| Tag | Content |
|---|---|
| Uniprot ID | A0A452GA59 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSCHIP00000033480 |
| Ensembl nucleotide ID | ENSCHIG00000027021 |
| Gene name | Betaine--homocysteine S-methyltransferase 2 |
| Gene symbol | BHMT2 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Involved in the regulation of homocysteine metabolism. |
| Sequence | TPPVPGNSEE RGLLERLDSG EVVVGDGSYL LTLEKRGYVK AGLWAPEAVV EHPNAVCQLH 60 MEFLRAGSDV MQTFTFSASE DNMENRMVLE KTASLWEAVN TAACDLAREV ADKGDALVAG 120 GICQTSLYAH HKDEVRIKKL FQLQLETFAR KNVDFLIAEY FEHAVEAVWA VEVLKESGKP 180 VAATVCIGPE GDMHGVTPGE CAVKLMKAGA SVVDVNSLQA AGLKEHLMVQ SLGFHMPDCG 240 NRGFLDIPEY PFPRVATRWD IQKYTREAYS PGVRYIGGCC GFELYHIRAI AEELAPERGF 300 LPPASEKHGS WGSGLNMHTK PWIRARPRRE YWENMWPASG RPLCPSLSKE NTETAERKEI 360 PLKPHLEPFR ASILSPP 377 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | BHMT2 | 488934 | E2RSV3 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | BHMT2 | A0A452GA59 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | BHMT2 | 23743 | Q9H2M3 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Bhmt2 | 64918 | Q91WS4 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | BHMT2 | A0A2I3TLY8 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | bhmt-2 | 100523776 | E7D6R3 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Bhmt2 | F1LMG2 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0047150 | betaine-homocysteine S-methyltransferase activity |
| GO:0061627 | S-methylmethionine-homocysteine S-methyltransferase activity |
| GO:0008270 | zinc ion binding |
| GO:0071267 | L-methionine salvage |
| GO:0032259 | methylation |
| GO:0046500 | S-adenosylmethionine metabolic process |
| GO:0033477 | S-methylmethionine metabolic process |
| PROSITE ID | PROSITE Term |
|---|---|
| PS50970 | HCY |
| Pfam ID | Pfam Term |
|---|---|
| PF02574 | S-methyl_trans |