| Tag | Content |
|---|---|
| Uniprot ID | A0A2I3STP6 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSPTRP00000080346 |
| Ensembl nucleotide ID | ENSPTRG00000008110 |
| Gene name | TOX high mobility group box family member 3 |
| Gene symbol | TOX3 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MDVRFYPAAA GDPASLDFAQ CLGYYGYSKF GNNNNYMNMA EANNAFFAAS ETFHTPSLGD 60 EEFEIPPITP PPESDPALGM PDVLLPFQAL SDPLPSQGSE FTPQFPPQSL DLPSITISRN 120 LVEQDGVLHS SGLHMDQSHT QVSQYRQDPS LIMRSIVHMT DAARSGVMPP AQLTTINQSQ 180 LSAQLGLNLG GASMPHTSPS PPASKSATPS PSSSINEEDA DEANRAIGEK RAAPDSGKKP 240 KTPKKKKKKD PNEPQKPVSA YALFFRDTQA AIKGQNPNAT FGEVSKIVAS MWDSLGEEQK 300 QVYKRKTEAA KKEYLKALAA YRASLVSKAA AESAEAQTIR SVQQTLASTN LTSSLLLNTP 360 LSQHGTVSAS PQTLQQSLPR SIAPKPLTMR LPMNQIVTSV TIAANMPSNI GAPLISSMGT 420 TMVGSAPSTQ VSPSVQTQQH QMQLQQQQQQ QQQQQMQQMQ QQQLQQHQMH QQIQQQMQQQ 480 HFQHHMQQHL QQQQQHLQQQ INQQQLQQQL QQRLQLQQLQ HMQHQSQPSP RQHSPVASQI 540 TSPIPAIGSP QPASQQHHSQ IQSQTQTQVL SQAIPTICES NCLMNPGTY 589 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | TOX3 | 539135 | E1BKT2 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | TOX3 | F1PDR6 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | TOX3 | 102186986 | A0A452E0C0 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | TOX3 | 27324 | O15405 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Tox3 | 244579 | Q80W03 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | TOX3 | A0A2I3STP6 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | A0A4X1U5I2 | Sus scrofa | Prediction | More>> | ||||
| 1:1 ortholog | Tox3 | F1LNE1 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | tox3 | 555286 | E7FAU5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005829 | cytosol |
| GO:0005654 | nucleoplasm |
| GO:0003682 | chromatin binding |
| GO:0034056 | estrogen response element binding |
| GO:0051219 | phosphoprotein binding |
| GO:0042803 | protein homodimerization activity |
| GO:0043524 | negative regulation of neuron apoptotic process |
| GO:0045893 | positive regulation of transcription, DNA-templated |
| PROSITE ID | PROSITE Term |
|---|---|
| PS50118 | HMG_BOX_2 |
| Pfam ID | Pfam Term |
|---|---|
| PF00505 | HMG_box |