| Tag | Content |
|---|---|
| Uniprot ID | E1B900 |
| Entrez ID | 536137 |
| Genbank protein ID | |
| Genbank nucleotide ID | NM_001206093.1 |
| Ensembl protein ID | ENSBTAP00000036833 |
| Ensembl nucleotide ID | ENSBTAG00000000395 |
| Gene name | ADAM metallopeptidase with thrombospondin type 1 motif 20 |
| Gene symbol | ADAMTS20 |
| Organism | Bos taurus |
| NCBI taxa ID | 9913 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MRVVKWLTGL LYQLSLFITR SWEVHFHPRQ EALVRTLASY EVVTPARVNE FGEVFPQSHH 60 FSRRKRSSET LEPTPFRTHY RIRAYGQLFQ LNLSADAAFL AAGYTEVHLG TSAHPAEERS 120 AAPPDLRHCF YRGQVNARED HTAVFSLCGG LMGTFKAHDG EYFLEPIMKA DGSEHEDDHN 180 KPHLIYRQEL KRNYFLQSHK PCDVSESEIK KTTLPFHNYS DVNENLNIKE ERVLGYTSKN 240 ISLEDERSQL HSRKKRFLSY PRYVEVMVTA DSKMVHHHGQ NLQHYVLTLM SIVAAIYKDS 300 SIGNLINIVI VKLVIIHDEQ EGPVISFNAA TTLRNFCLWQ QTQNVLDDAH PSHHDTAVLI 360 TREDICGARE KCDTLGLAEL GTLCDPLRSC SISEENGLSA AFTIAHELGH VFNVPHDDSF 420 KCKETGIKHQ YHVMAPTLNY HTSPWTWSKC SQKYITEFLD TGHGECLLDK PNGRIYDLSS 480 QLPGLMYDVN KQCELMFGPG SQVCPYLKQC RRLWCTSAEG VHKGCRTQHM PLADGTNCGP 540 GMHCHHGLCV NKEMETRPVD GDWGPWGPYS SCSRTCGGGI KSTSRLCNRP EPRNGGKYCV 600 GRRMKFRSCN TDSCPKGKQD FREKQCSDFD GKHFNINGLS PNVRWLPKYS GIAVKDRCKL 660 YCRVAGTTSF YQLKDRVADG TPCGTETNDI CVQGLCRQAG CDHVLNSKAR RDKCGVCGGD 720 NSSCRTMAGV FNSAHYGYNV VVKIPPGATN IDILQHSYSG KPEDDNYLAL SDTQGNFLLN 780 GNFVVSMSKR EINVQGAIFE YSGSNNSIER INSTDRLEEE LVLQVLCVGN LYNPDVRYSF 840 NIPVEEKSDL FTWDPYGPWQ DCTKMCQGLH RRKITCVRKS DHMVVSDQSC DHIPLPLLVT 900 ERCNTDCELR WHIIGKSECS ALCGQGYKSL DVHCMKYSIH NGQTVPVVDH YCSDQLKPPT 960 REPCHGDCVL TRWHYLEWSQ CSRSCGGGER SRDSYCINNF GHRLADRECQ ELPRVTVENC 1020 NEFSCPSWAT SEWSECLVTC GKGTNQRQVW CQLNEDHLSD GFCDPSTKPE SQRPCELHAC 1080 TSWQVGPWGS CTATCGQGYQ MRAVKCVNEL FSAVLDDRLC HGASRPSERQ DCIVIPCPVI 1140 PKIGATSLPA VPMRKITQWR YGSWTPCSVS CGRGNQARYV SCRDAHDGIA DESFCAHLPR 1200 PAEIAVCFSL CGEWQTGNWS PCSASCGRGK MTRQVLCINY HQPVNENYCD PEVRPVIEQE 1260 CNLAACPPTY SHFPSSSEQP SHFPGRNFPL THKPEDNQNQ GIHPSIRENQ WRTGPWGSCS 1320 SSCAGGVQHR VVVCQDENGQ SASYCDSASK PPESKHCDSG PCPQWNYGSW GECTQTCGGG 1380 IKSRFVICQF PNGQLSQEQN CEMLNKPPSV VQCHIRACPD DVSWHRGPWK SCSASCGKGL 1440 KYREVLCIDQ FHGKLEEKYC SHLQKPRTHK ACRSVQCPSW KANRWKECSV TCGSGVQQRD 1500 VYCRLRGVGR VAEEKCDPST RPYFQRECWH RNCTQYHWVA GEWLDCSISC KKRETYRQVK 1560 CVDAQNIEVS ESFCDLATRP LAIKKCRNSP CKYIVITGDS SQCAGNCGFS YRQRITYCIG 1620 VQSMEKHKLH ELWPIGYRVC PVLPSPQVYK CNFKTCLHMA TWKVGKWSKC SVTCGVGMME 1680 RRVECMADNG LSSDLCLKHL KPDAQKKCYV SDCKTFTSCK EIQMKNNITK DGDYYLNIKG 1740 RITKIYCAGM HLQNPKEYIS LVKGEEDNFS EVYGFRLRNP YECPFNGSRR QDCECKNDYM 1800 AAGHTVFSKI RIDLTSMQIK TTDLLFAQTI FGNAVPFATA GDCYSAARCP QGQFSINLAG 1860 TGMKISSTAK WLAQGSYASV IIHRSQDGTK VYGRCGGFCG KCIPHMTTGL PIQVV 1915 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ADAMTS20 | 536137 | E1B900 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | ADAMTS20 | A0A452GAZ8 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | ADAMTS20 | 100054665 | F6PZV0 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | ADAMTS20 | 80070 | P59510 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Adamts20 | 223838 | P59511 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | ADAMTS20 | A0A2I3SSY2 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | Adamts20 | D3ZN23 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005615 | extracellular space |
| GO:0004222 | metalloendopeptidase activity |
| GO:0008270 | zinc ion binding |
| GO:0030198 | extracellular matrix organization |
| GO:0043066 | negative regulation of apoptotic process |
| GO:0045636 | positive regulation of melanocyte differentiation |
| GO:0009967 | positive regulation of signal transduction |