| Tag | Content |
|---|---|
| Uniprot ID | F1LMG2 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSRNOP00000058419 |
| Ensembl nucleotide ID | ENSRNOG00000040120 |
| Gene name | S-methylmethionine--homocysteine S-methyltransferase BHMT2 |
| Gene symbol | Bhmt2 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Involved in the regulation of homocysteine metabolism. |
| Sequence | MAPAGGPRVK KGILERLDSG EVVVGDGGFL FTLEKRGFVK AGLWTPEAVV EYPSAVRQLH 60 TEFLRAGADV LQTFTFSAAE DRMESKWEAV NAAACDLAQE VADGGAALVA GGICQTSLYK 120 YHKDETRIKN IFRLQLGVFA RKNVDFLIAE YFEHVEEAVW AVEVLREVGA PVTMCIGPEG 180 DMHGVTPGEC AVRLSRAGAN IIGVNCRFGP WTSLQTMKLM KEGLRDAGLQ AHLMVQCLGF 240 HTPDCGKGGF VDLPEYPFGL EPRVATRWDI QKYAREAYNL GVRYIGGCCG FEPYHIRAIA 300 EELAPERGFL PPASEKHGIW GSGLDMHTKP WIRARARREY WETLLPASGR PFCPSLSKPD 360 A 361 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | BHMT2 | 488934 | E2RSV3 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | BHMT2 | A0A452GA59 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | BHMT2 | 23743 | Q9H2M3 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Bhmt2 | 64918 | Q91WS4 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | BHMT2 | A0A2I3TLY8 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | bhmt-2 | 100523776 | E7D6R3 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Bhmt2 | F1LMG2 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0047150 | betaine-homocysteine S-methyltransferase activity |
| GO:0061627 | S-methylmethionine-homocysteine S-methyltransferase activity |
| GO:0008270 | zinc ion binding |
| GO:0071267 | L-methionine salvage |
| GO:0032259 | methylation |
| GO:0046500 | S-adenosylmethionine metabolic process |
| GO:0033477 | S-methylmethionine metabolic process |
| PROSITE ID | PROSITE Term |
|---|---|
| PS50970 | HCY |
| Pfam ID | Pfam Term |
|---|---|
| PF02574 | S-methyl_trans |