Gene: ILK

Basic information

Tag Content
Uniprot ID A0A2I3T709; A0A2J8P6D1;
Entrez ID 748941
Genbank protein ID
Genbank nucleotide ID XM_016920277.1
Ensembl protein ID ENSPTRP00000084982
Ensembl nucleotide ID ENSPTRG00000003298
Gene name Integrin linked kinase
Gene symbol ILK
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MDDIFTQCRE GNAVAVRLWL DNTENDLNQG DDHGFSPLHW ACREGRSAVV EMLIMRGARI 60
NVMNRGDDTP LHLAASHGHR DIVQKLLQYK ADINAVNEHG NVPLHYACFW GQDQVAESGQ 120
RRWARISTVF HTRTHSGRGP PALGPLWKGR WQGNDIVVKV LKVRDWSTRK SRDFNEECPR 180
LRIFSHPNVL PVLGACQSPP APHPTLITHW MPYGSLYNVL HEGTNFVVDQ SQAVKFALDM 240
ARGMAFLHTL EPLIPRHALN SRSVMIDEDM TARISMADVK FSFQCPGRMY APAWVAPEAL 300
QKKPEDTNRR SADMWSFAVL LWELVTREVP FADLSNMEIG MKVALEGLRP TIPPGISPHV 360
CKLMKICMNE DPAKRPKFDM IVPILEKMQD K 391

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologILK476836E2R5H4Canis lupus familiarisPredictionMore>>
1:1 orthologILK102177259A0A452F0A3Capra hircusPredictionMore>>
1:1 orthologILK100070066A0A3Q2H733Equus caballusPredictionMore>>
1:1 orthologILKA0A0A0MTH3Homo sapiensPredictionMore>>
1:1 orthologIlk16202O55222CPOMus musculusPublicationMore>>
1:1 orthologILK748941A0A2I3T709Pan troglodytesPredictionMore>>
1:1 orthologIlk170922Q99J82Rattus norvegicusPredictionMore>>
1:1 orthologilk393543Q6PHD6Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005524 ATP binding
GO:0004672 protein kinase activity

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR011009 Kinase-like_dom_sf
IPR035692 PK_ILK
IPR000719 Prot_kinase_dom
IPR001245 Ser-Thr/Tyr_kinase_cat_dom

PROSITE

PROSITE ID PROSITE Term
PS50297 ANK_REP_REGION
PS50088 ANK_REPEAT
PS50011 PROTEIN_KINASE_DOM

Pfam

Pfam ID Pfam Term
PF12796 Ank_2
PF07714 Pkinase_Tyr