| Tag | Content |
|---|---|
| Uniprot ID | A0A2I3TLY8 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSPTRP00000090252 |
| Ensembl nucleotide ID | ENSPTRG00000017022 |
| Gene name | Betaine--homocysteine S-methyltransferase 2 |
| Gene symbol | BHMT2 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Involved in the regulation of homocysteine metabolism. |
| Sequence | LCPAMGRCFF SLLQGILERL ESGEVVIGDG SFLITLEKRG YVKAGLWTPE AVIEHPDAVR 60 QLHMEFLRAG SNVMQTFTFS ASEDNMESKW EDVNAAACDL AREVAGKGDA LVAGGICQTS 120 IYKYHKDEAR IKKLFRQQLE VFAWKNVDFL IAEYFEHVEE AVWAVEVLKE SDRPVAVTMC 180 IGPEGDMHDI TPGECAVRLV KAGASIVGVN CRFGPDTSLK TMELMKEGLE RAGLKAHLMV 240 QPLGFHTPDC GKEGFVDLPE YPFGLESRVA TRWDIQKYAR EAYNLGVRYI GGCCGFEPYH 300 IRAIAEELAP ERGFLPPASE KHGSWGSGLD MHTKPWIRAR ARREYWENLL PASGRPFCPS 360 LSKPDF 366 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | BHMT2 | 488934 | E2RSV3 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | BHMT2 | A0A452GA59 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | BHMT2 | 23743 | Q9H2M3 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Bhmt2 | 64918 | Q91WS4 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | BHMT2 | A0A2I3TLY8 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | bhmt-2 | 100523776 | E7D6R3 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Bhmt2 | F1LMG2 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0047150 | betaine-homocysteine S-methyltransferase activity |
| GO:0008270 | zinc ion binding |
| GO:0009086 | methionine biosynthetic process |
| GO:0032259 | methylation |
| PROSITE ID | PROSITE Term |
|---|---|
| PS50970 | HCY |
| Pfam ID | Pfam Term |
|---|---|
| PF02574 | S-methyl_trans |