| Tag | Content |
|---|---|
| Uniprot ID | A0A2I3TD93; A0A2J8K4V5; |
| Entrez ID | 742141 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_016923838.1 |
| Ensembl protein ID | ENSPTRP00000087166 |
| Ensembl nucleotide ID | ENSPTRG00000005203 |
| Gene name | MDM2 proto-oncogene |
| Gene symbol | MDM2 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MVRSRQMCNT NMSVPTDGAV TTSQIPASEQ ETLVRPKPLL LKLLKSVGAQ KDTYTMKEVL 60 FYLGQYIMTK RLYDEKQQHI VYCSNDLLGD LFGVPSFSVK EHRKIYTMIY RNLVVVNQQE 120 ENSDELSGER QRKRHKSDSI SLSFDESLAL CVIREICCER SSSSESTGTP SNPDLDAGVS 180 EHSGDWLDQD SVSDQFSVEF EVESLDSEDY SLSEEGQELS DEDDEVYRVT VYQAGESDTD 240 SFEEDPEISL ADYWKCTSCN EMNPPLPSHC NRCWALRENW LPEDKGKDKG EISEKAKLEN 300 STQAEEGFDV PDCKKTIVND SRESCVEEND DKITQASQSQ ESEDYSQPST SSSIIYSSQE 360 DVKEFEREET QDKEESMESS LPLNAIEPCV ICQGRPKNGC IVHGKTGHLM ACFTCAKKLK 420 KRNKPCPVCR QPIQMIVLTY FP 442 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | MDM2 | 540378 | F1MYE6 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | MDM2 | 102173163 | A0A452FBR9 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | MDM2 | 4193 | Q00987 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Mdm2 | 17246 | P23804 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | MDM2 | 742141 | A0A2I3TD93 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Mdm2 | 314856 | A0A0G2JVC1 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | mdm2 | B0R0S9 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0046872 | metal ion binding |
| GO:0043066 | negative regulation of apoptotic process |
| GO:0071157 | negative regulation of cell cycle arrest |
| GO:0000122 | negative regulation of transcription by RNA polymerase II |
| GO:0016567 | protein ubiquitination |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |