Gene: PHF8

Basic information

Tag Content
Uniprot ID A0A2I3SKZ5; A0A2J8J9T1;
Entrez ID 465652
Genbank protein ID
Genbank nucleotide ID XM_016943261.1
Ensembl protein ID ENSPTRP00000077169
Ensembl nucleotide ID ENSPTRG00000021932
Gene name PHD finger protein 8
Gene symbol PHF8
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MASVPVYCLC RLPYDVTRFM IECDMCQDWF HGSCVGVEEE KAADIDLYHC PNCEVLHGPS 60
IMKKRRGSSK GHDTHKGKPV KTGSPTFVRE LRSRTFDSSD EVILKPTGNQ LTVEFLEENS 120
FSVPILVLKK DGLGMTLPSP SFTVRDVEHY VGSDKEIDVI DVTRQADCKM KLGDFVKYYY 180
SGKREKVLNV ISLEFSDTRL SNLVETPKIV RKLSWVENLW PEECVFERPN VQKYCLMSVR 240
DSYTDFHIDF GGTSVWYHVL KGEKIFYLIR PTNANLTLFE CWSSSSNQNE MFFGDQVDKC 300
YKCSVKQGQT LFIPTGWIHA VLTPVDCLAF GGNFLHSLNI EMQLKAYEIE KRLSTADLFR 360
FPNFETICWY VGKHILDIFR GLRENRRHPA SYLVHGGKAL NLAFRAWTRK EALPDHEDEI 420
PETVRTVQLI KDLAREIRLV EFNITGACLN DSDDDSPDLD LDGDESPLAL LMSNGSTKRV 480
KSLSKSRRTK IAKKVDKARL MAEQVMEDEF DLDSDDELQI DERLGKEKAT LIIRPKFPRK 540
LPRAKPCSDP NRVREPGEVE FDIEEDYTTD EDMVEGVEGK LGNGSGAGGI LDLLKASRQV 600
GGPDYAALTE APASPSTQEA IQGMLCMANL QSSSSSPATS SLQAWWTGGQ DRSSGSSSSG 660
LGTVSNSPAS QRTPGKRPIK RPAYWRTESE EEEENASLDE QDSLGACFKD AEYIYPSLES 720
DDDDPALKSR PKKKKNSDDA PWSPKARVTP TLPKQDRPVR EGTRVASIET GLAAAAAKLA 780
QQELQKAQKK KYIKKKPLLK EVEQPRPQDS NLSLTVPAPT VAATPQLVTS SSPLPPPEPK 840
QEALSGSLAD HEYTARPNAF GMAQANRSTT PMAPGVFLTQ RRPSVGSQSN QAGQGKRPKK 900
GLATAKQRLG RILKIHRNGK LLLRQVIVQA ECRQAIHEPK LKRRDAHP 948

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologPHF8A0A452DKR2Capra hircusPredictionMore>>
1:1 orthologPHF823133Q9UPP1CPO,CL/PHomo sapiensPublicationMore>>
1:1 orthologPhf8320595Q80TJ7Mus musculusPredictionMore>>
1:1 orthologPHF8465652A0A2I3SKZ5Pan troglodytesPredictionMore>>
1:1 orthologPHF8100520413A0A287B7U8Sus scrofaPredictionMore>>
1:1 orthologPHF8100344764G1SHZ3Oryctolagus cuniculusPredictionMore>>
1:1 orthologPhf8317425D4AD31Rattus norvegicusPredictionMore>>
1:1 orthologphf8566534P0CH95Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0046872 metal ion binding

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0479 Metal-binding
KW-0539 Nucleus
KW-1185 Reference proteome
KW-0862 Zinc
KW-0863 Zinc-finger

Interpro

InterPro ID InterPro Term
IPR041070 JHD
IPR003347 JmjC_dom
IPR019786 Zinc_finger_PHD-type_CS
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger

PROSITE

PROSITE ID PROSITE Term
PS51184 JMJC
PS01359 ZF_PHD_1
PS50016 ZF_PHD_2

Pfam

Pfam ID Pfam Term
PF17811 JHD
PF02373 JmjC
PF00628 PHD