Diazinon]	16221533
D013015	Sotalol	ABCB1 protein results in increased transport of Sotalol	16671962
D013015	Sotalol	valspodar inhibits the reaction [ABCB1 protein results in increased transport of Sotalol]	16671962
D013134	Spiperone	Spiperone inhibits the reaction [Bromocriptine results in increased expression of ABCB1 protein]	9111066
D013134	Spiperone	Spiperone inhibits the reaction [N-n-propylnorapomorphine results in increased expression of ABCB1 protein]	9111066
D013134	Spiperone	Spiperone inhibits the reaction [Quinpirole results in increased expression of ABCB1 protein]	9111066
D013148	Spironolactone	Ketoconazole inhibits the reaction [Spironolactone results in increased expression of ABCB1 protein]	21459122
D013148	Spironolactone	NR1I2 affects the reaction [Spironolactone results in increased expression of ABCB1 protein]	21459122
D013148	Spironolactone	Spironolactone results in increased expression of ABCB1 mRNA	21459122
D013148	Spironolactone	Spironolactone results in increased expression of ABCB1 protein	21459122
C100355	SR 12813	[SR 12813 results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA	19746521
C100355	SR 12813	SR 12813 results in increased expression of ABCB1 mRNA	19746521
D018119	Stavudine	Stavudine results in increased expression of ABCB1 mRNA	18310046
D013327	Strophanthidin	ABCB1 protein results in increased transport of Strophanthidin	26708294
D004113	Succimer	[Succimer co-treated with Magnetite Nanoparticles] results in increased expression of ABCB1 mRNA	26378955
C033308	sulconazole	sulconazole results in increased expression of ABCB1 mRNA	31312845
C063871	sulfinosine	[sulfinosine co-treated with Curcumin] results in decreased expression of ABCB1 mRNA	18414057
C063871	sulfinosine	sulfinosine results in decreased expression of ABCB1 mRNA	18414057
C016766	sulforafan	sulforafan inhibits the reaction [ginkgolide B results in increased expression of ABCB1 mRNA]	26775663
C016766	sulforafan	sulforafan results in decreased expression of ABCB1 mRNA	26775663
D013469	Sulpiride	ABCB1 protein results in increased transport of Sulpiride	28597291
D013469	Sulpiride	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Sulpiride]	28597291
D000077210	Sunitinib	Sunitinib results in increased expression of ABCB1 mRNA	26797788
D000077210	Sunitinib	Sunitinib results in increased expression of ABCB1 protein	26797788
C446685	systhane	systhane results in increased expression of ABCB1 mRNA	19409404
D016559	Tacrolimus	ABCB1 gene SNP results in increased susceptibility to Tacrolimus	12352921
D016559	Tacrolimus	ABCB1 protein affects the export of Tacrolimus	15919446; 15964336;
D016559	Tacrolimus	ABCB1 protein affects the susceptibility to Tacrolimus	15919446
D016559	Tacrolimus	ABCB1 protein results in increased export of Tacrolimus	11920757
D016559	Tacrolimus	[Tacrolimus binds to ABCB1 protein] inhibits the reaction [azidoprazosin binds to ABCB1 protein]	1381629
D016559	Tacrolimus	Tacrolimus results in decreased activity of ABCB1 protein	20080907
D016559	Tacrolimus	[Tacrolimus results in decreased activity of ABCB1 protein] which results in decreased export of Dexamethasone	20080907
D016559	Tacrolimus	Verapamil affects the reaction [ABCB1 protein results in increased export of Tacrolimus]	11920757
C508967	tamarixetin	tamarixetin results in increased expression of ABCB1 mRNA	26238175
D013629	Tamoxifen	[Celecoxib results in decreased expression of ABCB1] which results in increased susceptibility to Tamoxifen	19562670
D013629	Tamoxifen	NR1I2 protein promotes the reaction [Tamoxifen results in increased expression of ABCB1 protein]	20041327
D013629	Tamoxifen	Tamoxifen inhibits the reaction [Estradiol results in decreased expression of ABCB1 protein]	16925584
D013629	Tamoxifen	[Tamoxifen results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA	20041327
D013629	Tamoxifen	Tamoxifen results in increased expression of ABCB1 protein	15290871; 20041327;
D013629	Tamoxifen	Tamoxifen affects the reaction [ABCB1 protein results in increased secretion of Doxorubicin]	15937726
D013629	Tamoxifen	Tamoxifen inhibits the reaction [Doxorubicin affects the activity of ABCB1 protein]	15937726
D013629	Tamoxifen	Tamoxifen binds to ABCB1 protein	7808368
C402343	tariquidar	tariquidar inhibits the reaction [ABCB1 protein results in increased susceptibility to NSC73306]	21721528
C402343	tariquidar	tariquidar inhibits the reaction [ABCB1 protein results in increased transport of Fentanyl]	29669042
C402343	tariquidar	tariquidar results in decreased activity of ABCB1 protein	15494300; 29669042;
C402343	tariquidar	tariquidar results in decreased activity of ABCB1 protein	21600273; 27287416;
C402343	tariquidar	[tariquidar results in decreased activity of ABCB1 protein] which results in increased abundance of asoxime chloride	21600273
D013656	Taurocholic Acid	Taurocholic Acid results in increased expression of ABCB1 protein	11113123
C080625	taxane	taxane analog affects the activity of ABCB1 protein	15771464
D043823	Taxoids	ABCB1 protein results in decreased susceptibility to Taxoids analog	29625142
D043823	Taxoids	Taxoids analog results in increased expression of and binds to and results in increased activity of ABCB1 protein	29625142
C082026	tebufenozide	ABCB1 protein results in increased transport of tebufenozide	26995013
C082026	tebufenozide	tebufenozide inhibits the reaction [ABCB1 protein results in increased transport of Quinidine]	26995013
D017256	Technetium Tc 99m Sestamibi	ABCB1 gene mutant form results in decreased transport of Technetium Tc 99m Sestamibi	19754906
D017256	Technetium Tc 99m Sestamibi	[Ketoconazole results in decreased activity of ABCB1 protein] which results in decreased transport of Technetium Tc 99m Sestamibi	19754906
D017256	Technetium Tc 99m Sestamibi	ABCB1 gene polymorphism affects the export of Technetium Tc 99m Sestamibi	16896007
C076852	terameprocol	terameprocol inhibits the reaction [Doxorubicin results in increased expression of ABCB1 mRNA]	16544145
C076852	terameprocol	terameprocol inhibits the reaction [SP1 protein results in increased expression of ABCB1 mRNA]	16544145
C076852	terameprocol	terameprocol results in decreased expression of ABCB1 mRNA	16544145
D016593	Terfenadine	ABCB1 protein affects the transport of Terfenadine	10350002
D016593	Terfenadine	ABCB1 protein affects the transport of Terfenadine analog	10350002
D016593	Terfenadine	Terfenadine results in decreased activity of ABCB1 protein	7905786
C021754	terics	terics results in decreased activity of ABCB1 protein	11408081
C027009	terpinolene	terpinolene inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
C045037	testosterone-3-carboxymethyloxime-bovine serum albumin conjugate	testosterone-3-carboxymethyloxime-bovine serum albumin conjugate affects the expression of ABCB1 mRNA	20189893
C020806	tetrabromobisphenol A	tetrabromobisphenol A results in decreased activity of ABCB1 protein	24014645
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of ABCB1 mRNA	16837569; 20106945; 21632981; 26238291;
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of ABCB1 protein	22472606
D013752	Tetracycline	Tetracycline results in increased expression of ABCB1 mRNA	17522070; 19224547;
D013755	Tetradecanoylphorbol Acetate	5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]	20438634; 20438634;
D013755	Tetradecanoylphorbol Acetate	[ABCB1 protein results in decreased susceptibility to Doxorubicin] affects the reaction [5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]]	20438634
D013755	Tetradecanoylphorbol Acetate	[ABCB1 protein results in decreased susceptibility to Doxorubicin] affects the reaction [eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]]	20438634
D013755	Tetradecanoylphorbol Acetate	[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]	20438634; 20438634;
D013755	Tetradecanoylphorbol Acetate	eriodictyol inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]	20438634; 20438634;
D013755	Tetradecanoylphorbol Acetate	kaempferol inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]	20438634; 20438634;
D013755	Tetradecanoylphorbol Acetate	Quercetin inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]	20438634; 20438634;
D013755	Tetradecanoylphorbol Acetate	withaferin A inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]	20438634; 20438634;
D013755	Tetradecanoylphorbol Acetate	[Tetradecanoylphorbol Acetate co-treated with Ionomycin] affects the expression of ABCB1 mRNA	25613284
C412715	tetramethylrosamine	Sesquiterpenes analog inhibits the reaction [ABCB1 protein affects the transport of tetramethylrosamine]	15466210
C412715	tetramethylrosamine	tetramethylrosamine inhibits the reaction [ABCB1 protein results in increased transport of cypermethrin]	17490606
C412715	tetramethylrosamine	tetramethylrosamine inhibits the reaction [ABCB1 protein results in increased transport of Endosulfan]	17490606
C412715	tetramethylrosamine	tetramethylrosamine inhibits the reaction [ABCB1 protein results in increased transport of fenvalerate]	17490606
C412715	tetramethylrosamine	tetramethylrosamine inhibits the reaction [ABCB1 protein results in increased transport of Methyl Parathion]	17490606
C009438	tetrandrine	tetrandrine results in decreased expression of ABCB1	19840446
D013792	Thalidomide	Thalidomide results in decreased activity of ABCB1 protein	19840843
D013792	Thalidomide	Thalidomide results in decreased expression of ABCB1 mRNA	15920492
D013792	Thalidomide	Thalidomide results in decreased expression of ABCB1 protein	19840843
C022616	thiazolyl blue	thiazolyl blue results in decreased activity of ABCB1 protein	15451006
D013853	Thioacetamide	[Thioacetamide co-treated with Cyclosporine] results in increased expression of ABCB1 mRNA	15770714
D013853	Thioacetamide	Thioacetamide results in increased expression of ABCB1 mRNA	26222700
D013853	Thioacetamide	Thioacetamide results in increased expression of ABCB1 protein	26222700
D008063	Thioctic Acid	[Thioctic Acid co-treated with Saxitoxin] affects the activity of ABCB1 protein	29128272
C027971	thiodicarb	ABCB1 protein results in decreased susceptibility to thiodicarb	8898877
C027971	thiodicarb	ABCB1 protein results in increased export of and results in decreased susceptibility to thiodicarb	8644124
C027971	thiodicarb	Quinidine inhibits the reaction [ABCB1 protein results in decreased susceptibility to thiodicarb]	8898877
C027971	thiodicarb	Quinidine inhibits the reaction [ABCB1 protein results in increased export of and results in decreased susceptibility to thiodicarb]	8644124
D000078308	Tiagabine	Amino Acids, Peptides, and Proteins inhibits the reaction [Tiagabine results in increased expression of ABCB1 protein]	18473823
D000078308	Tiagabine	Tiagabine results in increased expression of ABCB1 protein	18473823
C016151	tinuvin	tinuvin analog results in decreased expression of ABCB1 mRNA	30315675
D008625	Tiopronin	Tiopronin results in decreased expression of ABCB1 protein	21657271
D008625	Tiopronin	[Tiopronin results in decreased expression of ABCB1 protein] which results in increased susceptibility to Doxorubicin	21657271
D008625	Tiopronin	[Tiopronin results in decreased expression of ABCB1 protein] which results in increased susceptibility to Paclitaxel	21657271
D008625	Tiopronin	Tiopronin results in decreased stability of and results in decreased expression of ABCB1 mRNA	21657271
C402769	tipifarnib	ABCB1 gene SNP affects the susceptibility to tipifarnib	15122075
C009495	titanium dioxide	titanium dioxide inhibits the reaction [Cadmium Chloride results in increased expression of ABCB1 mRNA]	25956639
C009495	titanium dioxide	titanium dioxide results in increased transport of ABCB1 protein	25956639
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution inhibits the reaction [ABCB1 protein results in increased export of Fluorescent Dyes]	27450509
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in increased expression of ABCB1 mRNA	28111298
C014225	tocophersolan	[methoxy poly(ethylene glycol-co-epsilon-caprolactone) co-treated with tocophersolan co-treated with Resveratrol] results in decreased expression of ABCB1 protein	25392124
C082032	tocotrienol, alpha	tocotrienol, alpha results in increased expression of ABCB1	15269186
C082089	tocotrienol, beta	tocotrienol, beta results in increased expression of ABCB1	15269186
C082097	tocotrienol, delta	tocotrienol, delta results in increased expression of ABCB1	15269186
D014050	Toluene	Toluene affects the expression of ABCB1 mRNA	18653662
D000077236	Topiramate	Amino Acids, Peptides, and Proteins inhibits the reaction [Topiramate results in increased expression of ABCB1 protein]	18473823
D000077236	Topiramate	Topiramate results in increased expression of ABCB1 protein	18473823
D019772	Topotecan	[chrysin results in decreased activity of ABCB1 protein] which results in decreased export of Topotecan	20457140
D019772	Topotecan	Topotecan results in increased expression of ABCB1 protein	20457140
D019772	Topotecan	[Verapamil results in decreased activity of ABCB1 protein] which results in decreased export of Topotecan	20457140
D014212	Tretinoin	romidepsin promotes the reaction [Tretinoin results in increased expression of ABCB1 mRNA]	16223781
D014212	Tretinoin	[Tretinoin co-treated with Phenylbutyrates co-treated with 1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene] results in increased expression of ABCB1 protein	23284745
D014212	Tretinoin	[[Tretinoin co-treated with romidepsin] results in increased expression of ABCB1 mRNA] which results in decreased susceptibility to Doxorubicin	16223781
D014212	Tretinoin	[Tretinoin co-treated with romidepsin] results in increased expression of ABCB1 protein	16223781
D014212	Tretinoin	Tretinoin promotes the reaction [romidepsin results in increased acetylation of ABCB1 promoter]	16223781
D014212	Tretinoin	Tretinoin results in increased acetylation of ABCB1 promoter	16223781
D014212	Tretinoin	Tretinoin results in increased expression of ABCB1 mRNA	16223781
D014212	Tretinoin	valspodar inhibits the reaction [[[Tretinoin co-treated with romidepsin] results in increased expression of ABCB1 mRNA] which results in decreased susceptibility to Doxorubicin]	16223781
C032910	triadimefon	triadimefon results in increased expression of ABCB1 mRNA	19409404
C032910	triadimefon	triadimefon results in decreased expression of ABCB1 mRNA	19409404
C011559	tributyltin	tributyltin results in increased activity of ABCB1 protein	23690080
C011559	tributyltin	tributyltin results in decreased expression of ABCB1 protein	26079211
D014241	Trichloroethylene	Trichloroethylene results in increased expression of ABCB1 mRNA	17905399
C012589	trichostatin A	[[Decitabine co-treated with trichostatin A] affects the methylation of ABCB1 gene] which affects the expression of ABCB1 mRNA	18673531; 18673531;
C012589	trichostatin A	Decitabine promotes the reaction [trichostatin A results in increased expression of ABCB1 mRNA]	27570640
C012589	trichostatin A	[trichostatin A affects the methylation of ABCB1 gene] which affects the expression of ABCB1 mRNA	18673531; 18673531;
C012589	trichostatin A	trichostatin A results in increased expression of ABCB1 mRNA	24935251; 27570640;
D014260	Triclosan	Triclosan results in increased expression of ABCB1 mRNA	29849464
D014268	Trifluoperazine	Trifluoperazine inhibits the reaction [avermectin results in increased expression of ABCB1 protein]	23523950
D014268	Trifluoperazine	Trifluoperazine results in increased activity of ABCB1 protein	2900677
C114675	trimethoxybenzoylyohimbine	trimethoxybenzoylyohimbine results in increased expression of ABCB1 mRNA	7476894
D014302	Trinitrobenzenesulfonic Acid	Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of ABCB1 mRNA]	18200517
D014302	Trinitrobenzenesulfonic Acid	Trinitrobenzenesulfonic Acid results in decreased expression of ABCB1 mRNA	18200517
C510683	tripeptide tyroservatide	tripeptide tyroservatide results in decreased expression of ABCB1 mRNA	18538471
C510683	tripeptide tyroservatide	tripeptide tyroservatide results in decreased expression of ABCB1 protein	18538471
C016805	tris(1,3-dichloro-2-propyl)phosphate	tris(1,3-dichloro-2-propyl)phosphate results in increased expression of ABCB1 mRNA	26179874
D014217	Troleandomycin	Troleandomycin inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]	12235267
D014217	Troleandomycin	Troleandomycin inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]	12235267
C003330	trospium chloride	ABCB1 protein results in increased transport of trospium chloride	25466967
C003330	trospium chloride	valspodar inhibits the reaction [ABCB1 protein results in increased transport of trospium chloride]	25466967
C003330	trospium chloride	ABCB1 protein results in increased metabolism of trospium chloride	25466967
C046243	tryptanthrine	tryptanthrine binds to ABCB1 promoter	17482571
C046243	tryptanthrine	tryptanthrine results in decreased expression of ABCB1 mRNA	17482571
C046243	tryptanthrine	tryptanthrine results in decreased expression of ABCB1 protein	17482571
C010522	tryptoquivaline	tryptoquivaline inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	18829547
D014415	Tunicamycin	Tunicamycin results in increased expression of ABCB1 mRNA	29453283
C012596	turmeric extract	ABCB1 affects the susceptibility to turmeric extract	15476675
C113580	U 0126	U 0126 results in decreased expression of ABCB1 mRNA	15526378
C113580	U 0126	U 0126 results in decreased expression of ABCB1 protein	15526378
C113580	U 0126	U 0126 results in increased expression of ABCB1 mRNA	24819614
D014520	Urethane	Urethane results in increased expression of ABCB1 mRNA	28818685
D014580	Ursodeoxycholic Acid	Ursodeoxycholic Acid results in increased expression of ABCB1 mRNA	16678547
C406224	valdecoxib	valdecoxib results in increased expression of ABCB1 mRNA	24136188
D014635	Valproic Acid	ABCB1 protein affects the susceptibility to Valproic Acid	14749549
D014635	Valproic Acid	Valproic Acid affects the expression of ABCB1 mRNA	25979313
D014635	Valproic Acid	Valproic Acid results in decreased activity of ABCB1 protein	18408562
D014635	Valproic Acid	Valproic Acid results in decreased methylation of ABCB1 gene	29154799; 29501571;
D014635	Valproic Acid	Valproic Acid results in increased expression of ABCB1 mRNA	19949822; 23179753; 24935251; 25192806; 28001369; 29154799;
D014635	Valproic Acid	Valproic Acid results in increased expression of ABCB1 protein	15569486
C070272	valspodar	valspodar results in decreased activity of ABCB1 protein	10898547
C070272	valspodar	[valspodar results in decreased activity of ABCB1 protein] promotes the reaction [Doxorubicin results in decreased secretion of Hydrocortisone]	10898547
C070272	valspodar	[valspodar results in decreased activity of ABCB1 protein] promotes the reaction [Mitotane results in decreased secretion of Hydrocortisone]	10898547
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]	24975508
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein affects the susceptibility to Vincristine]	24975508
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	15492788
C070272	valspodar	deoxynivalenol inhibits the reaction [valspodar inhibits the reaction [ABCB1 protein results in increased export of calcein AM]]	29174985
C070272	valspodar	valspodar affects the activity of ABCB1 protein	15788683
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	17947497
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in decreased susceptibility to N-caproylsphingosine]	21436125
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in decreased uptake of Doxorubicin]	17947497
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased export of calcein AM]	29174985
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased export of Daunorubicin]	9815696
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased export of Diazinon]	16221533
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased export of Paraquat]	25015657
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased secretion of Aldosterone]	22464980
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased secretion of Beclomethasone]	22464980
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased secretion of Dexamethasone]	22464980
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased secretion of Fluticasone]	22464980
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased secretion of Hydrocortisone]	22464980
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased secretion of Methylprednisolone]	22464980
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased secretion of Prednisone]	22464980
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased susceptibility to NSC73306]	21721528
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased transport of Bisoprolol]	16671962
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased transport of Carvedilol]	16671962
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	16671962
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased transport of Sotalol]	16671962
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in increased transport of trospium chloride]	25466967
C070272	valspodar	valspodar inhibits the reaction [[[Tretinoin co-treated with romidepsin] results in increased expression of ABCB1 mRNA] which results in decreased susceptibility to Doxorubicin]	16223781
C070272	valspodar	valspodar results in decreased activity of ABCB1 protein	10997946; 11934808; 16810505; 25015657;
C070272	valspodar	[valspodar results in decreased activity of ABCB1 protein] which results in decreased transport of Digoxin	10997946
C070272	valspodar	[valspodar results in decreased activity of ABCB1 protein] which results in decreased transport of Xanthenes	21436125
C070272	valspodar	[valspodar results in decreased activity of ABCB1 protein] which results in increased susceptibility to Paclitaxel	18673531
C070272	valspodar	valspodar inhibits the reaction [ABCB1 protein results in decreased susceptibility to Cadmium]	21436125
C070272	valspodar	valspodar inhibits the reaction [ABCB1 results in decreased susceptibility to Cadmium Chloride]	10636889
C070272	valspodar	valspodar results in decreased activity of ABCB1 protein	11455017; 12387749; 12531223; 15456083; 16356829; 17097285; 21436125; 24448832;
D014638	Vanadates	Vanadates results in decreased activity of ABCB1 protein	2900677; 29625142;
D014640	Vancomycin	Cilastatin inhibits the reaction [Vancomycin results in decreased expression of and affects the localization of ABCB1 protein]	28549670
D014640	Vancomycin	Vancomycin results in decreased expression of and affects the localization of ABCB1 protein	28549670
D001335	Vehicle Emissions	acetovanillone inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D001335	Vehicle Emissions	Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D001335	Vehicle Emissions	CAT protein inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D001335	Vehicle Emissions	Cycloheximide inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D001335	Vehicle Emissions	Cycloheximide inhibits the reaction [[Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]	18474546
D001335	Vehicle Emissions	Dactinomycin inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D001335	Vehicle Emissions	Dactinomycin inhibits the reaction [[Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]	18474546
D001335	Vehicle Emissions	diphenyleneiodonium inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D001335	Vehicle Emissions	pyrazolanthrone inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D001335	Vehicle Emissions	TIMP3 protein inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D001335	Vehicle Emissions	TNF protein affects the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D001335	Vehicle Emissions	TNFRSF1A protein affects the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]	18474546
D001335	Vehicle Emissions	Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein	18474546
D001335	Vehicle Emissions	[Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine	18474546
C521013	veliparib	ABCB1 protein results in increased transport of veliparib	21436403
D000069470	Venlafaxine Hydrochloride	Venlafaxine Hydrochloride results in increased expression of ABCB1 mRNA	17191263
D000069470	Venlafaxine Hydrochloride	ABCB1 protein results in increased export of Venlafaxine Hydrochloride	14550684
D014700	Verapamil	Verapamil results in decreased activity of ABCB1 protein	15666293
D014700	Verapamil	[Verapamil results in decreased activity of ABCB1 protein] which affects the transport of Digoxin	20510202
D014700	Verapamil	Verapamil results in decreased activity of ABCB1 protein	26929997
D014700	Verapamil	[Verapamil results in decreased activity of ABCB1 protein] which results in decreased export of calcein AM	26929997
D014700	Verapamil	Verapamil inhibits the reaction [[avermectin results in increased abundance of Calcium] which results in increased expression of ABCB1 protein]	23523950
D014700	Verapamil	Verapamil results in decreased expression of ABCB1 protein	23523950
D014700	Verapamil	Verapamil results in decreased activity of ABCB1 protein	24498193
D014700	Verapamil	[Verapamil results in decreased activity of ABCB1 protein] which results in increased uptake of Enrofloxacin	24498193
D014700	Verapamil	ABCB1 protein results in increased transport of Verapamil	23976943; 26995013;
D014700	Verapamil	Colchicine inhibits the reaction [Verapamil analog results in increased activity of ABCB1 protein mutant form]	12711602
D014700	Verapamil	Cyclosporine inhibits the reaction [Verapamil analog results in increased activity of ABCB1 protein mutant form]	12711602
D014700	Verapamil	Demecolcine inhibits the reaction [Verapamil analog results in increased activity of ABCB1 protein mutant form]	12711602
D014700	Verapamil	Diazinon promotes the reaction [Verapamil inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
D014700	Verapamil	Diazinon promotes the reaction [Verapamil results in decreased activity of ABCB1 protein]	21783720
D014700	Verapamil	[Endosulfan co-treated with Verapamil] inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
D014700	Verapamil	[Endosulfan co-treated with Verapamil] results in decreased activity of ABCB1 protein	21783720
D014700	Verapamil	[phosalone co-treated with Verapamil] inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
D014700	Verapamil	[phosalone co-treated with Verapamil] results in decreased activity of ABCB1 protein	21783720
D014700	Verapamil	propiconazole promotes the reaction [Verapamil inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
D014700	Verapamil	propiconazole promotes the reaction [Verapamil results in decreased activity of ABCB1 protein]	21783720
D014700	Verapamil	Verapamil affects the reaction [ABCB1 protein results in increased export of Tacrolimus]	11920757
D014700	Verapamil	Verapamil analog results in increased activity of ABCB1 protein mutant form	12711602
D014700	Verapamil	Verapamil binds to and results in decreased activity of ABCB1 protein	10527640; 16959878; 23976943; 24321342;
D014700	Verapamil	[Verapamil binds to and results in decreased activity of ABCB1 protein] inhibits the reaction [sodium arsenite promotes the reaction [ABCB1 protein results in increased secretion of calcein AM]]	16121039
D014700	Verapamil	[Verapamil binds to and results in decreased activity of ABCB1 protein] which results in decreased export of Digoxin	23976943
D014700	Verapamil	[Verapamil binds to and results in decreased activity of ABCB1 protein] which results in decreased transport of N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide	24321342
D014700	Verapamil	Verapamil inhibits the reaction [5-Methoxypsoralen results in decreased activity of ABCB1 protein]	29079042
D014700	Verapamil	Verapamil inhibits the reaction [[5-Methoxypsoralen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of Daunorubicin]	29079042
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein affects the uptake of Vinblastine]	15640379
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in decreased abundance of Quercetin]	15112361
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]	17947497; 22233293; 24321342; 25058526; 7083125;
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]	22233293; 25058526;
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]	25058526
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in decreased uptake of Doxorubicin]	17526808; 17947497;
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in increased export of calcein AM]	29174985
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]	8917702
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in increased export of fluorexon]	16442095
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in increased export of Rhodamine 123]	30391378
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]	21783720
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]	12708479
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]	10527640; 11895100; 24380838;
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Doxorubicin]	12708479
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of huperzine A]	28587984
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide]	24321342
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Paclitaxel]	12708479
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	25268938; 31348918;
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Sulpiride]	28597291
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Vinblastine]	12708479
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]	16904803
D014700	Verapamil	Verapamil inhibits the reaction [Acetaminophen results in increased activity of ABCB1 protein]	16930294; 17526808;
D014700	Verapamil	Verapamil inhibits the reaction [Doxorubicin results in increased activity of ABCB1 protein]	17526808
D014700	Verapamil	Verapamil inhibits the reaction [Methoxsalen results in decreased activity of ABCB1 protein]	29079042
D014700	Verapamil	Verapamil inhibits the reaction [[Methoxsalen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of Daunorubicin]	29079042
D014700	Verapamil	Verapamil inhibits the reaction [Verapamil analog results in increased activity of ABCB1 protein mutant form]	12711602
D014700	Verapamil	Verapamil promotes the reaction [ABCB1 protein mutant form binds to 8-azidoadenosine 5'-triphosphate]	11027628
D014700	Verapamil	Verapamil promotes the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]	21783720
D014700	Verapamil	Verapamil promotes the reaction [propiconazole results in decreased activity of ABCB1 protein]	21783720
D014700	Verapamil	Verapamil results in decreased activity of ABCB1 protein	10571255; 10997946; 11836167; 12387747; 15451006; 15627040; 15725475; 16049968; 18408562; 19070657; 19505989; 19528478; 19944135; 20457140; 21783720; 24446304; 28669723;
D014700	Verapamil	[Verapamil results in decreased activity of ABCB1 protein] which results in decreased export of Topotecan	20457140
D014700	Verapamil	[Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylaconine	23200901
D014700	Verapamil	[Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylhypaconine	23200901
D014700	Verapamil	[Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylmesaconine	23200901
D014700	Verapamil	[Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of Digoxin	10997946
D014700	Verapamil	[Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of hypaconitine	23200901
D014700	Verapamil	[Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of mesaconitine	23200901
D014700	Verapamil	[Verapamil results in decreased activity of ABCB1 protein] which results in increased susceptibility to Doxorubicin	10571255
D014700	Verapamil	[Verapamil results in decreased activity of ABCB1 protein] which results in increased susceptibility to Paclitaxel	18673531
D014700	Verapamil	[Verapamil results in decreased activity of ABCB1 protein] which results in increased uptake of fluorexon	10571255
D014700	Verapamil	Verapamil results in decreased expression of ABCB1 protein	22079615
D014700	Verapamil	Verapamil results in increased activity of ABCB1 protein	23273999; 2900677; 29625142;
D014700	Verapamil	Verapamil results in increased expression of ABCB1 mRNA	15276086; 7476894;
D014700	Verapamil	Vinblastine inhibits the reaction [Verapamil analog results in increased activity of ABCB1 protein mutant form]	12711602
D014700	Verapamil	[Verapamil results in decreased expression of ABCB1] promotes the reaction [Doxorubicin results in increased activity of CASP3 protein]	15861398
D014700	Verapamil	[Verapamil results in decreased expression of ABCB1] promotes the reaction [Doxorubicin results in increased activity of CASP7 protein]	15861398
D014700	Verapamil	Verapamil results in decreased activity of ABCB1 protein	11408081
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 results in decreased uptake of Digoxin]	20557448
D014700	Verapamil	Verapamil results in decreased activity of ABCB1 protein	16026006
D014700	Verapamil	Verapamil inhibits the reaction [ABCB1 results in decreased susceptibility to Cadmium Chloride]	10636889
D014700	Verapamil	Verapamil results in increased activity of ABCB1 protein	16033948
D014700	Verapamil	ABCB1 protein results in increased susceptibility to Verapamil	21657271
D014700	Verapamil	Verapamil binds to ABCB1 protein	10783826
D014700	Verapamil	Verapamil inhibits the reaction [[ABCB1 protein co-treated with MGMT protein mutant form] results in decreased susceptibility to Etoposide]	16733832
D014700	Verapamil	Verapamil metabolite binds to ABCB1 protein	10783826
D014700	Verapamil	Verapamil results in decreased activity of ABCB1 protein	11724091; 23200901; 23562926;
C059141	verlukast	verlukast results in decreased activity of ABCB1 protein	16316932
D014747	Vinblastine	ABCB1 protein affects the uptake of Vinblastine	15640379
D014747	Vinblastine	ABCB1 protein results in decreased susceptibility to Vinblastine	11355955; 15725475; 17284363; 26689174; 8917702; 9148857;
D014747	Vinblastine	ABCB1 protein results in increased secretion of Vinblastine	12235267
D014747	Vinblastine	ABCB1 protein results in increased transport of Vinblastine	12708479; 16221533; 23976943;
D014747	Vinblastine	Amiodarone inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]	12235267
D014747	Vinblastine	Carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Vinblastine]	12708479
D014747	Vinblastine	[Carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Vinblastine]] which results in decreased susceptibility to Vinblastine	12708479
D014747	Vinblastine	Clotrimazole inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]	12235267
D014747	Vinblastine	cnidiadin inhibits the reaction [ABCB1 protein results in increased export of Vinblastine]	15824923
D014747	Vinblastine	Curcumin analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vinblastine]	26689174
D014747	Vinblastine	Curcumin inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vinblastine]	26689174
D014747	Vinblastine	Cyclosporine inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]	12235267
D014747	Vinblastine	Diazinon affects the reaction [ABCB1 protein results in increased transport of Vinblastine]	16221533
D014747	Vinblastine	[Elacridar binds to and results in decreased activity of ABCB1 protein] which results in decreased export of Vinblastine	23976943
D014747	Vinblastine	Erythromycin inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]	12235267
D014747	Vinblastine	Ketoconazole inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]	12235267
D014747	Vinblastine	Miconazole inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]	12235267
D014747	Vinblastine	NR1I2 protein promotes the reaction [Vinblastine results in increased expression of ABCB1 protein]	20041327
D014747	Vinblastine	Reserpine inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]	12235267
D014747	Vinblastine	Sesquiterpenes analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vinblastine]	15466210
D014747	Vinblastine	[sodium arsenite results in increased expression of ABCB1 protein] which results in decreased susceptibility to Vinblastine	1967174
D014747	Vinblastine	Troleandomycin inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]	12235267
D014747	Vinblastine	Verapamil inhibits the reaction [ABCB1 protein affects the uptake of Vinblastine]	15640379
D014747	Vinblastine	Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Vinblastine]	12708479
D014747	Vinblastine	Vinblastine binds to ABCB1 protein	23976943
D014747	Vinblastine	Vinblastine inhibits the reaction [Verapamil analog results in increased activity of ABCB1 protein mutant form]	12711602
D014747	Vinblastine	Vinblastine results in increased activity of ABCB1 protein mutant form	12711602
D014747	Vinblastine	[Vinblastine results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA	20041327
D014747	Vinblastine	Vinblastine results in increased expression of ABCB1 protein	20041327
D014747	Vinblastine	Vinblastine results in decreased activity of ABCB1 protein	11408081
D014747	Vinblastine	Vinblastine results in increased expression of ABCB1 mRNA	19501419
D014747	Vinblastine	ABCB1 protein results in decreased susceptibility to Vinblastine	11455017
D014748	Vinca Alkaloids	[cnidiadin results in decreased activity of ABCB1 protein] which results in increased susceptibility to Vinca Alkaloids	15824923
D014750	Vincristine	ABCB1 protein affects the susceptibility to Vincristine	24975508
D014750	Vincristine	ABCB1 protein results in increased export of Vincristine	28093773
D014750	Vincristine	valspodar inhibits the reaction [ABCB1 protein affects the susceptibility to Vincristine]	24975508
D014750	Vincristine	ABCB1 protein affects the susceptibility to Vincristine	15645438
D014750	Vincristine	ABCB1 protein affects the uptake of Vincristine	11934808
D014750	Vincristine	ABCB1 protein results in decreased susceptibility to Vincristine	21344920; 25058526; 7905786;
D014750	Vincristine	ABCB1 protein results in decreased uptake of Vincristine	10617675
D014750	Vincristine	ABCB1 protein results in increased transport of Vincristine	16316932
D014750	Vincristine	CEP 33779 inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]	25058526
D014750	Vincristine	Cyclosporine inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]	7905786
D014750	Vincristine	[Estradiol results in decreased expression of ABCB1 protein] which results in increased uptake of and results in increased susceptibility to Vincristine	16925584
D014750	Vincristine	Fenofibrate inhibits the reaction [ABCB1 protein results in increased transport of Vincristine]	16316932
D014750	Vincristine	Flupenthixol analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]	7905786
D014750	Vincristine	[MGMT protein co-treated with ABCB1 protein] results in decreased susceptibility to Vincristine	11792417
D014750	Vincristine	NR1I2 protein promotes the reaction [Vincristine results in increased expression of ABCB1 protein]	20041327
D014750	Vincristine	[Paclitaxel results in increased expression of ABCB1] which results in decreased susceptibility to Vincristine	21833476
D014750	Vincristine	Verapamil inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]	25058526
D014750	Vincristine	[Vincristine results in decreased susceptibility to Vincristine] which affects the expression of ABCB1 mRNA	19944135
D014750	Vincristine	[Vincristine results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA	20041327
D014750	Vincristine	Vincristine results in increased expression of ABCB1 protein	15239124; 16038730; 20041327;
D014750	Vincristine	zosuquidar trihydrochloride inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]	21344920
D014750	Vincristine	ABCB1 results in decreased susceptibility to Vincristine	18310528
D014801	Vitamin A	6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in decreased expression of ABCB1 mRNA]	15327746
D014801	Vitamin A	Mannitol inhibits the reaction [Vitamin A results in decreased expression of ABCB1 mRNA]	15327746
D014801	Vitamin A	Vitamin A results in decreased expression of ABCB1 mRNA	15327746
D014805	Vitamin B 12	Vitamin B 12 inhibits the reaction [Methotrexate results in increased expression of ABCB1 mRNA]	17982279
D014805	Vitamin B 12	Vitamin B 12 results in decreased expression of ABCB1 mRNA	17982279
D014805	Vitamin B 12	Vitamin B 12 results in decreased expression of ABCB1 protein	17982279
D000077337	Vorinostat	[Vorinostat co-treated with Isotretinoin] results in increased expression of ABCB1 mRNA	18769122
D014859	Warfarin	ABCB1 polymorphism affects the susceptibility to Warfarin	24092646; 25312789;
D014859	Warfarin	ABCB1 protein affects the metabolism of Warfarin	21797966
C009684	withaferin A	withaferin A inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]	20438634; 20438634;
D014966	Xanthenes	ABCB1 protein results in increased export of Xanthenes	25862123
D014966	Xanthenes	ABCB1 protein results in increased transport of Xanthenes	21436125
D014966	Xanthenes	Calcium deficiency inhibits the reaction [ABCB1 protein results in increased export of Xanthenes]	25862123
D014966	Xanthenes	[valspodar results in decreased activity of ABCB1 protein] which results in decreased transport of Xanthenes	21436125
D014966	Xanthenes	Xanthenes results in decreased activity of ABCB1 protein	18686201; 20041016;
D015016	Yohimbine	Yohimbine analog results in increased expression of ABCB1 mRNA	7476894
D015025	Zearalenone	Zearalenone results in increased expression of ABCB1 mRNA	20607812
D015215	Zidovudine	Zidovudine results in increased expression of ABCB1 mRNA	15456083; 18310046; 24292225;
D015215	Zidovudine	Zidovudine results in increased expression of ABCB1 protein	9148857
D015032	Zinc	Zinc results in increased expression of ABCB1 protein	15084411
D015032	Zinc	Zinc inhibits the reaction [Magnesium results in increased activity of ABCB1 protein]	2900677
C016837	zinc chloride	zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ABCB1 mRNA]	19714248
C016837	zinc chloride	zinc chloride inhibits the reaction [Doxorubicin results in increased expression of ABCB1 mRNA]	19714248
C095179	zosuquidar trihydrochloride	ABCB1 protein affects the reaction [zosuquidar trihydrochloride results in decreased transport of calcein AM]	30217652
C095179	zosuquidar trihydrochloride	zosuquidar trihydrochloride analog inhibits the reaction [ABCB1 protein results in increased susceptibility to NSC73306]	21721528
C095179	zosuquidar trihydrochloride	zosuquidar trihydrochloride inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]	21344920
C095179	zosuquidar trihydrochloride	zosuquidar trihydrochloride results in decreased activity of ABCB1 protein	27499331
C095179	zosuquidar trihydrochloride	[zosuquidar trihydrochloride results in decreased activity of ABCB1 protein] which results in decreased transport of N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide	24321342
C095179	zosuquidar trihydrochloride	[zosuquidar trihydrochloride results in decreased activity of ABCB1 protein] which results in decreased transport of omadacycline	27499331
C095179	zosuquidar trihydrochloride	zosuquidar trihydrochloride results in decreased activity of ABCB1 protein	24321342

Functional annotations

Keywords

Keyword ID	Keyword Term
KW-0002	3D-structure
KW-0025	Alternative splicing
KW-0067	ATP-binding
KW-1003	Cell membrane
KW-0325	Glycoprotein
KW-0472	Membrane
KW-0547	Nucleotide-binding
KW-0597	Phosphoprotein
KW-0621	Polymorphism
KW-1185	Reference proteome
KW-0677	Repeat
KW-1278	Translocase
KW-0812	Transmembrane
KW-1133	Transmembrane helix
KW-0813	Transport

Interpro

InterPro ID	InterPro Term
IPR003593	AAA+_ATPase
IPR011527	ABC1_TM_dom
IPR036640	ABC1_TM_sf
IPR003439	ABC_transporter-like
IPR017871	ABC_transporter_CS
IPR030258	MDR1
IPR027417	P-loop_NTPase
IPR039421	Type_I_exporter

PROSITE

PROSITE ID	PROSITE Term
PS50929	ABC_TM1F
PS00211	ABC_TRANSPORTER_1
PS50893	ABC_TRANSPORTER_2

Pfam

Pfam ID	Pfam Term
PF00664	ABC_membrane
PF00005	ABC_tran

Gene: ABCB1

Basic information

Gene expression information

Gene expression in different tissues (GTEx V7)

Gene expression in different tissues (ENCODE)

Protein structural annotations

3D structure in PDB database

Protein disorder information

Orthologous information

Identified variants/mutations related to cleft phenotype

Other genetic variants/mutations

Disease or phenotype associated information

Gene Ontology (GO)/biological pathways

GO:Molecular Function

GO:Biological Process

GO:Cellular Component

Reactome Pathway

Drugs and compounds information

Functional annotations

Keywords

Interpro

PROSITE

Pfam

Protein-protein interaction

Protein-miRNA interaction