Gene: ADAMTS20

Basic information

Tag Content
Uniprot ID A0A2I3SSY2
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSPTRP00000080052
Ensembl nucleotide ID ENSPTRG00000004841
Gene name ADAM metallopeptidase with thrombospondin type 1 motif 20
Gene symbol ADAMTS20
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MWVAKWLTGL LYHLSLFVTR SWEVHFHPRQ EALVRTLTSY EVVIPERVNE FGEVFPQSHH 60
FSRQKRSSEA LEPMPFRTHY RFTAYGQLFQ LNLTADASFL AAGYTEVHLG TPERGAWESD 120
AGPSDLRHCF YRGQVNSQED YKAVVSLCGG LTGTFKGQNG EYFLEPIMKA DGNEYEDGHN 180
KPHLIYRQEL NNSFLQTLKY CNVSESQIKE TSLPFHTYSN MNEDLNVMKE RVLGHTSKNV 240
PLKDERSQLH SRKKRLISYP RYIEIMVTAD AKVVSAHGSN LQNYILTLMS IVATIYKDPS 300
IGNLIHIVVV KLVMIHCEEE GPVINFDGAT TLKNFCSWQQ TQNDLDDVHP SHHDTAVLIT 360
REDICSSKEK CNMLGLSYLG TICDPLQSCF INEEKGLISA FTIAHELGHT LGVQHDDSPR 420
CKEMKVTQYH VMAPALSFHM SPWSWSNCSR KYVTEFLDTG YGECLLDKPD EEIYNLPSEL 480
PGSRYDGNKQ CELAFGPGSQ MCPHINICMH LWCTSTEKLH KGCFTQHVPP ADGTDCGPGM 540
HCRHGLCVNK ETETRPVNGE WGPWEPYSSC SRTCGGGIES ATRRCNRPEP RNGGNYCVGR 600
RMKFRSCNTD SCPKGTQDFR EKQCSDFNGK HLDISGIPSN VRWLPRYSGI GTKDRCKLYC 660
QVAGTNYFYL LKDMVEDGTP CGTETHDICV QGHHSYNIDC NCVLKAAGCD HVLNSSAKID 720
KCGVCGGDNS SCKTITGVFN SSHYGYNVVV KIPAGATNVD IRQYSYSGQP DDSYLALSDA 780
EGNFLFNGNF LLSTSKKEIN VQGTRTVIEY SGSNNAVERI NSTNRQEKEL ILQVLCVGNL 840
YNPDVHYSFN IPLEERSDMF TWDPYGPWEG CTKMCQGLQR RNITCIHKSD HSVVSDKECD 900
HLPLPSFVTQ SCNTDCELRW HVIGKSECSS QCGQGYRTLD IHCMKYSIHE GQTVQVDDHY 960
CGDQLKPPTR ELCHGNCVFT RWHYSEWSQC SRSCGGGERS RESYCMNNFG HRLADNECQE 1020
LSRVTRENCN EFSCPSWAAS EWSELDVVTH TCGPSYSGVI TLTEQSCVLT PCSFISKLET 1080
ALLPTVLIKK MAQWRHGSWT PCSVSCGRGT QARYVSCRDA LDRIADESYC AHLPRPAEIW 1140
DCFTPCGEWQ AGDWSPCSAS CGHGKTTRQV LCMNYHQPID ENYCDPEVRP LMEQECSLAA 1200
CPTAHSHFPS SPVQPSYYLS TNLPLTHKLE DNENQVVHPS VRGNQWRTGP WGSCSSSCSG 1260
GLQRRAVVCQ DENGQSASYC DAASKPPELQ HCGPGPCPQW NYGNWGECSQ TCGGGIKSRL 1320
VICQFPNGQI LEDHNCEIVN KPPSVIQCHM HACPADVSWH QEPWTSEDLK VKLLPQRTII 1380
LWELMKNIFC HGKHSHMYLI NVITDHLLYP RHCDPETIET YFLSLWSLQF TWGDLKYYKN 1440
SL 1442

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologADAMTS20536137E1B900Bos taurusPredictionMore>>
1:1 orthologADAMTS20A0A452GAZ8Capra hircusPredictionMore>>
1:1 orthologADAMTS20100054665F6PZV0Equus caballusPredictionMore>>
1:1 orthologADAMTS2080070P59510Homo sapiensPublicationMore>>
1:1 orthologAdamts20223838P59511CPOMus musculusPublicationMore>>
1:1 orthologADAMTS20A0A2I3SSY2Pan troglodytesPredictionMore>>
1:1 orthologAdamts20D3ZN23Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0004222 metalloendopeptidase activity

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1015 Disulfide bond
KW-1185 Reference proteome
KW-0732 Signal

Interpro

InterPro ID InterPro Term
IPR041645 ADAM_CR_2
IPR010294 ADAM_spacer1
IPR013273 ADAMTS/ADAMTS-like
IPR024079 MetalloPept_cat_dom_sf
IPR001590 Peptidase_M12B
IPR002870 Peptidase_M12B_N
IPR000884 TSP1_rpt
IPR036383 TSP1_rpt_sf

PROSITE

PROSITE ID PROSITE Term
PS50215 ADAM_MEPRO
PS50092 TSP1

Pfam

Pfam ID Pfam Term
PF17771 ADAM_CR_2
PF05986 ADAM_spacer1
PF01562 Pep_M12B_propep
PF01421 Reprolysin
PF00090 TSP_1