| Tag | Content |
|---|---|
| Uniprot ID | G1T5X7 |
| Entrez ID | 100341565 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_002720231.2 |
| Ensembl protein ID | ENSOCUP00000011777 |
| Ensembl nucleotide ID | ENSOCUG00000013685 |
| Gene name | T-box transcription factor 22 |
| Gene symbol | TBX22 |
| Organism | Oryctolagus cuniculus |
| NCBI taxa ID | 9986 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MALSSRAHAF SVEALVGRTS KRKLQDPRAK AQSELQEKEG REEQEERRSG AARKSEQPEK 60 RPKTEPSTTL SGCGGGGGDG NSRDSLEEKD VIHVELQGSE LWKRFHDIGT EMIITKAGRR 120 MFPSVRVKVK GLDPGKQYYV AIDVVPVDSK RYRYVYHSSQ WMVAGNTDHS CITPRFYVHP 180 DSPCSGETWM RQIISFDRVK LTNNEMDDKG HIILQSMHKY KPRVHVMEQD SRVDLSRIQS 240 LPAEGIKTFS FKETEFTTVT AYQNQQITKL KIDRNPFAKG FRDPGRNRGV LDGLLETYPW 300 RPSLTLDFKT FGADTQSGSS GSSPVTSSGG APSPLNSLLS PPCSPPTFHL PTSSLGMPCP 360 ETYLHNINLP LCYKICPADF WRQQPFVLPT SERLASSNSS HPLAPLMMEV PMLSSLGVVG 420 SKSGSSEDFN GQCLQTSNSA SQMLYGLQAS GNIFPPNSIA REALSCSFHP PYGFYRYNFS 480 MPSRLVNAAN HLKVNDNSQV SFRESKCNHA HWHSTINHCL |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | TBX22 | 100299988 | G3N243 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | TBX22 | A0A452EVR5 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | TBX22 | 50945 | Q9Y458 | CPO,CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Tbx22 | 245572 | Q8K402 | CPO | E11.5, E12.5, E14.0, E13.5, E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | TBX22 | 473683 | A0A2J8KJZ2 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | A0A4X1W2E6 | Sus scrofa | Prediction | More>> | ||||
| 1:1 ortholog | TBX22 | 100341565 | G1T5X7 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Tbx22 | 302369 | D3ZMK6 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0003700 | DNA-binding transcription factor activity |
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding |
| GO:0000122 | negative regulation of transcription by RNA polymerase II |
| Pfam ID | Pfam Term |
|---|---|
| PF00907 | T-box |