| Tag | Content |
|---|---|
| Uniprot ID | F1LNE1 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSRNOP00000034957 |
| Ensembl nucleotide ID | ENSRNOG00000028649 |
| Gene name | TOX high mobility group box family member 3 |
| Gene symbol | Tox3 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MNMAEANNAF FAASEQTFHT PSLGDEEFEI PPITPPPESD PTLGMPDVLL PFQTLSDPLP 60 SQGNEFTPQF PPQSLDLPSI TISRNLVEQD GVLHSNGLHM DQSHTQVSQY RQDPSLVMRS 120 IVHMTDAARS GIMPPAQLTT INQSQLSAQL GLNLGGASVP HTSPSPPASK SATPSPSSSI 180 NEEDADETNR AVGEKRTAPD SGKKPKTPKK KKKKDPNEPQ KPVSAYALFF RDTQAAIKGQ 240 NPNATFGEVS KIVASMWDSL GEEQKQVYKR KTEAAKKEYL KALAAYRASL VSKAAAESAE 300 AQTIRSVQQT LASTNLTSSL LLNTSLSQHG TVPASPQTLP QSLPRSIAPK PLTMRLPMSQ 360 IVTSVTIAAN MPSNIGAPLI SSMGTTMVGS VSSTQVSPSV QTQQHQLQLQ QQQQQQQQQQ 420 QMQQMQQQQL QQHQMHQQIQ QQMQQQHFQH HMQQHLQQQQ QQHLQQQISQ QQLQQQLQQH 480 LQLQQQLQHM QHQSQPSPRQ HSPVTSQITS PIPAIGSPQP ASQQHQPQIQ SQTQTQVLPQ 540 VSIF 544 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | TOX3 | 539135 | E1BKT2 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | TOX3 | F1PDR6 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | TOX3 | 102186986 | A0A452E0C0 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | TOX3 | 27324 | O15405 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Tox3 | 244579 | Q80W03 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | TOX3 | A0A2I3STP6 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | A0A4X1U5I2 | Sus scrofa | Prediction | More>> | ||||
| 1:1 ortholog | Tox3 | F1LNE1 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | tox3 | 555286 | E7FAU5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005829 | cytosol |
| GO:0005654 | nucleoplasm |
| GO:0003682 | chromatin binding |
| GO:0034056 | estrogen response element binding |
| GO:0051219 | phosphoprotein binding |
| GO:0042803 | protein homodimerization activity |
| GO:0043524 | negative regulation of neuron apoptotic process |
| GO:0045893 | positive regulation of transcription, DNA-templated |
| PROSITE ID | PROSITE Term |
|---|---|
| PS50118 | HMG_BOX_2 |
| Pfam ID | Pfam Term |
|---|---|
| PF00505 | HMG_box |