| Tag | Content |
|---|---|
| Uniprot ID | A0A452E0C0 |
| Entrez ID | 102186986 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018061930.1 |
| Ensembl protein ID | ENSCHIP00000005457 |
| Ensembl nucleotide ID | ENSCHIG00000009545 |
| Gene name | HMG box domain-containing protein |
| Gene symbol | TOX3 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MDVRFYPAAA GDPAGLDFAQ CLGYYGYSKF GNNNNYMNMA EANNAFFAAS EQTFHTPSLG 60 DEEFEIPPIT PPPESDPALG MPDVLLPFQG LSDPLPSQGS EFTPQFPPQS LDLPSITISR 120 NLVEQDGVLH SSGLHMDQSH TQVSQYRQDP SVIMRSIVHM TDAARSGIMP PAQLTTINQS 180 QLSAQLGLNL GGASVPHTSP SPPASKSATP SPSSSINEED ADESNRAIGE KRAAPDSGKK 240 PKTPKKKKKK DPNEPQKPVS AYALFFRDTQ AAIKGQNPNA TFGEVSKIVA SMWDSLGEEQ 300 KQVYKRKTEA AKKEYLKALA AYRASLVSKA AAESAEAQTI RSVQQTLAST NLTSSLLLNP 360 PLSQHGTVSA SPQTLQPSLP RSIAPKPLTM RLPVNPMVTS VTIAANMPSN LGAPLISSMV 420 GSASSAQVSP SVQTQQQQQQ QMQQLQQQQL QQQQLQQQQL QQQLQQQHFQ HHVQLQQQQL 480 QQHINQQQLQ QRLQLQQLQH MQHQSQPSPR QHSPVTSQIT SPIPALGSPQ PASQQHPSQI 540 QSQTQTQVLS QVSIF 555 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | TOX3 | 539135 | E1BKT2 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | TOX3 | F1PDR6 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | TOX3 | 102186986 | A0A452E0C0 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | TOX3 | 27324 | O15405 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Tox3 | 244579 | Q80W03 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | TOX3 | A0A2I3STP6 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | A0A4X1U5I2 | Sus scrofa | Prediction | More>> | ||||
| 1:1 ortholog | Tox3 | F1LNE1 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | tox3 | 555286 | E7FAU5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005829 | cytosol |
| GO:0005654 | nucleoplasm |
| GO:0003682 | chromatin binding |
| GO:0034056 | estrogen response element binding |
| GO:0051219 | phosphoprotein binding |
| GO:0042803 | protein homodimerization activity |
| GO:0043524 | negative regulation of neuron apoptotic process |
| GO:0045893 | positive regulation of transcription, DNA-templated |
| PROSITE ID | PROSITE Term |
|---|---|
| PS50118 | HMG_BOX_2 |
| Pfam ID | Pfam Term |
|---|---|
| PF00505 | HMG_box |