Gene: ABCB1

Basic information

Tag Content
Uniprot ID G1T8H8
Entrez ID 100008914
Genbank protein ID
Genbank nucleotide ID XM_008261791.2
Ensembl protein ID ENSOCUP00000012879
Ensembl nucleotide ID ENSOCUG00000014981
Gene name Uncharacterized protein
Gene symbol ABCB1
Organism Oryctolagus cuniculus
NCBI taxa ID 9986
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MDIEGERNGR LGKNMYKLNK RNKKEKEKRP TVSAFAMFRY SNWLDKLYMV VGTLAAIIHG 60
AALPLMMLVF GDMTDSFSNP GNMIPANITN LNMSNISASE IYKHLEEEMT TYAYYYSGIG 120
AGVLVAAYIQ VSFWCLAAGR QTFKIRKQFF HSIMRQEIGW FDVHDVGELN TRLTDDVSKI 180
NDGIGDKIGM FFQSMSTFFT GFIVGFTRGW KLTLVILAIS PVLGLSAALW AKIMSSFTDK 240
ELLAYAKAGA VAEEVLAAIR TVIAFGGQQK ELERYNKNLE EAKRIGIKKA ITANISVGVA 300
FLLMYASYAL AFWYGTTLVI SKEYSIGQVL TVFFSVLVGA FSIGQASPNV EAFANARGAA 360
YEIFRIIDNK PSIDSYSEAG HKPDNIKGNL EFRNVHFSYP SRKEVKILKG LNLKVESGQT 420
VALVGNSGCG KSTTVQLMQR LYDPTDGVVS IDGQDIRTMN VRYLREITGV VSQEPVLFAT 480
TIAENIRYGR EDVTMDEIEK AVKEANAYNF IMKLPHKFDT LVGERGAQLS GGQKQRIAIA 540
RALVRNPKIL LLDEATSALD TESEAVVQVA LDKARKGRTT IVIAHRLSTV RNADVIAGFD 600
NGVIVERGNH EELMRQKGVY FRLVTMQTAG NEIDLENSAS ESRGEKMDLV EMSAKESGSS 660
LIRRRSSHKS FHGAQGQDGK LSTTEAQNEN VPPVSFWRIM KLNLTEWPYF LVGVICAIIN 720
GGLQPAFAVV FSKIVGVFTR NDDDETKRRN SDLFSLLFLI LGIISFITFF LQGFTFGKAG 780
EILTKRLRYM VFKSMLRQDV SWFDDPKNTT GALTTRLAND AAQVKGATGS RLAVIAQNIA 840
NLGTGIIISL VYGWQLTLLL LAIVPIIAIA GVVEMKMLSG QALKDKKELE GSGKIATEAI 900
ENFRTVVSLT REQKFENMYA QSLQVPYRNS LKKAHIFGIT FSFTQAMMYF SYAGCFRFGA 960
FLVARELMSF ENVLLVFSAV VFGAMAVGQV SSFAPDYAKA KISASHIIMI LEKLPKIDSY 1020
STEGLKLGTL EGNMTFKDVV FNYPTRPDIP VLQGLNLQVK KGQTLALVGP SGCGKSTVVQ 1080
LIERFYDPLA GTVLLDGKEV NQLNVQWLRA HLGIVSQEPI LFDCSIAENI AYGDNSRVVS 1140
QDEIIKAAKE ANIHAFIDSL PDKYNTRVGD KGTQLSGGQK QRIAIARALV RQPHILLLDE 1200
ATSALDTESE KVVQEALDKA REGRTCVVIA HRLSTIQNAD MIVVFQNGRV KECGTHHQLL 1260
AQKGIYFSMV SVQAGGKRQ 1279

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologABCB1403879Q4PLA8Canis lupus familiarisPredictionMore>>
1:1 orthologABCB15243P08183Homo sapiensPublicationMore>>
1:1 orthologAbcb1a18671P21447Mus musculusPredictionMore>>
1:1 orthologABCB1A0A2I3RUL7Pan troglodytesPredictionMore>>
1:1 orthologABCB1100008914G1T8H8Oryctolagus cuniculusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0016021 integral component of membrane
GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0042626 ATPase-coupled transmembrane transporter activity

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR030258 MDR1
IPR027417 P-loop_NTPase
IPR039421 Type_I_exporter

PROSITE

PROSITE ID PROSITE Term
PS50929 ABC_TM1F
PS00211 ABC_TRANSPORTER_1
PS50893 ABC_TRANSPORTER_2

Pfam

Pfam ID Pfam Term
PF00664 ABC_membrane
PF00005 ABC_tran