| Tag | Content |
|---|---|
| Uniprot ID | F1PDR6 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSCAFP00000014278 |
| Ensembl nucleotide ID | ENSCAFG00000009722 |
| Gene name | TOX high mobility group box family member 3 |
| Gene symbol | TOX3 |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MNMAEANNAF FAASEQTFHT PSLGDEEFEI PPITPPPESD PALGMPDVLL PFQGLSDPLP 60 SQGSEFTPQF PPQSLDLPSI TISRNLVEQD GVLHSSGLHM DQSHTQVPQY RQDHSLIMRS 120 IVHMTDAARS GIMPPTQLTT INQSQLSAQL GLNLGGASMP HTSPSPPASK SATPSPSSSI 180 NEEDADESNR AIGEKRAAPD SGKKPKTPKK KKKKDPNEPQ KPVSAYALFF RDTQAAIKGQ 240 NPNATFGEVS KIVASMWDSL GEEQKQVYKR KTEAAKKEYL KALAAYRASL VSKAAAESAE 300 AQTIRSVQQT LASTNLTSSL LLNPPLSQHG TVSASPQTLQ QSLPRSIAPK PLTMRLPMNQ 360 IVTSVTIAAN MPSNIGAPLI SSMGTTLVGS TSSTQVSPSV QTQQHQLQQL QQQQQQQQQQ 420 QQQQMQQMQQ QQLQQHQMHQ QIQQQMQQQH FQHHMQQHLQ QQQHLQQQIS QQQQLQQHIQ 480 LQQLQHLQHP SQPSPRQHSP ATSQMTSPLP AIGSPQPASQ QHQSQIQAQT QTQVLSQAIY 540 LQYVNQTV 548 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | TOX3 | 539135 | E1BKT2 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | TOX3 | F1PDR6 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | TOX3 | 102186986 | A0A452E0C0 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | TOX3 | 27324 | O15405 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Tox3 | 244579 | Q80W03 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | TOX3 | A0A2I3STP6 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | A0A4X1U5I2 | Sus scrofa | Prediction | More>> | ||||
| 1:1 ortholog | Tox3 | F1LNE1 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | tox3 | 555286 | E7FAU5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005829 | cytosol |
| GO:0005654 | nucleoplasm |
| GO:0003682 | chromatin binding |
| GO:0034056 | estrogen response element binding |
| GO:0051219 | phosphoprotein binding |
| GO:0042803 | protein homodimerization activity |
| GO:0043524 | negative regulation of neuron apoptotic process |
| GO:0045893 | positive regulation of transcription, DNA-templated |
| PROSITE ID | PROSITE Term |
|---|---|
| PS50118 | HMG_BOX_2 |
| Pfam ID | Pfam Term |
|---|---|
| PF00505 | HMG_box |