| Tag | Content |
|---|---|
| Uniprot ID | D3ZN23 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSRNOP00000041609 |
| Ensembl nucleotide ID | ENSRNOG00000033397 |
| Gene name | ADAM metallopeptidase with thrombospondin type 1 motif, 20 |
| Gene symbol | Adamts20 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MRVAKWLTGL LCPISLLLTG SWEVRFHPRQ EALVKTLASY EVVTPTRVNE FGDVFPQNRH 60 FSRKKRSSGV PEPPPLRTHY RISAYGQLFQ LNLSADSAFL AAGYTEVHLG TPVPGPGGRS 120 AEPPDLRHCF YRGQVNARED HIAVFSLCGG LMGTFKANDG EYFLEPVLKA DGSEHEDDHN 180 KPHLIYRQEV KRNAFVRSQS HGPCGVSENQ TEKTALPSPS FRNTTGDLNR RKGAVFGLEG 240 ERSRLHSRSK RFLSYPRYVE VMVTADAKMV RHHGQNLQHY VLTLMSIVAA IYKDSSIGNL 300 INIVIVKLVI IHSEQEGPVI SFNAATTLRN FCLWQQSQNV LDDAHPSHHD TAVLITREDI 360 CGAKEKCDTL GLAELGTLCD PSRSCSISEE NGLSAAFTIA HELGHVFNVP HDDSFKCKES 420 GTKHQYHVMA PTLNYHTSPW TWSACSQKHI TEFLDTGHGE CLLDKPNGRT YDLSPQLPGS 480 VYDGNKQCEL MFGPGSQVCP YLKQCRRLWC TSAEGVHKGC RTQHMPLADG TSCGPGMHCH 540 RGLCVTRDME TRPVDGEWGP WGPYSSCSRT CGGGIRSTAR LCDRPEPRNG GRYCVGRRMK 600 FRSCNTDSCP KGKRDFREKQ CSDFDGKHFD ISGLPPNVRW LPKYSGIAVK DRCKLYCRVA 660 GTTSFYQLKD RVADGTPCGT ETNDICVQGL CRQAGCDHVL NSKAKRDKCG VCGGDNSSCQ 720 TLAGVFNSAH YGYNVVVKIP AGATNIEILQ HSYSGRPEDD NYLALSDTQG NFLLNGNFVV 780 SMAKKEINIQ GAVFEYSGSN NSIERINSTD RLEAELVLQV LCVGNLYNPD VHYIFNIPIE 840 ERSNLFSWDP YGPWQDCTKM CQGLHRRKIA CIRKSDRAVV SDQSCSHLPL PLFVTERCNT 900 DCELRWHITG KSDCSSQCGQ GYRTLDVHCM KYSVHKGQTV PVGDQYCGDQ LKPPNREPCH 960 GSCVLTRWHY SEWSQCSRSC GGGEKTRESY CVNGFGHRLA ERECQELPRV VLGNCNDFPC 1020 PGWATSEWSE CPVTCGKGMK QRQVWCQRSE DPVGDDFCDA STKPESLGPC ELRACASWHV 1080 GPWGSCTVTC GHGYQVRAVK CVSEILGTVL DDRECPRASR PSDRQVCVCI PRLSLPSCPV 1140 LSLPSCPVTE SNPWGQQSSL PCCCGNGQGL HRRKIACIRK SDRAVVSDQS CSHLPLPLFV 1200 TERVNPVGSW TSSYLSPRVT TSCGHGKTTR RVLCVNYHQL VDESYCDPEG RPVTEQECRL 1260 AACPPSYSRS PSSSEQPSHG PGRNVPLTHK PEENPDQGVQ LSIRGNQWRT GPWGACSRRC 1320 GGLQHRAVCQ DEDGRSATSC EATSKPPESH CGSGPCPQWN YGDWGGKCTQ TCGAGVKSRF 1380 VICQFPDGQM AQEHSCELPK PPSMMQCHLR ACPDDVSWYR GSWKSCSASC GKGIKYREVL 1440 CIDQVQRKLE EKYCSHLHKP RTHKPCRSGR CPSWKANKWK ECSVTCGSGV QQREVYCRLR 1500 GTGRVAEDMC EPSTRPQVQR PCWHQDCTRY QWTTGDWLDC STSCKKKETY RLVKCVNERN 1560 MQVNESLCDP LTKPVSIKKC RNSHCKYMVV TGDSSQCAGN CGLTYSQRIT YCTRIQPPKK 1620 NAFHHQLRPV NYGQCPVIPS PQVYKCDIRS CLRGATWKVG KWSKCSVTCG NGIMERRVAC 1680 RTENGWPSDL CLKRLKPDAQ KKCYANDCKL LTTCKEIQVT NNITKDGNYD LNVRGRILKI 1740 HCSGMQLENP REYLPLVKVE DNFSEIYGLR LQNPYECPFN GSRRADCACE NDYPPAGYTV 1800 FSKVRVDLAS MQIKTTDLLF SRTLFGKAVP FATAGDCYSA ARCPQGQFSI NLAGTGMKVS 1860 STAKWLAQGR YASVIIHRSQ DGTKVYGRCG GFCGKCVPHV STGLPIQVL 1909 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ADAMTS20 | 536137 | E1B900 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | ADAMTS20 | A0A452GAZ8 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | ADAMTS20 | 100054665 | F6PZV0 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | ADAMTS20 | 80070 | P59510 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Adamts20 | 223838 | P59511 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | ADAMTS20 | A0A2I3SSY2 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | Adamts20 | D3ZN23 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005615 | extracellular space |
| GO:0004175 | endopeptidase activity |
| GO:0004222 | metalloendopeptidase activity |
| GO:0008270 | zinc ion binding |
| GO:0030198 | extracellular matrix organization |
| GO:0043066 | negative regulation of apoptotic process |
| GO:0045636 | positive regulation of melanocyte differentiation |
| GO:0009967 | positive regulation of signal transduction |
| GO:0006508 | proteolysis |
| GO:0048070 | regulation of developmental pigmentation |