| Tag | Content |
|---|---|
| Uniprot ID | A0A2J8JHA7; A0A2I3RAB3; |
| Entrez ID | 465254 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_016961230.1; XM_016961228.1; |
| Ensembl protein ID | ENSPTRP00000061419 |
| Ensembl nucleotide ID | ENSPTRG00000046951 |
| Gene name | Patched 1 |
| Gene symbol | PTCH1 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MFNPQLMIQT PKEEGANVLT TEALLQHLDS ALQASRVHVY MYNRQWKLEH LCYKSGELIT 60 ETGYMDQIIE YLYPCLIITP LDCFWEGAKL QSGTAYLLGK PPLRWTNFDP LEFLEELKKI 120 NYQVDSWEEM LNKAEVGHGY MDRPCLNPAD PDCPATAPNK NSTKPLDMAL VLNGGCHGLS 180 RKYMHWQEEL IVGGTVKNST GKLVSAHALQ TMFQLMTPKQ MYEHFKGYEY VSHINWNEDK 240 AAAILEAWQR TYVEVVHQSV AQNSTQKVLS FTTTTLDDIL KSFSDVSVIR VASGYLLMLA 300 YACLTMLRWD CSKSQGAVGL AGVLLVALSV AAGLGLCSLI GISFNAATTQ VLPFLALGVG 360 VDDVFLLAHA FSETGQNKRI PFEDRTGECL KRTGASVALT SISNVTAFFM AALIPIPALR 420 AFSLQAAVVV VFNFAMVLLI FPAILSMDLY RREDRRLDIF CCFTSPCVSR VIQVEPQAYT 480 DTHDNTRYSP PPPYSSHSFA HETQITMQST VQLRTEYDPH THVYYTTAEP RSEISVQPVT 540 VTQDTLSCQS PESTSSTRDL LSQFSDSSLH CLEPPCTKWT LSSFAEKHYA PFLLKPKAKV 600 VVIFLFLGLL GVSLYGTTRV RDGLDLTDIV PRETREYDFI AAQFKYFSFY NMYIVTQKAD 660 YPNIQHLLYD LHRSFSNVKY VMLEENKQLP KMWLHYFRDW LQGLQDAFDS DWETGKIMPN 720 NYKNGSDDGV LAYKLLVQTG SRDKPIDISQ LTKQRLVDAD GIINPSAFYI YLTAWVSNDP 780 VAYAASQANI RPHRPEWVHD KADYMPETRL RIPAAEPIEY AQFPFYLNGL RDTSDFVEAI 840 EKVRTICSNY TSLGLSSYPN GYPFLFWEQY IGLRHWLLLF ISVVLACTFL VCAVFLLNPW 900 TAGIIVMVLA LMTVELFGMM GLIGIKLSAV PVVILIASVG IGVEFTVHVA LAFLTAIGDK 960 NRRAVLALEH MFAPVLDGAV STLLGVLMLA GSEFDFIVRY FFAVLAILTI LGVLNGLVLL 1020 PVLLSFFGPY PEVSPANGLN RLPTPSPEPP PSVVRFAMPP GHMHSGSDSS DSEYSSQTTV 1080 SGLSEELRHY EAQQGAGGPA HQVIVEATEN PVFAHSTVVH PESRHHPPSN PRQQPHLDSG 1140 SLPPGRQGQQ PRRDPPREGL WPPPYRPRRD AFEISTEGHS GPSNRDRWGP CGARSHNPRN 1200 PASTAMGSSV PGYCQPITTV TASASVTVAV HPPPVPGPGR NPRGGLCPGY PETDHGLFED 1260 PHVPFHVRCE RRDSKVEVIE LQDVECEERP RGSSSN 1296 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PTCH1 | A0A452EIX7 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | PTCH1 | 5727 | Q13635 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Ptch1 | 19206 | Q61115 | CPO,CLP,CLO | E13.0, E13.5, E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | PTCH1 | 465254 | A0A2J8JHA7 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Ptch1 | 89830 | Q6UY90 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | ptch1 | F8W5M6 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0008158 | hedgehog receptor activity |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| PROSITE ID | PROSITE Term |
|---|---|
| PS50156 | SSD |
| Pfam ID | Pfam Term |
|---|---|
| PF02460 | Patched |