| Tag | Content |
|---|---|
| Uniprot ID | A0A2I3RWX9 |
| Entrez ID | 464863 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_016962141.1; XM_016962142.1; |
| Ensembl protein ID | ENSPTRP00000068820 |
| Ensembl nucleotide ID | ENSPTRG00000050333 |
| Gene name | Protein transport protein sec16 |
| Gene symbol | SEC16A |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. |
| Sequence | MQPPPQAVPS GMAGPPPAGN PRSVFWASSP YRRRANNNAA MAPTTCPLQP VTDPFAFSRQ 60 ALQSTPLGSS SKSSPPVLQG PAPAGFSQHP GLLVPHTHAR DSSQGPCEPL PGPLTQPRAD 120 ASPFSGALTP SAPPGPEMNR SAEVGPSSEP EVQTLPYLPH YIPGVDPEMS HGGHPHGNMP 180 GLDRPLSRQN PHDGVVTPAA SPSLPQPRLQ MPGQWGPVQG GPQPSGQHRS PCPEGPVPSG 240 VPCATSVPHF PTPSILHQGP GHEQHSPLVA PPAALPSDGR DEVGHLQSGS HLANNFDPEN 300 TFRQNPRIVN HWASPELRQN PGVKNEHRPA SALVNPLAQG DSPENRTHHP LGAGARSGCA 360 PLEADSGASG ALAMFFQGGE TENEENLSSE KAGLSGQADF DDFCSSPGLG RPPAPAHMGA 420 GSLCQALLPG PSNEAAGDVW GDAASTGVPD ASGSQYENVE NLEFVQNQEV LPSEPLNLDP 480 SSPSDQFRYG PLPGPAVPRH GAVCHTGAPD ATLHTVHPDS VSSSYSSRSH GRLSGSARPQ 540 ELVGTFIQQE VGKPEDEASG SFFKQIDSSP VGGETDETTV SQNYRGSVSQ PSTPSPPKPT 600 GIFQTSANSS FEPVKSHLVG VKPFEADRAN VVGEVRETCV RQKQCRPAAA LPDASPGNLE 660 QPPDNMETLC APQVCPLPLN STTEAVHMLP HAGAPPLDTV YPAPEKRPSA RAQGPVKCES 720 PATTLWAQSE LPDFGGNVLL APAAPALYVC AKPQPPEVVQ PPEEAMSGQQ SRNPSSAAPV 780 QSRGGIGASE NLENPPKMGE EEALQSQASS GYASLLSSPP TESLQNPPVL IAQPDHSYNL 840 AQPINFSVSL PNSHEKNQSW REALVGDRPA VSSWALGGDS GENTSLSGIP TSSVLSLSLP 900 SSVAQSNFPQ GSGASEMVPN QPANLLVRPP SQPVPENLVP ESQKDRKAGS ALPGFANSPA 960 GSTSVVLVPP AHGTLVPDGN KANHSSHQED TYGALDFTLS RTLENPVSMY NPSHSDSLAS 1020 QQSVASHPRQ SGPGAPNLDR FYQQVTKDAQ GQPGLERAQQ ELVPPQQQAS PPQLPKATFS 1080 ELSNPESLPA QGQAQNSAQS PASLVPVDAG QQLPPRPPQS SSVSLVSSGS GQAAVPSEQP 1140 WPQPVPALAP GPPPPDLAAY YYYRPLYDAY QPQYSLPYPP EPGAASLYYQ DVYSLYEPRY 1200 RPYDSAASAY AENYRYPEPE RPSSRASHSS ERPPPRQGYP EGYYSSKSGW SSQSDYYASY 1260 YSSQYDYGDP GHWDRYHYSA RVRDPRTYDR RYWCDAEYDA YRREHSAFGD RPEKRDNNWR 1320 YDPRFTGSFD DDPDPHRDPY GEEVDRRSLH SEHSARSLHS AHSLASRRSS LSSHSHQSQI 1380 YRSHNVAAGS YEAPLPPGSF HGDFAYGTYR SNFSSGPGFP EYGYPADTVW PAMEQVSSRP 1440 TSPEKFSVPH VCARFGPGGQ LIKVIPNLPS EGQPALVEVH SMEALLQHTS EQEEMRAFPG 1500 PLAKDDTHKV DVINFAQNKA MRCLQNENLI DKESASLLWN FIVLLCRQNG TVVGTDIAEL 1560 LLRDHRTVWL PGKSPNEANL IDFTNEAVEQ VEEEESGEAQ LSFLTGGPAA AASSLERETE 1620 RFRELLLYGR KKDALESAMK NGLWGHALLL ASKMDSRTHA RVMTRFANSL PINDPLQTVY 1680 QLMSGRMPAA STCCGDEKWG DWRPHLAMVL SNLNNNMDVE SRTMATMGDT LASRGLLDAA 1740 HFCYLMAQAG FGVYTKKTTK LVLIGSNHSL PFLKFATNEA IQRTEAYEYA QSLGAQTCPL 1800 PSFQVFKFIY SCRLAEMGLA TQAFHYCEAI AKSILTQPHL YSPVLISQLV QMASQLRLFD 1860 PQLKEKPEEE SLAAPTWLVH LQQVERQIKE GAGVWHQDGA LPQQCPSTPS SEVEQLDGPG 1920 LSQPAALGIA NPLLAVPAPS PEHSSPSVRL LPSAPQTLPD GPLASPARVP MFPVPLPPGP 1980 LEPGPGCVTP GPALGFPEPS RPGLPPGVPP LQERRHLLQE ARSPDPGIVP QEAPVGNSLS 2040 ELSEENFDGK FANLTPSRTM PDSEAPPGWD RADSGPTQPP LSFSPAPETK RPGQAAKKET 2100 KEPKKGESWF FRWLPGKKKT EAYLPDDKNK SIVWDEKKNQ WVNLNEPEEE KKAPPPPPTS 2160 MPKTVQAAPP ALPGPPGAPV NMYSRRAAGT RARYVDVLNP SGTQRSEPAL APADFVAPLA 2220 PLPIPSNLFV PTPVSSVRPQ GRSGRNDGLL TLSSPDAEEP QLPDRTGREG PAAARGLANP 2280 EPAPEPKAPG DLPAAGGPPS GAVPFYNPAQ LAQACATSGS SRLGRIGQRK HLVLN 2335 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | SEC16A | 519689 | F1N6K7 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | SEC16A | 102172363 | A0A452FDB3 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | SEC16A | 9919 | O15027 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Sec16a | 227648 | E9QAT4 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | SEC16A | 464863 | A0A2I3RWX9 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Sec16a | 100360302 | D3ZN76 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005783 | endoplasmic reticulum |
| GO:0000139 | Golgi membrane |
| GO:0048208 | COPII vesicle coating |
| GO:0015031 | protein transport |