| Tag | Content |
|---|---|
| Uniprot ID | A0A2J8KJZ2; H2QYU5; |
| Entrez ID | 473683 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_016944176.1; XM_016944175.1; |
| Ensembl protein ID | ENSPTRP00000037938 |
| Ensembl nucleotide ID | ENSPTRG00000022058 |
| Gene name | T-box transcription factor 22 |
| Gene symbol | TBX22 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MALSSRARAF SVEALVGRPS KRKLQDPIQA EQPELQEKKG GEEEEERRSS ASGKSEPLEK 60 QPKTEPSTSA SSGCGSDSGD GNSSESLEEK DIQMELQGSE LWKRFHDIGT EMIITKAGRR 120 MFPSVRVKVK GLDPGKQYHV AIDVVPVDSK RYRYVYHSSQ WMVAGNTDHL CIIPRFYVHP 180 DSPCSGETWM RQIISFDRMK LTNNEMDDKG HIILQSMHKY KPRVHVIEQG SSVDLSQIQS 240 LPTEGVKTFS FKETEFTTVT AYQNQQITKL KIERNPFAKG FRDTGRNRGA LDGLLETYPW 300 RPSFTLDFKT FGADTQSGSS GSSPVTSSGG APSPLNSLLS PLCFSPMFHS PTSSLGMPCP 360 EAYLPNVNLP LCYKICPTNF WQQQPLVLPA PERLASSNSS QSLAPLMMEV PMLSSLGVTN 420 SKSGSSEDSS DQYLQAPNST SQMLYGLQSP GNIFLPNSIT PEALSCSFHP SYDFYRYNFS 480 MPSRLISGSN HLKVNDDSQV SFGEGKCNHV HWYPAINHYL |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | TBX22 | 100299988 | G3N243 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | TBX22 | A0A452EVR5 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | TBX22 | 50945 | Q9Y458 | CPO,CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Tbx22 | 245572 | Q8K402 | CPO | E11.5, E12.5, E14.0, E13.5, E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | TBX22 | 473683 | A0A2J8KJZ2 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | A0A4X1W2E6 | Sus scrofa | Prediction | More>> | ||||
| 1:1 ortholog | TBX22 | 100341565 | G1T5X7 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Tbx22 | 302369 | D3ZMK6 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0003700 | DNA-binding transcription factor activity |
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding |
| GO:0000122 | negative regulation of transcription by RNA polymerase II |
| Pfam ID | Pfam Term |
|---|---|
| PF00907 | T-box |