| Tag | Content |
|---|---|
| Uniprot ID | Q6PHD6 |
| Entrez ID | 393543 |
| Genbank protein ID | AAH56593.1 |
| Genbank nucleotide ID | NM_200571.1 |
| Ensembl protein ID | ENSDARP00000153672; ENSDARP00000073983; |
| Ensembl nucleotide ID | ENSDARG00000056964 |
| Gene name | 59 kDa serine/threonine-protein kinase |
| Gene symbol | ilk |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MDDIFTQCRE GNAVAVRLWL DNTENDLNQG DDHGFSPLHW ACREGRSGVV DMLIMRGARI 60 NVMNRGDDTP LHLAASHGHR DILAKLIQCK ADTNAANEHG NTPLHYACFW AHDQVAEDLV 120 SNGAQVSICN KYGETPMDKA KPPLAANLKD LAEKQGQSLS KVPYKDNFWK GTTRTRPRNG 180 TLNKQAGIDY KQLNMLNKIN ENHSGELWKG RWQGTEIVVK MLHVREWTTR KSRDFNEEYP 240 KLRIFSHPNV LPVLGACQSP PAPHPIIITH SMPYGSLYNL LHEGTNLVVD QNQAVKFALD 300 IACGMAFLHT LEPMIPRHYL NSKSVMIDED MTARISMADV KLSFQCPGRM YSPAWVAPEA 360 LQKKPEEINR RSADMWSYAV LLWELVSREV PFADLSNMEI GMKVALEGLR PTIPPGISPH 420 ICKLMKICMN EDPAKRPKFD MIVPILEKMQ DK 452 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ILK | 476836 | E2R5H4 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | ILK | 102177259 | A0A452F0A3 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | ILK | 100070066 | A0A3Q2H733 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | ILK | A0A0A0MTH3 | Homo sapiens | Prediction | More>> | |||
| 1:1 ortholog | Ilk | 16202 | O55222 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | ILK | 748941 | A0A2I3T709 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Ilk | 170922 | Q99J82 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | ilk | 393543 | Q6PHD6 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0005925 | focal adhesion |
| GO:0030027 | lamellipodium |
| GO:0042383 | sarcolemma |
| GO:0030018 | Z disc |
| GO:0005524 | ATP binding |
| GO:0004672 | protein kinase activity |
| GO:0001568 | blood vessel development |
| GO:0055013 | cardiac muscle cell development |
| GO:0003211 | cardiac ventricle formation |
| GO:0007160 | cell-matrix adhesion |
| GO:0001885 | endothelial cell development |
| GO:0060047 | heart contraction |
| GO:0007507 | heart development |
| GO:0007229 | integrin-mediated signaling pathway |
| GO:0016203 | muscle attachment |
| GO:0006468 | protein phosphorylation |
| GO:0008016 | regulation of heart contraction |
| GO:0034446 | substrate adhesion-dependent cell spreading |
| GO:0035989 | tendon development |