| Tag | Content |
|---|---|
| Uniprot ID | F6PZV0 |
| Entrez ID | 100054665 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_001488308.4 |
| Ensembl protein ID | ENSECAP00000018989 |
| Ensembl nucleotide ID | ENSECAG00000020835 |
| Gene name | ADAM metallopeptidase with thrombospondin type 1 motif 20 |
| Gene symbol | ADAMTS20 |
| Organism | Equus caballus |
| NCBI taxa ID | 9796 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MRVAKWLTGL LYQLSLFITR SWEVHFHPRQ EALVRTLASY EVVTPARVNE FGEVFPQSHH 60 FSRRKRSSEA LEPTPFRTHY RISAYGQLFQ LNLSADAAFL AAGYTEVHLG APARQPEERS 120 AAPPDLRHCF YRGQVNARED HTAVFSLCGG LMGTFKTHDS EYFLEPIMKA DGSENEDDHN 180 KPHLIYRQEL KRNYFLQSHK PCEVSESQIK KTSVPFHNYS NMNEDLNIKK EIVLGYPSKN 240 VSLEDERSQL HSRRKRFLSY PRYVEVMVTA DAKMVHHHGQ NLQHYVLTLM SIVAAIYKDS 300 SIGNLINIVI VKLVVIHNEQ EGPVISFNAA TTLRNFCLWQ QTQNVLDDAH PAHHDTAVLI 360 TREDICGARE KCDTLGLAEL GTLCDPLRSC SISEENGLSA AFTIAHELGH VFNVPHDDSF 420 KCKETGIKHQ YHVMAPTLNY HTSPWTWSKC SQKYITEFLD TGHGECLLDK PNGRIYDLSS 480 QLPGLMYDVN KQCELMFGPG SQVCPYLKQC RRLWCTSAEG VHKGCRTQHM PLADGTNCGP 540 GMHCHHGLCV NKEMETRPVD GEWGPWGPYS SCSRTCGGGI KSTTRLCNRP EPRNGGKYCV 600 GRRMKFRSCN TDSCPKGKED FREKQCSDFD GKHFNINGLS PNVRWLPKYS GIAMKDRCKL 660 YCRVAGTTNF YQLKDRVADG TPCGTETNDI CVQGLCRQAG CDHVLNSKAK RDRCGVCGGD 720 NSSCRMMAGV FNSAHYGYNV VVKIPTGATN IDILQHSYSG KPEDDNYLAL SDAQGNFLLN 780 GNFVVSMSKK EINIQGAIFE YSGSNNSIER INSTDRLEQE LVLQVLCVGN LYNPDVRYSF 840 NIPVEEKSDL FQWDPYGPWQ DCTKMCQGLH RRKITCIRKS DHMVVSDQRC DHLPLPLFVT 900 ERCNTDCELR WHIIGKSECS SHCGQGYKSL DVHCMKYSIH KGQTVPVDDH YCSDQLKPPT 960 REPCRGDCVV MSWRYSEWSQ CSRSCGGGER SRESYCINNL GHRLADRECQ EIPRVTIENC 1020 NEFSCPVWAT SEWSECLVTC GKGTKQRQVW CQLNEAHLSD GFCDPSTKPE YLRPCELHTC 1080 ASWQVGPWGS CTATCGHGYQ MRAVQCVNEL LNAVLDDRVC HGASRPSDRQ DCIVTPCPII 1140 PITGATSLPA LPVGKIAQWR HGSWTPCSVS CGRGNQARYV SCRDAHDGIA DESYCAHLPR 1200 PAEISVCFSP CGEWQTGNWS PCSASCGHGK STRQVLCINY HQPINENYCD PEVRPLVEQE 1260 CNLAACPPTY SHFPSSSEQP NHFPGRNFPL THKPEDNQNQ GVHPSIRGNQ WRTGPWGSCS 1320 SSCAGGVQRR VVVCQDENGQ SASYCDAASR PPESKHCDSG PCPRWNYGSW GECTQTCGGG 1380 IKSRFVICQF PNGQMSQEQN CEILNKPPSV VQCHVHACPD DVSWHRGPWK SCSASCGKGL 1440 KYREVLCIDQ FQGKLEEKYC SHLQKPRTHK ACRSVRCPSW KANRWKECSV TCGSGVQQRD 1500 VYCRLRGVGR VAEEKCDGST RPYFQRQCWR QDCVQYQWVA REWLDCSTSC KKKETHREVK 1560 CVDAQNIQVN ESFCDPSTRP PSIKKCRNPP CKYIVVTGDS SQCADNCGFS YRQRITYCMG 1620 IQSTEKYKLH QLWPMDYREC PVLPSPQVYR CNFRSCLHTA TWKVGKWSKC SVTCGAGITK 1680 RRVECMTENG RSSDLCLKHL KPDAQRKCYV QDCKTFTSCK EIQVKNNITR DGDYYLNIKG 1740 RVIKIYCAGM YLENPKEYIS LVKGEEDNFS EVYGFRLQNP YECPFNGSRR QDCQCKNDYL 1800 AAGHTVFSKI RIDLTSMQIK TTDLLFAQTI FGKAVPFATA GDCYSAARCP QGQFSINLAG 1860 TGMKIASTAK WLAQGTYASV IIHRSQDGTK VYGRCGGFCG KCVPHMTTGL PIQVI 1915 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ADAMTS20 | 536137 | E1B900 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | ADAMTS20 | A0A452GAZ8 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | ADAMTS20 | 100054665 | F6PZV0 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | ADAMTS20 | 80070 | P59510 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Adamts20 | 223838 | P59511 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | ADAMTS20 | A0A2I3SSY2 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | Adamts20 | D3ZN23 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005615 | extracellular space |
| GO:0004222 | metalloendopeptidase activity |
| GO:0008270 | zinc ion binding |
| GO:0030198 | extracellular matrix organization |
| GO:0043066 | negative regulation of apoptotic process |
| GO:0045636 | positive regulation of melanocyte differentiation |
| GO:0009967 | positive regulation of signal transduction |