| Tag | Content |
|---|---|
| Uniprot ID | A0A452EIX7 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSCHIP00000011903 |
| Ensembl nucleotide ID | ENSCHIG00000013837 |
| Gene name | SSD domain-containing protein |
| Gene symbol | PTCH1 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MGKATGRKAP LWLRAKFQRL LFKLGCYIQK NCGKFLVVGL LIFGAFAVGL KAANLETNVE 60 ELWVEVGGRV SRELNYTRQK IGEEAMFNPQ LMIQTPKEEG ANVLTTEALR QHLDSALQAS 120 RVHVYMYNRQ WKLEHLCYKS GELITETGYM DQIIEYLYPC LIITPLDCFW EGAKLQSGTA 180 YLLGKPPLQW TNFDPLEFLE ELKKINYQVD SWEEMLNKAE VGHGYMDRPC LNPADPDCPA 240 TAPNKNTTKP LDMALVLNGG CHGLSRKYMH WQEELIVGGT VKNSTGKLVS AHALQTMFQL 300 MTPKQMYEHF KGYEYVSHIN WNEDKAAAIL EAWQRTYVEV VHQSVAQNST QKVLSFTTTT 360 LDDILKSFSD VSVIRVASGY LLMLAYACLT MLRWDCSKSQ GAVGLAGVLL VALSVAAGLG 420 LCSLIGISFN AATTQVLPFL ALGVGVDDVF LLAHAFSETG QNKRIPFEDR TGECLKRTGA 480 SVALTSISNV TAFFMAALIP IPALRAFSLQ AAVVVVFNFA MVLLIFPAIL SMDLYRREDR 540 RLDIFCCFTS PCVSRVIQVE PQAYTETHDN TRYSPPPPYS SHSFAHETQI TMQSTVQLRT 600 EYDPHTHVYY TTAEPRSEIS VQPVTMAQDT LSCQSPESTS STRDLLSQFS DSSLHCLEPP 660 CTRWTLSSFA EKHYAPFLLK PKAKVVVIFL FLGLLGVSLY GTTRVRDGLD LTDIVPRETR 720 EYDFIAAQFK YFSFYNMYIV TQKADYPNIQ HLLYDLHKSF SNVKYVMLEE NKQLPKMWLH 780 YFRDWLQGLQ DAFDSDWETG KIMPNNYKNG SDDGVLAYKL LVQTGSRDKP IDISQLTKRR 840 LVDADGIINP SAFYIYLTAW VSNDPVAYAA SQANIRPHRP EWVHDKADYM PETRLRIPAA 900 EPIEYAQFPF YLNGLRDTSD FVEAIEKVRT ICNNYTSLGL SSYPNGYPFL FWEQYIGLRH 960 WLLLSISVVL ACTFLVCAVF LLNPWTAGII VTVLALMTVE LFGMMGLIGI KLSAVPVVIL 1020 IASVGIGVEF TVHVALAFLT AIGDKNRRAV LALEHMFAPV LDGAVSTLLG VLMLAGSEFD 1080 FIVRYFFAVL AILTILGVLN GLVLLPVLLS FFGPYPEVVH PEPRHHPLSN PRQQSHLDSR 1140 TLPPGQPGQQ PRRETPRECL RPPPYKPRRD AFEISTEGHS GPSNRDRTGP RGARSHNPRH 1200 HNPAFTAMGS SMPSYCQPIT TVTASASVTV AVHPPPAPGP GPSRNPRSGL CPGYEDYPET 1260 DHGLFEDPHV PFNVRCERRE PKVEVIELQD VECEERRQGS SSN 1303 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PTCH1 | A0A452EIX7 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | PTCH1 | 5727 | Q13635 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Ptch1 | 19206 | Q61115 | CPO,CLP,CLO | E13.0, E13.5, E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | PTCH1 | 465254 | A0A2J8JHA7 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Ptch1 | 89830 | Q6UY90 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | ptch1 | F8W5M6 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0008158 | hedgehog receptor activity |
| PROSITE ID | PROSITE Term |
|---|---|
| PS50156 | SSD |
| Pfam ID | Pfam Term |
|---|---|
| PF02460 | Patched |