Gene: ADAMTS20

Basic information

Tag Content
Uniprot ID A0A452GAZ8
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSCHIP00000033587
Ensembl nucleotide ID ENSCHIG00000027074
Gene name Uncharacterized protein
Gene symbol ADAMTS20
Organism Capra hircus
NCBI taxa ID 9925
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MRVVKWLTGL LYQLSLFITR SWEVHFHPRQ EALVRTLASY EVVTPARVNE FGEVFPQSHH 60
FSRRKRSSET LEPTPFRTHY RIRAYGQLFQ LNLSADAAFL AAGYTEVHLG TSAHQAEERS 120
AAPADLRHCF YRGQVNARED HTAVFSLCGG LMGTFKAHDG EYFLEPIMKA DGSEHEDDHS 180
KPHLIYRQEL KGNYFLQSHK PCDASESEIK KTTLPFHNYR YTSKNISLED ERSQLHSRKK 240
RFLSYPRYVE VMVTADSKMV HHHGQNLQHY VLTLMSIVAA IYKDSSIGNL INIVIVKLVI 300
IHDEQEGPVI SFNAATTLRN FCLWQQTQNV LDDAHPSHHD TAVLITREDI CGAREKCDTL 360
GLAELGTLCD PLRSCSISEE NGLSAAFTIA HELGHVFNVP HDDSFKCKET GIKHQYHVMA 420
PTLNYHTSPW TWSKCSQKYI TEFLDTGHGE CLLDKPNGRI YDLSSQLPGL MYDVNKQCEL 480
MFGPGSQVCP YLKQCRRLWC TSAEGVHKGC RTQHMPLADG TNCGPGMHCH HGLCVNKEME 540
TRPVDGDWGP WGPYSSCSRT CGGGIKSTSR LCNRPEPRNG GKYCVGRRMK FRSCNTDSCP 600
KGKQDFREKQ CSDFDGKHFN INGLSPNVRW LPKYSGIAVK DRCKLYCRVA GTTSFYQLKD 660
RVADGTPCGT ETNDICVQGL CRQAGCDHVL NSKARRDKCG VCGGDNSSCR TMAGVFNSAH 720
YGYNVVVKIP PGATNIDILQ HSYSGKPEDD NYLALSDTQG NFLLNGNFVV SMSKREINVQ 780
GAIFEYSGSN NSIERINSTD RLEEELVLQV LCVGNLYNPD VRYSFNIPVE EKSDLFTWDP 840
YGPWQDCTKM CQGLHRRKIT CVRKSDHMVM SDQSCDHLPL PLLVTERCNT DCELRWHIIG 900
KSECSTLCGQ GYKSLDVHCM KYSIHKGQTV PVDDHYCSDQ LKPPTREPCH GDCVLTRWHY 960
LEWSQCSRSC GGGERSRESY CINNFGHRLA DRECQELPRV TTENCNEFSC PSWATSEWSE 1020
CLVTCGKGTK QRQVWCHLNE DHLSDGFCDP STKPESQRPC ELHACTSWQV GPWGSCTATC 1080
GQGYQMRAVK CVNELFSTVL DDRLCHGASR PSERQNCIVT PCPVIPKIGA TSLPAVPMRK 1140
ITQWRYGSWT PCSVSCGRGN QARYVSCRDA HDGIADESFC AHLPRPAEIA VCFSPCGEWQ 1200
TGNWSPCSAS CGRGKMTRQV LCINYHQPVN ENYCDPEVRP VIEQECNLAA CPPTYSHFPS 1260
SSEQPSHFPG RNFPLTHKPE DNQNQRVHPS IRENQWRTGP WGSCSSSCAG GVQRRVVVCQ 1320
DENGQSASYC DAVSKPPESK HCDSGPCPQW NYGSWGECTQ TCGGGIKSRF VICQFPDGQL 1380
SQEQNCEMLN KPPSVVQCHI HACPDDVSWH RGPWKSCSAS CGKGLKYREV LCIDQFRRKL 1440
EEKYCSHLQK PRTHKACRSV RCPSWKANRW KECSVTCGSG VQQRDVYCRL RGVGRVAEEK 1500
CDPSTRPYFQ RECWHRDCIQ YHWAAGEWLD CSVSCKKRET YRQVKCMDAQ NIQVSESFCD 1560
LATRPLAVKK CRNSPCKYIV VTGDSSQCAG NCGFSYRQRI TYCVGVQSME KHKLHELWPI 1620
DYQVCPVLPS PQVYKCNFRT CLHMATWKVG KWSKCSVTCG VGMMERRVEC MADNGLSSDL 1680
CLKHLKPDAQ KKCYVSDCKT FMSCKEIQVK NNITKDGDYY LNIKGRITKI YCAGMHLQNP 1740
KEYISLVKGE EDNFSEVYGF RLRNPYECPF NGSRRHDCEC KNDYLAAGHT VFSKIRIDLT 1800
SMQIKTTDLL FAQTIFGNAV PFATAGDCYS AARCPQGQFS INLAGTGMKI SSTAKWLAQG 1860
SYASVIIHRS QDGTKVYGRC GGFCGKCIPH MTTGLPIQVV

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologADAMTS20536137E1B900Bos taurusPredictionMore>>
1:1 orthologADAMTS20A0A452GAZ8Capra hircusPredictionMore>>
1:1 orthologADAMTS20100054665F6PZV0Equus caballusPredictionMore>>
1:1 orthologADAMTS2080070P59510Homo sapiensPublicationMore>>
1:1 orthologAdamts20223838P59511CPOMus musculusPublicationMore>>
1:1 orthologADAMTS20A0A2I3SSY2Pan troglodytesPredictionMore>>
1:1 orthologAdamts20D3ZN23Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0004222 metalloendopeptidase activity
GO:0008270 zinc ion binding

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1015 Disulfide bond
KW-1185 Reference proteome
KW-0732 Signal

Interpro

InterPro ID InterPro Term
IPR041645 ADAM_CR_2
IPR010294 ADAM_spacer1
IPR013273 ADAMTS/ADAMTS-like
IPR024079 MetalloPept_cat_dom_sf
IPR012314 Pept_M12B_GON-ADAMTSs
IPR001590 Peptidase_M12B
IPR002870 Peptidase_M12B_N
IPR000884 TSP1_rpt
IPR036383 TSP1_rpt_sf

PROSITE

PROSITE ID PROSITE Term
PS50215 ADAM_MEPRO
PS51046 GON
PS50092 TSP1

Pfam

Pfam ID Pfam Term
PF17771 ADAM_CR_2
PF05986 ADAM_spacer1
PF08685 GON
PF01562 Pep_M12B_propep
PF01421 Reprolysin
PF00090 TSP_1