| Tag | Content |
|---|---|
| Uniprot ID | E7D6R3 |
| Entrez ID | 100523776 |
| Genbank protein ID | ADU33183.1 |
| Genbank nucleotide ID | NM_001204771.1 |
| Ensembl protein ID | |
| Ensembl nucleotide ID | |
| Gene name | Betaine homocysteine methyltransferase-2 |
| Gene symbol | bhmt-2 |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Involved in the regulation of homocysteine metabolism. |
| Sequence | MAPAGSPRAK KGILERLDAG EVVVGDGGFL LTLEKRGYVK AGLWTPEAVV EHPNAVRQLH 60 MEFLRAGSNV MQTFTFSANE DNMESQWEAV NAAACDLAQE VAGKGDALVA GGLCQTSLYK 120 HHKDEDRIKK LFRLQLEVFV RKNVDFLIAE YFEYAEEAVW AVEVLKESGK PVAATMCIGP 180 EGDMHGVTPG ECAVKLVKAG ASIIGVNCRF GPWTSLKTMR LMKEGLQAAG LKAHLMVQSL 240 VFHMPDCGKG GFVDLPEYPF ALEPRVATRW DIQKYAREAY NLGIRYIGGC CGFEPYHIRA 300 IAEELAPERG FLPPASEKHG SWGSGLNMHT KPWIRARARR EYWENLLPAS GRPFCPSLSK 360 PDV 363 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | BHMT2 | 488934 | E2RSV3 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | BHMT2 | A0A452GA59 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | BHMT2 | 23743 | Q9H2M3 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Bhmt2 | 64918 | Q91WS4 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | BHMT2 | A0A2I3TLY8 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | bhmt-2 | 100523776 | E7D6R3 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Bhmt2 | F1LMG2 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0047150 | betaine-homocysteine S-methyltransferase activity |
| GO:0008270 | zinc ion binding |
| GO:0009086 | methionine biosynthetic process |
| GO:0032259 | methylation |
| PROSITE ID | PROSITE Term |
|---|---|
| PS50970 | HCY |
| Pfam ID | Pfam Term |
|---|---|
| PF02574 | S-methyl_trans |