| Tag | Content |
|---|---|
| Uniprot ID | F1M5T3 |
| Entrez ID | 691857 |
| Genbank protein ID | |
| Genbank nucleotide ID | NM_001191117.1 |
| Ensembl protein ID | ENSRNOP00000069543 |
| Ensembl nucleotide ID | ENSRNOG00000051813 |
| Gene name | Pygopus family PHD finger 1 |
| Gene symbol | Pygo1 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSAEQDKEPI ALKRVRGGDS GLDGLGGPNI QLGSPDKKKR KASTQGASFP PLSEYAPPPN 60 PNADHLVAAN PFDDSYNTIS YKPLPSSNPY LSPGYPGFGG YSTFRMPPHV PPRMSSPYCG 120 PYALRNQPHP FPQNPLGMGF NRPHAFNFGP HDNSNFGNPP YNNVLTQDIN MPSQHFRQGS 180 AENFSQIPPQ NVGQVSNPDL ASNFAPGNNS NFNSPLESNH SFIPPPNSFG QAKAPLPKQD 240 FTQGAAKTTN QNSSTHPPHL NMEDPVNQSN VELKNVNRNN VVQENSRSGS AEPTNNHANG 300 TQNKPRQPRG TADLCTTDKS RKFSLHPSRH GHSSSDPVYP CGICTNEVND DQDAILCEAS 360 CQKWFHRICT GMTETAYGLL TAEASAVWGC DTCMADKDVQ LMRTREAFGP PAVGSDA 417 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PYGO1 | 527394 | F1MHP8 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | PYGO1 | A0A452G0X5 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | PYGO1 | 26108 | Q9Y3Y4 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Pygo1 | 72135 | Q9D0P5 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | PYGO1 | 467804 | A0A2I3T6C4 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | PYGO1 | 100156479 | F1RZF2 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | PYGO1 | 100342223 | G1T1W7 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Pygo1 | 691857 | F1M5T3 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | pygo1 | B7ZUU3 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0046872 | metal ion binding |
| GO:0035064 | methylated histone binding |
| GO:0060070 | canonical Wnt signaling pathway |
| GO:0002244 | hematopoietic progenitor cell differentiation |
| GO:0001822 | kidney development |
| GO:0045944 | positive regulation of transcription by RNA polymerase II |
| GO:0009791 | post-embryonic development |
| GO:0034504 | protein localization to nucleus |
| GO:0007286 | spermatid development |
| GO:0007289 | spermatid nucleus differentiation |
| Pfam ID | Pfam Term |
|---|---|
| PF00628 | PHD |