| Tag | Content |
|---|---|
| Uniprot ID | A0A2I3TIH1 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSPTRP00000089061 |
| Ensembl nucleotide ID | ENSPTRG00000015696 |
| Gene name | EPH receptor B3 |
| Gene symbol | EPHB3 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | LRAAHRPPAP VAAPPASLPA CLWAPTLMDT KWVTSELAWT SHPESGWEEV SGYDEAMNPI 60 RTYQVCNVRE SSQNNWLRTG FIWRRDVQRV YVELKFTVRD CNSIPNIPGS CKETFNLFYY 120 EADSDVASAS SPFWMENPYV KVDTIAPDES FSRLDAGRVN TKVRSFGPLS KAGFYLAFQD 180 QGACMSLISV RAFYKKCAST TAGFALFPET LTGAEPTSLV IAPGTCIPNA VEVSVPLKLY 240 CNGDGEWMVP VGACTCATGH EPAAKESQCR PCPPGSYKAK QGEGPCLPCP PNSRTTSPAA 300 SICTCHNNFY RADSDSADSA CTTVPSPPRG VISNVNETSL ILEWSEPRDL GGRDDLLYNV 360 ICKKCHGAGG ASACSRCDDN VEFVPRQLGL TERRVHISHL LAHTRYTFEV QAVNGVSGKS 420 PLPPRYAAVN ITTNQAAPSE VPTLRLHSSS GSSLTLSWAP PERPNGVILD YEMKYFEKSE 480 GIASTVTSQM NSVQLDGLRP DARYVVQVRA RTVAGYGQYS RPAEFETTSE RGSGAQQLQE 540 QLPLIVGSAT AGLVFVVAVV VIAIVCLRKQ RHGSDSEYTE KLQQYITPGM KVYIDPFTYE 600 DPNEAVREFA KEIDVSCVKI EEVIGAGEFG EVCRGRLKQP GRREVFVAIK TLKVGYTERQ 660 RRDFLSEASI MGQFDHPNII RLEGVVTKSR PVMILTEFME NCALDSFLRL NDGQFTVIQL 720 VGMLRGIAAG MKYLSEMNYV HRDLAARNIL VNSNLVCKVS DFGLSRFLED DPSDPTYTSS 780 LGGKIPIRWT APEAIAYRKF TSASDVWSYG IVMWEVMSYG ERPYWDMSNQ DVINAVEQDY 840 RLPPPMDCPT ALHQLMLDCW VRDRNLRPKF SQIVNTLDKL IRNAASLKVI ASAQSGMSQP 900 LLDRTVPDYT TFTTVGDWLD AIKMGRYKES FVSAGFASFD LVAQMTAEDL LRIGVTLAGH 960 QKKILSSIQD MRLQMNQTLP VQV 983 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | EPHB3 | 540907 | F1ML02 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | EPHB3 | A0A452DRK7 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | EPHB3 | 2049 | P54753 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Ephb3 | 13845 | P54754 | CPO | E12.5, E13.5, E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | EPHB3 | A0A2I3TIH1 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | Ephb3 | 287989 | D3ZH39 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005887 | integral component of plasma membrane |
| GO:0005524 | ATP binding |
| GO:0005003 | ephrin receptor activity |
| InterPro ID | InterPro Term |
|---|---|
| IPR027936 | Eph_TM |
| IPR034245 | EphB3_rcpt_lig-bd |
| IPR001090 | Ephrin_rcpt_lig-bd_dom |
| IPR003961 | FN3_dom |
| IPR036116 | FN3_sf |
| IPR008979 | Galactose-bd-like_sf |
| IPR013783 | Ig-like_fold |
| IPR011009 | Kinase-like_dom_sf |
| IPR000719 | Prot_kinase_dom |
| IPR017441 | Protein_kinase_ATP_BS |
| IPR001660 | SAM |
| IPR013761 | SAM/pointed_sf |
| IPR001245 | Ser-Thr/Tyr_kinase_cat_dom |
| IPR011641 | Tyr-kin_ephrin_A/B_rcpt-like |
| IPR008266 | Tyr_kinase_AS |
| IPR020635 | Tyr_kinase_cat_dom |
| IPR016257 | Tyr_kinase_ephrin_rcpt |
| IPR001426 | Tyr_kinase_rcpt_V_CS |