| Tag | Content |
|---|---|
| Uniprot ID | B0R0S9 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSDARP00000116463 |
| Ensembl nucleotide ID | ENSDARG00000033443 |
| Gene name | E3 ubiquitin-protein ligase Mdm2 |
| Gene symbol | mdm2 |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MATESCLSSS QISKVDNEKL VRPKVQLKSL LEDAGADKDV FTMKEVMFYL GKYIMSKELY 60 DKQQQHIVHC GEDPLGAVLG VKSFSVKEPR ALFALINRNL VTVKNPESQS TFSEPRSQSE 120 PDRGPGDTDS DSRSSTSQQQ RRRRRSSDPE SSSAEDESR 159 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | MDM2 | 540378 | F1MYE6 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | MDM2 | 102173163 | A0A452FBR9 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | MDM2 | 4193 | Q00987 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Mdm2 | 17246 | P23804 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | MDM2 | 742141 | A0A2I3TD93 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Mdm2 | 314856 | A0A0G2JVC1 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | mdm2 | B0R0S9 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0043066 | negative regulation of apoptotic process |
| GO:0071157 | negative regulation of cell cycle arrest |
| GO:0000122 | negative regulation of transcription by RNA polymerase II |
| GO:0016567 | protein ubiquitination |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| Pfam ID | Pfam Term |
|---|---|
| PF02201 | SWIB |