Gene: tox3

Basic information

Tag Content
Uniprot ID E7FAU5
Entrez ID 555286
Genbank protein ID
Genbank nucleotide ID XM_005169018.3
Ensembl protein ID ENSDARP00000101166
Ensembl nucleotide ID ENSDARG00000073957
Gene name TOX high mobility group box family member 3
Gene symbol tox3
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MSSASPRGNM DVFYPSAGGN SIPGDPQNLD FSHCLGYYNY NKFANNNNYM NMADANGALL 60
AGGDTFHTPS LGDEEFEIPP ITPPPETEPG MGLQDVGSPY PGLPDHPNPQ RGSFTPQFPP 120
QSLELPSITI SRNMMEHEGQ INNGHSGVVG QTHLRQYPPN PTMVMRSIIS MHNPNGMMSQ 180
NQLTTINQSQ INAQLGLNMT GSNIAHTSPS PPASKSATPS PSSSINEDDQ EEGNRVIGEK 240
RPAPDAGKKP KTPKKKKKKD PNEPQKPVSA YALFFRDTQA AIKGQNPNAT FGEVSKIVAS 300
MWDGLGEEQK QVYKSKTEAA KKEYLKALAA YRASLVSKAA AESAEAQTIR SVQQTLASTS 360
LSPALVLPSP LSQHPSMSAA AQALQQALPR AIAPKPLQMR VGGSQIVTSV TVAHQNMTPG 420
SVQSQLLGQM GPQSSVSSQL SPPMQPRHSS MQQQMQQQHQ MQQHLQHHQM QQQQMHHQQI 480
QQQMQQQHFQ HHLQQQLQQH HMQQQQQQHQ QMQQQQMQMQ HMQQMQQMHQ HQMQQQHLPQ 540
SQCSPVQHSP GTPHSASLGS PPPPPAPQQH PSQVQTHAQV LSQVSIY 587

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologTOX3539135E1BKT2Bos taurusPredictionMore>>
1:1 orthologTOX3F1PDR6Canis lupus familiarisPredictionMore>>
1:1 orthologTOX3102186986A0A452E0C0Capra hircusPredictionMore>>
1:1 orthologTOX327324O15405Homo sapiensPublicationMore>>
1:1 orthologTox3244579Q80W03Mus musculusPredictionMore>>
1:1 orthologTOX3A0A2I3STP6Pan troglodytesPredictionMore>>
1:1 orthologA0A4X1U5I2Sus scrofaPredictionMore>>
1:1 orthologTox3F1LNE1Rattus norvegicusPredictionMore>>
1:1 orthologtox3555286E7FAU5Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0031490 chromatin DNA binding
GO:0006357 regulation of transcription by RNA polymerase II

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1267 Proteomics identification
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR009071 HMG_box_dom
IPR036910 HMG_box_dom_sf

PROSITE

PROSITE ID PROSITE Term
PS50118 HMG_BOX_2

Pfam

Pfam ID Pfam Term
PF00505 HMG_box