Gene: PYGO1

Basic information

Tag Content
Uniprot ID A0A2I3T6C4; A0A2J8NSI2;
Entrez ID 467804
Genbank protein ID
Genbank nucleotide ID XM_016928270.1; XM_016928268.1;
Ensembl protein ID ENSPTRP00000084795
Ensembl nucleotide ID ENSPTRG00000042720
Gene name Pygopus family PHD finger 1
Gene symbol PYGO1
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MSAEQEKDPI SLKRVRGGDS GLDGLGGPGV QLGSPDKKKR KANTQGPSFP PLSEYAPPPN 60
PNSDHLVAAN PFDDNYNTIS YKPLPSSNPY LGPGYPGFGG YSTFRMPPHV PPRMSSPYCG 120
PYSLRNQPHP FPQNPLGMGF NRPHAFNFGP HDNSSFGNPS YNNALSQNVN MPNQHFRQNP 180
GENFSQIPPQ NASQVSNPDL ASNFVPGNNS NFTSPLESNH SFIPPPNTFG QAKAPPPKQD 240
FTQGATKITN QNSSAHPPHL NMDDTVNQSN IELKNVNRNN AVNQENSRSS STEATNNNHA 300
NGTQNKPRQP RGAADACTTE KSNKSSLHPN RHGHSSSDPV YPCGICTNEV NDDQDAILCE 360
ASCQKWFHRI CTGMTETAYG LLTAEASAVW GCDTCMADKD VQLMRTRETF GPSAVGSDA 419

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologPYGO1527394F1MHP8Bos taurusPredictionMore>>
1:1 orthologPYGO1A0A452G0X5Capra hircusPredictionMore>>
1:1 orthologPYGO126108Q9Y3Y4Homo sapiensPredictionMore>>
1:1 orthologPygo172135Q9D0P5CPOMus musculusPublicationMore>>
1:1 orthologPYGO1467804A0A2I3T6C4Pan troglodytesPredictionMore>>
1:1 orthologPYGO1100156479F1RZF2Sus scrofaPredictionMore>>
1:1 orthologPYGO1100342223G1T1W7Oryctolagus cuniculusPredictionMore>>
1:1 orthologPygo1691857F1M5T3Rattus norvegicusPredictionMore>>
1:1 orthologpygo1B7ZUU3Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0046872 metal ion binding
GO:0035064 methylated histone binding
GO:0060070 canonical Wnt signaling pathway
GO:0002244 hematopoietic progenitor cell differentiation
GO:0001822 kidney development
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0034504 protein localization to nucleus
GO:0007289 spermatid nucleus differentiation

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR019786 Zinc_finger_PHD-type_CS
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD

PROSITE

PROSITE ID PROSITE Term
PS01359 ZF_PHD_1
PS50016 ZF_PHD_2

Pfam

Pfam ID Pfam Term
PF00628 PHD