| Tag | Content |
|---|---|
| Uniprot ID | A0A452FDB3 |
| Entrez ID | 102172363 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018056122.1 |
| Ensembl protein ID | ENSCHIP00000022256 |
| Ensembl nucleotide ID | ENSCHIG00000020286 |
| Gene name | Protein transport protein sec16 |
| Gene symbol | SEC16A |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. |
| Sequence | MQPPPQAVPS GVVGPPPSGS PQTMFWSNSP YRRQAGSHTP MAPITCPLQP VTDPFAFSRQ 60 ALQSTSLGGS SKSSPPILQG PPPPSSLQRA GLPVPHTNTG DSSQGPCEPL PGPPVQPRAD 120 ASPFPGAPMP SASHGPETNR SAKAPGPEPE LPNPPYPPQY IPAVGSSGSR GGLPQGHVPR 180 PDRPLSRPSP PDSAAPPAAL PLPPQPCQQV PGQWGPGQGG PRPPGQQYWP GPEGPPQVPG 240 PHASSVTHFP PLSSLHQHPG HEQLGPPASL PGPSASDGRN EAVCLPSGDH SANSFDPESA 300 FRQNSRVGNA RANQELRSSP GVNREQLSGL AAVSPLAQGN GLESHSHCSP GAGGAWTPLE 360 AGSGALAMFF KGGETENEEN LSLETAGSAG QADVDGFCLG QLPAHVGAGG AHQAFPRGSS 420 SEPTQLGGEP QPYFPQSAGS PHEKAASKVA TVDVWADTAR AGAQYENVEN LEFVQNQEVL 480 PSEPLSMDPS SPGDPLRCGP LPGPAGPRLG AVGPVGGGGL NLEALDMTTR PARSDSVSSG 540 YSGKSHRGLP GARLRDSGTF IQQEVGKPED ESPGRFFKQI DSSPVGGETD ETSSQNYLGS 600 LSQPSTPSPP KPTGLFQTSA NSSFEPVKSH LVGVKPVEAD RANVVGEVRG PSARQQHRAA 660 AATPDAAPGN LEQPPDNMET LFPPQRCVPP LATPLEAGRG LLQATGPPLE TVLPTPEKRP 720 STRVQGPVKC ESPATTLWAQ NELPDFGGNV LLAPAAPALH VPVKPQLSEV IQPPDEGAAR 780 QVGSGGQSGD GLGASENLEN PPQLGEEEAL PPQAGPSYAS LLSSPPAESL QNQPILIAQP 840 DQGYSLAQPV NVSLSLPNPN EKAPSWRDSS VGDKPIVSGR AAGGDPGESA PLSGMPASSL 900 ICSPLPNHLA QSPFPQVSST YDMVSNQAAN LLVQPHSHPN ALLPEGQKVH SAESVPPEEV 960 PSPAGGAGLV LVPPASSTSL PDNSKPGLCG RRDGASGALD FMFGRALENP AGVYSLAHVD 1020 GPASVQPPAA SRQPPGPGAN TPDRFYQQVM KEAHDQPGAE RAQQELALPL PAPQGPRAVL 1080 PEPSNPGSPP VQAQPADPAR PASPAAADAG QQLLPRPPRS SSASVVSTSS GQAALRPDQQ 1140 WLQPPPPDLA SYFYYRPLYD GYQPPYPYSA YPPDPGPAPH YYQDIYGLYD PRYRPCDSAA 1200 YMDPCRYPEP ERPSSRASHC SDRPAARQAY PEGYYNSKSG WSSQSDYYAG CYSSQYDYRD 1260 PGRWDRLYYS SRFRDPRSYD RRYWYDAEYD SCRKESYACG DRPEKYDDRY RYDPRFTGSF 1320 DDEPEPPRDP YGEEADRRSE HSEHSARSLR SAPSLQSRRS SFSAHSQQSQ VYRSHNVPSG 1380 SYEVPPPPGS FHGDYAYGPY VSDFHGAPGF PEYGYPTEAS WPSVEQAPSR PSSPEKFSVP 1440 HVCARFGPGG QLIKVIPNLP SEGQPALVEI HSMETLLQHT PEQEEMRAFP GPLGKDDTHK 1500 VDVINFAQNK ATKCLQNENL IDKESASLLW SFIVLLCRQN GTVVGTDIAE LLLRDHRTVW 1560 LPGKSPNEAN LIDFTNEAME QVEEEESGEA QLSFLTDSQA ASTLEKDTER FRELLLYGRK 1620 KDALESAMKS GLWGHALLLA SKMDSRTHAR VMTRFANSLP INDPLQTVYQ LMSGRMPAAS 1680 TCCGDEKWGD WRPHLAMILS NLSSNVDVES RAVAAMGDTL ASKGLLDAAH FCYLMAQVGF 1740 GVYTKKTTKL VLIGSNHSLP FSKFATNEAI QRTEAYEYAQ SLGAQACSPP SFQVFKFIYC 1800 CRLAEMGLAA QAFHYCEAIA KSVLAQPHRH SPVLLRQLVQ VASQLRLFDP QLKEKPEEEA 1860 SAEPAWLVQL QLVERRVEEG AVAWSQDGAC PQRCPSSPSP EVGPRDGPGP SQPAGLGADN 1920 PLLAPPVPST KLFSQDVRQL PSAPSALPAG PAAIPAQVPM FPVPLPAPVE LEPVHGPPGA 1980 VPGFQEPSGP DPVALYPGPG VPPLQETDCL FPEARSQDAG AVPQETPGRS SLSEPGEEEF 2040 GGSFANMGSF RTSPGSEAPL QALQPPAPLT PAPEVQRPVQ ATKKESKEPK KSSESWFSRW 2100 LPVKKRTEAY LPDDKNKSIV WDEKKNRWVD VNEPEEEKKA PPPPPTALPK APQAAHPGPG 2160 GPPRPTVNIY SRKAAGTRAR YVDVLNPGGP QRSEPTLAPT DLFAPLAPLP IPAHLLGPNA 2220 DAEEVPSAEA ASREGPARPE PASDPKVFGP AVALLPGPEL PASGLDGPQG GEAPGALTPA 2280 GAPPGAGVPF YNPAQFAQAP AASGSSRTGR IGQRKYPALS |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | SEC16A | 519689 | F1N6K7 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | SEC16A | 102172363 | A0A452FDB3 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | SEC16A | 9919 | O15027 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Sec16a | 227648 | E9QAT4 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | SEC16A | 464863 | A0A2I3RWX9 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Sec16a | 100360302 | D3ZN76 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005783 | endoplasmic reticulum |
| GO:0000139 | Golgi membrane |
| GO:0048208 | COPII vesicle coating |
| GO:0015031 | protein transport |