Gene: TOX3

Basic information

Tag Content
Uniprot ID A0A2I3STP6
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSPTRP00000080346
Ensembl nucleotide ID ENSPTRG00000008110
Gene name TOX high mobility group box family member 3
Gene symbol TOX3
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MDVRFYPAAA GDPASLDFAQ CLGYYGYSKF GNNNNYMNMA EANNAFFAAS ETFHTPSLGD 60
EEFEIPPITP PPESDPALGM PDVLLPFQAL SDPLPSQGSE FTPQFPPQSL DLPSITISRN 120
LVEQDGVLHS SGLHMDQSHT QVSQYRQDPS LIMRSIVHMT DAARSGVMPP AQLTTINQSQ 180
LSAQLGLNLG GASMPHTSPS PPASKSATPS PSSSINEEDA DEANRAIGEK RAAPDSGKKP 240
KTPKKKKKKD PNEPQKPVSA YALFFRDTQA AIKGQNPNAT FGEVSKIVAS MWDSLGEEQK 300
QVYKRKTEAA KKEYLKALAA YRASLVSKAA AESAEAQTIR SVQQTLASTN LTSSLLLNTP 360
LSQHGTVSAS PQTLQQSLPR SIAPKPLTMR LPMNQIVTSV TIAANMPSNI GAPLISSMGT 420
TMVGSAPSTQ VSPSVQTQQH QMQLQQQQQQ QQQQQMQQMQ QQQLQQHQMH QQIQQQMQQQ 480
HFQHHMQQHL QQQQQHLQQQ INQQQLQQQL QQRLQLQQLQ HMQHQSQPSP RQHSPVASQI 540
TSPIPAIGSP QPASQQHHSQ IQSQTQTQVL SQAIPTICES NCLMNPGTY 589

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologTOX3539135E1BKT2Bos taurusPredictionMore>>
1:1 orthologTOX3F1PDR6Canis lupus familiarisPredictionMore>>
1:1 orthologTOX3102186986A0A452E0C0Capra hircusPredictionMore>>
1:1 orthologTOX327324O15405Homo sapiensPublicationMore>>
1:1 orthologTox3244579Q80W03Mus musculusPredictionMore>>
1:1 orthologTOX3A0A2I3STP6Pan troglodytesPredictionMore>>
1:1 orthologA0A4X1U5I2Sus scrofaPredictionMore>>
1:1 orthologTox3F1LNE1Rattus norvegicusPredictionMore>>
1:1 orthologtox3555286E7FAU5Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005829 cytosol
GO:0005654 nucleoplasm
GO:0003682 chromatin binding
GO:0034056 estrogen response element binding
GO:0051219 phosphoprotein binding
GO:0042803 protein homodimerization activity
GO:0043524 negative regulation of neuron apoptotic process
GO:0045893 positive regulation of transcription, DNA-templated

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0175 Coiled coil
KW-0238 DNA-binding
KW-0539 Nucleus
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR009071 HMG_box_dom
IPR036910 HMG_box_dom_sf

PROSITE

PROSITE ID PROSITE Term
PS50118 HMG_BOX_2

Pfam

Pfam ID Pfam Term
PF00505 HMG_box